The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.
Aging, Arterial Stiffness, and Hypertension
Open accessAbstract
Although the etiology of essential hypertension remains unknown, it is clear that multiple factors may contribute to the pathogenesis of hypertension. Hypertension is an outcome of the interaction of multiple genetic and environmental factors. Several epidemiological studies indicated that the incidence of arterial stiffness and hypertension and related cardiovascular disease (stroke, myocardial infarction) is higher in the aged than in the young population.1–4 The prevalence of arterial stiffening and hypertension increases with age.1,5 Based on an epidemiological study,6 the prevalence of hypertension is more than doubled in the elderly than in the young population. More than two-thirds of individuals after 65 years of age experience hypertension according to the Seventh Report of the Joint National Committee (JNC-7).7 Therefore, it is generally thought that hypertension is an aging disorder. In recent years, metabolic syndrome and hypertension are increasingly seen in the middle-aged and young populations. In these subpopulations, insulin resistance and overproduction of adipokines impair endothelial and heart function leading to early and accelerated cardiovascular aging. It was reported that premature aging (progeria) is associated with accelerated vascular stiffening or vascular aging.8 Aging is defined as the age-related decline in physiological function essential for survival and fertility. Cardiovascular aging is an important factor that determines life span. The wall of large conduit arteries, especially aorta, thicken and lose elasticity over time, and this process results in an increase in pulse wave velocity, an important and reliable measure of arterial stiffness. The increased arterial stiffness, whatever its underlying causes, would reduce the reservoir/buffering function of the conduit arteries near the heart and increase pulse wave velocity, both of which increase systolic and pulse pressure. Therefore, aging-related hypertension is characterized by a significant increase in systolic blood pressure with no change or even a …
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Chobanian, A. V. (2003) · JAMA · doi:10.1001/jama.289.19.2560 · Cited by 25,386
Chobanian, A. V., Bakris, G. L., Black, H. R., Cushman, W. C., Green, L. A., Izzo, J. L., Jones, D. W., Materson, B. J., Oparil, S., Wright, J. T., et al. (2003) · Hypertension · doi:10.1161/01.hyp.0000107251.49515.c2 · Cited by 13,271
Prevalence, Awareness, Treatment, and Control of Hypertension Among United States Adults 1999–2004
Ong, K. L., Cheung, B. M. Y., Man, Y. B., Lau, C. P., & Lam, K. S. L. (2007) · Hypertension · doi:10.1161/01.hyp.0000252676.46043.18 · Cited by 1,395
Aortic Stiffness, Blood Pressure Progression, and Incident Hypertension
Kaess, B. M., Rong, J., Larson, M. G., Hamburg, N. M., Vita, J. A., Levy, D., Benjamin, E. J., Vasan, R. S., & Mitchell, G. F. (2012) · JAMA · doi:10.1001/2012.jama.10503 · Cited by 1,086
AlGhatrif, M., Strait, J. B., Morrell, C. H., Canepa, M., Wright, J., Elango, P., Scuteri, A., Najjar, S. S., Ferrucci, L., & Lakatta, E. G. (2013) · Hypertension · doi:10.1161/hypertensionaha.113.01445 · Cited by 409
Sodium and volume sensitivity of blood pressure. Age and pressure change over time.
Weinberger, M. H., & Fineberg, N. S. (1991) · Hypertension · doi:10.1161/01.hyp.18.1.67 · Cited by 382
Current understanding of klotho
Wang, Y., & Sun, Z. (2009) · Ageing Research Reviews · doi:10.1016/j.arr.2008.10.002 · Cited by 327
Self-citationArterial Stiffening Precedes Systolic Hypertension in Diet-Induced Obesity
Weisbrod, R. M., Shiang, T., Al Sayah, L., Fry, J. L., Bajpai, S., Reinhart-King, C. A., Lob, H. E., Santhanam, L., Mitchell, G., Cohen, R. A., et al. (2013) · Hypertension · doi:10.1161/hypertensionaha.113.01744 · Cited by 317
Hashimoto, J., & Ito, S. (2011) · Hypertension · doi:10.1161/hypertensionaha.111.177469 · Cited by 259
Wu, J., Thabet, S. R., Kirabo, A., Trott, D. W., Saleh, M. A., Xiao, L., Madhur, M. S., Chen, W., & Harrison, D. G. (2014) · Circulation Research · doi:10.1161/circresaha.114.302157 · Cited by 242
Cited by
Buford, T. W. (2016) · Ageing Research Reviews · doi:10.1016/j.arr.2016.01.007 · Cited by 561
McCullough, D., Webb, R., Enright, K. J., Lane, K. E., McVeigh, J., Stewart, C. E., & Davies, I. G. (2021) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-020-09616-y · Cited by 62
Reichert, T., Costa, R. R., Barroso, B. M., da Rocha, V. D. M. B., Delevatti, R. S., & Kruel, L. F. M. (2018) · Sports Medicine · doi:10.1007/s40279-018-0918-0 · Cited by 34
Hays, C. C., Zlatar, Z. Z., Campbell, L., Meloy, M. J., & Wierenga, C. E. (2018) · Journal of the International Neuropsychological Society · doi:10.1017/s135561771700087x · Cited by 34
Boubouchairopoulou, N., Ntineri, A., Kollias, A., Destounis, A., & Stergiou, G. S. (2021) · Hypertension Research · doi:10.1038/s41440-021-00736-9 · Cited by 25
Metadata
- Authors
- Sun, Z.
- Venue
- Hypertension
- Published
- 2015-02
- Volume
- 65
- Issue
- 2
- Pages
- 252-256
- ISSN
- 0194-911X (ISSN-L)
- 1524-4563
- OpenAlex
- W2162006322
- Cited by
- 594
- References
- 48
- FWCI
- 18.32
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Aging, Arterial Stiffness, and Hypertension. https://app.cochat.ai/papers/10.1161/hypertensionaha.114.03617
- The paper
- Sun, Z. (2015). Aging, Arterial Stiffness, and Hypertension. Hypertension. https://doi.org/10.1161/hypertensionaha.114.03617
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
