Spotlight on the 2024 ESC/EACTS management of atrial fibrillation guidelines: 10 novel key aspects

2021 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure

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Should We STOP Angiotensin Converting Enzyme Inhibitors/Angiotensin Receptor Blockers in Advanced Kidney Disease?

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Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019

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Atrial fibrillation as an independent risk factor for stroke: the Framingham study

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Angiotensin-neprilysin inhibition versus enalapril in heart failure

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ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012

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2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS

Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw210 · Cited by 6,418 · see citing works

Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials

Ruff, C. T., Giugliano, R. P., Braunwald, E., Hoffman, E. B., Deenadayalu, N., Ezekowitz, M. D., Camm, A. J., Weitz, J. I., Lewis, B. S., Parkhomenko, A., et al. (2014) · The Lancet · doi:10.1016/s0140-6736(13)62343-0 · Cited by 5,051 · see citing works

Empagliflozin in heart failure with a preserved ejection fraction

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Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation

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2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS.

Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castellá, M., Diener, H., Heidbuchel, H., Hendriks, J., et al. (2016) · Europace · doi:10.1093/europace/euw295 · Cited by 4,465 · see citing works

2024 ESC Guidelines for the management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)

Gelder, I. C. V., Rienstra, M., Bunting, K. V., Casado-Arroyo, R., Caso, V., Crijns, H. J. G. M., Potter, T. J. R. D., Dwight, J., Guasti, L., Hanke, T., et al. (2024) · European Heart Journal · doi:10.1093/eurheartj/ehae176 · Cited by 3,338 · see citing works

Eplerenone in patients with systolic heart failure and mild symptoms

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2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association of Cardio-Thoracic Surgery (EACTS).

Hindricks, G., Potpara, T., Dagres, N., Arbelo, E., Bax, J., Blomström-Lundqvist, C., Boriani, G., Castellá, M., Dan, G., Dilaveris, P. E., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehaa612 · Cited by 2,605 · see citing works

Catheter Ablation for Atrial Fibrillation with Heart Failure

MARROUCHE, N. F., Brachmann, J., Andresen, D., Siebels, J., Boersma, L. V. A., Jordaens, L. J. L. M., Merkely, B. P., Pokushalov, E., Sanders, P., Proff, J., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1707855 · Cited by 2,514 · see citing works

Apixaban in patients with atrial fibrillation

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Early Rhythm-Control Therapy in Patients with Atrial Fibrillation

Kirchhof, P. F., Camm, A. J., Goette, A., Brandes, A., Eckardt, L., Elvan, A., Fetsch, T., Gelder, I. C. V., Haase, D., Haegeli, L., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2019422 · Cited by 2,227 · see citing works

Sotagliflozin in patients with diabetes and recent worsening heart failure

Bhatt, D. L., Szarek, M., Steg, P. G., Cannon, C. P., Leiter, L. A., McGuire, D. K., Lewis, J. B., Riddle, M. C., Voors, A. A., Metra, M., et al. (2021) · New England Journal of Medicine · doi:10.1056/nejmoa2030183 · Cited by 1,868 · see citing works

Comparison of Antiarrhythmic Drug Therapy and Radiofrequency Catheter Ablation in Patients With Paroxysmal Atrial Fibrillation: A Randomized Controlled Trial

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Radiofrequency Ablation vs Antiarrhythmic Drugs as First-line Treatment of Symptomatic Atrial Fibrillation: A Randomized Trial

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Long-Term Effect of Goal-Directed Weight Management in an Atrial Fibrillation Cohort

Pathak, R. K., Middeldorp, M. E., Meredith, M., Mehta, A. B., Mahajan, R., Wong, C. X., Twomey, D., Elliott, A. D., Kalman, J. M., Abhayaratna, W. P., et al. (2015) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2015.03.002 · Cited by 1,036 · see citing works

Use of Transesophageal Echocardiography to Guide Cardioversion in Patients with Atrial Fibrillation

Klein, A. L., Grimm, R. A., Murray, R. D., Apperson-Hansen, C., ASINGER, R. W., Black, I. W., Davidoff, R., Erbel, R., Halperin, J. L., Orsinelli, D. A., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200105103441901 · Cited by 952 · see citing works

Catheter Ablation Versus Antiarrhythmic Drugs for Atrial Fibrillation

Jaı̈s, P., CAUCHEMEZ, B., Macle, L., Daoud, E. G., Khairy, P., Subbiah, R. N., Hocini, M., Extramiana, F., Sacher, F., Bordachar, P., et al. (2008) · Circulation · doi:10.1161/circulationaha.108.772582 · Cited by 889 · see citing works

Ablation Versus Amiodarone for Treatment of Persistent Atrial Fibrillation in Patients With Congestive Heart Failure and an Implanted Device

Biase, L. D., Mohanty, P. K., Mohanty, S., Santangeli, P., Trivedi, C. G., Lakkireddy, D., Reddy, M., Jaı̈s, P., Themistoclakis, S., Russo, A. D., et al. (2016) · Circulation · doi:10.1161/circulationaha.115.019406 · Cited by 880 · see citing works

Cryoablation or Drug Therapy for Initial Treatment of Atrial Fibrillation

Andrade, J. G., Wells, G. A., Deyell, M. W., Bennett, M. T., Essebag, V., Champagne, J., Roux, J.-F., Yung, D., Skanes, A. C., Khaykin, Y., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2029980 · Cited by 841 · see citing works

Effect of Weight Reduction and Cardiometabolic Risk Factor Management on Symptom Burden and Severity in Patients With Atrial Fibrillation: A Randomized Clinical Trial

Abed, H. S., Wittert, G. A., Leong, D. P., Shirazi, M. G., Bahrami, B., Middeldorp, M. E., Lorimer, M. F., Lau, D. H., Antic, N. A., Brooks, A. G., et al. (2013) · JAMA · doi:10.1001/jama.2013.280521 · Cited by 776 · see citing works

Left Atrial Appendage Occlusion during Cardiac Surgery to Prevent Stroke

Whitlock, R. P., Belley‐Côté, E. P., Paparella, D., Healey, J. S., Brady, K., Sharma, M., Reents, W., Budera, P., Baddour, A. J., Fila, P., et al. (2021) · New England Journal of Medicine · doi:10.1056/nejmoa2101897 · Cited by 741 · see citing works

Radiofrequency ablation as initial therapy in paroxysmal atrial fibrillation

Cosedis Nielsen, J., Johannessen, A., Raatikainen, P., Hindricks, G., Walfridsson, H., Kongstad, O., Pehrson, S., Englund, A., Hartikainen, J., Mortensen, L. S., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1113566 · Cited by 720 · see citing works

2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation

Tzeis, S. E., Gerstenfeld, E. P., Kalman, J. M., Saad, E., Shamloo, A. S., Andrade, J. G., Barbhaiya, C. R., Baykaner, T., Bovéda, S., Calkins, H. G., et al. (2024) · EP Europace · doi:10.1093/europace/euae043 · Cited by 692 · see citing works

Temporal relationship between subclinical atrial fibrillation and embolic events

Brambatti, M., Connolly, S. J., Gold, M. R., Morillo, C. A., Capucci, A., Muto, C., Lau, C. P., Van Gelder, I. C., Hohnloser, S. H., Carlson, M., et al. (2014) · Circulation · doi:10.1161/circulationaha.113.007825 · Cited by 676 · see citing works

Radiofrequency Ablation vs Antiarrhythmic Drugs as First-Line Treatment of Paroxysmal Atrial Fibrillation (RAAFT-2): A Randomized Trial

Morillo, C. A., Verma, A., Connolly, S. J., Kuck, K. H., Nair, G. M., Champagne, J., Sterns, L. D., Beresh, H., Healey, J. S., Natale, A., et al. (2014) · JAMA · doi:10.1001/jama.2014.467 · Cited by 667 · see citing works

Cryoballoon Ablation as Initial Therapy for Atrial Fibrillation

Wazni, O. M., Dandamudi, G., Sood, N. A., HOYT, R. H., Tyler, J. D., Durrani, S., Niebauer, M. J., Makati, K. J., Halperin, B. D., Gauri, A. J., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2029554 · Cited by 656 · see citing works

Efficacy of β blockers in patients with heart failure plus atrial fibrillation: an individual-patient data meta-analysis

Kotecha, D., Holmes, J., Krum, H., Altman, D. G., Manzano, L., Cleland, J. G. F., Lip, G. Y. H., Coats, A. J. S., Andersson, B., Kirchhof, P., et al. (2014) · The Lancet · doi:10.1016/s0140-6736(14)61373-8 · Cited by 579 · see citing works

Atrial Fibrillation and Risk of Clinical Events in Chronic Heart Failure With and Without Left Ventricular Systolic Dysfunction

Olsson, L. G., Swedberg, K., Ducharme, A., Granger, C. B., Michelson, E. L., McMurray, J. J. V., Puu, M., Yusuf, S., & Pfeffer, M. A. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.01.060 · Cited by 574 · see citing works

Impact of CARDIOrespiratory FITness on Arrhythmia Recurrence in Obese Individuals With Atrial Fibrillation

Pathak, R. K., Elliott, A., Middeldorp, M. E., Meredith, M., Mehta, A. B., Mahajan, R., Hendriks, J. M. L., Twomey, D., Kalman, J. M., Abhayaratna, W. P., et al. (2015) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2015.06.488 · Cited by 544 · see citing works

A Randomized Controlled Trial of Catheter Ablation Versus Medical Treatment of Atrial Fibrillation in Heart Failure (The CAMTAF Trial)

Hunter, R. J., Berriman, T., Diab, I. G., Kamdar, R., Richmond, L., Baker, V., Goromonzi, F., Sawhney, V., Duncan, E. R., Page, S. P., et al. (2014) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.113.000806 · Cited by 504 · see citing works

Off-Label Dosing of Non-Vitamin K Antagonist Oral Anticoagulants and Adverse Outcomes

Steinberg, B. A., Shrader, P. J., Thomas, L. E., Ansell, J., Fonarow, G. C., Gersh, B. J., Kowey, P. R., Mahaffey, K. W., Naccarelli, G. V., Reiffel, J. A., et al. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.09.966 · Cited by 493 · see citing works

Non–Vitamin K Antagonist Oral Anticoagulant Dosing in Patients With Atrial Fibrillation and Renal Dysfunction

Yao, X., Shah, N. D., Sangaralingham, L. R., Gersh, B. J., & Noseworthy, P. A. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.03.600 · Cited by 469 · see citing works

Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation

Healey, J. S., Lópes, R. D., Granger, C. B., Alings, M., Rivard, L., McIntyre, W. F., Atar, D., Birnie, D. H., Boriani, G., Camm, A. J., et al. (2023) · New England Journal of Medicine · doi:10.1056/nejmoa2310234 · Cited by 460 · see citing works

Alcohol Abstinence in Drinkers with Atrial Fibrillation

Voskoboinik, A., Kalman, J. M., Silva, A. P. D., Nicholls, T., Costello, B. T., Nanayakkara, S., Prabhu, S., Stub, D. A., Azzopardi, S. M., Vizi, D., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa1817591 · Cited by 450 · see citing works

Treatment of Obstructive Sleep Apnea Reduces the Risk of Atrial Fibrillation Recurrence After Catheter Ablation

Fein, A. S., Shvilkin, A., Shah, D., Haffajee, C. I., Das, S., Kumar, K., Kramer, D. B., Zimetbaum, P. J., Buxton, A. E., Josephson, M. E., et al. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.03.052 · Cited by 447 · see citing works

Anticoagulation with Edoxaban in Patients with Atrial High-Rate Episodes

Kirchhof, P. F., Toennis, T., Goette, A., Camm, A. J., Diener, H., Becher, N., Bertaglia, E., Lundqvist, C. B., Borlich, M., Brandes, A., et al. (2023) · New England Journal of Medicine · doi:10.1056/nejmoa2303062 · Cited by 442 · see citing works

Catheter Ablation in End-Stage Heart Failure with Atrial Fibrillation

Sohns, C., Fox, H., MARROUCHE, N. F., Crijns, H. J. G. M., Costard‐Jäckle, A., Bergau, L., Hindricks, G., Dagres, N., Sossalla, S. T., Schramm, R., et al. (2023) · New England Journal of Medicine · doi:10.1056/nejmoa2306037 · Cited by 415 · see citing works

Catheter ablation vs. antiarrhythmic drug treatment of persistent atrial fibrillation: a multicentre, randomized, controlled trial (SARA study)

Mont, L., Bisbal, F., Hernández-Madrid, A., Pérez-Castellano, N., Viñolas, X., Arenal, A., Arribas, F., Fernández-Lozano, I., Bodegas, A., Cobos, A., et al. (2014) · European Heart Journal · doi:10.1093/eurheartj/eht457 · Cited by 394 · see citing works

PREVEntion and regReSsive Effect of weight-loss and risk factor modification on Atrial Fibrillation: the REVERSE-AF study

Middeldorp, M. E., Pathak, R. K., Meredith, M., Mehta, A. B., Elliott, A. D., Mahajan, R., Twomey, D. J., Gallagher, C., Hendriks, J., Linz, D., et al. (2018) · EP Europace · doi:10.1093/europace/euy117 · Cited by 393 · see citing works

Stroke in paroxysmal atrial fibrillation: report from the Stockholm Cohort of Atrial Fibrillation

Friberg, L., Hammar, N., & Rosenqvist, M. (2009) · European Heart Journal · doi:10.1093/eurheartj/ehn599 · Cited by 380 · see citing works

Rivaroxaban vs. vitamin K antagonists for cardioversion in atrial fibrillation

Cappato, R., Ezekowitz, M. D., Klein, A. L., Camm, A. J., Ma, C., Heuzey, J. L., Talajic, M. R., Scanavacca, M., Vardas, P. E., Kirchhof, P. F., et al. (2014) · European Heart Journal · doi:10.1093/eurheartj/ehu367 · Cited by 371 · see citing works

Clinical outcomes in systematic screening for atrial fibrillation (STROKESTOP): a multicentre, parallel group, unmasked, randomised controlled trial

Svennberg, E., Friberg, L., Frykman, V., Al‐Khalili, F., Engdahl, J., & Rosenqvist, M. (2021) · The Lancet · doi:10.1016/s0140-6736(21)01637-8 · Cited by 366 · see citing works

EUropean real-world outcomes with Pulsed field ablatiOn in patients with symptomatic atRIAl fibrillation: lessons from the multi-centre EU-PORIA registry

Schmidt, B., Bordignon, S., Neven, K. G. E. J., Reichlin, T., Blaauw, Y., Hansen, J., Adeliño, R., Ouss, A. J., Füting, A., Roten, L., et al. (2023) · EP Europace · doi:10.1093/europace/euad185 · Cited by 317 · see citing works

Targeted therapy of underlying conditions improves sinus rhythm maintenance in patients with persistent atrial fibrillation: results of the RACE 3 trial

Rienstra, M., Hobbelt, A. H., Alings, M., Tijssen, J. G. P., Smit, M. D., Brügemann, J., Geelhoed, B., Tieleman, R. G., Hillege, H. L., Tukkie, R., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehx739 · Cited by 313 · see citing works

2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation

Tzeis, S. E., Gerstenfeld, E. P., Kalman, J. M., Saad, E., Shamloo, A. S., Andrade, J. G., Barbhaiya, C. R., Baykaner, T., Bovéda, S., Calkins, H. G., et al. (2024) · Heart Rhythm · doi:10.1016/j.hrthm.2024.03.017 · Cited by 312 · see citing works

Recurrence of Atrial Fibrillation After Catheter Ablation or Antiarrhythmic Drug Therapy in the CABANA Trial

Poole, J. E., Bahnson, T. D., Monahan, K. H., Johnson, G. W., Rostami, H., Silverstein, A. P., Al‐Khalidi, H. R., Rosenberg, Y., Mark, D. B., Lee, K. L., et al. (2020) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2020.04.065 · Cited by 275 · see citing works

Global burden of atrial fibrillation/atrial flutter and its attributable risk factors from 1990 to 2021

Cheng, S., He, J., Han, Y., Han, S., Li, P., Liao, H., & Guo, J. (2024) · EP Europace · doi:10.1093/europace/euae195 · Cited by 269 · see citing works

Concomitant obstructive sleep apnea increases the recurrence of atrial fibrillation following radiofrequency catheter ablation of atrial fibrillation: Clinical impact of continuous positive airway pressure therapy

Naruse, Y., Tada, H., Satoh, M., Yanagihara, M., Tsuneoka, H., Hirata, Y., Ito, Y., Kuroki, K., Machino, T., Yamasaki, H., et al. (2013) · Heart Rhythm · doi:10.1016/j.hrthm.2012.11.015 · Cited by 267 · see citing works

Aerobic Interval Training Reduces the Burden of Atrial Fibrillation in the Short Term: A Randomized Trial

Malmo, V., Nes, B. M., Amundsen, B. H., Tjonna, A.-E., Stoylen, A., Rossvoll, O., Wisloff, U., & Loennechen, J. P. (2016) · Circulation · doi:10.1161/circulationaha.115.018220 · Cited by 263 · see citing works

Edoxaban versus enoxaparin–warfarin in patients undergoing cardioversion of atrial fibrillation (ENSURE-AF): a randomised, open-label, phase 3b trial

Goette, A., Merino, J. L., Ezekowitz, M. D., Zamoryakhin, D., Melino, M. R., Jin, J., Mercuri, M. F., GROSSO, M. A., Serrano-Fernandez, V., Al‐Saady, N., et al. (2016) · The Lancet · doi:10.1016/s0140-6736(16)31474-x · Cited by 249 · see citing works

Impact of obstructive sleep apnea and continuous positive airway pressure therapy on outcomes in patients with atrial fibrillation—Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF)

Holmqvist, F., Guan, N., Zhu, Z., Kowey, P. R., Allen, L. A., Fonarow, G. C., Hylek, E. M., Mahaffey, K. W., Freeman, J. V., Chang, P., et al. (2015) · American Heart Journal · doi:10.1016/j.ahj.2014.12.024 · Cited by 249 · see citing works

Long-Term Outcomes of Secondary Atrial Fibrillation in the Community

Lubitz, S. A., Yin, X., Rienstra, M., Schnabel, R. B., Walkey, A. J., Magnani, J. W., Rahman, F., McManus, D. D., Tadros, T. M., Levy, D. A., et al. (2015) · Circulation · doi:10.1161/circulationaha.114.014058 · Cited by 237 · see citing works

Symptoms and Functional Status of Patients With Atrial Fibrillation: State of the Art and Future Research Opportunities

Rienstra, M., Lubitz, S. A., Mahida, S., Magnani, J. W., Fontes, J. D., Sinner, M. F., Van Gelder, I. C., Ellinor, P. T., & Benjamin, E. J. (2012) · Circulation · doi:10.1161/circulationaha.111.069450 · Cited by 237 · see citing works

Cryoballoon ablation vs. antiarrhythmic drugs: first-line therapy for patients with paroxysmal atrial fibrillation

Kuniss, M., Pavlović, N., Velagić, V., Hermida, J. S., Healey, S., Arena, G., Badenco, N., Meyer, C. G., Chen, J., Iacopino, S., et al. (2021) · EP Europace · doi:10.1093/europace/euab029 · Cited by 232 · see citing works

Ischemic Stroke despite Oral Anticoagulant Therapy in Patients with Atrial Fibrillation

Seiffge, D. J., Marchis, G. M. D., Koga, M., Paciaroni, M., Wilson, D., Cappellari, M., Macha, K., Tsivgoulis, G. K., Ambler, G., Arihiro, S., et al. (2020) · Annals of Neurology · doi:10.1002/ana.25700 · Cited by 230 · see citing works

Analysis of Cause-Specific Mortality in the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) Study

Steinberg, J. S., Sadaniantz, A., Kron, J., Krahn, A. D., Denny, D. M., Daubert, J. P., Campbell, W. B., Havranek, E. P., Murray, K. T., Olshansky, B., et al. (2004) · Circulation · doi:10.1161/01.cir.0000118472.77237.fa · Cited by 226 · see citing works

Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation

Pluymaekers, N. A. H. A., Dudink, E. A. M. P., LUERMANS, J. G. L. M., Meeder, J. G., Lenderink, T., Widdershoven, J. W. M. G., Bucx, J. J. J., Rienstra, M., Otto Kamp, B., van Opstal, J. M., et al. (2019) · New England Journal of Medicine · doi:10.1056/nejmoa1900353 · Cited by 214 · see citing works

Catheter Ablation Versus Best Medical Therapy in Patients With Persistent Atrial Fibrillation and Congestive Heart Failure

Kück, K., Merkely, B. P., Zahn, R., Arentz, T., Seidl, K., Schlüter, M., Tilz, R. R., Piorkowski, C., Gellér, L., Kleemann, T., et al. (2019) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.119.007731 · Cited by 214 · see citing works

Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients With Heart Failure and Atrial Fibrillation: Results from the RAFT-AF trial

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Sodium‐Glucose Co‐Transporter Inhibitors and Atrial Fibrillation: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

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European Society of Cardiology smartphone and tablet applications for patients with atrial fibrillation and their health care providers

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Atrial fibrillation patients do not benefit from acetylsalicylic acid

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Impact of CPAP on the Atrial Fibrillation Substrate in Obstructive Sleep Apnea

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Anticoagulant Use and Risk of Ischemic Stroke and Bleeding in Patients With Secondary Atrial Fibrillation Associated With Acute Coronary Syndromes, Acute Pulmonary Disease, or Sepsis

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Residual Risk of Stroke and Death in Anticoagulated Patients According to the Type of Atrial Fibrillation: AMADEUS Trial

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Female sex as a risk factor for ischaemic stroke varies with age in patients with atrial fibrillation

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Risk of ischemic stroke and utility of CHA2DS2‐VASc score in women and men with atrial fibrillation

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Durability of pulmonary vein isolation for atrial fibrillation: a meta-analysis and systematic review

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Prevalence of New-Onset Atrial Fibrillation and Associated Outcomes in Patients with Sepsis: A Systematic Review and Meta-Analysis

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Incident Comorbidities, Aging and the Risk of Stroke in 608,108 Patients with Atrial Fibrillation: A Nationwide Analysis

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Thromboembolic events and vascular dementia in patients with atrial fibrillation and low apparent stroke risk

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Great debate: device-detected subclinical atrial fibrillation should be treated like clinical atrial fibrillation

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Performance of DOAC and HAS-BLED scores in predicting major bleeding in Asian patients with non-valvular atrial fibrillation receiving direct oral anticoagulants

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Stroke in Dilated Cardiomyopathy: An Autopsy-Based Study of Mechanisms, Topography, and Clinical Implications

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Catheter Ablation as the First-Line Therapy for Atrial Fibrillation: Update on Evidence and Clinical Implications

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Unusual Evolution of Carotid Atherosclerosis in a Patient with Transient Ischemic Attack

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Does the type of oral anticoagulant matter for stroke prevention or bleeding in patients with atrial fibrillation after cardiac surgery? A systematic review and meta-analysis

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Microbubble and thermal profile of an eight-spline pulsed field ablation system in a pre-clinical model

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Prothrombin complex concentrate for reversal of factor Xa inhibitor-associated acute major gastrointestinal bleeding

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The role of pharmacists in the management of patients with atrial fibrillation: A systematic review and meta-analysis

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Effect of Wall Motion Sampling on CFD ‐Derived Left Atrial Flow Metrics

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Application of Artificial Intelligence in the Early Detection and Management of Atrial Fibrillation: State-of-the-art Review

Mei, D. A., Cherubini, B., Imberti, J. F., Orlandi, M., Vitolo, M., & Boriani, G. (2026) · European Cardiology Review · doi:10.15420/ecr.2025.74 · Cited by 1 · see citing works

Impact of pre-operative factors on post-operative atrial fibrillation outcomes after cardiac surgery: systematic review with meta-analysis, trial sequential analysis, and meta-regression

Khalil, I., Hrebat, M., Abuawwad, T., Zetawi, M., Yassin, B. M., Amayre, S. I., Amarin, H., Gouda, A. G., Khazbak, M. A., Khatib, S., et al. (2026) · Acta cardiologica. Supplementum · doi:10.1080/00015385.2026.2664905 · Cited by 1 · see citing works

Asymptomatic atrial fibrillation in patients treated with BTK inhibitors in hematologic malignancies: a systematic review and metanalysis

Boriani, G., Imberti, J. F., Valenti, A. C., Vitolo, M., López‐Fernández, T., & Mei, D. A. (2026) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2026.106994 · Cited by 1 · see citing works

Fluoroless high-density pulsed field vs radiofrequency ablation for atrial fibrillation guided by left atrial intracardiac echocardiography: The HALO protocol

Saad, G., Slater, C., Fernandes, J. A., dos Santos, G. V., Oliveira, L. A., & Saad, E. (2026) · Heart Rhythm · doi:10.1016/j.hrthm.2026.06.011 · Cited by 1 · see citing works

Autonomic effects and ablation success after pulsed field and cryoballoon ablation: a SINGLE SHOT CHAMPION substudy

Roten, L., Kueffer, T., Badertscher, P., Jüni, P., Knecht, S., Thalmann, G., Kozhuharov, N., Krisai, P., Iqbal, S. U. R., Jufer, C., et al. (2026) · EP Europace · doi:10.1093/europace/euag152 · Cited by 1 · see citing works

From the arrhythmia to the substrate: the role of atrial cardiomyopathy in atrial fibrillation management

Gerra, L., Dall’Ospedale, V., Boriani, G., & Aschieri, D. (2026) · Acta cardiologica. Supplementum · doi:10.1080/00015385.2026.2695396 · Cited by 1 · see citing works

Workup and management of rhythm disorders in myocarditis and inflammatory cardiomyopathy: a clinical consensus statement of the European Heart Rhythm Association and the Heart Failure Association of the ESC, the ESC Working Group on Myocardial & Pericardial Diseases, the European Association of Preventive Cardiology of the ESC, the Heart Rhythm Society, the Asian Pacific Heart Rhythm Society, and the Latin American Heart Rhythm Society

Peretto, G., Basso, C., Berruezo, A., Bollano, E., Caforio, A. L. P., Casella, M., de Chillou, C., Ebert, M., Gati, S., Imazio, M., et al. (2026) · EP Europace · doi:10.1093/europace/euag153 · Cited by 1 · see citing works

Patient preferences for stroke prevention treatments in atrial fibrillation in Asia: A discrete choice experiment

Wang, R., Lu, H., Fernandez, G. S., Krucien, N., Huang, D., Higashiyama, H., Du, J., Ye, X., Tervonen, T., & Quaife, M. (2025) · Preventive Medicine Reports · doi:10.1016/j.pmedr.2025.103084 · Cited by 1 · see citing works

Educating healthcare professionals to improve AF-CARE: lessons from the ESC/EHRA STEEER-AF trial educational programme

van Deutekom, C., Bunting, K. V., Potter, T. J. R. D., Gelder, I. C. V., Kotecha, D., leads, S.-A. E., Robinson, T. G., Potpara, T., Marijon, É., Defaye, P., et al. (2025) · EP Europace · doi:10.1093/europace/euaf142 · Cited by 1 · see citing works

Update der ESC-Vorhofflimmerleitlinien 2024

Schnabel, R. B., Gunawardene, M., Perings, C. A., Steven, D., Busch, H.-J., Deisenhofer, I., Häusler, K. G., Sommer, P., Birkemeyer, R., Eckardt, L., et al. (2025) · Herzschrittmachertherapie + Elektrophysiologie · doi:10.1007/s00399-025-01096-4 · Cited by 1 · see citing works

Stroke prevention in atrial fibrillation patients with end-stage renal disease: how far from Ithaca after a long Odyssey?

Mei, D. A., Tritto, F. P., Imberti, J. F., Vitolo, M., & Boriani, G. (2025) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2025.106455 · Cited by 1 · see citing works

Flecainide and atrial fibrillation cardioversion: what solutions at present and in the near future?

Vitolo, M., Mei, D. A., & Boriani, G. (2025) · EP Europace · doi:10.1093/europace/euaf063 · Cited by 1 · see citing works

From fixed time points to personalized care: rethinking stroke risk management in atrial fibrillation patients

Mei, D. A., Imberti, J. F., & Boriani, G. (2025) · EP Europace · doi:10.1093/europace/euaf215 · Cited by 1 · see citing works

EP Europace: the journey continues, looking ahead to 2025 and beyond

Boriani, G. (2024) · EP Europace · doi:10.1093/europace/euaf006

Atrial fibrillation screening: The importance of the patient perspective

Imberti, J. F., Mei, D. A., & Boriani, G. (2025) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2025.02.028

Optimization of oral anticoagulation in patients with atrial fibrillation: The challenge remains open

Boriani, G., Serafini, K., & Imberti, J. F. (2025) · European Journal of Clinical Investigation · doi:10.1111/eci.70023

Genomic medicine for heart failure prediction in patients with atrial fibrillation

Wijdeveld, L. F. J. M., & Jurgens, S. J. (2025) · EP Europace · doi:10.1093/europace/euaf113

Atrial fibrillation—lost lifetimes and the urgent need for outcome-driven management

Hillmann, H. A. K., Müller‐Leisse, J., & Duncker, D. (2025) · European Heart Journal - Quality of Care and Clinical Outcomes · doi:10.1093/ehjqcco/qcaf042

Venous thromboembolisms and stroke risk in patients with atrial fibrillation: a nationwide cohort study

Jalli, E., Jaakkola, J., Langén, V. L., Airaksinen, J. K. E., Halminen, O., Jukka Putaala, A., Mustonen, P. E., Haukka, J. K., Hartikainen, J. E. K., Linna, M., et al. (2025) · EP Europace · doi:10.1093/europace/euaf155

Physical activity in patients with atrial fibrillation and adverse outcomes: results from a large-scale prospective multicenter European cohort

Vitolo, M., Proietti, M., Mantovani, M., Imberti, J. F., Mei, D. A., Bonini, N., Romiti, G. F., Corica, B., Diemberger, I., Fauchier, L., et al. (2025) · Revista Española de Cardiología (English Edition) · doi:10.1016/j.rec.2025.07.005

Impact of comorbidity patterns on mortality and length of stay in hospitalized patients with atrial fibrillation: a cohort study

Ng, H. S., Woodman, R. J., & Mangoni, A. A. (2025) · Postgraduate Medical Journal · doi:10.1093/postmj/qgaf133

When age meets genetics: refining heart failure risk prediction in young atrial fibrillation

Deng, B., & Liu, W. (2025) · EP Europace · doi:10.1093/europace/euaf201

Impact of renal function on the efficacy of low-voltage area ablation after pulmonary vein isolation: a sub-analysis of the SUPPRESS-AF trial

Matsuda, Y., Masuda, M., Mano, T., Tsujimura, T., Uematsu, H., Ooka, H., Kudo, S., Ochi, M., Okamoto, S., Ishihara, T., et al. (2025) · EP Europace · doi:10.1093/europace/euaf205

Apixaban in subclinical atrial fibrillation: stroke-driven value amid economic uncertainty

Yeh, C.-H., & Chen, S. (2025) · EP Europace · doi:10.1093/europace/euaf262

Repeat ablation for persistent atrial fibrillation: what lies beyond lines and veins?

Boersma, L. V. A., & Yap, S. (2025) · EP Europace · doi:10.1093/europace/euaf269

Possibilities of prevention and treatment of deep vein thrombosis in the lower limbs after arrhythmia-related catheter interventions

Abishev, A. M., Борисович, Ш. Н., Tripoten, M. I., Погорелова, О. А., Yarovoy, S. Y., Mironov, N. Y., Новиков, П. С., & Balakhonova, T. V. (2025) · Eurasian heart journal · doi:10.38109/2225-1685-2025-4-82-87

The role of sarcopenia in determining the risk of adverse events in atrial fibrillation: advancing the need for a geriatric approach

Proietti, M., Ronca, A., & Boriani, G. (2025) · EP Europace · doi:10.1093/europace/euaf310

Alcohol use disorder and use of rhythm control therapies in patients with atrial fibrillation: A nationwide cohort study

Vanhanen, M., Jaakkola, J., Airaksinen, J. K. E., Halminen, O., Jukka Putaala, A., Mustonen, P. E., Haukka, J. K., Hartikainen, J. E. K., Luojus, A., Niemi, M., et al. (2025) · IJC Heart & Vasculature · doi:10.1016/j.ijcha.2025.101854

Intensification of monitoring for improving detection of atrial fibrillation after a presumed “trigger- induced episode” due to potentially reversible factors: what tools and what implications for decision making?

Boriani, G., Cherubini, B., & Mei, D. A. (2025) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2025.106660

Evolution in the approach to atrial fibrillation: from screening for asymptomatic episodes to implementing artificial intelligence for refined risk prediction

Boriani, G., & Mei, D. A. (2025) · Journal of Cardiovascular Medicine · doi:10.2459/jcm.0000000000001814

Relationship between atrial fibrillation ablation and gross domestic product across Europe

Xhakupi, H., Ameri, P., & Porto, I. (2026) · EP Europace · doi:10.1093/europace/euaf309

Early differentiation between paroxysmal and persistent atrial fibrillation based on interpretable machine learning: a multicenter retrospective study

Li, S., Zhang, Y., Wu, W., Li, G., Huang, T., Zeng, K., Tong, C., Li, H., & Huang, H. (2026) · BioData Mining · doi:10.1186/s13040-026-00525-5

Alcohol consumption and incident atrial fibrillation: rethinking dose, risk, and dogma

Zuin, M., Bertini, M., & Boriani, G. (2026) · EP Europace · doi:10.1093/europace/euag029

eHealth tools in atrial fibrillation management: An ecological cross-sectional analysis and bibliometric review of research trends and knowledge gaps

Zhou, X., Zhang, S., Hu, L. I. N., Liao, L., Xie, Z., & Li, X. (2026) · Digital Health · doi:10.1177/20552076261427101

Gut microbiota dysbiosis promotes chronic kidney disease-associated atrial fibrillation through activation of the NLRP3 inflammasome

Han, X., Yu, H., Gao, Q., Wang, X., Zhang, L., Zhao, Q., Yu, L., Zhang, Y., Sui, M., & Li, Y. (2026) · EP Europace · doi:10.1093/europace/euag037

Atrial fibrillation after cavotricuspid isthmus ablation for isolated typical atrial flutter: contemporary insights from a large global federated research network

Fauchier, L., Lemrini, Y., Lenormand, T., & Bisson, A. (2026) · EP Europace · doi:10.1093/europace/euag085

Empowering atrial fibrillation detection with TabPFN and SHAP interpretation based on ECG-derived features: a dual-center temporal validation study

Chen, M., Li, T., Wang, Z., Fan, X., Xu, H., Zhou, Y.-N., & Hu, M. (2026) · BMC Cardiovascular Disorders · doi:10.1186/s12872-026-05936-0

Factors influencing kinesiophobia after radiofrequency catheter ablation in patients with atrial fibrillation: a cross-sectional study

Zheng, Y., Xu, R., Mengying, Y., Zhang, H., Zuo, T., & Yu, P. (2026) · Frontiers in Public Health · doi:10.3389/fpubh.2026.1807261

Safety and effectiveness of the TactiFlex duo system: 6-month results of the FOCALFLEX study

Manninger, M., Scherr, D., Bulava, A., Kalman, J. M., Sanders, P., Bella, P. E. D., Martinek, M., Deisenhofer, I., Wijnmaalen, A. P., Osca, J., et al. (2026) · EP Europace · doi:10.1093/europace/euag108

Comprehensive assessment of novel cardiovascular biomarkers in AF

Ohlrogge, A. H., Engler, D., Schlieker, P., Seum, F., Rosebrock, K., Nebel, N., Csengeri, D., Fabritz, L., Ziegler, A., Blankenberg, S., et al. (2026) · EP Europace · doi:10.1093/europace/euag096

More than an OPTION: left atrial appendage closure beyond high bleeding risk in the post-ablation setting

Schiavone, M., & Biase, L. D. (2026) · EP Europace · doi:10.1093/europace/euag119

Percutaneous left atrial appendage closure following catheter ablation therapy of atrial fibrillation: outcomes stratified by bleeding risk – a sub-analysis of the OPTION study

Phillips, K. P., Nair, D. G., Boersma, L. V. A., Doshi, R. N., Healey, J. S., Jaber, W. A., MANSOUR, M. C., Reddy, V. Y., Tondo, C., Natale, A., et al. (2026) · EP Europace · doi:10.1093/europace/euag093

The 2024 ESC guidelines on atrial fibrillation: essential updates for everyday clinical practice

Boriani, G., Mei, D. A., Vitolo, M., & Imberti, J. F. (2025) · Internal and Emergency Medicine · doi:10.1007/s11739-025-04006-1 · Cited by 22 · see citing works

Analysis of The 2024 ESC/EACTS Guidelines For The Management Of Atrial Fibrillation

Ripoll, J. G., Chang, M. G., Bittner, E. A., Ortoleva, J. P., Khromava, M., Bradley, D. T., Griffin, E. K., Soto, J. C. D., Wieruszewski, P. M., Chang, K., et al. (2024) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2024.11.020 · Cited by 5 · see citing works

AF-CARE: The current approach in atrial fibrillation management

Rizal, A. (2025) · Heart Science Journal · doi:10.21776/ub.hsj.2025.006.02.1

The 2024 European Society of Cardiology Atrial Fibrillation Guidelines: A Moving Goalpost

Dan, G., & Martínez‐Rubio, A. (2025) · European Cardiology Review · doi:10.15420/ecr.2024.55 · Cited by 2 · see citing works

A Holistic Approach to Improving Outcomes in Atrial Fibrillation: The AF-CARE Pathway

Griffin, M., & Mills, M. T. (2025) · British Journal of Hospital Medicine · doi:10.12968/hmed.2024.0929 · Cited by 1 · see citing works