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Cited by 837

The DOI matches its Crossref record; 221 of the 221 references it cites were found in a registry or an index.

Heart Failure With Preserved Ejection Fraction In Perspective

Open access
Pfeffer, Marc A., Shah, Amil M., Borlaug, Barry A.·2019·Circulation Research

Abstract

Approximately half of the patients with signs and symptoms of heart failure have a left ventricular ejection fraction that is not markedly abnormal. Despite the historically initial surprise, heightened risks for heart failure specific major adverse events occur across the broad range of ejection fraction, including normal. The recognition of the magnitude of the problem of heart failure with preserved ejection fraction in the past 20 years has spurred an explosion of clinical investigation and growing intensity of informative outcome trials. This article addresses the historic development of this component of the heart failure syndrome, including the epidemiology, pathophysiology, and existing and planned therapeutic studies. Looking forward, more specific phenotyping and even genotyping of subpopulations should lead to improvements in outcomes from future trials.

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Registry

Crossref · 10.1161/circresaha.119.313572

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Metadata

Authors
Pfeffer, M. A., Shah, A. M., & Borlaug, B. A.
Venue
Circulation Research
Published
2019-05-24
Volume
124
Issue
11
Pages
1598-1617
ISSN
  • 0009-7330 (ISSN-L)
  • 1524-4571
OpenAlex
W2945334580
Cited by
837
References
221
FWCI
62.60
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Heart Failure With Preserved Ejection Fraction In Perspective. https://app.cochat.ai/papers/10.1161/circresaha.119.313572
The paper
Pfeffer, M. A., Shah, A. M., & Borlaug, B. A. (2019). Heart Failure With Preserved Ejection Fraction In Perspective. Circulation Research. https://doi.org/10.1161/circresaha.119.313572

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.