Cited by 228Heart Rate Variability and Autonomic ControlPhysical Activity and HealthCardiovascular and exercise physiology

The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.

Physical Activity and Heart Rate Variability in Older Adults: The Cardiovascular Health Study

Open access

Soares-Miranda, Luisa, Sattelmair, Jacob, Chaves, Paulo, Duncan, Glen E., Siscovick, David S., Stein, Phyllis K., Mozaffarian, Dariush·2014·Circulation

DOI 10.1161/circulationaha.113.005361PMC PMC4038662

Open this paper in CoChat — free account

Abstract

BACKGROUND: Cardiac mortality and electrophysiological dysfunction both increase with age. Heart rate variability (HRV) provides indices of autonomic function and electrophysiology that are associated with cardiac risk. How habitual physical activity among older adults prospectively relates to HRV, including nonlinear indices of erratic sinus patterns, is not established. We hypothesized that increasing the levels of both total leisure-time activity and walking would be prospectively associated with more favorable time-domain, frequency-domain, and nonlinear HRV measures in older adults. METHODS AND RESULTS: We evaluated serial longitudinal measures of both physical activity and 24-hour Holter HRV over 5 years among 985 older US adults in the community-based Cardiovascular Health Study. After multivariable adjustment, greater total leisure-time activity, walking distance, and walking pace were each prospectively associated with specific, more favorable HRV indices, including higher 24-hour standard deviation of all normal-to-normal intervals (Ptrend=0.009, 0.02, 0.06, respectively) and ultralow-frequency power (Ptrend=0.02, 0.008, 0.16, respectively). Greater walking pace was also associated with a higher short-term fractal scaling exponent (Ptrend=0.003) and lower Poincaré ratio (Ptrend=0.02), markers of less erratic sinus patterns. CONCLUSIONS: Greater total leisure-time activity, and walking alone, as well, were prospectively associated with more favorable and specific indices of autonomic function in older adults, including several suggestive of more normal circadian fluctuations and less erratic sinoatrial firing. Our results suggest potential mechanisms that might contribute to lower cardiovascular mortality with habitual physical activity later in life.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1161/circulationaha.113.005361

Cites

54 of 54 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Heart Rate Variability: Standards of Measurement, Physiological Interpretation, and Clinical Use
Electrophysiology, T. F. O. T. E. S. O. C. T. N. A. (1996) · Circulation · doi:10.1161/01.cir.93.5.1043 · Cited by 17,159
Heart rate variability: Standards of measurement, physiological interpretation, and clinical use
Malik, M., Bigger, J. T., Camm, A. J., Kleiger, R. E., Malliani, A., Moss, A. J., & Schwartz, P. J. (1996) · European Heart Journal · doi:10.1093/oxfordjournals.eurheartj.a014868 · Cited by 15,289
Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology.
(1996) · PubMed · Cited by 5,666
Exercise and Physical Activity for Older Adults
Chodzko-Zajko, W. J., Proctor, D. N., Fiatarone Singh, M. A., Minson, C. T., Nigg, C. R., Salem, G. J., & Skinner, J. S. (2009) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181a0c95c · Cited by 5,153
American College of Sports Medicine position stand
Otis, C. L. (1997) · Medical Entomology and Zoology · Cited by 4,407
The Cardiovascular Health Study: design and rationale.
Fried, L. P., Borhani, N. O., Enright, P., Furberg, C. D., Gardin, J. M., Kronmal, R. A., Kuller, L. H., Manolio, T. A., Mittelmark, M. B., Newman, A., et al. (1991) · Annals of Epidemiology · doi:10.1016/1047-2797(91)90005-w · Cited by 3,652
Flexible regression models with cubic splines
Durrleman, S., & Simon, R. M. (1989) · Statistics in Medicine · doi:10.1002/sim.4780080504 · Cited by 2,722
A questionnaire for the assessment of leisure time physical activities
Taylor, H. L., Jacobs, D. R., Schucker, B., Knudsen, J., Leon, A. S., & Debacker, G. (1978) · Journal of Chronic Diseases · doi:10.1016/0021-9681(78)90058-9 · Cited by 1,848
Impact of Reduced Heart Rate Variability on Risk for Cardiac Events: The Framingham Heart Study
Tsuji, H., Larson, M. G., Venditti, F. J., Manders, E. S., Evans, J. C., Feldman, C. L., & Levy, D. (1996) · Circulation · doi:10.1161/01.cir.94.11.2850 · Cited by 1,762
Heart rate variability: measurement and clinical utility.
Kleiger, R. E., Stein, P. K., & Bigger, J. T. (2005) · Annals of Noninvasive Electrocardiology · doi:10.1111/j.1542-474x.2005.10101.x · Cited by 1,290
Self-citation

Flagged first, then by citations

Show all 54 references

Research works printed but not linked: 2

10.1249/MSS.0b013e3181994a91 · DOI
10.1016/1047-2797(91)90005-W · DOI · Paper page

Sorted by citations

Heart Rate Variability and Cardiac Vagal Tone in Psychophysiological Research – Recommendations for Experiment Planning, Data Analysis, and Data Reporting
Laborde, S., Mosley, E., & Thayer, J. F. (2017) · Frontiers in Psychology · doi:10.3389/fpsyg.2017.00213 · Cited by 2,336
“In previous 24 h monitoring bulky Holter devices were previously used which may cause some discomfort for participants (e.g., Soares-Miranda et al., 2014).”
Method
Impact of CARDIOrespiratory FITness on Arrhythmia Recurrence in Obese Individuals With Atrial Fibrillation
Pathak, R. K., Elliott, A., Middeldorp, M. E., Meredith, M., Mehta, A. B., Mahajan, R., Hendriks, J. M. L., Twomey, D., Kalman, J. M., Abhayaratna, W. P., et al. (2015) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2015.06.488 · Cited by 544
Autonomic nervous system dysfunction in psychiatric disorders and the impact of psychotropic medications: a systematic review and meta-analysis
Alvares, G. A., Quintana, D. S., Hickie, I. B., & Guastella, A. J. (2016) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.140217 · Cited by 503
Considerations in the assessment of heart rate variability in biobehavioral research
Quintana, D. S., & Heathers, J. A. J. (2014) · Frontiers in Psychology · doi:10.3389/fpsyg.2014.00805 · Cited by 395
Heart rate variability in the prediction of mortality: a systematic review and meta-analysis of healthy and patient populations
Jarczok, M. N., Weimer, K., Braun, C., Williams, D. P., Thayer, J. F., Gündel, H. O., & Balint, E. M. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104907 · Cited by 246
Association between physical activity and risk of incident arrhythmias in 402 406 individuals: evidence from the UK Biobank cohort
Elliott, A. D., Linz, D., Mishima, R. S., Kadhim, K., Gallagher, C., Middeldorp, M. E., Verdicchio, C. V., Hendriks, J., Lau, D. H., Gerche, A. L., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehz897 · Cited by 190
Effect of wearables on sleep in healthy individuals: a randomized crossover trial and validation study
Berryhill, S. M., Morton, C. J., Dean, A., Berryhill, A., Provencio‐Dean, N., Patel, S. I., Estep, L. E., Combs, D., Mashaqi, S., Gerald, L. B., et al. (2020) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.8356 · Cited by 162
Physical Exercise in the Oldest Old
Valenzuela, P. L., Castillo‐García, A., Morales, J. S., Izquierdo, M., Serra‐Rexach, J. A., Santos‐Lozano, A., & Lucia, A. (2019) · Comprehensive Physiology · doi:10.1002/cphy.c190002 · Cited by 152
Benefits from one session of deep and slow breathing on vagal tone and anxiety in young and older adults
Magnon, V., Dutheil, F., & Vallet, G. T. (2021) · Scientific Reports · doi:10.1038/s41598-021-98736-9 · Cited by 149
Are Changes in Heart Rate Variability in Middle‐Aged and Older People Normative or Caused by Pathological Conditions? Findings From a Large Population‐Based Longitudinal Cohort Study
Jandackova, V. K., Scholes, S., Britton, A. R., & Steptoe, A. (2016) · Journal of the American Heart Association · doi:10.1161/jaha.115.002365 · Cited by 139
Heart rate variability and depressive symptoms: a cross-lagged analysis over a 10-year period in the Whitehall II study
Jandackova, V. K., Britton, A. R., Malík, M., & Steptoe, A. (2016) · Psychological Medicine · doi:10.1017/s003329171600060x · Cited by 138
Heart rate variability and lifetime risk of cardiovascular disease: the Atherosclerosis Risk in Communities Study
Kubota, Y., Chen, L. Y., Whitsel, E. A., & Folsom, A. R. (2017) · Annals of Epidemiology · doi:10.1016/j.annepidem.2017.08.024 · Cited by 123
Heart–brain interactions in cardiac and brain diseases: why sex matters
Rossi, A., Mikaïl, N., Bengs, S., Haider, A., Treyer, V., Buechel, R. R., Wegener, S., Rauen, K., Tawakol, A. A., Merz, C. N. B., et al. (2022) · European Heart Journal · doi:10.1093/eurheartj/ehac061 · Cited by 124
Heart rate variability mediates the link between rumination and depressive symptoms: A longitudinal study
Carnevali, L., Thayer, J. F., BROSSCHOT, J. F., & Ottaviani, C. (2017) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2017.11.002 · Cited by 126
Heart Rate Variability for Classification of Alert Versus Sleep Deprived Drivers in Real Road Driving Conditions
Persson, A., Jonasson, H., Fredriksson, I., Wiklund, U., & Ahlstrom, C. H. G. (2020) · IEEE Transactions on Intelligent Transportation Systems · doi:10.1109/tits.2020.2981941 · Cited by 122
From psychological moments to mortality: a multidisciplinary synthesis on heart rate variability spanning the continuum of time
Kemp, A. H., Koenig, J., & Thayer, J. F. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.09.006 · Cited by 114
Effects of different exercise interventions on heart rate variability and cardiovascular health factors in older adults: a systematic review
Grässler, B., Thielmann, B., Böckelmann, I., & Hökelmann, A. (2021) · European Review of Aging and Physical Activity · doi:10.1186/s11556-021-00278-6 · Cited by 111
A literature review of heart rate variability in depressive and bipolar disorders
Bassett, D. L. (2015) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867415622689 · Cited by 113
Effects of office workstation type on physical activity and stress
Lindberg, C. M., Srinivasan, K. K., Gilligan, B., Razjouyan, J., Lee, H., Najafi, B., Canada, K., Mehl, M. R., Currim, F., Ram, S., et al. (2018) · Occupational and Environmental Medicine · doi:10.1136/oemed-2018-105077 · Cited by 102
Major depressive disorder with melancholia displays robust alterations in resting state heart rate and its variability: implications for future morbidity and mortality
Kemp, A. H., Quintana, D. S., Quinn, C. R., Hopkinson, P., & Harris, A. W. F. (2014) · Frontiers in Psychology · doi:10.3389/fpsyg.2014.01387 · Cited by 95
Heart Rate Variability and Cardiovascular Fitness: What We Know so Far
de Souza, H. C. D., Philbois, S. V., Veiga, A. C., & Aguilar, B. A. (2021) · Vascular Health and Risk Management · doi:10.2147/vhrm.s279322 · Cited by 97
Resting heart rate, heart rate variability and functional decline in old age
Ogliari, G., Mahinrad, S., Stott, D. J., Jukema, J. W., Mooijaart, S. P., Macfarlane, P. W., Clark, E., Kearney, P. M., Westendorp, R. G. J., de Craen, A. J. M., et al. (2015) · Canadian Medical Association Journal · doi:10.1503/cmaj.150462 · Cited by 87
On the health paradox of occupational and leisure-time physical activity using objective measurements: Effects on autonomic imbalance
Hallman, D., Jørgensen, M. B., & Holtermann, A. (2017) · PLoS ONE · doi:10.1371/journal.pone.0177042 · Cited by 85
Healthy lifestyle and heart rate variability in young adults
Aeschbacher, S., Bossard, M., Ruperti Repilado, F. J., Good, N., Schoen, T., Zimny, M., Probst-Hensch, N. M., Schmidt-Trucksäss, A., Risch, M., Risch, L., et al. (2016) · European Journal of Preventive Cardiology · doi:10.1177/2047487315623708 · Cited by 71
Differences Between High vs. Low Performance Chess Players in Heart Rate Variability During Chess Problems
García, J. P. F., Villafaina, S., Collado‐Mateo, D., Marcos, R. D. L. V., Olivares, P. R., & Clemente‐Suárez, V. J. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.00409 · Cited by 68
Effects of Tai Chi Exercise on Cancer-Related Fatigue in Patients With Nasopharyngeal Carcinoma Undergoing Chemoradiotherapy: A Randomized Controlled Trial
Zhou, W., Wan, Y., Chen, Q., Qiu, Y., & Luo, X. (2017) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2017.10.021 · Cited by 67
Exercise Frequency Determines Heart Rate Variability Gains in Older People: A Meta-Analysis and Meta-Regression
Raffin, J., Barthélemy, J., Duprè, C., Pichot, V., Berger, M., Féasson, L., Busso, T., Costa, A. D., Colvez, A., Montuy-Coquard, C., et al. (2019) · Sports Medicine · doi:10.1007/s40279-019-01097-7 · Cited by 66
Working postures and physical activity among registered nurses
Schall, M. C., Fethke, N. B., & Chen, H. (2016) · Applied Ergonomics · doi:10.1016/j.apergo.2016.01.008 · Cited by 72
Valsalva maneuver unveils central baroreflex dysfunction with altered blood pressure control in persons with a history of mild traumatic brain injury
Hilz, M., Liu, M., Koehn, J., Wang, R.-H., Ammon, F., Flanagan, S. R., & Hösl, K. (2016) · BMC Neurology · doi:10.1186/s12883-016-0584-5 · Cited by 60
Physical activity, body mass index and heart rate variability-based stress and recovery in 16 275 Finnish employees: a cross-sectional study
Föhr, T., Pietilä, J., Helander, E. E., Myllymäki, T., Lindholm, H. J., Rusko, H. K., & Kujala, U. M. (2016) · BMC Public Health · doi:10.1186/s12889-016-3391-4 · Cited by 74
Physical Exercise and Immune System in the Elderly: Implications and Importance in COVID-19 Pandemic Period
Scartoni, F. R., Sant’Ana, L. D. O., Murillo‐Rodríguez, E., Yamamoto, T., Imperatori, C., Budde, H., Vianna, J. M., & Machado, S. E. D. C. (2020) · Frontiers in Psychology · doi:10.3389/fpsyg.2020.593903 · Cited by 60
Exercise, Physical Activity, and Cardiometabolic Health: Insights into the Prevention and Treatment of Cardiometabolic Diseases
Rao, P., Belanger, M. J., & Robbins, J. (2021) · Cardiology in Review · doi:10.1097/crd.0000000000000416 · Cited by 66
Prolonged Sitting is Associated with Attenuated Heart Rate Variability during Sleep in Blue-Collar Workers
Hallman, D., Sato, T. D. O., Kristiansen, J., Gupta, N., Skotte, J. H., & Holtermann, A. (2015) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph121114811 · Cited by 54
Physical Exercise for Late-Life Depression: Effects on Heart Rate Variability
Toni, G., Murri, M. B., Piepoli, M. F., Zanetidou, S., Cabassi, A., Squatrito, S., Bagnoli, L., Piras, A., Mussi, C., Senaldi, R., et al. (2016) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2016.08.005 · Cited by 49
Frail older adults are more likely to have autonomic dysfunction: A systematic review and meta-analysis
Debain, A., Loosveldt, F., Knoop, V., Costenoble, A., Lieten, S., Petrović, M., & Bautmans, I. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.101925 · Cited by 48
Functional and structural adaptations of the coronary macro- and microvasculature to regular aerobic exercise by activation of physiological, cellular, and molecular mechanisms: ESC Working Group on Coronary Pathophysiology and Microcirculation position paper
Koller, Á., Laughlin, M. H., Cenko, E., de Wit, C., Tóth, K., Bugiardini, R., Trifunović, D., Vavlukis, M., Manfrini, O., Lelbach, A., et al. (2021) · Cardiovascular Research · doi:10.1093/cvr/cvab246 · Cited by 46
Heart Rate Variability Mainly Relates to Cognitive Executive Functions and Improves Through Exergame Training in Older Adults: A Secondary Analysis of a 6-Month Randomized Controlled Trial
Eggenberger, P., Annaheim, S., Kündig, K. A., Rossi, R. M., Münzer, T., & de Bruin, E. D. (2020) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2020.00197 · Cited by 45
Heart rate variability in patients with systemic lupus erythematosus: a systematic review and methodological considerations
Matusik, P. S., Matusik, P. T., & Stein, P. K. (2018) · Lupus · doi:10.1177/0961203318771502 · Cited by 46
Self-citation
healthy lifestyle and cardiac vagal modulation over 10 years: whitehall II cohort study
Jandackova, V. K., Scholes, S., Britton, A., & Steptoe, A. (2019) · Journal of the American Heart Association · doi:10.1161/jaha.119.012420 · Cited by 39
Potential biological pathways linking Type-D personality and poor health: A cross-sectional investigation
Jandackova, V. K., Koenig, J., Jarczok, M. N., Fischer, J. E., & Thayer, J. F. (2017) · PLoS ONE · doi:10.1371/journal.pone.0176014 · Cited by 40
Psychophysiological stress response of adolescent chess players during problem-solving tasks
García, J. P. F., Pereira, T. S., Castro, M. A., Santos, A. C., & Villafaina, S. (2019) · Physiology & Behavior · doi:10.1016/j.physbeh.2019.112609 · Cited by 38
Complexity-Based Decoding of the Coupling Among Heart Rate Variability (HRV) and Walking Path
Kamal, S. M., Babini, M. H., Krejcar, O., & Namazi, H. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.602027 · Cited by 37
Physical activity is associated with cardiac autonomic function in adolescent men
Tornberg, J., Ikäheimo, T. M., Kiviniemi, A. M., Pyky, R., Hautala, A. J., Mäntysaari, M., Jämsä, T. J., & Korpelainen, R. (2019) · PLoS ONE · doi:10.1371/journal.pone.0222121 · Cited by 37
Relationship between domains of physical activity and cardiac autonomic modulation in adults: a cross-sectional study
Tebar, W. R., Ritti‐Dias, R. M., Mota, J. A. P. S., Farah, B. Q., Saraiva, B. T. C., Damato, T. M. D. M., Delfino, L. D., Aguilar, B. A. S., dos Santos, A. B., Silva, S. C. B., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-72663-7 · Cited by 37
Heart rate variability as a function of menopausal status, menstrual cycle phase, and estradiol level
Ramesh, S., James, M. T., Holroyd-Leduc, J. M., Wilton, S. B., Sola, D. Y., & Ahmed, S. B. (2022) · Physiological Reports · doi:10.14814/phy2.15298 · Cited by 42
Parsing inter- and intra-individual variability in key nervous system mechanisms of stress responsivity and across functional domains
Rab, S. L., & Admon, R. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.09.007 · Cited by 36
Exercise, Heart Rate Variability, and Longevity
Poirier, P. (2014) · Circulation · doi:10.1161/circulationaha.114.009778 · Cited by 37
Heart rate variability
Anderson, T. A. (2017) · Current Opinion in Anaesthesiology · doi:10.1097/aco.0000000000000530 · Cited by 34
Heart rate variability and the risk of heart failure and its subtypes in post-menopausal women: The Women’s Health Initiative study
Baig, M., Moafi-Madani, M., Qureshi, R., Roberts, M. B., Allison, M., Manson, J. E., LaMonte, M. J., Liu, S., & Eaton, C. B. (2022) · PLoS ONE · doi:10.1371/journal.pone.0276585 · Cited by 33
Relationship between linear and nonlinear dynamics of heart rate and impairment of lung function in COPD patients
Mazzuco, A., Medeiros, W. M., Sperling, M. P. R., de Souza, A. S., Alencar, M. C. N., Arbex, F. F., Neder, J. A., Arena, R. A., & Borghi‐Silva, A. (2015) · International Journal of COPD · doi:10.2147/copd.s81736 · Cited by 34
Relationship between heart rate variability and body mass index: A cross-sectional study of preschool children
Speer, K. E., Koenig, J., Telford, R. M., OLIVE, L. S., Mara, J. K., Semple, S., Naumovski, N., Telford, R. D., & McKune, A. J. (2021) · Preventive Medicine Reports · doi:10.1016/j.pmedr.2021.101638 · Cited by 32
Exercise, Arterial Crosstalk-Modulation, and Inflammation in an Aging Population: The ExAMIN AGE Study
Streese, L., Deiseroth, A., Schäfer, J., Schmidt‐Trucksäss, A., & Hanssen, H. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00116 · Cited by 31
Lifelong Physical Activity and Cardiovascular Autonomic Function in Midlife
Kiviniemi, A. M., PERKIÖMÄU, N., AUVINEN, J. P., Herrala, S., Hautala, A. J., Ahola, R., Tammelin, T., Tulppo, M. P., Järvelin, M., Korpelainen, R., et al. (2016) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000942 · Cited by 28
Particulate matter air pollution and reduced heart rate variability: How the associations vary by particle size in Shanghai, China
Huang, C., Tang, M., Li, H., Wen, J., Wang, C., Gao, Y., Hu, J., Lin, J., & Chen, R. (2020) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2020.111726 · Cited by 28
Yoga and breathing technique training in patients with heart failure and preserved ejection fraction: study protocol for a randomized clinical trial
Lopes, C. P., Danzmann, L. C., Moraes, R. S., Vieira, P. J. C., Meurer, F. F., Soares, D. D. S., Chiappa, G. R., Guimarães, L. S. P., Leitão, S. A. T., Ribeiro, J. P., et al. (2018) · Trials · doi:10.1186/s13063-018-2802-5 · Cited by 28
Effects of Exercise Training on Heart Rate Variability in Healthy Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Amekran, Y., & Hangouche, A. J. E. (2024) · Cureus · doi:10.7759/cureus.62465 · Cited by 32
Does Virtual Reality-based Kinect Dance Training Paradigm Improve Autonomic Nervous System Modulation in Individuals with Chronic Stroke?
Sampaio, L. M. M., Subramaniam, S., Arena, R. A., & Bhatt, T. S. (2016) · PubMed Central · Cited by 27
Advancing Sports Cardiology: Integrating Artificial Intelligence with Wearable Devices for Cardiovascular Health Management
Zheng, X. H., Liu, Z., Liu, J., Hu, C., Du, Y., Li, J., Pan, Z., & Ding, K. (2025) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c22895 · Cited by 30
Effects of Cardiovascular Interval Training in Healthy Elderly Subjects: A Systematic Review
Sant’Ana, L. D. O., Machado, S. E. D. C., Ribeiro, A. A. D. S., dos Reis, N. R., Campos, Y., Vieira, J. G., Scartoni, F. R., Brown, A., Monteiro, E. R., Novaes, J. D. S., et al. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00739 · Cited by 24
The Effects of Passive Simulated Jogging on Short-Term Heart Rate Variability in a Heterogeneous Group of Human Subjects
Adams, J. A., Patel, S. G., Lopez, J. R., & Sackner, M. A. (2018) · Journal of Sports Medicine · doi:10.1155/2018/4340925 · Cited by 24
Associations of Sleep Quality and Awake Physical Activity with Fluctuations in Nocturnal Blood Pressure in Patients with Cardiovascular Risk Factors
Kadoya, M., Koyama, H., Kurajoh, M., Naka, M., Miyoshi, A., Kanzaki, A., Kakutani, M., Shoji, T., Moriwaki, Y., Yamamoto, T., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0155116 · Cited by 23
Association between Objective Activity Intensity and Heart Rate Variability: Cardiovascular Disease Risk Factor Mediation (CARDIA)
Pope, Z., Gabriel, K. P., Whitaker, K. M., Chen, L. Y., Schreiner, P. J., Jacobs, D. R., Sternfeld, B., Carr, J. J., Lloyd‐Jones, D. M., & Pereira, M. A. (2020) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000002259 · Cited by 23
A Neurovisceral Integrative Study on Cognition, Heart Rate Variability, and Fitness in the Elderly
Matos, F. D. O., Vido, A., Garcia, W. F., Lopes, W. A., & Pereira, A. (2020) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2020.00051 · Cited by 23
The interplay of self-critical rumination and resting heart rate variability on subjective well-being and somatic symptom distress: A prospective study
Kocsel, N., Köteles, F. G., Galambos, A., & Kökönyei, G. (2021) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2021.110676 · Cited by 27
Targeting autonomic nervous system as a biomarker of well-ageing in the prevention of stroke
Barthélemy, J., Pichot, V., Hupin, D., Berger, M., Celle, S., Mouhli, L., Bäck, M., Lacour, J.-R., & Roche, F. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.969352 · Cited by 24
Ambulatory heart rate range predicts mode-specific mortality and hospitalisation in chronic heart failure
Cubbon, R. M., Ruff, N. L., Groves, D., Eleuteri, A., Denby, C. E., Kearney, L. C., Ali, N., Walker, A. M., Jamil, H. A., Gierula, J., et al. (2015) · Heart · doi:10.1136/heartjnl-2015-308428 · Cited by 22
Effect of an aerobic exercise intervention on cardiac autonomic regulation: A worksite RCT among cleaners
Hallman, D., Holtermann, A., Søgaard, K., Krustrup, P., Kristiansen, J., & Korshøj, M. (2016) · Physiology & Behavior · doi:10.1016/j.physbeh.2016.11.031 · Cited by 21
A Simple Home-Based Lifestyle Intervention Program to Improve Cardiac Autonomic Regulation in Patients with Increased Cardiometabolic Risk
Lucini, D., Malacarne, M., Gatzemeier, W., & Pagani, M. (2020) · Sustainability · doi:10.3390/su12187671 · Cited by 22
Effects of Different Exercise Interventions on Cardiac Autonomic Control and Secondary Health Factors in Middle-Aged Adults: A Systematic Review
Grässler, B., Thielmann, B., Böckelmann, I., & Hökelmann, A. (2021) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd8080094 · Cited by 20
Association of physical activity and heart rate variability in people with overweight and obesity: A systematic review
Sinha, M. K., Vaishali, K., Maiya, A. G., Shivashankar, K. N., Shashikiran, U., & Ravi Shankar, N. (2023) · F1000Research · doi:10.12688/f1000research.124707.1 · Cited by 20
Predicting physical functioning status in older adults: insights from wrist accelerometer sensors and derived digital biomarkers of physical activity
Fan, L., Zhao, J., Hu, Y., Zhang, J., Wang, X., Wang, F., Wu, M., & Lin, T. (2024) · Journal of the American Medical Informatics Association · doi:10.1093/jamia/ocae224 · Cited by 20
Vitamin D, the autonomic nervous system, and cardiovascular risk
Mann, M. C., Hollenberg, M. D., Hanley, D. A., & Ahmed, S. B. (2015) · Physiological Reports · doi:10.14814/phy2.12349 · Cited by 20
Heart rate variability predicts outcome of short‐term psychotherapy at the workplace
Balint, E. M., Daniele, V., Langgartner, D., Reber, S. O., Rothermund, E., Gündel, H., von Wietersheim, J., Buckley, T. A., & Jarczok, M. N. (2022) · Psychophysiology · doi:10.1111/psyp.14150 · Cited by 22
Effects of 3‐month Qigong exercise on heart rate variability and respiration in anxious college students
Sun, J., Zhuo, J., Chu, H., Wang, J., Chen, T., Li, B., Lu, T., Zheng, H., Xu, Y., Dong, J., et al. (2023) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/sms.14521 · Cited by 19
Autonomic cardiac regulation, blood pressure and cardiorespiratory fitness responses to different training doses over a 12 week group program in the elderly
McKune, A. J., Peters, B., Ramklass, S., van Heerden, J., Roberts, C., Krejčí, J., & Botek, M. (2017) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2017.01.012 · Cited by 22
Heart and Brain Responses to Real Versus Simulated Chess Games in Trained Chess Players: A Quantitative EEG and HRV Study
García, J. P. F., Pereira, T. S., Castro, M. A., Santos, A. C., & Villafaina, S. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16245021 · Cited by 19
Physiological and Behavioral Benefits for People and Horses during Guided Interactions at an Assisted Living Residence
Baldwin, A. L., Rector, B. K., & Alden, A. C. (2021) · Behavioral Sciences · doi:10.3390/bs11100129 · Cited by 18
Impact of Basketball Match on the Pre-Competitive Anxiety and HRV of Youth Female Players
García-Ceberino, J. M., García, J. P. F., & Villafaina, S. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19137894 · Cited by 18
Long-COVID-19 autonomic dysfunction: An integrated view in the framework of inflammaging
Giunta, S., Giordani, C., Luca, M. D., & Olivieri, F. (2024) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2024.111915 · Cited by 20
Exercise and Arterial Modulation in Children: The EXAMIN YOUTH Study
Endes, K., Köchli, S., Zahner, L., & Hanssen, H. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00043 · Cited by 18
Effects of Proximity between Companion Dogs and Their Caregivers on Heart Rate Variability Measures in Older Adults: A Pilot Study
Ortmeyer, H. K., & Katzel, L. I. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17082674 · Cited by 18
Heart Rate Variability Is Associated with Exercise Capacity in Patients with Cardiac Syndrome X
Lu, D., Yang, A. C., Cheng, H., Lu, T., Yu, W., Chen, C., & Sung, S. (2016) · PLoS ONE · doi:10.1371/journal.pone.0144935 · Cited by 17
The Association Between IGF-I and IGFBP-3 and Incident Diabetes in an Older Population of Men and Women in the Cardiovascular Health Study
Aneke-Nash, C. S., Xue, X., Qi, Q., Biggs, M. L., Cappola, A. R., Kuller, L. H., Pollak, M., Psaty, B. M., Siscovick, D. S., Mukamal, K. J., et al. (2017) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2017-01273 · Cited by 17
Self-citation
Effects of stress management interventions on heart rate variability in adults with cardiovascular disease: a systematic review and meta-analysis
Gathright, E. C., Hughes, J. W., Sun, S., Storlazzi, L. E., DeCosta, J., Balletto, B. L., Carey, M. P., Scott‐Sheldon, L. A. J., & Salmoirago‐Blotcher, E. (2024) · Journal of Behavioral Medicine · doi:10.1007/s10865-024-00468-4 · Cited by 19
Adiposity and physical activity are related to heart rate variability: the African‐PREDICT study
Köchli, S., Schutte, A. E., & Kruger, R. (2020) · European Journal of Clinical Investigation · doi:10.1111/eci.13330 · Cited by 16
Heart rate fluctuation predicts mortality in critically ill patients in the intensive care unit: a retrospective cohort study
Guo, Q., Xiao, Z., Lin, M.-H., Yuan, G., Qiu, Q., Yang, Y., Zhao, H., Zhang, Y., Zhou, S., & Wang, J. (2021) · Annals of Translational Medicine · doi:10.21037/atm-20-7897 · Cited by 15
Consecutive ultra-short-term heart rate variability to track dynamic changes in autonomic nervous system during and after exercise
Chen, X., Yao, R., Yin, G., & Li, J. (2017) · Physiological Measurement · doi:10.1088/1361-6579/aa52b3 · Cited by 17
Influence of ageing on circadian rhythm of heart rate variability in healthy subjects
Accardo, A., Merlo, M., Silveri, G., Popolo, L. D., Libera, L. D., Restivo, L., Cinquetti, M., Cannata, A. N., & Sinagra, G. (2020) · Journal of Cardiovascular Medicine · doi:10.2459/jcm.0000000000001048 · Cited by 15
Evaluating Physical Stress across Task Difficulty Levels in Augmented Reality-Assisted Industrial Maintenance
Alessa, F. M., Alhaag, M. H., Al-Harkan, I. M., Nasr, M. M., Kaid, H., & Hammami, N. (2023) · Applied Sciences · doi:10.3390/app14010363 · Cited by 15
Association between Cardiac Autonomic Neuropathy and Coronary Artery Lesions in Patients with Type 2 Diabetes
Liu, L., Wu, Q., Yan, H., Chen, B., Zheng, X., & Zhou, Q. (2020) · Disease Markers · doi:10.1155/2020/6659166 · Cited by 15
Heart Rate Variability During Physical Exercise Is Associated With Improved Cognitive Performance in Alzheimer's Dementia Patients—A Longitudinal Feasibility Study
Schwarck, S., Busse, N., Ziegler, G., Glanz, W., Becke, A., & Düzel, E. (2021) · Frontiers in Sports and Active Living · doi:10.3389/fspor.2021.684089 · Cited by 14
Effects of Endurance Exercise Intensities on Autonomic and Metabolic Controls in Children with Obesity: A Feasibility Study Employing Online Exercise Training
Calcaterra, V., Bernardelli, G., Malacarne, M., Vandoni, M., Mannarino, S., Pellino, V. C., Larizza, C., Pagani, M., Zuccotti, G., & Lucini, D. (2023) · Nutrients · doi:10.3390/nu15041054 · Cited by 14
Clinical Impact of Early Rhythm Control and Healthy Lifestyles in Patients With Atrial Fibrillation
Lee, S., Choi, E., Lee, S. W., Han, K., Oh, S., & Lip, G. Y. H. (2024) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2024.02.016 · Cited by 14
Association Between Occupational, Sport, and Leisure Related Physical Activity and Baroreflex Sensitivity
Climie, R. E., Boutouyrie, P., Perier, M., Chaussade, E., Plichart, M., Offredo, L., Guibout, C., van Sloten, T. T., Thomas, F., Pannier, B., et al. (2019) · Hypertension · doi:10.1161/hypertensionaha.119.13461 · Cited by 14
Effects of a diabetes-specific care model for hip fractured older patients with diabetes: A randomized controlled trial
Tseng, M., Liang, J., Wang, J., Yang, C., Wu, C., Cheng, H., Chen, C.-Y., Lin, Y., Wang, W., & Shyu, Y. L. (2019) · Experimental Gerontology · doi:10.1016/j.exger.2019.110689 · Cited by 13
Neurophysiological and autonomic responses of high and low level chess players during difficult and easy chess endgames – A quantitative EEG and HRV study
Villafaina, S., Castro, M. A., Pereira, T. S., Santos, A. C., & García, J. P. F. (2021) · Physiology & Behavior · doi:10.1016/j.physbeh.2021.113454 · Cited by 14
Frailty and its associated factors among older adults with cancer undergoing chemotherapy as outpatients: A cross-sectional study
Jeon, M., Jang, H., Lim, A., & Kim, S. (2022) · European Journal of Oncology Nursing · doi:10.1016/j.ejon.2022.102192 · Cited by 13
Heart Rate Variability and Salivary Biomarkers Differences between Fibromyalgia and Healthy Participants after an Exercise Fatigue Protocol: An Experimental Study
Costa, A. R., Freire, A. C. A., Parraça, J. A., Silva, V., Tomás-Carús, P., & Villafaina, S. (2022) · Diagnostics · doi:10.3390/diagnostics12092220 · Cited by 13
Discovery of associative patterns between workplace sound level and physiological wellbeing using wearable devices and empirical Bayes modeling
Srinivasan, K. K., Currim, F., Lindberg, C. M., Razjouyan, J., Gilligan, B., Lee, H., Canada, K., Goebel, N., Mehl, M. R., Lunden, M. M., et al. (2023) · npj Digital Medicine · doi:10.1038/s41746-022-00727-1 · Cited by 14
Changes in Insulin‐Like Growth Factor‐I and Its Binding Proteins Are Associated with Diabetes Mellitus in Older Adults
Aneke-Nash, C. S., Parrinello, C. M., Rajpathak, S. N., Rohan, T. E., Strotmeyer, E. S., Kritchevsky, S. B., Psaty, B. M., Bůžková, P., Kizer, J. R., Newman, A. B., et al. (2015) · Journal of the American Geriatrics Society · doi:10.1111/jgs.13390 · Cited by 13

Authors: Soares-Miranda, L., Sattelmair, J., Chaves, P., Duncan, G. E., Siscovick, D. S., Stein, P. K., & Mozaffarian, D.
Affiliations: From the Department of Epidemiology, Harvard School of Public Health, Boston, MA (L.S.-M., J.S., D.M.); Research Centre in Physical Activity, Health and Leisure, Faculty of Sport, University of Porto, Portugal (L.S.-M.); Benjamin Leon Center for Geriatric Research and Education and Department of Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL (P.C.); Department of Epidemiology, University of Washington, Seattle, WA (G.E.D., D.S.S.); Department of Medicine,...
Brigham and Women's Hospital (US)
ORCID: Chaves, Paulo
Duncan, Glen E.
Siscovick, David S.
Stein, Phyllis K.
Mozaffarian, Dariush
Venue: Circulation
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2014-05-27
Volume: 129
Issue: 21
Pages: 2100-2110
ISSN: 0009-7322 (ISSN-L)
1524-4539
DOI: 10.1161/circulationaha.113.005361
PMC: PMC4038662
OpenAlex: W1997588201
Cited by: 228
References: 54
Citations by year: 2026: 8 · 2025: 20 · 2024: 21 · 2023: 20 · 2022: 25 · 2021: 23 · 2020: 31 · 2019: 18 · 2018: 6 · 2017: 20 · 2016: 15 · 2015: 15 · 2014: 5
FWCI: 12.60
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Circulation (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health (n01hc085082-026, n01hc085081-021, n01hc085079-024, n01hc085083-027, n01hc085080-026, n01hc085086-022, n01hc55222-0-0-0)
National Institute on Aging (R56AG023629, AG023629, R01AG023629)
National Heart, Lung, and Blood Institute (N01 HC085086, N0-1-HC-85239, N01 HC085079, N01 HC085083, N01 HC085080, N01 HC55222, HHSN268201200036C, N01HC085082, U01HL080295, N01 HC055222, N01 HC085081, HL080295, R01HL080295)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
Keywords: heart rate variability, physical activity, older adults, leisure-time activities, walking, walking speed, autonomic function, fractal scaling exponent, circadian rhythm, cardiovascular mortality, nonlinear HRV measures
MeSH terms: Aged, Cardiovascular Diseases, Cross-Sectional Studies, Female, Follow-Up Studies, Health Status, Heart Rate, Humans, Leisure Activities, Longitudinal Studies, Male, Motor Activity, Prospective Studies, Electrocardiography, Ambulatory, Walking

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Physical Activity and Heart Rate Variability in Older Adults: The Cardiovascular Health Study

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks