The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Frail Patients Are at Increased Risk for Mortality and Prolonged Institutional Care After Cardiac Surgery
Abstract
Background— Frailty is an emerging concept in medicine yet to be explored as a risk factor in cardiac surgery. Where elderly patients are increasingly referred for cardiac surgery, the prevalence of a frail group among these is also on the rise. We assessed frailty as a risk factor for adverse outcomes after cardiac surgery. Methods and Results— Functional measures of frailty and clinical data were collected prospectively for all cardiac surgery patients at a single center. Frailty was defined as any impairment in activities of daily living (Katz index), ambulation, or a documented history of dementia. Of 3826 patients, 157 (4.1%) were frail. Frail patients were older, were more likely to be female, and had risk factors for adverse surgical outcomes. By logistic regression, frailty was an independent predictor of in-hospital mortality (odds ratio 1.8, 95% CI 1.1 to 3.0), as well as institutional discharge (odds ratio 6.3, 95% CI 4.2 to 9.4). Frailty was an independent predictor of reduced midterm survival (hazard ratio 1.5, 95% CI 1.1 to 2.2). Conclusions— Frailty is a risk for postoperative complications and an independent predictor of in-hospital mortality, institutional discharge, and reduced midterm survival. Frailty screening improves risk assessment in cardiac surgery patients and may identify a subgroup of patients who may benefit from innovative processes of care.
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Cites
Frailty in Older Adults: Evidence for a Phenotype
Fried, L. P., Tangen, C. M., Walston, J., Newman, A. B., Hirsch, C., Gottdiener, J., Seeman, T., Tracy, R., Kop, W. J., Burke, G., et al. (2001) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/56.3.m146 · Cited by 24,907
Validity and reliability of the Edmonton Frail Scale
Rolfson, D. B., Majumdar, S. R., Tsuyuki, R. T., Tahir, A., & Rockwood, K. (2006) · Age and Ageing · doi:10.1093/ageing/afl041 · Cited by 1,643
Nonparametric estimates of standard error: The jackknife, the bootstrap and other methods
EFRON, B. (1981) · Biometrika · doi:10.1093/biomet/68.3.589 · Cited by 1,399
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Guidelines on the management of valvular heart disease (version 2012)
Authors/Task Force Members, Vahanian, A., Alfieri, O., Andreotti, F., Antunes, M. J., Barón-Esquivias, G., Baumgartner, H., Borger, M. A., Carrel, T. P., De Bonis, M., et al. (2012) · European Heart Journal · doi:10.1093/eurheartj/ehs109 · Cited by 3,559
2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease
Nishimura, R. A., Otto, C. M., Bonow, R. O., Carabello, B. A., Erwin, J. P., Guyton, R. A., O’Gara, P. T., Ruiz, C. E., Skubas, N. J., Sorajja, P., et al. (2014) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2014.02.536 · Cited by 3,523
Frailty Assessment in the Cardiovascular Care of Older Adults
Afilalo, J., Alexander, K. P., Mack, M. J., Maurer, M. S., Green, P., Allen, L. A., Popma, J. J., Ferrucci, L., & Forman, D. E. (2014) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.09.070 · Cited by 1,173
The impact of frailty on intensive care unit outcomes: a systematic review and meta-analysis
Muscedere, J., Waters, B., Varambally, A., Bagshaw, S. M., Boyd, J. G., Maslove, D., Sibley, S., & Rockwood, K. (2017) · Intensive Care Medicine · doi:10.1007/s00134-017-4867-0 · Cited by 827
Afilalo, J., Eisenberg, M. J., Morin, J.-F., Bergman, H., Monette, J., Noiseux, N., Perrault, L. P., Alexander, K. P., Langlois, Y., Dendukuri, N., et al. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.06.039 · Cited by 746
Metadata
- Authors
- Lee, D. H., Buth, K. J., Martin, B.-J., Yip, A. M., & Hirsch, G. M.
- Venue
- Circulation
- Published
- 2010-03-02
- Volume
- 121
- Issue
- 8
- Pages
- 973-978
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2104655786
- Cited by
- 680
- References
- 3
- FWCI
- 12.26
- Type
- journal article
- Language
- en
- Open access
- closed
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- Lee, D. H., Buth, K. J., Martin, B.-J., Yip, A. M., & Hirsch, G. M. (2010). Frail Patients Are at Increased Risk for Mortality and Prolonged Institutional Care After Cardiac Surgery. Circulation. https://doi.org/10.1161/circulationaha.108.841437
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
