The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Cardiovascular and Cerebrovascular Emergency Department Visits Associated With Wildfire Smoke Exposure in California in 2015
Open accessAbstract
Background: Wildfire smoke is known to exacerbate respiratory conditions; however, evidence for cardiovascular and cerebrovascular events has been inconsistent, despite biological plausibility. Methods and Results: A population‐based epidemiologic analysis was conducted for daily cardiovascular and cerebrovascular emergency department ( ED ) visits and wildfire smoke exposure in 2015 among adults in 8 California air basins. A quasi‐Poisson regression model was used for zip code‐level counts of ED visits, adjusting for heat index, day of week, seasonality, and population. Satellite‐imaged smoke plumes were classified as light, medium, or dense based on model‐estimated concentrations of fine particulate matter. Relative risk was determined for smoky days for lag days 0 to 4. Rates of ED visits by age‐ and sex‐stratified groups were also examined. Rates of all‐cause cardiovascular ED visits were elevated across all lags, with the greatest increase on dense smoke days and among those aged ≥65 years at lag 0 (relative risk 1.15, 95% confidence interval [1.09, 1.22]). All‐cause cerebrovascular visits were associated with smoke, especially among those 65 years and older, (1.22 [1.00, 1.49], dense smoke, lag 1). Respiratory conditions were also increased, as anticipated (1.18 [1.08, 1.28], adults >65 years, dense smoke, lag 1). No association was found for the control condition, acute appendicitis. Elevated risks for individual diagnoses included myocardial infarction, ischemic heart disease, heart failure, dysrhythmia, pulmonary embolism, ischemic stroke, and transient ischemic attack. Conclusions: Analysis of an extensive wildfire season found smoke exposure to be associated with cardiovascular and cerebrovascular ED visits for all adults, particularly for those over aged 65 years.
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“These 3 pathways can lead to an increase in systemic oxidative stress, endothelial dysfunction, and other inflammatory responses, in addition to platelet activation, hypercoagulability, and vasoconstriction.(18,29,30) Acute PM2.”
BackgroundLong-term ozone exposure and mortality
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A systematic review of the physical health impacts from non-occupational exposure to wildfire smoke
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Air Pollution Exposure and Blood Pressure: An Updated Review of the Literature
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Extreme Weather and Climate Change: Population Health and Health System Implications
Ebi, K. L., Vanos, J., Baldwin, J. W., Bell, J. E., Hondula, D. M., Errett, N. A., Hayes, K., Reid, C. E., Saha, S., Spector, J., et al. (2021) · Annual Review of Public Health · doi:10.1146/annurev-publhealth-012420-105026 · Cited by 1,213
Environmental determinants of cardiovascular disease: lessons learned from air pollution
Al-Kindi, S. G., Brook, R. D., Biswal, S., & Rajagopalan, S. (2020) · Nature Reviews Cardiology · doi:10.1038/s41569-020-0371-2 · Cited by 782
Contribution of Wildland-Fire Smoke to US PM2.5 and Its Influence on Recent Trends
O’Dell, K., Ford, B., Fischer, E. V., & Pierce, J. R. (2019) · Environmental Science & Technology · doi:10.1021/acs.est.8b05430 · Cited by 285
Wildfire smoke exposure under climate change: impact on respiratory health of affected communities
Reid, C. E., & Maestas, M. M. (2019) · Current Opinion in Pulmonary Medicine · doi:10.1097/mcp.0000000000000552 · Cited by 169
Hutchinson, J. A., Vargo, J., Milet, M., French, N. H. F., Billmire, M., Johnson, J., & Hoshiko, S. (2018) · PLOS Medicine · doi:10.1371/journal.pmed.1002601 · Cited by 167
Self-citation
Metadata
- Authors
- Wettstein, Z. S., Hoshiko, S., Fahimi, J., Harrison, R. J., Cascio, W. E., & Rappold, A. G.
- Venue
- Journal of the American Heart Association
- Published
- 2018-04-17
- Volume
- 7
- Issue
- 8
- ISSN
- 2047-9980 (ISSN-L)
- OpenAlex
- W2797340806
- Cited by
- 249
- References
- 9
- FWCI
- 10.44
- Type
- journal article
- Language
- en
- Open access
- gold
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- Wettstein, Z. S., Hoshiko, S., Fahimi, J., Harrison, R. J., Cascio, W. E., & Rappold, A. G. (2018). Cardiovascular and Cerebrovascular Emergency Department Visits Associated With Wildfire Smoke Exposure in California in 2015. Journal of the American Heart Association. https://doi.org/10.1161/jaha.117.007492
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