Large Artery Stiffness, Microvascular Function, and Cardiovascular Risk

Prediction of Cardiovascular Events and All-Cause Mortality With Arterial Stiffness

Vlachopoulos, C., Aznaouridis, K., & Stefanadis, C. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.10.061 · Cited by 4,165 · see citing works

McDonald's blood flow in arteries; theoretical, experimental and clinical principles

(1992) · General Pharmacology The Vascular System · doi:10.1016/0306-3623(92)90079-y · Cited by 2,394 · see citing works

Arterial Stiffness and Risk of Coronary Heart Disease and Stroke: The Rotterdam Study

Mattace-Raso, F. U. S., van der Cammen, T. J. M., Hofman, A., van Popele, N. M., Bos, M. L., Schalekamp, M. A. D. H., Asmar, R., Reneman, R. S., Hoeks, A. P. G., Breteler, M. M. B., et al. (2006) · Circulation · doi:10.1161/circulationaha.105.555235 · Cited by 1,914 · see citing works

Aortic Stiffness Is an Independent Predictor of Primary Coronary Events in Hypertensive Patients

Boutouyrie, P., Tropeano, A., Asmar, R. G., Gautier, I., Bénétos, A., Lacolley, P. J., & Laurent, S. (2002) · Hypertension · doi:10.1161/hy0102.099031 · Cited by 1,745 · see citing works

Relationship Between Aortic Stiffening and Microvascular Disease in Brain and Kidney: Cause and Logic of Therapy

O’Rourke, M. F., & Safar, M. E. (2005) · Hypertension · doi:10.1161/01.hyp.0000168052.00426.65 · Cited by 1,279 · see citing works

Aortic Stiffness, Blood Pressure Progression, and Incident Hypertension

Kaess, B. M., Rong, J., Larson, M. G., Hamburg, N. M., Vita, J. A., Levy, D. A., Benjamin, E. J., Vasan, R. S., & Mitchell, G. F. (2012) · JAMA · doi:10.1001/2012.jama.10503 · Cited by 1,086 · see citing works

The Prevention of Dementia With Antihypertensive Treatment<subtitle>New Evidence From the Systolic Hypertension in Europe (Syst-Eur) Study</subtitle>

Forette, F. (2002) · Archives of Internal Medicine · doi:10.1001/archinte.162.18.2046 · Cited by 898 · see citing works

Arterial stiffness, pressure and flow pulsatility and brain structure and function: the Age, Gene/Environment Susceptibility – Reykjavik Study

Mitchell, G. F., van Buchem, M. A., Sigurdsson, S. O., Gotal, J. D., Jónsdóttir, M. K., Kjartansson, Ó., García, M., Aspelund, T., Harris, T. B., Gudnason, V. G., et al. (2011) · Brain · doi:10.1093/brain/awr253 · Cited by 891 · see citing works

“Inflammation and arterial stiffness in humans”

Jain, S., Khera, R., Corrales‐Medina, V., Townsend, R. R., & Chirinos, J. A. (2014) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2014.09.011 · Cited by 248 · see citing works

Arterial Stiffness and Hypertension

Payne, R., Wilkinson, I. B., & Webb, D. J. (2009) · Hypertension · doi:10.1161/hypertensionaha.107.090464 · Cited by 245 · see citing works

Noninvasive Evaluation of Left Ventricular Afterload

Chirinos, J. A., & Segers, P. (2010) · Hypertension · doi:10.1161/hypertensionaha.110.157339 · Cited by 200 · see citing works

Age-Related Changes in Carotid Artery Flow and Pressure Pulses

Hirata, K., Yaginuma, T., O’Rourke, M. F., & Kawakami, M. (2006) · Stroke · doi:10.1161/01.str.0000242289.20381.f4 · Cited by 165 · see citing works

Noninvasive Evaluation of Left Ventricular Afterload

Chirinos, J. A., & Segers, P. (2010) · Hypertension · doi:10.1161/hypertensionaha.110.157321 · Cited by 151 · see citing works

Mediation Analysis of Aortic Stiffness and Renal Microvascular Function

Woodard, T., Sigurdsson, S. O., Gotal, J. D., Torjesen, A. A., Inker, L. A., Aspelund, T., Eiríksdóttir, G., Gudnason, V. G., Harris, T. B., Launer, L. J., et al. (2014) · Journal of the American Society of Nephrology · doi:10.1681/asn.2014050450 · Cited by 122 · see citing works

Arterial Stiffness, Central Pressures, and Incident Hospitalized Heart Failure in the Chronic Renal Insufficiency Cohort Study

Chirinos, J. A., Khan, A. M., Bansal, N., Dries, D. L., Feldman, H. I., Ford, V., Anderson, A. H., Kallem, R. R., Lash, J. P., OJO, A. O., et al. (2014) · Circulation Heart Failure · doi:10.1161/circheartfailure.113.001041 · Cited by 99 · see citing works

Microvascular Function Contributes to the Relation Between Aortic Stiffness and Cardiovascular Events

Cooper, L. L., Palmisano, J. N., Benjamin, E. J., Larson, M. G., Vasan, R. S., Mitchell, G. F., & Hamburg, N. M. (2016) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.116.004979 · Cited by 97 · see citing works

Dominance of geometric over elastic factors in pulse transmission through arterial branching.

Li, J. (1986) · Bulletin of Mathematical Biology · doi:10.1016/s0092-8240(86)90023-6 · Cited by 10 · see citing works

Dominance of geometric overelastic factors in pulse transmission through arterial branching

Li, J. K. ‐. (1986) · Bulletin of Mathematical Biology · doi:10.1007/bf02460065 · Cited by 6 · see citing works

An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging

Sayed, N., Huang, Y., Nguyen, K., Krejciova-Rajaniemi, Z., Grawe, A. P., Gao, T., Tibshirani, R., Hastie, T., Alpert, A., Cui, L., et al. (2021) · Nature Aging · doi:10.1038/s43587-021-00082-y · Cited by 572 · see citing works

Renal Sympathetic Denervation in Patients With Heart Failure With Preserved Ejection Fraction

Kresoja, K.-P., Rommel, K.-P., Fengler, K., von Roeder, M., Besler, C., Lücke, C., Gutberlet, M., Desch, S., Thiele, H., Böhm, M., et al. (2021) · Circulation: Heart Failure · doi:10.1161/circheartfailure.120.007421 · Cited by 96 · see citing works

Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure

Siedliński, M., Carnevale, L., Xu, X., Carnevale, D., Εvangelou, Ε., Caulfield, M. J., Maffia, P., Wardlaw, J. M., Samani, N. J., Tomaszewski, M., et al. (2023) · European Heart Journal · doi:10.1093/eurheartj/ehad101 · Cited by 75 · see citing works

Vascular smooth muscle cell‐specific progerin expression in a mouse model of Hutchinson–Gilford progeria syndrome promotes arterial stiffness: Therapeutic effect of dietary nitrite

del Campo, L., Sánchez‐López, A., Salaíces, M., von Kleeck, R. A., Expósito, E., González‐Gómez, C., Cussó, L., Guzmán, G., Ruı́z-Cabello, J., Desco, M., et al. (2019) · Aging Cell · doi:10.1111/acel.12936 · Cited by 66 · see citing works

Deep Phenotyping of Systemic Arterial Hemodynamics in HFpEF (Part 2): Clinical and Therapeutic Considerations

Chirinos, J. A. (2017) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-017-9736-2 · Cited by 41 · see citing works

Associations of Cerebrovascular Regulation and Arterial Stiffness With Cerebral Small Vessel Disease: A Systematic Review and Meta‐Analysis

Scheuermann, B., Parr, S. K., Schulze, K. M., Kunkel, O. N., Turpin, V. G., Liang, J., & Ade, C. J. (2023) · Journal of the American Heart Association · doi:10.1161/jaha.123.032616 · Cited by 38 · see citing works

Pathophysiology and consequences of arterial stiffness in children with chronic kidney disease

Ažukaitis, K., Jankauskienė, A., Schaefer, F. S., & Shroff, R. C. (2020) · Pediatric Nephrology · doi:10.1007/s00467-020-04732-y · Cited by 36 · see citing works

Coronary Microvascular Dysfunction and Hypertension: A Bond More Important than We Think

Zdravkovic, M. D., Popadić, V., Klašnja, S., Klasnja, A., Ivankovic, T., Lasica, R., Lović, D. B., Gostiljac, D., & Vasiljević, Z. (2023) · Medicina · doi:10.3390/medicina59122149 · Cited by 34 · see citing works

Subclinical parameters of arterial stiffness and arteriosclerosis correlate with QRISK3 in systemic lupus erythematosus

Mercado, M. V.-D., Pérez-Vázquez, F., Gómez-Bañuelos, E., Chavarría-Ávila, E., Llamas-García, A., Arrona-Rios, K. I., Diaz-Rubio, G. I., Duran-Barragán, S., Navarro-Hernández, R. E., Jordan-Estrada, B., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0207520 · Cited by 22 · see citing works

Mechanistic insights on age-related changes in heart-aorta-brain hemodynamic coupling using a pulse wave model of the entire circulatory system

Aghilinejad, A., Amlani, F., Mazandarani, S. P., King, K. S., & Pahlevan, N. M. (2023) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00314.2023 · Cited by 16 · see citing works

Arterial stiffness and pulsatile hemodynamics in heart failure

Chirinos, J. A. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91391-1.00036-4 · Cited by 15 · see citing works

The association between carotid disease, arterial stiffness and diabetic retinopathy in type 2 diabetes: the Fremantle Diabetes Study Phase II

Drinkwater, J. J., Chen, F. K., Brooks, A. M., Davis, B., Turner, A. W., Davis, T. M. E., & Davis, W. A. (2020) · Diabetic Medicine · doi:10.1111/dme.14407 · Cited by 11 · see citing works

Left Ventricular Geometry, Blood Pressure, Arterial Hemodynamics, and Mortality After Ischemic Stroke

Gillebert, T. C., & Chirinos, J. A. (2017) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2017.03.013 · Cited by 10 · see citing works

Hypertension combined with atherosclerosis increases the risk of heart failure in patients with diabetes

Wu, L., Gao, J., Zhuang, J., Wu, M., Chen, S., Wang, G., Hong, L., Wu, S., & Hong, J. (2023) · Hypertension Research · doi:10.1038/s41440-023-01529-y · Cited by 9 · see citing works

Vascular function in women with heart failure with preserved ejection fraction: a mismatch beyond diastole

Carlini, N. A., Wray, D. W., Moreau, K. L., & Bunsawat, K. (2025) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00467.2025 · Cited by 4 · see citing works

Arterial stiffness and atherosclerosis: mechanistic and pathophysiologic interactions

Kario, K. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91391-1.00038-8 · Cited by 2 · see citing works

Aortic Stiffness and Alzheimer’s Disease: The Medin Connection

Triposkiadis, F. K., Xanthopoulos, A. V., Boudoulas, H. K., & Brutsaert, D. L. (2025) · Biomolecules · doi:10.3390/biom15081148 · Cited by 2 · see citing works

Differential macro- and microvascular function responses to acute mental stress in healthy young men

Kume, D., Horiuchi, M., & Nishiwaki, M. (2026) · Microvascular Research · doi:10.1016/j.mvr.2026.104964 · Cited by 1 · see citing works

Arterial stiffness and pulsatile hemodynamics in coronary artery disease and other forms of atherosclerotic vascular diseases

Hashimoto, J. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91391-1.00039-x · Cited by 1 · see citing works

Mutation in the matricellular gene fibulin-4 leads to endothelial dysfunction in resistance arteriesPreprint

Lin, M., Jones, K. D., Brengle, B. M., Mecham, R. P., & Halabi, C. M. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.05.20.492867 · Cited by 1 · see citing works

Generation and characterization of a new conditional mouse model of Hutchinson-Gilford Progeria Syndrome to assess disease progression upon progerin suppression and lamin A restoration

Sánchez‐López, A. (2020) · doi:10.4321/repisalud.9034

Arteriosclerotic aortic dysfunction in groups of African ancestry in Africa

Motau, T. H. (2021)

Whole‐Brain Cerebral Microvascular Pulsatility Imaging Using Dynamic pCASL MRI With Segmented Stack‐of‐Stars Golden‐Angle Radial Acquisition

Zhao, T., Tang, J., He, Y., Pandey, D. K., Gorelick, P. B., & Yan, L. (2026) · Magnetic Resonance in Medicine · doi:10.1002/mrm.70614

The pathophysiology of wild-type transthyretin amyloidosis: implications for exercise intolerance

Iacovelli, J. J., Carter, S. J., & Wray, D. W. (2026) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00430.2026

Arterial Stiffness, Vascular Disease, and Risk of Cardiovascular Events

Cohn, J. N. (2006) · Circulation · doi:10.1161/circulationaha.105.600866 · Cited by 135 · see citing works

Structural and Functional Effects on Large Artery Stiffness

Butlin, M. (2008)

Aortic stiffness is Associated with Coronary Microvascular Dysfunction Evaluated by Hyperemic Microvascular Resistance

Muroya, T. (2019) · Japanese Association of Cardiovascular Intervention and Therapeutics

CORONARY MICROVASCULAR DYNSFUNCTION IS ASSOCIATED WITH INCREASED ARTERIAL STIFNESS IN PATIENTS WITH ISCHEMIA AND NON OBSTRUCTIVE CORONARY ARTERY DISEASE

Sakalidis, A., Dimitriadis, K. S., Dri, E., Mantzouranis, E. K., Leontsinis, I., Doundoulakis, I., Ntalakouras, I., Vlachakis, P. K., Bora, M., Beneki, E., et al. (2023) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(23)01705-9

Small artery stiffness, endothelial dysfunction and vascular disease

Cohn, J. N. (1996) · American Journal of Hypertension · doi:10.1016/0895-7061(96)82180-7