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Evidence of Developmental Differences in Implicit Sequence Learning: An fMRI Study of Children and Adults
Abstract
Prevailing theories of implicit or unaware learning propose a developmental invariance model, with implicit function maturing early in infancy or childhood despite prolonged improvements in explicit or intentional learning and memory systems across childhood. Neuroimaging studies of adult visuomotor sequence learning have associated fronto-striatal brain regions with implicit learning of spatial sequences. Given evidence of continued development in these brain regions during childhood, we compare implicit sequence learning in adults and 7- to 11-year-old children to examine potential developmental differences in the recruitment of fronto-striatal circuitry during implicit learning. Participants performed a standard serial reaction time task. Stimuli alternately followed a fixed 10-step sequence of locations or were presented in a pseudorandom order of locations. Adults outperformed children, achieving a significantly larger sequence learning effect and showing learning more quickly than children. Age-related differences in activity were observed in the premotor cortex, putamen, hippocampus, inferotemporal cortex, and parietal cortex. We observed differential recruitment of cortical and subcortical motor systems between groups, presumably reflecting age differences in motor response execution. Adults showed greater hippocampal activity for sequence trials, whereas children demonstrated greater signal during random trials. Activity in the right caudate correlated significantly…
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“Differential recruitment of prefrontal and subcortical regions has been reported across a number of developmental fMRI studies (Casey et al. 2002; Monk et al. 2003; Thomas et al. 2004).”
From The Adolescent Brain (2008) · cites this paper as Thomas et al. 2004
In the citing paper
“In children, skill performance is generally much slower, less accurate, and less automated than in adults, particularly in the initial stage of training (318, 385, 1185), which gives rise to the question of whether sleep enhances skill memories also in children if presleep performance is improved to a level comparable with that in adults.”
From About Sleep's Role in Memory (2013) · cites this paper as [1185]
Citations
Cites
Co-Planar Stereotaxic Atlas of the Human Brain
Talairach, J., & Tournoux, P. (1988) · Medical Entomology and Zoology · Cited by 11,798
AFNI: Software for analysis and visualization of functional magnetic resonance neuroimages
Cox, R. W. (1996) · Computers and Biomedical Research · doi:10.1006/cbmr.1996.0014 · Cited by 10,913
Statistical learning by 8-month-old infants
Saffran, J. R., Aslin, R. N., & Newport, E. L. (1996) · Science · doi:10.1126/science.274.5294.1926 · Cited by 5,659
Brain development during childhood and adolescence: a longitudinal MRI study
Giedd, J. N., Blumenthal, J., Jeffries, N. O., Castellanos, F. X., Liu, H., Zijdenbos, A., Paus, T., Evans, A. C., & Rapoport, J. L. (1999) · Nature Neuroscience · doi:10.1038/13158 · Cited by 5,552
Attentional requirements of learning: Evidence from performance measures
Nissen, M. J., & Bullemer, P. (1987) · Cognitive Psychology · doi:10.1016/0010-0285(87)90002-8 · Cited by 2,966
Cohen, N. J., & Squire, L. R. (1980) · Science · doi:10.1126/science.7414331 · Cited by 2,296
Rapid Automated Algorithm for Aligning and Reslicing PET Images
Woods, R. P., Cherry, S. R., & Mazziotta, J. C. (1992) · Journal of Computer Assisted Tomography · doi:10.1097/00004728-199207000-00024 · Cited by 1,901
Functional MRI evidence for adult motor cortex plasticity during motor skill learning
Kami, A., Meyer, G., Jezzard, P., Adams, M. M., Turner, R., & Ungerleider, L. G. (1995) · Nature · doi:10.1038/377155a0 · Cited by 1,883
Practice-related Changes in Human Brain Functional Anatomy during Nonmotor Learning
Raichle, M. E., Fiez, J. A., Videen, T. O., MacLeod, A.-M. K., Pardo, J. V., Fox, P. T., & Petersen, S. E. (1994) · Cerebral Cortex · doi:10.1093/cercor/4.1.8 · Cited by 1,593
In vivo evidence for post-adolescent brain maturation in frontal and striatal regions
Sowell, E. R., Thompson, P. M., Holmes, C. J., Jernigan, T. L., & Toga, A. W. (1999) · Nature Neuroscience · doi:10.1038/13154 · Cited by 1,439
Implicit learning and tacit knowledge: an essay on the cognitive unconscious
(1994) · Choice Reviews Online · doi:10.5860/choice.31-3490 · Cited by 1,432
Quantitative magnetic resonance imaging of human brain development: ages 4–18
Giedd, J. N., Snell, J. W., Lange, N., Rajapakse, J. C., Casey, B. J., Kozuch, P. L., Vaituzis, A. C., Vauss, Y. C., Hamburger, S. D., Kaysen, D., et al. (1996) · Cerebral Cortex · doi:10.1093/cercor/6.4.551 · Cited by 1,024
Distinct contribution of the cortico-striatal and cortico-cerebellar systems to motor skill learning
Doyon, J., Penhune, V. B., & Ungerleider, L. G. (2002) · Neuropsychologia · doi:10.1016/s0028-3932(02)00158-6 · Cited by 885
COGNITIVE NEUROSCIENCE OF HUMAN MEMORY
Gabrieli, J. D. E. (1998) · Annual Review of Psychology · doi:10.1146/annurev.psych.49.1.87 · Cited by 808
Maturation of widely distributed brain function subserves cognitive development.
Luna, B., Thulborn, K. R., Munoz, D. P., Merriam, E. P., Garver, K. E., Minshew, N. J., Keshavan, M. S., Genovese, C. R., Eddy, W. F., & Sweeney, J. A. (2001) · NeuroImage · doi:10.1006/nimg.2000.0743 · Cited by 757
Functional mapping of sequence learning in normal humans
Grafton, S. T., Hazeltine, E., & Ivry, R. (1995) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.1995.7.4.497 · Cited by 720
Imaging brain plasticity during motor skill learning
Ungerleider, L. (2002) · Neurobiology of Learning and Memory · doi:10.1006/nlme.2002.4091 · Cited by 641
Buckner, R. L., Goodman, J. M., Burock, M. A., Rotte, M., Koutstaal, W., Schacter, D. L., Rosen, B. R., & Dale, A. M. (1998) · Neuron · doi:10.1016/s0896-6273(00)80456-0 · Cited by 624
An fMRI Study of the Role of the Medial Temporal Lobe in Implicit and Explicit Sequence Learning
Schendan, H. E., Searl, M. M., Melrose, R. J., & Stern, C. E. (2003) · Neuron · doi:10.1016/s0896-6273(03)00123-5 · Cited by 610
Attentional and nonattentional forms of sequence learning.
Curran, T., & Keele, S. W. (1993) · Journal of Experimental Psychology: Learning, Memory, and Cognition · doi:10.1037/0278-7393.19.1.189 · Cited by 594 · cited 2×
“Adult behavioral paradigms have indicated that completely ambiguous sequences are more difficult to learn (Reed, 1994; Curran & Keele, 1993).”
BackgroundHeindel, W. C., Salmon, D., Shults, C., Walicke, P. A., & Butters, N. (1989) · Journal of Neuroscience · doi:10.1523/jneurosci.09-02-00582.1989 · Cited by 582
The effects of practice on the functional anatomy of task performance
Petersen, S. E., Mier, H. I. V., Fiez, J. A., & Raichle, M. E. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.3.853 · Cited by 530
Changes in cerebral functional organization during cognitive development
Casey, B. J., Galván, A., & Hare, T. A. (2005) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2005.03.012 · Cited by 506
Stadler, M. A., & Frensch, P. A. (1998) · Medical Entomology and Zoology · Cited by 483
Procedural learning in Parkinson's disease and cerebellar degeneration
Pascual‐Leone, Á., Grafman, J. H., Clark, K., Stewart, M., Massaquoi, S. G., Lou, J., & Hallett, M. (1993) · Annals of Neurology · doi:10.1002/ana.410340414 · Cited by 481
Reed, J., & Johnson, P. J. (1994) · Journal of Experimental Psychology Learning Memory and Cognition · doi:10.1037/0278-7393.20.3.585 · Cited by 431
Memory development between 2 and 20
(1989) · Choice Reviews Online · doi:10.5860/choice.27-1218 · Cited by 391
Brain Regions Responsive to Novelty in the Absence of Awareness
Berns, G. S., Cohen, J. D., & Mintun, M. A. (1997) · Science · doi:10.1126/science.276.5316.1272 · Cited by 367
Buckner, R. L. (2000) · Brain · doi:10.1093/brain/123.3.620 · Cited by 345
Patterns of regional brain activation associated with different forms of motor learning
Ghilardi, M. F., Ghez, C. P., DHAWAN, V. M., Moeller, J. R., Mentis, M. J., Nakamura, T., Antonini, A., & Eidelberg, D. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02365-9 · Cited by 339
Abstract and Effector-Specific Representations of Motor Sequences Identified with PET
Grafton, S. T., Hazeltine, E., & Ivry, R. B. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-22-09420.1998 · Cited by 333
Direct Comparison of Neural Systems Mediating Conscious and Unconscious Skill Learning
Willingham, D. B., Salidis, J., & Gabrieli, J. D. E. (2002) · Journal of Neurophysiology · doi:10.1152/jn.2002.88.3.1451 · Cited by 327
Conscious knowledge and changes in performance in sequence learning: Evidence against dissociation.
Perruchet, P., & Amorim, M. (1992) · Journal of Experimental Psychology Learning Memory and Cognition · doi:10.1037//0278-7393.18.4.785 · Cited by 320
Clinical, imaging, lesion, and genetic approaches toward a model of cognitive control
Casey, B. J., Tottenham, N., & Fossella, J. (2002) · Developmental Psychobiology · doi:10.1002/dev.10030 · Cited by 269
Mostofsky, S. H., Goldberg, M. C., Landa, R. J., & DENCKLA, M. B. (2000) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617700677020 · Cited by 252
Serial reaction time learning and Parkinson's disease: Evidence for a procedural learning deficit
Jackson, G. M., Jackson, S. R., Harrison, J., Henderson, L., & Christopher Kennard, C. (1995) · Neuropsychologia · doi:10.1016/0028-3932(95)00010-z · Cited by 249
A PET investigation of implicit and explicit sequence learning
Rauch, S. L., Savage, C. R., Brown, H. D., Curran, T., Alpert, N. M., Kendrick, A., Fischman, A. J., & Kosslyn, S. M. (1995) · Human Brain Mapping · doi:10.1002/hbm.460030403 · Cited by 241
Implicit Sequence Learning in Children
Meulemans, T., der Linden, M. V., & Perruchet, P. (1998) · Journal of Experimental Child Psychology · doi:10.1006/jecp.1998.2442 · Cited by 231
Procedural memory in Parkinson's disease: Impaired motor but not visuoperceptual learning
Harrington, D. L., Haaland, K. Y., Yeo, R. A., & Marder, E. (1990) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/01688639008400978 · Cited by 221
Implicit learning deficit in children with developmental dyslexia
Vicari, S., Marotta, L., Menghini, D., Molinari, M., & Petrosini, L. (2002) · Neuropsychologia · doi:10.1016/s0028-3932(02)00082-9 · Cited by 200
Gabrieli, J. D. E., Stebbins, G. T., Singh, J., Willingham, D. B., & al, E. (1997) · Neuropsychology · doi:10.1037/0894-4105.11.2.272 · Cited by 188
Canfield, R. L., Smith, E. G., Brezsnyak, M. P., Snow, K. L., Aslin, R. Ν., Haith, M. M., Wass, T. S., & Adler, S. A. (1997) · Monographs of the Society for Research in Child Development · doi:10.2307/1166196 · Cited by 180
Similar network activated by young and old adults during the acquisition of a motor sequence
Daselaar, S. M., Rombouts, S. A. R. B., Veltman, D. J., Raaijmakers, J. G. W., & Jonker, C. (2003) · Neurobiology of Aging · doi:10.1016/s0197-4580(03)00030-7 · Cited by 179
Serial Reaction Time Learning in Preschool- and School-Age Children
Thomas, K. M., & Nelson, C. A. (2001) · Journal of Experimental Child Psychology · doi:10.1006/jecp.2000.2613 · Cited by 163
Self-citationDissociating Explicit and Implicit Category Knowledge with fMRI
Reber, P. J., Gitelman, D. R., Parrish, T. B., & Mesulam, M. M. (2003) · Journal of Cognitive Neuroscience · doi:10.1162/089892903321662958 · Cited by 161
Casey, B. J., Thomas, K. M., Davidson, M. C., Kunz, K., & Franzen, P. L. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-19-08647.2002 · Cited by 137
Self-citationVakil, E., Kahan, S., Huberman, M., & Osimani, A. (2000) · Neuropsychologia · doi:10.1016/s0028-3932(99)00058-5 · Cited by 131
Evidence for implicit sequence learning in dyslexia
Kelly, S. W., Griffiths, S., & Uta Frith, A. (2002) · Dyslexia · doi:10.1002/dys.208 · Cited by 129
Functional MRI of motor sequence acquisition: effects of learning stage and performance
Müller, R.-A., Kleinhans, N. M., Pierce, K., Kemmotsu, N., & Courchesne, E. (2002) · Cognitive Brain Research · doi:10.1016/s0926-6410(02)00131-3 · Cited by 123
Implicit and explicit memory in young children and adults
Parkin, A. J., & Streete, S. (1988) · British Journal of Psychology · doi:10.1111/j.2044-8295.1988.tb02295.x · Cited by 122
Stability of visual expectations at 3.0 months of age.
Haith, M. M., & McCarty, M. E. (1990) · Developmental Psychology · doi:10.1037/0012-1649.26.1.68 · Cited by 106
Implicit Learning in Children Is Not Related to Age: Evidence from Drawing Behavior
Annie Vinter, A., & Perruchet, P. (2000) · Child Development · doi:10.1111/1467-8624.00225 · Cited by 102
Towards an explicit account of implicit learning
Forkstam, C., & Petersson, K. M. (2005) · Current Opinion in Neurology · doi:10.1097/01.wco.0000171951.82995.c4 · Cited by 97
Naito, M. (1990) · Journal of Experimental Child Psychology · doi:10.1016/0022-0965(90)90081-i · Cited by 89
Implicit learning: Sensitive to age but not IQ
Maybery, M. T., Taylor, M. J., & O’Brien-Malone, A. (1995) · Australian Journal of Psychology · doi:10.1080/00049539508258763 · Cited by 87
Remembering versus Knowing the Past: Children′s Explicit and Implicit Memories for Pictures
Drummey, A. B., & Newcombe, N. S. (1995) · Journal of Experimental Child Psychology · doi:10.1006/jecp.1995.1025 · Cited by 86
Development of the functional visual field
Clohessy, A. B., Posner, M. I., & Rothbart, M. K. (2001) · Acta Psychologica · doi:10.1016/s0001-6918(00)00026-3 · Cited by 81
The formation of expectations in early infancy
Haith, M. M., Wentworth, N., & Canfield, R. L. (1993) · Cited by 76
Implicit learning differences: A question of developmental level?
Fletcher, J. M., Maybery, M. T., & Bennett, S. A. (2000) · Journal of Experimental Psychology Learning Memory and Cognition · doi:10.1037//0278-7393.26.1.246 · Cited by 75
Procedural and Declarative Memory: A Developmental Study
Digiulio, D. V., Seidenberg, M., O'Leary, D. S., & Raz, N. (1994) · Brain and Cognition · doi:10.1006/brcg.1994.1024 · Cited by 73
If memory serves, will language? Later verbal accessibility of early memories
Bauer, P. J., Kroupina, M. G., Schwade, J. A., Dropik, P. L., & Wewerka, S. (1998) · Development and Psychopathology · doi:10.1017/s0954579498001801 · Cited by 71
Preschool period development of implicit and explicit remembering
Greenbaum, J., & Graf, P. (1989) · Bulletin of the Psychonomic Society · doi:10.3758/bf03334643 · Cited by 64
Cognitive-motor learning in Parkinson's disease.
Haaland, K. Y., Harrington, D. L., O'Brien, S., & Hermanowicz, N. S. (1997) · Neuropsychology · doi:10.1037//0894-4105.11.2.180 · Cited by 51
The Context of Uncertainty Modulates the Subcortical Response to Predictability
Bischoff‐Grethe, A., Martin, M. M., Mao, H., & Berns, G. S. (2001) · Journal of Cognitive Neuroscience · doi:10.1162/089892901753165881 · Cited by 38
Nelson, C. A. (1998) · Preventive Medicine · doi:10.1006/pmed.1998.0272 · Cited by 32
Developments In Early Recall Memory: Normative Trends and Individual Differences
Bauer, P. J., Burch, M. M., & Kleinknecht, E. (2003) · Advances in child development and behavior · doi:10.1016/s0065-2407(02)80040-4 · Cited by 19
The interplay of learning and development in shaping neural organization
Dick, F., Leech, R., Moses, P., & Saccuman, M. C. (2005) · Developmental Science · doi:10.1111/j.1467-7687.2005.00457.x · Cited by 12
Smith, P. H., Loboschefski, T. W., Davidson, B. K., & Dixon, W. E. (1997) · Infant Behavior and Development · doi:10.1016/s0163-6383(97)90044-8 · Cited by 8
Herbster (1997) · doi:10.1002/(sici)1097-0193(1997)5:2
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Metadata
- Authors
- Thomas, K. M., Hunt, R. H., Vizueta, N., Sommer, T., Durston, S., Yang, Y., & Worden, M. S.
- Affiliations
- University of Minnesota (US)
- Cornell University (US)
- Venue
- Journal of Cognitive Neuroscience
- Publisher
- MIT Press - Journals
- Published
- 2004-10-01
- Volume
- 16
- Issue
- 8
- Pages
- 1339-1351
- ISSN
- 0898-929X (ISSN-L)
- 1530-8898
- OpenAlex
- W2107564662
- Cited by
- 260
- References
- 70
- Citations by year
- 2026: 7 · 2025: 5 · 2024: 11 · 2023: 4 · 2022: 9 · 2021: 9 · 2020: 12 · 2019: 9 · 2018: 14 · 2017: 17 · 2016: 14 · 2015: 16 · 2014: 20 · 2013: 17 · 2012: 18
- FWCI
- 4.88
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Cognitive Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Institute of Mental Health (K01MH002024, K01 MH02024)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Keywords
- implicit sequence learning, developmental differences, children, adults, serial reaction time task, frontostriatal circuits, caudate nucleus, hippocampus, putamen, premotor cortex
- MeSH terms
- Adult, Analysis of Variance, Brain, Brain Mapping, Cerebral Cortex, Child, Child Development, Female, Hippocampus, Humans, Magnetic Resonance Imaging, Male, Pattern Recognition, Visual, Psychomotor Performance, Putamen, Reaction Time, Reference Values, Serial Learning
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