Reduced Mitochondrial Oxidative Capacity and Increased Mitochondrial Uncoupling Impair Myocardial Energetics in Obesity
Boudina, Sihem, Sena, Sandra, O’Neill, Brian T., Tathireddy, Prakash, Young, Martin E., Abel, E. Dale·2005·Circulation
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- Myocardial Metabolism in Diabetic Cardiomyopathy: Potential Therapeutic TargetsMiranda M. Y. Sung, Shereen M. Hamza, Jason R.B. Dyck · 2015 · Antioxidants and Redox Signaling
- Perturbations in myocardial perfusion and oxygen balance in swine with multiple risk factors: a novel model of ischemia and no obstructive coronary artery diseaseJens van de Wouw, Oana Sorop, Ruben W. A. van Drie, Richard W. B. van Duin, Isabella Nguyen, Jaap A. Joles, Marianne Christina Verhaar, Daphne Merkus, Dirk Jan Duncker · 2020 · Basic Research in Cardiology
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- Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolismKenneth D’Souza, Carine Nzirorera, Andrew M. Cowie, Geena P. Varghese, Purvi C. Trivedi, Thomas Oliver Eichmann, Dipsikha Biswas, Mohamed Touaibia, Andrew J. Morris, Vassilis Aidinis et al. · 2018 · Journal of Lipid Research
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- GLUT1 deficiency in cardiomyocytes does not accelerate the transition from compensated hypertrophy to heart failureRenata Oliveira Pereira, Adam R. Wende, Curtis D. Olsen, Jamie E. Soto, Tenley A. Rawlings, Yi Zhu, Christian Riehle, E. Dale Abel · 2014 · Journal of Molecular and Cellular Cardiology
- Resveratrol and exerciseSaltuk Buğra Baltacı, Rasim Moğulkoç, Abdülkerim Kasım Baltacı · 2016 · Biomedical Reports
- Type 2 diabetes, mitochondrial biology and the heartMichael N. Sack · 2009 · Journal of Molecular and Cellular Cardiology
- Platelets of type 2 diabetic patients are characterized by high ATP content and low mitochondrial membrane potentialJianmin Ran, Xinmin Guo, Qingmei Li, Guangzhong Mei, Lao Gancheng · 2009 · Platelets
- Maintaining PGC‐1α expression following pressure overload‐induced cardiac hypertrophy preserves angiogenesis but not contractile or mitochondrial functionRenata Oliveira Pereira, Adam R. Wende, Ashley Crum, Douglas Hunter, Curtis D. Olsen, Tenley A. Rawlings, Christian Riehle, Walter F. Ward, E. Dale Abel · 2014 · The FASEB Journal
- Lipoamide or lipoic acid stimulates mitochondrial biogenesis in 3T3-L1 adipocytes via the endothelial NO synthase–cGMP–protein kinase G signalling pathwayShen, Weili, Hao, Jiejie, Feng, Zhihui, Tian, Chuan, Chen, Weijun, Packer, Lester, Shi, Xianglin, Zang, Weijin, Liu, Jiankang · 2011 · British Journal of Pharmacology
- Mitofusin-2 Regulates Platelet Mitochondria and FunctionShancy Petsel Jacob, Yasuhiro Kosaka, Seema Bhatlekar, Frederik Denorme, Haley Benzon, Alexandra Moody, Victoria Moody, Emilia A Tugolukova, Grayson Hull, Nina Y. Kishimoto et al. · 2023 · Circulation Research
- Perspectives and Potential Applications of Mitochondria‐Targeted Antioxidants in Cardiometabolic Diseases and Type 2 DiabetesMilagros Rocha, Nadezda Apostolova, José Raúl Herance, Susana Rovira‐Llopis, Antonio Hernández‐Mijares, Víctor M. Víctor · 2013 · Medicinal Research Reviews
- Nutrient availability links mitochondria, apoptosis, and obesityFrancesca Pintus, Giovanni Floris, Alessandro Rufini · 2012 · Aging
- Influence of cardiometabolic comorbidities on myocardial function, infarction, and cardioprotection: Role of cardiac redox signalingIoanna Andreadou, Andreas Daiber, Gary F. Baxter, Maria Felice Brizzi, Fabio Di Lisa, Nina Kaludercic, Antigone Lazou, Zoltán V. Varga, Coert Jozef Zuurbier, Rainer Schulz et al. · 2021 · Free Radical Biology and Medicine
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