Reward-related Reversal Learning after Surgical Excisions in Orbito-frontal or Dorsolateral Prefrontal Cortex in Humans

Hornak, J.; O'Doherty, J.; Bramham, J.; Rolls, E. T.; Morris, R. G.; Bullock, P. R.; Polkey, C. E.

doi:10.1162/089892904322926791

Reward-related Reversal Learning after Surgical Excisions in Orbito-frontal or Dorsolateral Prefrontal Cortex in Humans

Neurophysiological studies in primates and neuroimaging studies in humans suggest that the orbito-frontal cortex is involved in representing the reward value of stimuli and in the rapid learning and relearning of associations between visual stimuli and rewarding or punishing outcomes. In the pres…