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IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling system

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Induction of Cachexia in Mice by Systemically Administered Myostatin

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The Transforming Growth Factor-β Superfamily Member Growth-Differentiation Factor-15 Protects the Heart From Ischemia/Reperfusion Injury

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GDF15/MIC-1 Functions As a Protective and Antihypertrophic Factor Released From the Myocardium in Association With SMAD Protein Activation

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The role of natriuretic peptides in cardioprotection

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Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo

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TGF-β1 mediates the hypertrophic cardiomyocyte growth induced by angiotensin II

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Prognostic Value of Growth-Differentiation Factor-15 in Patients With Non–ST-Elevation Acute Coronary Syndrome

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Interleukin-33 Prevents Apoptosis and Improves Survival After Experimental Myocardial Infarction Through ST2 Signaling

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Regulation of cardiac growth and coronary angiogenesis by the Akt/PKB signaling pathwayPreprint

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MANF: A New Mesencephalic, Astrocyte-Derived Neurotrophic Factor with Selectivity for Dopaminergic Neurons

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TGF-β1 mediates the hypertrophic cardiomyocyte growth induced by angiotensin II

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Follistatin-like 1, a secreted muscle protein, promotes endothelial cell function and revascularization in ischemic tissue through a nitric-oxide synthase-dependent mechanism

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Intramyocardial Fibroblast Myocyte Communication

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Serial Measurement of Growth-Differentiation Factor-15 in Heart Failure

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Cell Communications in the Heart

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Interleukin 33 as a Mechanically Responsive Cytokine Secreted by Living Cells

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Role of Neuregulin-1/ErbB Signaling in Cardiovascular Physiology and Disease

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Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death

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Follistatin-like 1 is an Akt-regulated cardioprotective factor that is secreted by the heart

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Regulation of Muscle Mass by Follistatin and Activins

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Genetic deletion of myostatin from the heart prevents skeletal muscle atrophy in heart failure

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Growth Differentiation Factor 15 for Risk Stratification and Selection of an Invasive Treatment Strategy in Non–ST-Elevation Acute Coronary Syndrome

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Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction

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TNFα in myocardial ischemia/reperfusion, remodeling and heart failure

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Exogenously administered secreted frizzled related protein 2 (Sfrp2) reduces fibrosis and improves cardiac function in a rat model of myocardial infarction

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Mesencephalic Astrocyte-derived Neurotrophic Factor Protects the Heart from Ischemic Damage and Is Selectively Secreted upon Sarco/endoplasmic Reticulum Calcium Depletion

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Therapeutic impact of follistatin-like 1 on myocardial ischemic injury in preclinical models

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The Wnt modulator sFRP2 enhances mesenchymal stem cell engraftment, granulation tissue formation and myocardial repair

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Cardiac macrophage migration inhibitory factor inhibits JNK pathway activation and injury during ischemia/reperfusion

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Endothelium-Derived Neuregulin Protects the Heart Against Ischemic Injury

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Mesencephalic Astrocyte-Derived Neurotrophic Factor Is an Ischemia-Inducible Secreted Endoplasmic Reticulum Stress Response Protein in the Heart

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Impaired macrophage migration inhibitory factor-AMP-activated protein kinase activation and ischemic recovery in the senescent heart

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Arrhythmogenic Implications of Fibroblast-Myocyte Interactions

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Angiotensin II, Oxidative Stress and Skeletal Muscle Wasting

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Myostatin activation in patients with advanced heart failure and after mechanical unloading

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Impact of Exercise Training on Myostatin Expression in the Myocardium and Skeletal Muscle in a Chronic Heart Failure Model

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Cardiac myocyte follistatin-like 1 functions to attenuate hypertrophy following pressure overload

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Importance of Myocyte-Nonmyocyte Interactions in Cardiac Development and Disease

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An IL-1 Family Member Requires Caspase-1 Processing and Signals through the ST2 Receptor

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DIP2A Functions as a FSTL1 Receptor

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Secreted frizzled related protein 2 protects cells from apoptosis by blocking the effect of canonical Wnt3a

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Akt Signaling and Growth of the Heart

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Adjustment of the GRACE score by growth differentiation factor 15 enables a more accurate appreciation of risk in non-ST-elevation acute coronary syndrome

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Activin A and Follistatin-Like 3 Determine the Susceptibility of Heart to Ischemic Injury

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Growth-Differentiation Factor-15 for Long-Term Risk Prediction in Patients Stabilized After an Episode of Non–ST-Segment–Elevation Acute Coronary Syndrome

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Expression of Follistatin-Related Genes Is Altered in Heart Failure

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Cardioprotection Through S -Nitros(yl)ation of Macrophage Migration Inhibitory Factor

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Cardiac growth and angiogenesis coordinated by intertissue interactions

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Circulating Concentrations of Follistatin-Like 1 in Healthy Individuals and Patients with Acute Coronary Syndrome as Assessed by an Immunoluminometric Sandwich Assay

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DIP2 disco‐interacting protein 2 homolog A (Drosophila) is a candidate receptor for follistatin‐related protein/follistatin‐like 1 – analysis of their binding with TGF‐β superfamily proteins

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Follistatin-Like 1 in Chronic Systolic Heart Failure: A Marker of Left Ventricular Remodeling

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Functions for the cardiomyokine, MANF, in cardioprotection, hypertrophy and heart failure

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IL-33 Independently Induces Eosinophilic Pericarditis and Cardiac Dilation: ST2 Improves Cardiac Function

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A Secretion Trap Screen in Yeast Identifies Protease Inhibitor 16 as a Novel Antihypertrophic Protein Secreted From the Heart

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Identification of Follistatin-Like 1 by Expression Cloning as an Activator of the Growth Differentiation Factor 15 Gene and a Prognostic Biomarker in Acute Coronary Syndrome

Widera, C., Giannitsis, E., Kempf, T., Korf‐Klingebiel, M., Fiedler, B., Sharma, S. K., Katus, H. A., Asaumi, Y., Shimano, M., Walsh, K., et al. (2012) · Clinical Chemistry · doi:10.1373/clinchem.2012.182816 · Cited by 53 · see citing works

Microarray analysis of Akt1 activation in transgenic mouse hearts reveals transcript expression profiles associated with compensatory hypertrophy and failure

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Angiotensin II as candidate of cardiac cachexia

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Cardiac Myocyte-specific Ablation of Follistatin-like 3 Attenuates Stress-induced Myocardial Hypertrophy

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Mechanisms of physiological and pathological cardiac hypertrophy

Nakamura, M., & Sadoshima, J. (2018) · Nature Reviews Cardiology · doi:10.1038/s41569-018-0007-y · Cited by 1,662 · see citing works

Muscle–Organ Crosstalk: The Emerging Roles of Myokines

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Heart Failure in Type 2 Diabetes Mellitus

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Molecularly defined and spatially resolved cell atlas of the whole mouse brain

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GDF-15 as a Target and Biomarker for Diabetes and Cardiovascular Diseases: A Translational Prospective

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Inflammation – Cause or Consequence of Heart Failure or Both?

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Stress and Inflammation in Coronary Artery Disease: A Review Psychoneuroendocrineimmunology-Based

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Muscle as a “Mediator” of Systemic Metabolism

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Metabolism in cardiomyopathy: every substrate matters

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Inflammation and NLRP3 Inflammasome Activation Initiated in Response to Pressure Overload by Ca 2+ /Calmodulin-Dependent Protein Kinase II δ Signaling in Cardiomyocytes Are Essential for Adverse Cardiac Remodeling

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AMPK: energy sensor and survival mechanism in the ischemic heart

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Adipose tissue and its role in organ crosstalk

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The Heart as a Psychoneuroendocrine and Immunoregulatory Organ

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Quantitative Secretomics Reveals Extrinsic Signals Involved in Human Pluripotent Stem Cell Cardiomyogenesis

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SIRPα Mediates IGF1 Receptor in Cardiomyopathy Induced by Chronic Kidney Disease

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Molecular Mediators of the Cardiac Benefits of Exercise

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Autoantibodies Against β 1 ‐Adrenoceptor Exaggerated Ventricular Remodeling by Inhibiting CTRP9 Expression

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