Cited by 676Atrial Fibrillation Management and OutcomesCardiac pacing and defibrillation studiesCardiovascular and Diving-Related Complications

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Temporal Relationship Between Subclinical Atrial Fibrillation and Embolic Events

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Brambatti, Michela, Connolly, Stuart J., Gold, Michael R., Morillo, Carlos A., Capucci, Alessandro, Muto, Carmine, Lau, Chu P., Van Gelder, Isabelle C., Hohnloser, Stefan H., Carlson, Mark, Fain, Eric, Nakamya, Juliet, Mairesse, Georges H., Halytska, Marta, Deng, Wei Q., Israel, Carsten W, Healey, Jeff S.·2014·Circulation

DOI 10.1161/circulationaha.113.007825

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Abstract

BACKGROUND: Among patients with implantable pacemakers and defibrillators, subclinical atrial fibrillation (SCAF) is associated with an increased risk of stroke; however, there is limited understanding of their temporal relationship. METHODS AND RESULTS: The Asymptomatic Atrial Fibrillation and Stroke Evaluation in Pacemaker Patients and the Atrial Fibrillation Reduction Atrial Pacing Trial (ASSERT) enrolled 2580 pacemaker and defibrillator patients aged ≥65 years with a history of hypertension but without a history of atrial fibrillation. Pacemakers and implantable cardioverter-defibrillators precisely logged the time and duration of all episodes of SCAF and recorded electrograms that were adjudicated by experts. We examined the temporal relationship between SCAF >6 minutes in duration and stroke or systemic embolism. Of 51 patients who experienced stroke or systemic embolism during follow-up, 26 (51%) had SCAF. In 18 patients (35%), SCAF was detected before stroke or systemic embolism. However, only 4 patients (8%) had SCAF detected within 30 days before stroke or systemic embolism, and only 1 of these 4 patients was experiencing SCAF at the time of the stroke. In the 14 patients with SCAF detected >30 days before stroke or systemic embolism, the most recent episode occurred at a median interval of 339 days (25th to 75th percentile, 211-619) earlier. Eight patients (16%) had SCAF detected only after their stroke, despite continuous monitoring for a median duration of 228 days (25th to 75th percentile, 202-719) before their event. CONCLUSIONS: Although SCAF is associated with an increased risk of stroke and embolism, very few patients had SCAF in the month before their event. CLINICAL TRIAL REGISTRATION URL: http://www.clinicaltrials.gov. Unique identifier: NCT00256152.

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Atrial fibrillation as an independent risk factor for stroke: the Framingham study
Wolf, P. A., Abbott, R. D., & Kannel, W. B. (1991) · Stroke · doi:10.1161/01.str.22.8.983 · Cited by 7,388
Refining Clinical Risk Stratification for Predicting Stroke and Thromboembolism in Atrial Fibrillation Using a Novel Risk Factor-Based Approach
Lip, G. Y. H., Nieuwlaat, R., Pisters, R., Lane, D. A., & Crijns, H. J. G. M. (2010) · Chest · doi:10.1378/chest.09-1584 · Cited by 6,879
Untitled work
Kearon (2012) · doi:10.1378/chest.11-2301 · Cited by 6,119
Subclinical atrial fibrillation and the risk of stroke
Healey, J. S., Connolly, S. J., Gold, M. R., Israel, C. W., Van Gelder, I. C., Capucci, A., Lau, C. P., Fain, E., Yang, S., Bailleul, C., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1105575 · Cited by 2,100
Prevalence, incidence, prognosis, and predisposing conditions for atrial fibrillation: population-based estimates 11Reprints are not available.
Kannel, W. B., Wolf, P. A., Benjamin, E. J., & Levy, D. (1998) · The American Journal of Cardiology · doi:10.1016/s0002-9149(98)00583-9 · Cited by 2,033
Mechanisms of thrombogenesis in atrial fibrillation: Virchow's triad revisited
Watson, T., Shantsila, E., & Lip, G. Y. H. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60040-4 · Cited by 1,124
Antithrombotic Therapy for Atrial Fibrillation
You, J. J., Singer, D. E., Howard, P. A., Lane, D. A., Eckman, M. H., Fang, M. C., Hylek, E. M., Schulman, S., Go, A. S., Hughes, M., et al. (2012) · CHEST Journal · doi:10.1378/chest.11-2304 · Cited by 933
The Relationship Between Daily Atrial Tachyarrhythmia Burden From Implantable Device Diagnostics and Stroke Risk: The TRENDS Study
Glotzer, T. V., Daoud, E. G., Wyse, D. G., Singer, D. E., Ezekowitz, M. D., Hilker, C., Miller, C., Qi, D., & Ziegler, P. D. (2009) · Circulation: Arrhythmia and Electrophysiology · doi:10.1161/circep.109.849638 · Cited by 879 · cited 1×
“190 Systemic embolism 4 (16) 1 (4) 5 (10) 0.”
Inflammation in Atrial Fibrillation
Guo, Y., Lip, G. Y. H., & Apostolakis, S. Z. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.04.063 · Cited by 868
Atrial High Rate Episodes Detected by Pacemaker Diagnostics Predict Death and Stroke: Report of the Atrial Diagnostics Ancillary Study of the MOde Selection Trial (MOST)
Glotzer, T. V., Hellkamp, A. S., Zimmerman, J., Sweeney, M. O., Yee, R., Marinchak, R., Cook, J., Paraschos, A., Love, J., Radoslovich, G., et al. (2003) · Circulation · doi:10.1161/01.cir.0000057981.70380.45 · Cited by 750

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Anderson K, Benzauquen BS. Do patients with pacemaker-detected atrial fibrillation receive appropriate anticoagulation? Europace. 2011;13:519.

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2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)
Hindricks, G., Potpara, T., Dagres, N., Arbelo, E., Bax, J. J., Blomström‐Lundqvist, C., Boriani, G., Castella, M., Dan, G.-A., Dilaveris, P., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehaa612 · Cited by 10,550
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P. F., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castellà, M., Diener, H., Heidbüchel, H., Hendriks, J., et al. (2016) · EP Europace · doi:10.1093/europace/euw295 · Cited by 6,438
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw210 · Cited by 6,418
2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines
Joglar, J. A., Chung, M. K., Armbruster, A. L., Benjamin, E. J., Chyou, J. Y., Cronin, E. M., Deswal, A. M., Eckhardt, L. L., Goldberger, Z. D., Gopinathannair, R., et al. (2023) · Circulation · doi:10.1161/cir.0000000000001193 · Cited by 3,072
Stroke risk factors, genetics, and prevention
Boehme, A. K., Esenwa, C., & Elkind, M. S. V. (2017) · Circulation Research · doi:10.1161/circresaha.116.308398 · Cited by 1,952
Epidemiology of Atrial Fibrillation in the 21st Century
Kornej, J., Börschel, C. S., Benjamin, E. J., & Schnabel, R. B. (2020) · Circulation Research · doi:10.1161/circresaha.120.316340 · Cited by 1,625
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., et al. (2016) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezw313 · Cited by 1,403
Pathophysiology and treatment of stroke: present status and future perspectives
Kuriakose, D., & Xiao, Z. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21207609 · Cited by 1,350
“In other instances, individuals harboring genetic mutations specific to AF can be affected by stroke long before the onset of AF [52,53].”
Background
Atrial fibrillation in patients with cryptogenic stroke
Gladstone, D. J., Spring, M., Dorian, P., Panzov, V., Thorpe, K. E., Hall, J., Vaid, H., O'Donnell, M., Laupacis, A., Côté, R., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1311376 · Cited by 1,276
Antithrombotic Therapy for Atrial Fibrillation
Lip, G. Y. H., Banerjee, A., Boriani, G., Chiang, C. E., Fargo, R. A., Freedman, B., Lane, D. A., Ruff, C. T., Turakhia, M. P., Werring, D. J., et al. (2018) · CHEST Journal · doi:10.1016/j.chest.2018.07.040 · Cited by 963
2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation
Joglar, J. A., Chung, M. K., Armbruster, A. L., Benjamin, E. J., Chyou, J. Y., Cronin, E. M., Deswal, A., Eckhardt, L. L., Goldberger, Z. D., Gopinathannair, R., et al. (2024) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2023.08.017 · Cited by 933
2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation
Tzeis, S. E., Gerstenfeld, E. P., Kalman, J. M., Saad, E., Shamloo, A. S., Andrade, J. G., Barbhaiya, C. R., Baykaner, T., Bovéda, S., Calkins, H. G., et al. (2024) · EP Europace · doi:10.1093/europace/euae043 · Cited by 724
Atrial Fibrillation and Mechanisms of Stroke: Time for a New Model
Kamel, H., Okin, P. M., Elkind, M. S. V., & Iadecola, C. (2016) · Stroke · doi:10.1161/strokeaha.115.012004 · Cited by 627
Mass Screening for Untreated Atrial Fibrillation: The STROKESTOP Study
Svennberg, E., Engdahl, J., Al-Khalili, F., Friberg, L., Frykman, V., & Rosenqvist, M. (2015) · Circulation · doi:10.1161/circulationaha.114.014343 · Cited by 605
Duration of device-detected subclinical atrial fibrillation and occurrence of stroke in ASSERT
Gelder, I. C. V., Healey, J. S., Crijns, H. J. G. M., Wang, J., Hohnloser, S. H., Gold, M. R., Capucci, A., Lau, C., Morillo, C. A., Hobbelt, A. H., et al. (2017) · European Heart Journal · doi:10.1093/eurheartj/ehx042 · Cited by 604
Implantable loop recorder detection of atrial fibrillation to prevent stroke (The LOOP Study): a randomised controlled trial
Svendsen, J. H., Diederichsen, S. Z., Højberg, S., Krieger, D. W., Graff, C., Kronborg, C., Olesen, M. S., Nielsen, J. B., Holst, A. G., Brandes, A., et al. (2021) · The Lancet · doi:10.1016/s0140-6736(21)01698-6 · Cited by 550
Screening for Atrial Fibrillation
Freedman, B., Camm, A. J., Calkins, H. G., Healey, J. S., Rosenqvist, M., Wang, J., Albert, C. M., Anderson, C. S., Antoniou, S., Benjamin, E. J., et al. (2017) · Circulation · doi:10.1161/circulationaha.116.026693 · Cited by 559
HRS Expert Consensus Statement on remote interrogation and monitoring for cardiovascular implantable electronic devices
Slotwiner, D. J., Varma, N., Akar, J. G., Annas, G. J., Beardsall, M., Fogel, R. I., Galizio, N. O., Glotzer, T. V., Leahy, R. A., Love, C. J., et al. (2015) · Heart Rhythm · doi:10.1016/j.hrthm.2015.05.008 · Cited by 533
Stroke prevention in atrial fibrillation
Freedman, B., Potpara, T., & Lip, G. Y. H. (2016) · The Lancet · doi:10.1016/s0140-6736(16)31257-0 · Cited by 484
2014 Focused Update of the Canadian Cardiovascular Society Guidelines for the Management of Atrial Fibrillation
Verma, A., Cairns, J. A., Mitchell, L. B., Macle, L., Stiell, I. G., Gladstone, D. J., McMurtry, M. S., Connolly, S. J., Cox, J. L., Dorian, P., et al. (2014) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2014.08.001 · Cited by 478
Incidence, outcome, risk factors, and long-term prognosis of cryptogenic transient ischaemic attack and ischaemic stroke: a population-based study
Li, L.-X., Yiin, G., Geraghty, O., Schulz, U., Küker, W., Mehta, Z., & Rothwell, P. (2015) · Lancet Neurology · doi:10.1016/s1474-4422(15)00132-5 · Cited by 397
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Kamel, H., & Healey, J. S. (2017) · Circulation Research · doi:10.1161/circresaha.116.308407 · Cited by 456
Randomized trial of atrial arrhythmia monitoring to guide anticoagulation in patients with implanted defibrillator and cardiac resynchronization devices
Martin, D. T., BERSOHN, M. M., Waldo, A. L., Wathen, M. S., Choucair, W. K., Lip, G. Y. H., Ip, J. E., Holcomb, R. G., Akar, J. G., & Halperin, J. L. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv115 · Cited by 361
Perioperative atrial fibrillation and the long-term risk of ischemic stroke
Gialdini, G., Nearing, K., Bhave, P. D., Bonuccelli, U., Iadecola, C., Healey, J. S., & Kamel, H. (2014) · JAMA · doi:10.1001/jama.2014.9143 · Cited by 355
Atrial cardiomyopathy revisited—evolution of a concept: a clinical consensus statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), the Asian Pacific Heart Rhythm Society (APHRS), and the Latin American Heart Rhythm Society (LAHRS)
Goette, A., Corradi, D., Dobrev, D., Aguinaga, L., Cabrera, J. Á., Chugh, S. S., de Groot, J. R., Soulat-Dufour, L., Fenelon, G., Hatem, S. N., et al. (2024) · EP Europace · doi:10.1093/europace/euae204 · Cited by 370
“115 Two additional clinical studies (TRENDS and IMPACT), have found similar results to those of the ASSERT study on the lack of temporal correlation be-tween AF episodes and cerebrovascular events.”
2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation
Tzeis, S. E., Gerstenfeld, E. P., Kalman, J. M., Saad, E., Shamloo, A. S., Andrade, J. G., Barbhaiya, C. R., Baykaner, T., Bovéda, S., Calkins, H. G., et al. (2024) · Heart Rhythm · doi:10.1016/j.hrthm.2024.03.017 · Cited by 323
Rationale and design of the Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation (ARTESiA) trial
Lópes, R. D., Alings, M., Connolly, S. J., Beresh, H., Granger, C. B., Mazuecos, J. B., Boriani, G., Nielsen, J. C., Conen, D., Hohnloser, S. H., et al. (2017) · American Heart Journal · doi:10.1016/j.ahj.2017.04.008 · Cited by 288
Atrial Failure as a Clinical Entity
Bisbal, F., Baranchuk, A. M., D, E. B. M., Bayés‐Genís, A., & Bayés‐Genís, A. (2020) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2019.11.013 · Cited by 286
“of AF episodes and stroke suggests that AF could be a marker of atrial myopathy rather than a cause of thrombus formation (27).”
Background
Subclinical device-detected atrial fibrillation and stroke risk: a systematic review and meta-analysis
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Screening for atrial fibrillation: a European Heart Rhythm Association (EHRA) consensus document endorsed by the Heart Rhythm Society (HRS), Asia Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulación Cardíaca y Electrofisiología (SOLAECE).
Mairesse, G., Moran, P., van Gelder, I. V., Elsner, C., Rosenqvist, M., Mant, J., Banerjee, A., Gorenek, B., Brachmann, J., Varma, N., et al. (2018) · Europace · doi:10.1093/europace/eux177 · Cited by 191
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Görenek, B., Bax, J. J., Boriani, G., Chen, S., Dagres, N., Glotzer, T. V., Healey, J. S., Israel, C. W., Kudaiberdieva, G., Levin, L., et al. (2017) · EP Europace · doi:10.1093/europace/eux163 · Cited by 249
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Schnabel, R. B., Hæusler, K. G., Healey, J. S., Freedman, B., Boriani, G., Brachmann, J., Brandes, A., Bustamante, A., Casadei, B., Crijns, H. J. G. M., et al. (2019) · Circulation · doi:10.1161/circulationaha.119.040267 · Cited by 248
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Shen, M. J., Arora, R., & Jalife, J. (2019) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2019.05.005 · Cited by 243
“their first AF event after their strokes (5).”
Background
Atrial fibrillation
Lip, G. Y. H., Fauchier, L., Freedman, S. B., Gelder, I. C. V., Natale, A., Gianni, C., Nattel, S., Potpara, T., Rienstra, M., Tse, H., et al. (2016) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2016.16 · Cited by 248
2018 Focused Update of the Canadian Cardiovascular Society Guidelines for the Management of Atrial Fibrillation
Andrade, J. G., Verma, A., Mitchell, L. B., Parkash, R., Leblanc, K., Atzema, C. L., Healey, J. S., Bell, A., Cairns, J. A., Connolly, S. J., et al. (2018) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2018.08.026 · Cited by 242
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Guichard, J.-B., & Nattel, S. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.06.033 · Cited by 226
Hypertension and cardiac arrhythmias: a consensus document from the European Heart Rhythm Association (EHRA) and ESC Council on Hypertension, endorsed by the Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS) and Sociedad Latinoamericana de Estimulación Cardíaca y Electrofisiología (SOLEACE)
Lip, G. Y. H., Coca, A., Kahan, T., Boriani, G., Manolis, A. S., Olsen, M. H., Oto, A., Potpara, T., Steffel, J., Marín, F. R., et al. (2017) · EP Europace · doi:10.1093/europace/eux091 · Cited by 233
Fibrotic Atrial Cardiomyopathy, Atrial Fibrillation, and Thromboembolism
Hirsh, B. J., Copeland-Halperin, R. S., & Halperin, J. L. (2015) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2015.03.557 · Cited by 214
Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation
Pluymaekers, N. A. H. A., Dudink, E. A. M. P., LUERMANS, J. G. L. M., Meeder, J. G., Lenderink, T., Widdershoven, J. W. M. G., Bucx, J. J. J., Rienstra, M., Kamp, O., van Opstal, J. M., et al. (2019) · New England Journal of Medicine · doi:10.1056/nejmoa1900353 · Cited by 220
Atrial Premature Beats Predict Atrial Fibrillation in Cryptogenic Stroke
Gladstone, D. J., Dorian, P., Spring, M., Panzov, V., Mamdani, M., Healey, J. S., Thorpe, K. E., Aviv, R. I., Boyle, K., Blakely, J. A., et al. (2015) · Stroke · doi:10.1161/strokeaha.115.008714 · Cited by 200
Atrial Fibrillation Burden and Short-Term Risk of Stroke: Case-Crossover Analysis of Continuously Recorded Heart Rhythm From Cardiac Electronic Implanted Devices
Turakhia, M. P., Ziegler, P. D., Schmitt, S. K., Chang, Y., Fan, J., Than, C. T., Keung, E. K., & Singer, D. E. (2015) · Circulation: Arrhythmia and Electrophysiology · doi:10.1161/circep.114.003057 · Cited by 197
Silent atrial fibrillation: epidemiology, diagnosis, and clinical impact
Dilaveris, P., & Kennedy, H. (2017) · Clinical Cardiology · doi:10.1002/clc.22667 · Cited by 175
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King, J. B., Azadani, P. N., Suksaranjit, P., Bress, A. P., Witt, D. M., Han, F. T., Chelu, M. G., Silver, M. A., BISKUPIAK, J. E., Wilson, B. D., et al. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.07.758 · Cited by 195
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Brachmann, J., Morillo, C. A., Sanna, T., Lazzaro, V. D., Diener, H., Bernstein, R. A., Rymer, M., Ziegler, P., Liu, S., & PASSMAN, R. S. (2016) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.115.003333 · Cited by 183
Atrial Cardiopathy: A Broadened Concept of Left Atrial Thromboembolism Beyond Atrial Fibrillation
Kamel, H., Okin, P. M., Longstreth, W. T., Elkind, M. S. V., & Soliman, E. Z. (2015) · Future Cardiology · doi:10.2217/fca.15.22 · Cited by 175
Left Atrial Appendage Function and Stroke Risk
Yaghi, S. R., Song, C., Gray, W. A., Furie, K. L., Elkind, M. S. V., & Kamel, H. (2015) · Stroke · doi:10.1161/strokeaha.115.011273 · Cited by 176
New-Onset Atrial Fibrillation in the Critically Ill*
Moss, T. J., Calland, J. F., Enfield, K. B., Gomez-Manjarres, D. C., Ruminski, C., Dimarco, J., Lake, D. E., & Moorman, J. R. (2017) · Critical Care Medicine · doi:10.1097/ccm.0000000000002325 · Cited by 172
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Noseworthy, P. A., Kaufman, E. S., Chen, L. Y., Chung, M. K., Elkind, M. S. V., Joglar, J. A., Leal, M. A., McCabe, P. J., Pokorney, S. D., Yao, X., et al. (2019) · Circulation · doi:10.1161/cir.0000000000000740 · Cited by 171
Atrial fibrillation and stroke prevention: 25 years of research at EP Europace journal
Lip, G. Y. H., Proietti, M., Potpara, T., MANSOUR, M. C., Savelieva, I., Tse, H., Goette, A., Camm, A. J., Blomström‐Lundqvist, C., Gupta, D., et al. (2023) · EP Europace · doi:10.1093/europace/euad226 · Cited by 176
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Kamel, H., Bartz, T. M., Elkind, M. S. V., Okin, P. M., Thacker, E. L., Patton, K. K., Stein, P. K., deFilippi, C. R., Gottesman, R. F., Heckbert, S. R., et al. (2018) · Stroke · doi:10.1161/strokeaha.117.020059 · Cited by 164
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“…DDAF episodes and stroke in ASSERT (Asymptomatic Atrial Fibrillation and Stroke Evaluation in Pacemaker Patients and the Atrial Fibrillation Reduction Atrial Pacing Trial) 111 or in LOOP, 48 although a small increase in AF burden can be detected in the month prior to a stroke in patients with DDAF.”
Background
Clinical Implications of Brief Device-Detected Atrial Tachyarrhythmias in a Cardiac Rhythm Management Device Population
Swiryn, S., Orlov, M. V., Benditt, D. G., Dimarco, J., Lloyd‐Jones, D. M., Karst, E., Qu, F., Slawsky, M., Turkel, M., & Waldo, A. L. (2016) · Circulation · doi:10.1161/circulationaha.115.020252 · Cited by 154
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AKOUM, N. W., Mahnkopf, C., Kholmovski, E. G., Brachmann, J., & MARROUCHE, N. F. (2017) · EP Europace · doi:10.1093/europace/eux260 · Cited by 154
2018 Korean Guideline of Atrial Fibrillation Management
Joung, B., Lee, J., Lee, K. H., Kim, T., Choi, E., Lim, W., Kang, K., Uhm, J., Lim, H. E., Park, J., et al. (2018) · Korean Circulation Journal · doi:10.4070/kcj.2018.0339 · Cited by 157
Atrial Fibrillation Detected After Stroke and Transient Ischemic Attack: A Novel Clinical Concept Challenging Current Views
Sposato, L. A., Chaturvedi, S., Hsieh, C., Morillo, C. A., & Kamel, H. (2022) · Stroke · doi:10.1161/strokeaha.121.034777 · Cited by 146
Electrocardiographic left atrial abnormality and stroke subtype in the atherosclerosis risk in communities study
Kamel, H., O’Neal, W. T., Okin, P. M., Loehr, L. R., Alonso, Á., & Soliman, E. Z. (2015) · Annals of Neurology · doi:10.1002/ana.24482 · Cited by 135
Electrocardiographic Left Atrial Abnormality and Risk of Stroke
Kamel, H., Hunter, M. D., Moon, Y. P., Yaghi, S. R., Cheung, K., Tullio, M. R. D., Okin, P. M., Sacco, R. L., Soliman, E. Z., & Elkind, M. S. V. (2015) · Stroke · doi:10.1161/strokeaha.115.009989 · Cited by 132
P-Wave Indices and Risk of Ischemic Stroke
He, J., Tse, G., Korantzopoulos, P. G., Letsas, Κ. P., Ali‐Hasan‐Al‐Saegh, S., Kamel, H., Li, G., Lip, G. Y. H., & Liu, T. (2017) · Stroke · doi:10.1161/strokeaha.117.017293 · Cited by 131
Atrial fibrillation and stroke
Choi, S. E., Sagris, D., Hill, A. M., Lip, G. Y. H., & Abdul‐Rahim, A. H. (2022) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2023.2160319 · Cited by 142
Mental Stress and Cardiovascular Health—Part I
Vancheri, F., Longo, G., Vancheri, E., & Henein, M. Y. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11123353 · Cited by 147
Spotlight on the 2024 ESC/EACTS management of atrial fibrillation guidelines: 10 novel key aspects
Rienstra, M., Tzeis, S., Bunting, K. V., Caso, V., Crijns, H. J. G. M., De Potter, T. J. R., Sanders, P., Svennberg, E., Casado-Arroyo, R., Dwight, J., et al. (2024) · Europace · doi:10.1093/europace/euae298 · Cited by 128
Comprehensive Evaluation of Rhythm Monitoring Strategies in Screening for Atrial Fibrillation
Diederichsen, S. Z., Haugan, K., Kronborg, C., Graff, C., Højberg, S., Køber, L., Krieger, D. W., Holst, A. G., Nielsen, J. B., Brandes, A., et al. (2020) · Circulation · doi:10.1161/circulationaha.119.044407 · Cited by 127
Etiologic classification of ischemic stroke: Where do we stand?
Radu, R. A., Terecoasă, E., Bajenaru, O. A., & Tiu, C. (2017) · Clinical Neurology and Neurosurgery · doi:10.1016/j.clineuro.2017.05.019 · Cited by 129
Tailoring the Approach to Embolic Stroke of Undetermined Source
Kamel, H., Merkler, A. E., Iadecola, C., Gupta, A. K., & Navi, B. B. (2019) · JAMA Neurology · doi:10.1001/jamaneurol.2019.0591 · Cited by 126
Management of atrial high-rate episodes detected by cardiac implanted electronic devices
Freedman, B., Boriani, G., Glotzer, T. V., Healey, J. S., Kirchhof, P. F., & Potpara, T. (2017) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2017.94 · Cited by 120
Atrial Fibrillation Occurring During Acute Hospitalization: A Scientific Statement From the American Heart Association
Chyou, J. Y., Barkoudah, E., Dukes, J. W., Goldstein, L. B., Joglar, J. A., Lee, A. M., Lubitz, S. A., Marill, K. A., Sneed, K., Streur, M. M., et al. (2023) · Circulation · doi:10.1161/cir.0000000000001133 · Cited by 127
Left Atrial Mechanical Function and Incident Ischemic Cerebrovascular Events Independent of AF
Habibi, M., Zareian, M., Ambale‐Venkatesh, B., Samiei, S., Imai, M., Wu, C. O., Launer, L. J., Shea, S., Gottesman, R. F., Heckbert, S. R., et al. (2019) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2019.02.021 · Cited by 121
Management of asymptomatic arrhythmias: a European Heart Rhythm Association (EHRA) consensus document, endorsed by the Heart Failure Association (HFA), Heart Rhythm Society (HRS), Asia Pacific Heart Rhythm Society (APHRS), Cardiac Arrhythmia Society of Southern Africa (CASSA), and Latin America Heart Rhythm Society (LAHRS)
Arnar, D. O., Mairesse, G. H., Boriani, G., Calkins, H. G., Chin, A., Coats, A. J. S., Deharo, J., Svendsen, J. H., Heidbüchel, H., Isa, R., et al. (2019) · EP Europace · doi:10.1093/europace/euz046 · Cited by 127
Integrating new approaches to atrial fibrillation management: the 6th AFNET/EHRA Consensus Conference
Kotecha, D., BREITHARDT, G. E., Camm, A. J., Lip, G. Y. H., Schotten, U., Ahlsson, A., Arnar, D. O., Atar, D., Auricchio, A., Bax, J. J., et al. (2018) · EP Europace · doi:10.1093/europace/eux318 · Cited by 117
Targeted Anticoagulation for Atrial Fibrillation Guided by Continuous Rhythm Assessment With an Insertable Cardiac Monitor: The Rhythm Evaluation for Anticoagulation With Continuous Monitoring (REACT.COM) Pilot Study
PASSMAN, R., LEONG‐SIT, P., ANDREI, A., HUSKIN, A., TOMSON, T. T., BERNSTEIN, R., ELLIS, E., WAKS, J. W., & ZIMETBAUM, P. (2016) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.12864 · Cited by 115
Review and update of the concept of embolic stroke of undetermined source
Diener, H., Easton, J. D., Hart, R. G., Kasner, S. E., Kamel, H., & Ntaios, G. (2022) · Nature Reviews Neurology · doi:10.1038/s41582-022-00663-4 · Cited by 115
Characterization, Pathogenesis, and Clinical Implications of Inflammation‐Related Atrial Myopathy as an Important Cause of Atrial Fibrillation
Packer, M. (2020) · Journal of the American Heart Association · doi:10.1161/jaha.119.015343 · Cited by 110
Bioinformatic gene analysis for potential biomarkers and therapeutic targets of atrial fibrillation-related stroke
Zou, R., Zhang, D., Lv, L., Shi, W., Song, Z., Yi, B., Lai, B., Chen, Q., Yang, S., & Hua, P. (2019) · Journal of Translational Medicine · doi:10.1186/s12967-019-1790-x · Cited by 109
Atrial cardiopathy: a mechanism of cryptogenic stroke
Yaghi, S. R., Kamel, H., & Elkind, M. S. V. (2017) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2017.1355238 · Cited by 109
Demonstration of Patient-Specific Simulations to Assess Left Atrial Appendage Thrombogenesis Risk
García‐Villalba, M., Rossini, L., Gonzalo, A., Vigneault, D. M., Martínez‐Legazpi, P., Durán, E., Flores, Ó., Bermejo, J., McVeigh, E. R., Kahn, A. M., et al. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.596596 · Cited by 107
Atrial high-rate episodes and stroke prevention
Camm, A. J., SIMANTIRAKIS, E. N., Goette, A., Lip, G. Y. H., Vardas, P. E., Calvert, M., CHLOUVERAKIS, G. I., Diener, H., & Kirchhof, P. F. (2016) · EP Europace · doi:10.1093/europace/euw279 · Cited by 104
Temporal Association Between Episodes of Atrial Fibrillation and Risk of Ischemic Stroke
Singer, D. E., Ziegler, P., Koehler, J. L., Sarkar, S., & PASSMAN, R. S. (2021) · JAMA Cardiology · doi:10.1001/jamacardio.2021.3702 · Cited by 103
Rivaroxaban for secondary stroke prevention in patients with embolic strokes of undetermined source: Design of the NAVIGATE ESUS randomized trial
Hart, R. G., Sharma, M., Mundl, H., Shoamanesh, A., Kasner, S. E., Berkowitz, S. D., Paré, G., Kirsch, B., Pogue, J., Pater, C., et al. (2016) · European Stroke Journal · doi:10.1177/2396987316663049 · Cited by 96
“Further, short episodes of atrial fibrillation are not necessarily temporally associated with stroke risk, raising further doubt about their relevance to the pathogenesis of stroke.(25) For NAVIGATE ESUS eligibility, screening for covert paroxysmal atrial fibrillation with 20h of cardiac rhythm monitoring is required,…”
Background
Optimizing indices of atrial fibrillation susceptibility and burden to evaluate atrial fibrillation severity, risk and outcomes
Boriani, G., Vitolo, M., Diemberger, I., Proietti, M., Valenti, A. C., Malavasi, V. L., & Lip, G. Y. H. (2021) · Cardiovascular Research · doi:10.1093/cvr/cvab147 · Cited by 105
A Computational Framework for Personalized Blood Flow Analysis in the Human Left Atrium
Otani, T., Alissa, A., Pourmorteza, A., McVeigh, E. R., Wada, S., & Ashikaga, H. (2016) · Annals of Biomedical Engineering · doi:10.1007/s10439-016-1590-x · Cited by 94
The Optimal Anti-Coagulation for Enhanced-Risk Patients Post–Catheter Ablation for Atrial Fibrillation (OCEAN) trial
Verma, A., Ha, A. C. T., Kirchhof, P. F., Hindricks, G., Healey, J. S., Hill, M. D., Sharma, M., Wyse, D. G., Champagne, J., Essebag, V., et al. (2017) · American Heart Journal · doi:10.1016/j.ahj.2017.12.007 · Cited by 91
Apixaban versus Aspirin for Embolic Stroke of Undetermined Source
Geisler, T., Keller, T., Martus, P., Poli, K., Serna-Higuita, L. M., Schreieck, J., Gawaz, M., Tünnerhoff, J., Bombach, P., Nägele, T., et al. (2023) · NEJM Evidence · doi:10.1056/evidoa2300235 · Cited by 89
Embolic Strokes of Unknown Source and Cryptogenic Stroke: Implications in Clinical Practice
Nouh, A. M., Hussain, M., Mehta, T., & Yaghi, S. R. (2016) · Frontiers in Neurology · doi:10.3389/fneur.2016.00037 · Cited by 89
Stroke as the First Manifestation of Atrial Fibrillation
Jaakkola, J., Mustonen, P. E., Kiviniemi, T., Hartikainen, J. E. K., Palomäki, A., Hartikainen, P. H., Nuotio, I. O., Ylitalo, A., & Airaksinen, J. K. E. (2016) · PLoS ONE · doi:10.1371/journal.pone.0168010 · Cited by 84
Atrial fibrillation burden and atrial fibrillation type: Clinical significance and impact on the risk of stroke and decision making for long-term anticoagulation
Boriani, G., & Pettorelli, D. (2016) · Vascular Pharmacology · doi:10.1016/j.vph.2016.03.006 · Cited by 85
Atrial Fibrillation and Endothelial Dysfunction
Corban, M., Toya, T., Ahmad, A., Lerman, L. O., Lee, H.-C., & Lerman, A. (2021) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2020.11.005 · Cited by 87
Atrial Fibrillation Burden Signature and Near-Term Prediction of Stroke
Han, L., Askari, M., Altman, R. B., Schmitt, S. K., Fan, J., Bentley, J., Narayan, S. M., & Turakhia, M. P. (2019) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.118.005595 · Cited by 79
Towards a new classification of atrial fibrillation detected after a stroke or a transient ischaemic attack
Sposato, L. A., Field, T. S., Schnabel, R. B., Wachter, R., Andrade, J. G., & Hill, M. D. (2023) · The Lancet Neurology · doi:10.1016/s1474-4422(23)00326-5 · Cited by 78
Atrial Cardiopathy and Cryptogenic Stroke: A Cross-sectional Pilot Study
Yaghi, S. R., Boehme, A. K., Hazan, R., Hod, E. A., Canaan, A., Andrews, H., Kamel, H., Marshall, R. S., & Elkind, M. S. V. (2015) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2015.09.001 · Cited by 78
EACVI recommendations on cardiovascular imaging for the detection of embolic sources: endorsed by the Canadian Society of Echocardiography
Cohen, A. A., Donal, E., Delgado, V., Pepi, M., Tsang, T. S. M., Gerber, B. L., Soulat-Dufour, L., Habib, G., Lancellotti, P., Evangelista, A., et al. (2021) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jeab008 · Cited by 76
Atrial fibrillation detected by continuous electrocardiographic monitoring using implantable loop recorder to prevent stroke in individuals at risk (the LOOP study): Rationale and design of a large randomized controlled trial
Diederichsen, S. Z., Haugan, K., Køber, L., Højberg, S., Brandes, A., Kronborg, C., Graff, C., Holst, A. G., Nielsen, J. B., Krieger, D. W., et al. (2017) · American Heart Journal · doi:10.1016/j.ahj.2017.02.017 · Cited by 74
Atrial high-rate episodes: prevalence, stroke risk, implications for management, and clinical gaps in evidence
Bertaglia, E., Blank, B., Blomström‐Lundqvist, C., Brandes, A., Cabanelas, N., Dan, G. A., Dichtl, W., Goette, A., de Groot, J. R., Lubiński, A., et al. (2019) · EP Europace · doi:10.1093/europace/euz172 · Cited by 72
2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation
Tzeis, S. E., Gerstenfeld, E. P., Kalman, J. M., Saad, E., Shamloo, A. S., Andrade, J. G., Barbhaiya, C. R., Baykaner, T., Bovéda, S., Calkins, H. G., et al. (2024) · Journal of Arrhythmia · doi:10.1002/joa3.13082 · Cited by 76
Early detection of atrial high rate episodes predicts atrial fibrillation and thromboembolic events in patients with cardiac resynchronization therapy
Witt, C. T., Kronborg, M. B., Nohr, E. A., Mortensen, P. T., Gerdes, C., & Nielsen, J. C. (2015) · Heart Rhythm · doi:10.1016/j.hrthm.2015.07.007 · Cited by 72
The Atrium and Embolic Stroke
Sajeev, J., Kalman, J. M., Dewey, H. M., Cooke, J. C., & Teh, A. W. (2020) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2019.12.013 · Cited by 72
Change in left atrial function predicts incident atrial fibrillation: the Multi-Ethnic Study of Atherosclerosis
Lim, D. J., Ambale‐Venkatesh, B., Ostovaneh, M. R., Zghaib, T., Ashikaga, H., Wu, C. O., Watson, K. E., Hughes, T. M., Shea, S., Heckbert, S. R., et al. (2019) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jez176 · Cited by 72
Atrial cardiopathy in patients with embolic strokes of unknown source and other stroke etiologies
Jalini, S., Rajalingam, R., Nisenbaum, R. A., Javier, A. D., Woo, A., & Pikula, A. (2018) · Neurology · doi:10.1212/wnl.0000000000006748 · Cited by 69
Cryptogenic stroke and atrial fibrillation.
Malnick, S. D. H., Somin, M., & Goland, S. (2014) · PubMed · doi:10.1056/nejmc1409495 · Cited by 42

Authors: Brambatti, M., Connolly, S. J., Gold, M. R., Morillo, C. A., Capucci, A., Muto, C., Lau, C. P., Van Gelder, I. C., Hohnloser, S. H., Carlson, M., Fain, E., Nakamya, J., Mairesse, G. H., Halytska, M., Deng, W. Q., Israel, C. W., & Healey, J. S.
Affiliations: Goethe University Frankfurt (DE)
From the Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada (M.B., S.J.C., C.A.M., J.N., M.H., W.Q.D., J.S.H.); Clinica di Cardiologia, Università Politecnica delle Marche, Ancona, Italy (M.B., A.C.); Medical University of South Carolina, Charleston (M.R.G.); Cardiology Department, Loreto Mare, Napoli, Italy (C.M.); Queen Mary Hospital, Department of Medicine, University of Hong Kong, Hong Kong, China (C.P.L.); University of Groningen, University Medical Center...
ORCID: Brambatti, Michela
Connolly, Stuart J.
Gold, Michael R.
Morillo, Carlos A.
Capucci, Alessandro
Muto, Carmine
Lau, Chu P.
Hohnloser, Stefan H.
Fain, Eric
Mairesse, Georges H.
Deng, Wei Q.
Israel, Carsten W
Healey, Jeff S.
Venue: Circulation
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2014-05-27
Volume: 129
Issue: 21
Pages: 2094-2099
ISSN: 0009-7322 (ISSN-L)
1524-4539
DOI: 10.1161/circulationaha.113.007825
OpenAlex: W2024497977
Cited by: 676
References: 31
Citations by year: 2026: 21 · 2025: 35 · 2024: 52 · 2023: 66 · 2022: 62 · 2021: 67 · 2020: 55 · 2019: 63 · 2018: 57 · 2017: 66 · 2016: 58 · 2015: 57 · 2014: 15
FWCI: 44.81
Type: journal article
Language: en
Open access: green
www.openaccessrepository.it
Licence: other-oa
Locations: Circulation (publishedVersion)
PubMed (publishedVersion)
Università Politecnica delle Marche (Università Politecnica delle Marche) (submittedVersion)
University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
INFM-OAR (INFN Catania) (submittedVersion, other-oa)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cardiovascular and Diving-Related Complications
Keywords: subclinical atrial fibrillation, stroke, systemic embolism, implantable cardioverter-defibrillator, cardiac pacemaker, temporal relations, asymptomatic atrial fibrillation, hypertension
MeSH terms: Aged, Aged, 80 and over, Atrial Fibrillation, Embolism, Female, Follow-Up Studies, Humans, Male, Pacemaker, Artificial, Prospective Studies, Risk Factors, Time Factors, Stroke

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Temporal Relationship Between Subclinical Atrial Fibrillation and Embolic Events

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