The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Atrial septal aneurysm and patent foramen ovale as risk factors for cryptogenic stroke in patients less than 55 years of age. A study using transesophageal echocardiography.
Abstract
An association between atrial septal aneurysm and embolic events has been suggested. Atrial septal aneurysm has been shown to be associated with patent foramen ovale and, in some reports, with mitral valve prolapse. These two latter cardiac disorders have been identified as potential risk factors for ischemic stroke. The aim of this prospective study was to assess the role of atrial septal aneurysm as an independent risk factor for stroke, especially for cryptogenic stroke. We studied the prevalence of atrial septal aneurysm, patent foramen ovale, and mitral valve prolapse in 100 consecutive patients < 55 years of age with ischemic stroke who underwent extensive etiological investigations. We compared these results with those in a control group of 50 consecutive patients. The diagnosis of atrial septal aneurysm and patent foramen ovale relied on transesophageal echocardiography with a contrast study and that of mitral valve prolapse, on two-dimensional transthoracic echocardiography. Stepwise logistic regression analysis showed that atrial septal aneurysm (odds ratio, 4.3; 95% confidence interval, 1.3 to 14.6; P = .01) and patent foramen ovale (odds ratio, 3.9; 95% confidence interval, 1.5 to 10; P = .003) but not mitral valve prolapse were significantly associated with the diagnosis of cryptogenic stroke. The stroke odds of a patient with both atrial septal aneurysm and patent foramen ovale were 33.3 times (95% confidence interval, 4.1 to 270) the stroke odds of a patient with neither of these cardiac disorders. For a patient with atrial septal aneurysm of > 10-mm excursion, the stroke odds were approximately 8 times the stroke odds of a patient with atrial septal aneurysm of < 10 mm. This study shows that atrial septal aneurysm and patent foramen ovale are both significantly associated with cryptogenic stroke and that their association has a marked synergistic effect. Atrial septal aneurysms of > 10-mm excursion are associated with a higher risk of stroke.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Prevalence of Patent Foramen Ovale in Patients with Stroke
Lechat, P., Mas, J. L., Lascault, G., Loron, P., Theard, M., Klimczac, M., Drobinski, G., Thomas, D., & Grosgogeat, Y. (1988) · New England Journal of Medicine · doi:10.1056/nejm198805053181802 · Cited by 1,657
Self-citationPATENT FORAMEN OVALE IN YOUNG STROKE PATIENTS
Webster, M. W. I., Smith, H. J., Sharpe, D. N., Chancellor, A. M., Swift, D. L., Bass, N. M., & Glasgow, G. L. (1988) · The Lancet · doi:10.1016/s0140-6736(88)92944-3 · Cited by 823
Patent Foramen Ovale as a Risk Factor for Cryptogenic Stroke
Di Tullio, M., Sacco, R. L., Gopal, A., Mohr, J. P., & Homma, S. (1992) · Annals of Internal Medicine · doi:10.7326/0003-4819-117-6-461 · Cited by 600
Pearson, A. C., Labovitz, A. J., Tatineni, S., & Gomez, C. R. (1991) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(91)90705-e · Cited by 570
Atrial septal aneurysm and stroke: A transesophageal echocardiographic study
Pearson, A. C., Nagelhout, D. A., Castelló, R., Gomez, C., & Labovitz, A. J. (1991) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(91)90539-l · Cited by 394
Further Evidence Relating Mitral-Valve Prolapse to Cerebral Ischemic Events
Barnett, H. J. M., Boughner, D. R., Taylor, D. W., Cooper, P. E., Kostuk, W. J., & Nichol, P. M. (1980) · New England Journal of Medicine · doi:10.1056/nejm198001173020303 · Cited by 346
Levine, R. A., Stathogiannis, E., Newell, J. B., Harrigan, P., & Weyman, A. E. (1988) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(98)90059-6 · Cited by 315
Schneider, B., Hanrath, P., Vogel, P. M., & Meinertz, T. (1990) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(10)80354-7 · Cited by 203
Cardiogenic embolism to the brain
Hart, R. G. (1992) · The Lancet · doi:10.1016/0140-6736(92)90873-2 · Cited by 171
Cited by
Kernan, W. N., Ovbiagele, B., Black, H. R., Bravata, D. M., Chimowitz, M. I., Ezekowitz, M. D., Fang, M. C., Fisher, M., Furie, K. L., Heck, D. V., et al. (2014) · Stroke · doi:10.1161/str.0000000000000024 · Cited by 5,170
Sacco, R. L., Adams, R., Albers, G., Alberts, M. J., Benavente, O., Furie, K., Goldstein, L. B., Gorelick, P., Halperin, J., Harbaugh, R., et al. (2006) · Stroke · doi:10.1161/01.str.0000199147.30016.74 · Cited by 1,873
Mas, J.-L., Arquizan, C., Lamy, C., Zuber, M., Cabanes, L., Derumeaux, G., & Coste, J. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa011503 · Cited by 1,361
Self-citationInteratrial septal abnormalities and stroke: A meta-analysis of case-control studies
Overell, J. R., Bone, I., & Lees, K. R. (2000) · Neurology · doi:10.1212/wnl.55.8.1172 · Cited by 936
Sloan, M. A., Alexandrov, A. V., Tegeler, C. H., Spencer, M. P., Caplan, L. R., Feldmann, E., Wechsler, L. R., Newell, D. W., Gomez, C. R., Babikian, V. L., et al. (2004) · Neurology · doi:10.1212/wnl.62.9.1468 · Cited by 517
Metadata
- Authors
- Cabanes, L., Mas, J. L., Cohen, A., Amarenco, P., Cabanes, P. A., Oubary, P., Chedru, F., Guérin, F., Bousser, M. G., & de Recondo, J.
- Venue
- Stroke
- Published
- 1993-12
- Volume
- 24
- Issue
- 12
- Pages
- 1865-1873
- ISSN
- 0039-2499 (ISSN-L)
- 1524-4628
- OpenAlex
- W2010050468
- Cited by
- 572
- References
- 9
- FWCI
- 6.53
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Atrial septal aneurysm and patent foramen ovale as risk factors for cryptogenic stroke in patients less than 55 years of age. A study using transesophageal echocardiography. https://app.cochat.ai/papers/10.1161/01.str.24.12.1865
- The paper
- Cabanes, L., Mas, J. L., Cohen, A., Amarenco, P., Cabanes, P. A., Oubary, P., Chedru, F., Guérin, F., Bousser, M. G., & de Recondo, J. (1993). Atrial septal aneurysm and patent foramen ovale as risk factors for cryptogenic stroke in patients less than 55 years of age. A study using transesophageal echocardiography. Stroke. https://doi.org/10.1161/01.str.24.12.1865
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
