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E-Cigarettes: A Scientific Review
Open accessAbstract
chemicals delivered to users and the air pollution generated by the exhaled aerosol. 19-liquids are flavored, including tobacco, menthol, coffee, fruit, candy, and alcohol flavors, as well as unusual flavors such as cola and Belgian waffle. 3Flavored (conventional) tobacco products are used disproportionately by youth and initiators
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“However, lack of federal regulations and a wide selection of flavors make e-cigarettes not only accessible, but also appealing to young people (Grana et al. 2014).”
From Nicotine and the adolescent brain (2015) · cites this paper as Grana et al. 2014
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“In spite of the prevalence of this proposition on e-cigarette retail websites, Grana et al. (2014) note that empirical evidence supporting this view is limited.”
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“Nicotine is also the principal pharmacologically active component in a range of heat-not-burn tobacco products, pharmaceutical nicotine replacement therapy products [7] and electronic cigarette devices [8].”
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Ford, E. W., Chan, K. S., Parikh, M. A., Lowe, K. B., & Huerta, T. R. (2020) · Addictive Behaviors Reports · doi:10.1016/j.abrep.2019.100246 · Cited by 7
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Are e-cigarettes beneficial for public health: Hume's guillotine – The debate continues?
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Wu, S., Kim, E., & Zhao, R. (2023) · Environmental Science & Technology · doi:10.1021/acs.est.3c08514 · Cited by 6
An overview of traditional smoking cessation interventions and E-cigarettes
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Kappa-opioid receptor activation reinstates nicotine self-administration in mice
Gowrishankar, R., Gomez, A. M., Walicki, M. C., & Bruchas, M. R. (2022) · Addiction Neuroscience · doi:10.1016/j.addicn.2022.100017 · Cited by 6
Tobacco Smoke Exposure and Lactation
Vlachou, M., Kyrkou, G. A., Vivilaki, V. G., GEORGAKOPOULOU, V. E., Katsaounou, P. A., Κapetanaki, A., & Diamanti, A. (2024) · Cureus · doi:10.7759/cureus.73651 · Cited by 9
Constituents of smoke from cigarettes made from diverted nicotine replacement therapy patches
Morrissey, H., Ball, P., Boland, M. P., Hefler, M., & Thomas, D. (2015) · Drug and Alcohol Review · doi:10.1111/dar.12288 · Cited by 6
E-Cigarettes: Policy Options and Legal Issues Amidst Uncertainty
Kaufman, N. J., & Mahoney, M. R. (2015) · The Journal of Law Medicine & Ethics · doi:10.1111/jlme.12209 · Cited by 6
Whitsel, L. P., Benowitz, N. L., Bhatnagar, A., Bullen, C., Goldstein, F., Matthias-Gray, L., Grossmeier, J. J., Harris, J., Isaac, F. W., Loeppke, R., et al. (2015) · Journal of Occupational and Environmental Medicine · doi:10.1097/jom.0000000000000420 · Cited by 6
Self-citationSnus and Snuff Use in Switzerland Among Young Men: Are There Beneficial Effects on Smoking?
Gmel, G. E., Clair, C., Rougemont-Bücking, A., Grazioli, V. S., Daeppen, J., Mohler‐Kuo, M., & Studer, J. (2017) · Nicotine & Tobacco Research · doi:10.1093/ntr/ntx224 · Cited by 6
Biological Toxicity of the Compositions in Electronic-Cigarette on Cardiovascular System
Lai, L., & Qiu, H. (2020) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-020-10060-1 · Cited by 10
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Alternative Tobacco Product Use in Critically Ill Patients
Liu, T., Deiss, T. J., Lippi, M., Jauregui, A., Vessel, K., Ke, S., Belzer, A., Zhuo, H., Kangelaris, K. N., Gomez, A. D., et al. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17238707 · Cited by 6
“For example, self-responders were younger, more likely to be male, and were more likely to be current cigarette smokers, factors that have been associated with a greater likelihood of ATP usage in other cohorts [4,17,20,43].”
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“…tobacco smoke (Floyd et al. 2018; Margham et al. 2016; Sahu et al. 2013; Cheng 2014; Trtchounian, Williams, and Talbot 2010; Fernandez et al. 2015; Grana, Benowitz, and Glantz 2014) that require special attention when vaping exposure systems are designed. e-cig aerosol exhibits larger particle…”
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Hu, S.-C., Min, S., Kang, H.-K., Yang, D.-J., Basavarajappa, M. S., Lewis, S. M., Davis, K. J., Patton, R. E., Bryant, M., Sepehr, E., et al. (2021) · Food and Chemical Toxicology · doi:10.1016/j.fct.2021.112780 · Cited by 6
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“These products vaporize a liquid substance containing nicotine, flavoring agents, propylene glycol, and/or glycerol (Grana, Benowitz, and Glantz 2014).”
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“(16) 일반 담배와 함께 사용할 경우 위험 물질의 노출 은 일반 담배 단독 흡연보다 훨씬 높다.(17-19) 전자 담배의 간 접 노출 역시 건강에 해를 줄 가능성이 있다.”
Martinez, L. S., Tsou, M., & Spitzberg, B. H. (2019) · International Conference on Social Media and Society (SMSociety) · doi:10.1145/3328529.3328540 · Cited by 6
“E-cigarette use is a growing public health concern because these devices may contain potentially toxic chemicals [25] and their long-term effects on health remain unestablished [26].”
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Jiang, T. H., Cheng, L. M., & Hawkins, M. A. (2017) · The International Journal of Health Planning and Management · doi:10.1002/hpm.2440 · Cited by 6
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E-cigarettes and vaping, new spotlight on smoking as an old cardiovascular risk factor?
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Heating Up the Debate: E-cigarettes and Instagram
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Electronic Nicotine Delivery Systems (ENDS): What Nurses Need to Know
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“…is available Grana, Benowitz, and Glantz (2013) ENDS delivers quantitatively less toxins than conventional cigarettes, yet delivers toxins Grana, Benowitz, and Glantz (2014) Provides continued discussion of market demographics and trends across countries; discusses possible future…”
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“Poorly manufactured e-cigarettes and e-liquids can generate even more harmful constituents than traditional cigarettes [1].”
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World no-tobacco: effects of second-hand smoke (SHS) and vapors on the developing and adult brain
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“Other harmful metals and compounds such as lead, tin, nickel, chromium arsenic, nitrosamine, have also been found in the vapors.(36,37) Exposure to nicotine through ENDS can cause harm or symptoms that lead to uncontrolled asthma.”
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Association between e-cigarette and conventional cigarette use among Spanish adolescents
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Deconstructing ENDS aerosols: generation and characterization methods
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Cardiologists and Electronic Cigarettes
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Metadata
- Authors
- Grana, R., Benowitz, N., & Glantz, S. A.
- Affiliations
- University of California, San Francisco (US)
- Corresponding author
- Glantz, Stanton A.
- Venue
- Circulation
- Published
- 2014-05-13
- Volume
- 129
- Issue
- 19
- Pages
- 1972-1986
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- PMC
- PMC4018182
- OpenAlex
- W2164470169
- Cited by
- 1,194
- References
- 112
- Citations by year
- 2026: 49 · 2025: 51 · 2024: 52 · 2023: 57 · 2022: 67 · 2021: 85 · 2020: 110 · 2019: 97 · 2018: 116 · 2017: 130 · 2016: 170 · 2015: 151 · 2014: 58
- FWCI
- 113.12
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Circulation (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Funders
- World Health Organization
- National Cancer Institute (P50CA180890)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Global Public Health Policies and Epidemiology
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Inhalation and Respiratory Drug Delivery
- Keywords
- electronic cigarettes, flavored tobacco products, tobacco aroma, youth tobacco use, tobacco product regulation, exhaled aerosols, air pollution
- MeSH terms
- Electronics, Humans, Risk Factors, Smoking, Smoking Cessation, Treatment Outcome, Tobacco Products
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