Plasminogen Activator Inhibitor-1 Is a Marker and a Mediator of Senescence

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PAI-1–regulated extracellular proteolysis governs senescence and survival in <i>Klotho</i> mice

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Age-Dependent Spontaneous Coronary Arterial Thrombosis in Transgenic Mice That Express a Stable Form of Human Plasminogen Activator Inhibitor-1

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Plasminogen activator inhibitor 1—insulin-like growth factor binding protein 3 cascade regulates stress-induced senescence

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Stress-induced spine loss in the medial amygdala is mediated by tissue-plasminogen activator

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Plasminogen Activator Inhibitor-1 Antagonist TM5441 Attenuates N ω -Nitro- l -Arginine Methyl Ester–Induced Hypertension and Vascular Senescence

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Senescence-Dependent Regulation of Type 1 Plasminogen Activator Inhibitor in Human Vascular Endothelial Cells

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Nutritionally Induced Obesity Is Attenuated in Transgenic Mice Overexpressing Plasminogen Activator Inhibitor-1

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A small molecule inhibitor of PAI-1 protects against doxorubicin-induced cellular senescence

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Erratum: Variable telomere length across post-mortem human brain regions and specific reduction in the hippocampus of major depressive disorder

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NH4Cl Treatment Prevents Tissue Calcification in Klotho Deficiency

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Endothelium-specific SIRT1 overexpression inhibits hyperglycemia-induced upregulation of vascular cell senescence

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Transforming Growth Factor-β Requires Its Target Plasminogen Activator Inhibitor-1 for Cytostatic Activity

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Truncated Plasminogen Activator Inhibitor-1 Protein Protects From Pulmonary Fibrosis Mediated by Irradiation in a Murine Model

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Diverse Gene Sequences Are Overexpressed in Werner Syndrome Fibroblasts Undergoing Premature Replicative Senescence

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Is plasminogen activator inhibitor‐1 a physiological bottleneck bridging major depressive disorder and cardiovascular disease?

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TGF-β Signaling in Cellular Senescence and Aging-Related Pathology

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A Narrative Review on Plasminogen Activator Inhibitor-1 and Its (Patho)Physiological Role: To Target or Not to Target?

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Thrombotic Regulation From the Endothelial Cell Perspectives

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Reduced subcutaneous adipogenesis in human hypertrophic obesity is linked to senescent precursor cells

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Transcriptional heterogeneity of fibroblasts is a hallmark of the aging heart

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Targeting PAI-1 in Cardiovascular Disease: Structural Insights Into PAI-1 Functionality and Inhibition

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PAI-1 Regulation of TGF-β1–induced Alveolar Type II Cell Senescence, SASP Secretion, and SASP-mediated Activation of Alveolar Macrophages

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Copper deficiency may be a leading cause of ischaemic heart disease

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A Serpin With a Finger in Many PAIs: PAI-1's Central Function in Thromboinflammation and Cardiovascular Disease

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The TGF-β1/p53/PAI-1 Signaling Axis in Vascular Senescence: Role of Caveolin-1

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COVID-19 and Crosstalk With the Hallmarks of Aging

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PAI-1, the Plasminogen System, and Skeletal Muscle

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Patients with systemic lupus erythematosus face a high risk of cardiovascular disease: A systematic review and Meta-analysis

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Targets for protection and mitigation of radiation injury

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Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease

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Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression

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Stress-induced RNA–chromatin interactions promote endothelial dysfunction

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Drug Targeting of Plasminogen Activator Inhibitor-1 Inhibits Metabolic Dysfunction and Atherosclerosis in a Murine Model of Metabolic Syndrome

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The uPA/uPAR System Orchestrates the Inflammatory Response, Vascular Homeostasis, and Immune System in Fibrosis Progression

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The Role of Fibrinolytic Regulators in Vascular Dysfunction of Systemic Sclerosis

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Vascular Endothelial Senescence: Pathobiological Insights, Emerging Long Noncoding RNA Targets, Challenges and Therapeutic Opportunities

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A signaling pathway map of plasminogen activator inhibitor-1 (PAI-1/SERPINE-1): a review of an innovative frontier in molecular aging and cellular senescence

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Inhibition of PAI (Plasminogen Activator Inhibitor)-1 Improves Brain Collateral Perfusion and Injury After Acute Ischemic Stroke in Aged Hypertensive Rats

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Unveiling E2F4, TEAD1 and AP-1 as regulatory transcription factors of the replicative senescence program by multi-omics analysis

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