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S -Nitrosothiols in the Blood: Roles, Amounts, and Methods of Analysis
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“Of note, since the endogenous RSNO levels are low (e.g., 1–10 µmol/L for SNO-albumin),280 this approach requires consistent supply of infused RSNOs to provide continuous catalytic generation of NO at the flowing blood/polymer tubing interface.254”
From Recent advances in thromboresistant and antimicrobial polymers for biomedical applications: just say yes to nitric oxide (NO) (2016) · cites this paper as [280]
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Citations
Cites
Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation
Cosby, K., Partovi, K. S., Crawford, J. H., Patel, R. P., Reiter, C. D., Martyr, S., Yang, B. K., Waclawiw, M. A., Zalos, G., Xu, X., et al. (2003) · Nature Medicine · doi:10.1038/nm954 · Cited by 1,807
S-nitrosohaemoglobin: a dynamic activity of blood involved in vascular control
Jia, L., Bonaventura, C., Bonaventura, J., & Stamler, J. S. (1996) · Nature · doi:10.1038/380221a0 · Cited by 1,592
Self-citationStamler, J. S., Simon, D. I., Osborne, J. A., Mullins, M. E., Jaraki, O., Michel, T. M., Singel, D. J., & Loscalzo, J. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.1.444 · Cited by 1,471
Self-citationNitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin.
Stamler, J. S., Jaraki, O., Osborne, J., Simon, D. I., Keaney, J., Vita, J., Singel, D., Valeri, C. R., & Loscalzo, J. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.16.7674 · Cited by 1,238
Self-citationEndogenous nitrogen oxides and bronchodilator S-nitrosothiols in human airways.
Gaston, B. M., Reilly, J., Drazen, J. M., Fackler, J. C., Ramdev, P., Arnelle, D. R., Mullins, M. E., Sugarbaker, D. J., Chee, C., Singel, D. J., et al. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.23.10957 · Cited by 620
Self-citationExport by red blood cells of nitric oxide bioactivity
Pawloski, J. R., Hess, D. T., & Stamler, J. S. (2001) · Nature · doi:10.1038/35054560 · Cited by 579
Self-citationReactions between nitric oxide and haemoglobin under physiological conditions
Gow, A. J., & Stamler, J. S. (1998) · Nature · doi:10.1038/34402 · Cited by 562
Self-citationS-nitrosylation in health and disease
Foster, M. W., McMahon, T., & Stamler, J. S. (2003) · Trends in Molecular Medicine · doi:10.1016/s1471-4914(03)00028-5 · Cited by 558
Self-citationEssential Roles of S-Nitrosothiols in Vascular Homeostasis and Endotoxic Shock
Liu, L., Yan, Y., Zeng, M., Zhang, J., Hanes, M. A., Ahearn, G. S., McMahon, T., Dickfeld, T. L., Marshall, H. E., Que, L. G., et al. (2004) · Cell · doi:10.1016/s0092-8674(04)00131-x · Cited by 546
Self-citationNitric oxide in the human respiratory cycle
McMahon, T., Moon, R. E., Luschinger, B. P., Carraway, M. S., Stone, A. E., Stolp, B. W., Gow, A. J., Pawloski, J. R., Watke, P., Singel, D. J., et al. (2002) · Nature Medicine · doi:10.1038/nm718 · Cited by 462
Self-citationThe oxyhemoglobin reaction of nitric oxide
Gow, A. J., Luchsinger, B. P., Pawloski, J. R., Singel, D. J., & Stamler, J. S. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.16.9027 · Cited by 418
Self-citationNagababu, E., Ramasamy, S., Abernethy, D. R., & Rifkind, J. M. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307572200 · Cited by 349
Cannon, R. O., Schechter, A. N., Panza, J. A., Ognibene, F. P., Pease-Fye, M. E., Waclawiw, M. A., Shelhamer, J. H., & Gladwin, M. T. (2001) · Journal of Clinical Investigation · doi:10.1172/jci200112761 · Cited by 298
Cannon, R. O., Schechter, A. N., Panza, J. A., Ognibene, F. P., Pease‐Fye, M. E., Waclawiw, M. A., Shelhamer, J. H., & Gladwin, M. T. (2001) · Journal of Clinical Investigation · doi:10.1172/jci12761 · Cited by 290
Luchsinger, B. P., Rich, E. N., Gow, A. J., Williams, E. M., Stamler, J. S., & Singel, D. J. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0233287100 · Cited by 202
Self-citationNitrosothiol Formation Catalyzed by Ceruloplasmin
Inoue, K., Akaike, T., Miyamoto, Y., Okamoto, T., Sawa, T., Otagiri, M., Suzuki, S., Yoshimura, T., & Maeda, H. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.38.27069 · Cited by 200
Polynitrosylated proteins: characterization, bioactivity, and functional consequences.
Simon, D. I., Mullins, M. E., Jia, L., Gaston, B. M., Singel, D. J., & Stamler, J. S. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.10.4736 · Cited by 190
Self-citationNO adducts in mammalian red blood cells: too much or too little?
Rassaf, T., Bryan, N. S., Maloney, R. E., Specian, V., Kelm, M., Kalyanaraman, B., Rodriguez, J., & Feelisch, M. (2003) · Nature Medicine · doi:10.1038/nm0503-481 · Cited by 151
Rafikova, O., Rafikov, R., & Nudler, E. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.092048999 · Cited by 135
S-nitrosation of glutathione by nitric oxide, peroxynitrite, and •NO/O2•−
Schrammel, A. (2003) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(03)00038-8 · Cited by 131
The decomposition of thionitrites
Stamler, J. S., & Toone, E. J. (2002) · Current Opinion in Chemical Biology · doi:10.1016/s1367-5931(02)00383-6 · Cited by 125
Self-citationElevated Levels of S -Nitrosoalbumin in Preeclampsia Plasma
Tyurin, V. A., Liu, S.-X., Tyurina, Y. Y., Sussman, N. B., Hubel, C. A., Roberts, J. M., Taylor, R. N., & Kagan, V. E. (2001) · Circulation Research · doi:10.1161/hh1101.092179 · Cited by 120
Red Blood Cell Nitric Oxide as an Endocrine Vasoregulator
Datta, B. N., Tufnell-Barret, T., Bleasdale, R. A., Jones, C. J. H., Beeton, I., Paul, V., Frenneaux, M. P., & James, P. E. (2004) · Circulation · doi:10.1161/01.cir.0000124450.07016.1d · Cited by 102
Enhanced S -Nitroso-Albumin Formation From Inhaled NO During Ischemia/Reperfusion
Ng, E. S. M., Jourd’heuil, D., McCord, J. M., Hernandez, D., Yasui, M., Knight, D., & Kubes, P. (2004) · Circulation Research · doi:10.1161/01.res.0000117771.63140.d6 · Cited by 97
Hallström, S., Gasser, H., Neumayer, C., Fügl, A., Nanobashvili, J., Jakubowski, A., Huk, I., Schlag, G., & Maliñski, T. (2002) · Circulation · doi:10.1161/01.cir.0000018745.11739.9b · Cited by 93
Crystallographic Analysis of the Interaction of Nitric Oxide with Quaternary-T Human Hemoglobin,
Chan, N., Kavanaugh, J. S., Rogers, P. H., & Arnone, A. (2003) · Biochemistry · doi:10.1021/bi030172j · Cited by 89
Abnormal metabolic fate of nitric oxide in Type I diabetes mellitus
Milsom, A. B., Jones, C., Goodfellow, J., Frenneaux, M. P., Peters, J. R., & James, P. E. (2002) · Diabetologia · doi:10.1007/s00125-002-0956-9 · Cited by 75
Efficacy and age-related effects of nitric oxide-releasing aspirin on experimental restenosis
Claudio Napoli, A., Aldini, G., Wallace, J. L., de Nigris, F., Maffei, R., Abete, P., Bonaduce, D., Condorelli, G., Rengo, F., Sica, V., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.022639399 · Cited by 75
Romeo, A. A., Capobianco, J. A., & English, A. M. (2003) · Journal of the American Chemical Society · doi:10.1021/ja0289752 · Cited by 49
Evaluation of systemic blood NO dynamics by EPR spectroscopy: HbNO as an endogenous index of NO
Kirima, K., Tsuchiya, K., Séi, H., Hasegawa, T., Shikishima, M., Motobayashi, Y., Morita, K., Yoshizumi, M., & Tamaki, T. (2003) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01010.2002 · Cited by 41
Massy, Z. A., Fumeron, C., Borderie, D., Tuppin, P., Nguyen‐Khoa, T., Benoit, M., Jacquot, C., Buisson, C., Drüeke, T. B., Ekindjian, O. G., et al. (2004) · Journal of the American Society of Nephrology · doi:10.1097/01.asn.0000106716.22153.bb · Cited by 38
Inhaled [13N]nitric oxide: A positron emission tomography (PET) study
McCarthy, T. J., Dence, C. S., Holmberg, S. W., Markham, J., Schuster, D. P., & Welch, M. J. (1996) · Nuclear Medicine and Biology · doi:10.1016/0969-8051(96)00072-8 · Cited by 11
Reply to "NO adducts in mammalian red blood cells: too much or too little?"
Stamler, J. S., Hess, D. T., & Singel, D. J. (2003) · Nature Medicine · doi:10.1038/nm0503-482 · Cited by 10
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Sorted by citations
Protein S-nitrosylation: Purview and parameters
Hess, D. T., Matsumoto, A., Kim, S.-O., Marshall, H. E., & Stamler, J. S. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1569 · Cited by 2,153
“Protein S -nitrosothiol: turnover and homeostasis Analysis of the S–N-bond dissociation energies of many RSNOs (where R is the organic moiety that bears the SNO) has shown that (unimolecular) homolytic decomposition (that is, the scission of the S–N bond to yield the NO• and thiyl radicals) is typically precluded, and…”
BackgroundSelf-citationHuman serum albumin: From bench to bedside
Fanali, G., di Masi, A., Trezza, V., Marino, M., Fasano, M., & Ascenzi, P. (2011) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2011.12.002 · Cited by 2,008
Methods to detect nitric oxide and its metabolites in biological samples
Bryan, N. S., & Grisham, M. B. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.04.026 · Cited by 1,005
“However, it along with all methodologies has its limitations and remains a topic of intense discussion and controversy [77,89-92] specifically regarding its efficacy and specificity for detecting and quantifying RSNOs in hemoglobin and red cells.”
BackgroundTsikas, D. (2006) · Journal of Chromatography B · doi:10.1016/j.jchromb.2006.07.054 · Cited by 897
Vascular nitric oxide: Beyond eNOS
Zhao, Y., Vanhoutte, P. M., & Leung, S. W. S. (2015) · Journal of Pharmacological Sciences · doi:10.1016/j.jphs.2015.09.002 · Cited by 875
Metadata
- Authors
- Stamler, J. S.
- Affiliations
- Howard Hughes Medical Institute (US)
- Corresponding author
- Stamler, Jonathan S.
- ORCID
- Stamler, Jonathan S.
- Venue
- Circulation Research
- Published
- 2004-03-05
- Volume
- 94
- Issue
- 4
- Pages
- 414-417
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- OpenAlex
- W2164531124
- Cited by
- 170
- References
- 32
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 3 · 2023: 8 · 2022: 2 · 2021: 3 · 2020: 2 · 2019: 4 · 2018: 4 · 2017: 5 · 2016: 3 · 2015: 6 · 2014: 5 · 2013: 4 · 2012: 9
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Circulation Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Sulfur Compounds in Biology
- Keywords
- S-nitrosothiols, blood, nitric oxide, nitrosation, hemoglobin, nitrite
- MeSH terms
- Forecasting, Hemoglobins, Humans, Models, Biological, Nitric Oxide, Nitroso Compounds, Oxidation-Reduction, Oxygen, Reference Standards, Serum Albumin, Bovine, Sulfhydryl Compounds, Superoxides, Vasodilation, S-Nitrosoglutathione
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