Cited by 6,746Respiratory Support and MechanismsNeonatal Respiratory Health ResearchSepsis Diagnosis and Treatment

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The American-European Consensus Conference On Ards. Definitions, Mechanisms, Relevant Outcomes, And Clinical Trial Coordination

Bernard, G R, Artigas, A, Brigham, K L, Carlet, J, Falke, K, Hudson, L, Lamy, M, Legall, J R, Morris, A, Spragg, R·1994·American journal of respiratory and critical care medicine

DOI 10.1164/ajrccm.149.3.7509706

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Abstract

The acute respiratory distress syndrome (ARDS), a process of nonhydrostatic pulmonary edema and hypoxemia associated with a variety of etiologies, carries a high morbidity, mortality (10 to 90%), and financial cost. The reported annual incidence in the United States is 150,000 cases, but this figure has been challenged, and it may be different in Europe. Part of the reason for these uncertainties are the heterogeneity of diseases underlying ARDS and the lack of uniform definitions for ARDS. Thus, those who wish to know the true incidence and outcome of this clinical syndrome are stymied. The American-European Consensus Committee on ARDS was formed to focus on these issues and on the pathophysiologic mechanisms of the process. It was felt that international coordination between North America and Europe in clinical studies of ARDS was becoming increasingly important in order to address the recent plethora of potential therapeutic agents for the prevention and treatment of ARDS.

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APACHE II-A Severity of Disease Classification System
Knaus, W. A., Draper, E. A., Wagner, D. P., & Zimmerman, J. E. (1986) · Critical Care Medicine · doi:10.1097/00003246-198608000-00028 · Cited by 13,379
ACUTE RESPIRATORY DISTRESS IN ADULTS
Ashbaugh, D. G., Bigelow, D. B., Petty, T. L., & Levine, B. D. (1967) · The Lancet · doi:10.1016/s0140-6736(67)90168-7 · Cited by 4,283
The APACHE III Prognostic System
Teres, D., & Lemeshow, S. A. (1992) · CHEST Journal · doi:10.1378/chest.102.6.1919b · Cited by 2,896
An Expanded Definition of the Adult Respiratory Distress Syndrome
Murray, J. F., Matthay, M. A., Luce, J. M., & Flick, M. R. (1988) · American Review of Respiratory Disease · doi:10.1164/ajrccm/138.3.720 · Cited by 2,641
A simplified acute physiology score for ICU patients
Gall, J. L., Loirat, P., Alpérovitch, A., GLASER, P., Granthil, C., Mathieu, D., MERCIER, P., THOMAS, R., & Villers, D. (1984) · Critical Care Medicine · doi:10.1097/00003246-198411000-00012 · Cited by 1,247
High-Dose Corticosteroids in Patients with the Adult Respiratory Distress Syndrome
Bernard, G. R., Luce, J. M., Sprung, C. L., Rinaldo, J. E., Tate, R. M., Sibbald, W. J., Kariman, K., Higgins, S. B., Bradley, R., Metz, C. A., et al. (1987) · New England Journal of Medicine · doi:10.1056/nejm198712173172504 · Cited by 927
Self-citation
Causes of Mortality in Patients With the Adult Respiratory Distress Syndrome
(1986) · Journal of Critical Care · doi:10.1016/s0883-9441(86)80119-8 · Cited by 801
Adult Respiratory Distress Syndrome: Risk with Common Predispositions
Fowler, A. A., HAMMAN, R. F., GOOD, J. T., BENSON, K. N., BAIRD, M., EBERLE, D. J., PETTY, T. L., & HYERS, T. M. (1983) · Annals of Internal Medicine · doi:10.7326/0003-4819-98-5-593 · Cited by 793
The Adult Respiratory Distress Syndrome
Petty, T. L., & Ashbaugh, D. G. (1971) · CHEST Journal · doi:10.1378/chest.60.3.233 · Cited by 779
The ACCP-SCCM Consensus Conference on Sepsis and Organ Failure
Bone, R. C., Sibbald, W. J., & Sprung, C. L. (1992) · CHEST Journal · doi:10.1378/chest.101.6.1481 · Cited by 750

Show all 20 references

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Effect of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in patients with acute respiratory distress syndrome
Gadek, J. E., DeMichele, S. J., Karlstad, M. D., Pacht, E. R., Donahoe, M., Albertson, T. E., Van Hoozen, C., Wennberg, A. K., Nelson, J. L., & Noursalehi, M. (1999) · Critical Care Medicine · doi:10.1097/00003246-199908000-00001 · Cited by 757
From evidence to clinical practice: Effective implementation of therapeutic hypothermia to improve patient outcome after cardiac arrest*
Oddo, M., Schaller, M., Feihl, F., Ribordy, V., & Liaudet, L. (2006) · Critical Care Medicine · doi:10.1097/01.ccm.0000221922.08878.49 · Cited by 590
Early Identification of Patients at Risk of Acute Lung Injury: Evaluation of Lung Injury Prediction Score in a Multicenter Cohort Study
Gajic, O., Dabbagh, O. C., Park, P. K., Adesanya, A. O., Chang, S. Y., Hou, P. C., Anderson, H., Hoth, J. J., Mikkelsen, M. E., Gentile, N., et al. (2010) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201004-0549oc · Cited by 604
Aerosolized Surfactant in Adults with Sepsis-Induced Acute Respiratory Distress Syndrome
Anzueto, A., Baughman, R. P., Guntupalli, K. K., Weg, J. G., Wiedemann, H. P., Artigas, A., Lemaire, F., Long, W. A., Zaccardelli, D., & Pattishall, E. N. (1996) · New England Journal of Medicine · doi:10.1056/nejm199605303342201 · Cited by 589
Self-citation
The ALIEN study: incidence and outcome of acute respiratory distress syndrome in the era of lung protective ventilation
on behalf of the ALIEN Network, Villar, J., Blanco, J., Añón, J. M., Santos-Bouza, A., Blanch, L. L., Ambrós, A., Gandía, F., Carriedo, D., Mosteiro, F., et al. (2011) · Intensive Care Medicine · doi:10.1007/s00134-011-2380-4 · Cited by 598
Clinical review: Severe malaria.
Trampuž, A., Jereb, M., Muzlovič, I., & Prabhu, R. M. (2003) · Critical Care · doi:10.1186/cc2183 · Cited by 623
Tidal Volume Lower than 6 ml/kg Enhances Lung Protection
Terragni, P., Sorbo, L. D., Mascia, L., Urbino, R., Martin, E. L., Birocco, A., Faggiano, C., Quintel, M., Gattinoni, L., & Ranieri, V. M. (2009) · Anesthesiology · doi:10.1097/aln.0b013e3181b764d2 · Cited by 574
Lower tidal volume strategy (≈3 ml/kg) combined with extracorporeal CO2 removal versus ‘conventional’ protective ventilation (6 ml/kg) in severe ARDS
Bein, T., Weber‐Carstens, S., Goldmann, A., Müller, T. M., Staudinger, T., Brederlau, J., Muellenbach, R. M., Dembinski, R., Graf, B. M., Wewalka, M., et al. (2013) · Intensive Care Medicine · doi:10.1007/s00134-012-2787-6 · Cited by 577
Recruitment and Derecruitment during Acute Respiratory Failure
Crotti, S., MASCHERONI, D., Caironi, P., Pelosi, P. P., RONZONI, G., Mondino, M. G., Marini, J. J., & Gattinoni, L. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.164.1.2007011 · Cited by 572
Transfusion-related acute lung injury: incidence and risk factors
Toy, P. T. C. Y., Gajic, O., Bacchetti, P., Looney, M. R., Gropper, M. A., Hubmayr, R. D., Lowell, C. A., Norris, P. J., Murphy, E. L., Weiskopf, R. B., et al. (2011) · Blood · doi:10.1182/blood-2011-08-370932 · Cited by 577
Prone ventilation reduces mortality in patients with acute respiratory failure and severe hypoxemia: Systematic review and meta-analysis.
Sud, S., Friedrich, J. O., Taccone, P., Polli, F., Adhikari, N. K. J., Latini, R., Pesenti, A., Guérin, C., Mancebo, J., Curley, M. A. Q., et al. (2010) · Intensive Care Medicine · doi:10.1007/s00134-009-1748-1 · Cited by 563
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D’Alessio, F. R., Tsushima, K., Aggarwal, N. R., West, E. E., Willett, M. H., Britos, M. F., Pipeling, M. R., Brower, R. G., Tuder, R. M., McDyer, J. F., et al. (2009) · Journal of Clinical Investigation · doi:10.1172/jci36498 · Cited by 564
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Mancebo, J., Fernández, R., Blanch, L. L., Rialp, G., Gordo, F., Ferrer, M., Arméstar, F., Garro, P., Ricart, P., Vallverdú, I., et al. (2006) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200503-353oc · Cited by 569
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Taccone, P., Pesenti, A. M., Latini, R., Polli, F., Vagginelli, F., Mietto, C., Caspani, L., Raimondi, F., Bordone, G., Iapichino, G., et al. (2009) · JAMA · doi:10.1001/jama.2009.1614 · Cited by 564
Statistical evaluation of ventilator-free days as an efficacy measure in clinical trials of treatments for acute respiratory distress syndrome
Schoenfeld, D., & Bernard, G. R. (2002) · Critical Care Medicine · doi:10.1097/00003246-200208000-00016 · Cited by 560
Self-citation
Clinical practice guideline: Red blood cell transfusion in adult trauma and critical care*
Napolitano, L. M., Kurek, S. J., Luchette, F. A., Corwin, H. L., Barie, P. S., Tisherman, S. A., Hébert, P. C., Anderson, G. L., Bard, M. R., Bromberg, W. J., et al. (2009) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181b39f1b · Cited by 560
Chest sonography: a useful tool to differentiate acute cardiogenic pulmonary edema from acute respiratory distress syndrome
Copetti, R., Soldati, G., & Copetti, P. (2008) · Cardiovascular Ultrasound · doi:10.1186/1476-7120-6-16 · Cited by 557
The Acute Respiratory Distress Syndrome
Kollef, M. H., & Schuster, D. P. (1995) · New England Journal of Medicine · doi:10.1056/nejm199501053320106 · Cited by 551
Meta-analysis of hemodynamic optimization in high-risk patients*
Kern, J. W., & Shoemaker, W. C. (2002) · Critical Care Medicine · doi:10.1097/00003246-200208000-00002 · Cited by 550
Lung Pathology in Fatal Novel Human Influenza A (H1N1) Infection
Mauad, T., Hajjar, L. A., Callegari, G. D., da Silva, L. F. F., Schout, D., Galas, F. R. B. G., Alves, V. A. F., Malheiros, D. M. A. C., Auler, J. O. C., Ferreira, A. F., et al. (2010) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200909-1420oc · Cited by 547
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Tandon, P., & García–Tsao, G. (2008) · Seminars in Liver Disease · doi:10.1055/s-2008-1040319 · Cited by 549
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Nathens, A. B., Neff, M. J., Jurkovich, G. J., Klotz, P., Farver, K., RUZINSKI, J. T., Radella, F., Garcia, I. A., & Maier, R. V. (2002) · Annals of Surgery · doi:10.1097/00000658-200212000-00014 · Cited by 544
Mortality Rates for Patients With Acute Lung Injury/ARDS Have Decreased Over Time
Zambon, M., & Vincent, J. (2008) · CHEST Journal · doi:10.1378/chest.07-2134 · Cited by 541
Rosuvastatin for Sepsis-Associated Acute Respiratory Distress Syndrome
The National Heart, L. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1401520 · Cited by 533
The epidemiology of the systemic inflammatory response
Brun‐Buisson, C. (2000) · Intensive Care Medicine · doi:10.1007/s001340051121 · Cited by 534
Acute Kidney Injury
Calzavacca, P., Licari, E., & Bellomo, R. (2009) · Springer eBooks · doi:10.1007/978-0-387-77893-8_38 · Cited by 532
The Development of Acute Lung Injury Is Associated with Worse Neurologic Outcome in Patients with Severe Traumatic Brain Injury
Holland, M. C., Mackersie, R. C., Morabito, D. J., Campbell, A. R., Kivett, V. A., Patel, R., Erickson, V. R., & Pittet, J. (2003) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/01.ta.0000071620.27375.be · Cited by 531
A multiple-center survey on the use in clinical practice of noninvasive ventilation as a first-line intervention for acute respiratory distress syndrome*
Antonelli, M. M., Conti, G., Esquinas, A. M., Montini, L. M., Maggiore, S. M., Bello, G., Rocco, M., Maviglia, R., Pennisi, M. A., Díaz, G. G., et al. (2006) · Critical Care Medicine · doi:10.1097/01.ccm.0000251821.44259.f3 · Cited by 530
Effect of Erythropoietin and Transfusion Threshold on Neurological Recovery After Traumatic Brain Injury
Robertson, C. S., Hannay, H. J., Yamal, J., Gopinath, S. P., Goodman, J. C., Tilley, B. C., Baldwin, A., Rivera‐Lara, L., Saucedo‐Crespo, H., Ahmed, O., et al. (2014) · JAMA · doi:10.1001/jama.2014.6490 · Cited by 524
Guidelines on the management of acute respiratory distress syndrome
Griffiths, M., McAuley, D. F., Perkins, G. D., Barrett, N. A., Blackwood, B., Boyle, A. J., Chee, N., Connolly, B. A., Dark, P. M., Finney, S. J., et al. (2019) · BMJ Open Respiratory Research · doi:10.1136/bmjresp-2019-000420 · Cited by 519
“45 This review included patients with ARDS, sepsis and SIRS, although subgroup data were available for ARDS.”
BackgroundMethodInfluential
Effects of the Prone Position on Respiratory Mechanics and Gas Exchange during Acute Lung Injury
Pelosi, P. P., Tubiolo, D., MASCHERONI, D., Vicardi, P., Crotti, S., Valenza, F., & Gattinoni, L. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.157.2.97-04023 · Cited by 509
Treatment of Acute Hypoxemic Nonhypercapnic Respiratory Insufficiency With Continuous Positive Airway Pressure Delivered by a Face Mask
Delclaux, C., L’Her, E., Alberti, C., Mancebo, J., Abroug, F., Conti, G., Guérin, C., Schortgen, F., Lefort, Y., Antonelli, M. M., et al. (2000) · JAMA · doi:10.1001/jama.284.18.2352 · Cited by 511
Extracorporeal Membrane Oxygenation for Pandemic Influenza A(H1N1)–induced Acute Respiratory Distress Syndrome
Pham, T. O., Combes, A., Rozé, H., Chevret, S., Mercat, A., Roch, A., Mourvillier, B., Ara-Somohano, C., Bastien, O. H., Zogheib, E. H., et al. (2012) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201205-0815oc · Cited by 496
Ventilation with lower tidal volumes as compared with conventional tidal volumes for patients without acute lung injury: a preventive randomized controlled trial
Determann, R. M., Royakkers, A. A. N. M., Wolthuis, E. K., Vlaar, A. P. J., Choi, G., Paulus, F., Hofstra, J.-J. H., de Graaff, M. J., Korevaar, J. C., & Schultz, M. J. (2010) · Critical Care · doi:10.1186/cc8230 · Cited by 497
Identification of Patients With Acute Lung Injury. Predictors of Mortality
Doyle, R. L., Szaflarski, N. L., Modin, G. W., Wiener-Kronish, J. P., & Matthay, M. A. (1995) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.152.6.8520742 · Cited by 494
Enteral Omega-3 Fatty Acid, γ-Linolenic Acid, and Antioxidant Supplementation in Acute Lung Injury
Rice, T. W. (2011) · JAMA · doi:10.1001/jama.2011.1435 · Cited by 552
Acute renal impairment in coronavirus-associated severe acute respiratory syndrome
Chu, K. H., Tsang, W. K., Tang, C. S.-O., Lam, M. F., Lai, F. M., To, K. F., Fung, S. K. S., Tang, H. L., Yan, W., Hilda Wai-Han, C. H. A. N., et al. (2005) · Kidney International · doi:10.1111/j.1523-1755.2005.67130.x · Cited by 483
Epidemiology and Outcomes of Acute Lung Injury
Rubenfeld, G. D., & Herridge, M. S. (2007) · CHEST Journal · doi:10.1378/chest.06-1976 · Cited by 483
Effects of Recruiting Maneuvers in Patients with Acute Respiratory Distress Syndrome Ventilated with Protective Ventilatory Strategy
Grasso, S., Mascia, L., Turco, M. D., Malacarne, P., Giunta, F., Brochard, L. J., Slutsky, A. S., & Ranieri, V. M. (2002) · Anesthesiology · doi:10.1097/00000542-200204000-00005 · Cited by 480
The American–European Consensus Conference on ARDS, Part 2: Ventilatory, Pharmacologic, Supportive Therapy, Study Design Strategies, and Issues Related to Recovery and Remodeling
Artigas, A., Bernard, G. R., Carlet, J. M., Dreyfuss, D., Gattinoni, L., Hudson, L. D., Lamy, M., Marini, J. J., Matthay, M. A., Pinsky, M. R., et al. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.157.4.ats2-98 · Cited by 471
Self-citation
Superior vena caval collapsibility as a gauge of volume status in ventilated septic patients
Vieillard‐Baron, A., Chergui, K., Rabiller, A., Peyrouset, O., Page, B., Beauchet, A., & Jardin, F. (2004) · Intensive Care Medicine · doi:10.1007/s00134-004-2361-y · Cited by 478
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Stapleton, R. D., Wang, B. M., Hudson, L. D., Rubenfeld, G. D., Caldwell, E., & Steinberg, K. P. (2005) · CHEST Journal · doi:10.1378/chest.128.2.525 · Cited by 475
Self-citation
Pathophysiological roles of interleukin-8/CXCL8 in pulmonary diseases
Mukaida, N. (2003) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00233.2002 · Cited by 474
Maladaptive role of neutrophil extracellular traps in pathogen-induced lung injury
Lefrançais, E., Mallavia, B., Zhuo, H., Calfee, C. S., & Looney, M. R. (2018) · JCI Insight · doi:10.1172/jci.insight.98178 · Cited by 492
“We used the American-European Consensus Conference (AECC) definition of ARDS, since this definition allows inclusion of patients who are not mechanically ventilated (55).”
Method
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McAuley, D. F., Laffey, J. G., O’Kane, C. M., Perkins, G. D., Mullan, B. A., Trinder, T. J., Johnston, P., Hopkins, P. A., Johnston, A. J., McDowell, C., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1403285 · Cited by 479
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Uchida, T., Shirasawa, M., Ware, L. B., 小島, 勝., Hata, Y., Makita, K., Mednick, G., Matthay, Z. A., & Matthay, M. A. (2006) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200509-1477oc · Cited by 468
Risk Factors for Acute Lung Injury After Thoracic Surgery for Lung Cancer
Licker, M. J., de Perrot, M. E., Spiliopoulos, A., Robert, J. H., Diaper, J., Chevalley, C., & Tschopp, J. (2003) · Anesthesia & Analgesia · doi:10.1213/01.ane.0000087799.85495.8a · Cited by 465
Effect of nitric oxide on oxygenation and mortality in acute lung injury: systematic review and meta-analysis
Adhikari, N. K. J., Burns, K. E. A., Friedrich, J. O., Granton, J. T., Cook, D. J., & Meade, M. O. (2007) · BMJ · doi:10.1136/bmj.39139.716794.55 · Cited by 461
Guidelines for the management of acute pancreatitis
Toouli, J., Brooke‐Smith, M. E., Bassi, C., Carr-Locke, D. L., Telford, J. J., Freeny, P. C., IMRIE, C. W., & Tandon, R. (2002) · Journal of Gastroenterology and Hepatology · doi:10.1046/j.1440-1746.17.s1.2.x · Cited by 461
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Bellomo, R., Kellum, J. A., & Ronco, C. (2001) · Intensive Care Medicine · doi:10.1007/s00134-001-1120-6 · Cited by 459
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Vieillard‐Baron, A., Schmitt, J.-M., Augarde, R., Fellahi, J.-L., Prin, S., Page, B., Beauchet, A., & Jardin, F. (2001) · Critical Care Medicine · doi:10.1097/00003246-200108000-00009 · Cited by 458
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Bersten, A. D., Edibam, C., Hunt, T. D., & Moran, J. L. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.165.4.2101124 · Cited by 456
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Ballas, S. K., Lieff, S., Benjamin, L. J., Dampier, C., Heeney, M. M., Hoppe, C. C., Johnson, C. S., Rogers, Z. R., Smith‐Whitley, K., Wang, W. C., et al. (2009) · American Journal of Hematology · doi:10.1002/ajh.21550 · Cited by 454
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Riviello, E. D., Kiviri, W., Twagirumugabe, T., Mueller, A., Banner‐Goodspeed, V., Officer, L., Novack, V., Mutumwinka, M., Talmor, D. S., & Fowler, R. (2015) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201503-0584oc · Cited by 463
Regulatory role for macrophage migration inhibitory factor in acute respiratory distress syndrome
Donnelly, S. C., Haslett, C., Reid, P. T., Grant, I. S., Wallace, W. A., Metz, C. N., Bruce, L. J., & Bucala, R. (1997) · Nature Medicine · doi:10.1038/nm0397-320 · Cited by 448
Conservative fluid management or deresuscitation for patients with sepsis or acute respiratory distress syndrome following the resuscitation phase of critical illness: a systematic review and meta-analysis
Silversides, J. A., Major, E., Ferguson, A. J., Mann, E. E., McAuley, D. F., Marshall, J. C., Blackwood, B., & Fan, E. (2016) · Intensive Care Medicine · doi:10.1007/s00134-016-4573-3 · Cited by 458
Clinical predictors of and mortality in acute respiratory distress syndrome: Potential role of red cell transfusion*
Gong, M. N., Thompson, B., Williams, P. L., Pothier, L., Boyce, P. D., & Christiani, D. C. (2005) · Critical Care Medicine · doi:10.1097/01.ccm.0000165566.82925.14 · Cited by 439
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Nakahira, K., Kyung, S.-Y., Rogers, A. J., Gazourian, L., Youn, S., Massaro, A. F., Quintana, C., Osorio, J. C., Wang, Z., Zhao, Y., et al. (2013) · PLoS Medicine · doi:10.1371/journal.pmed.1001577 · Cited by 445
“In addition to baseline demographic data, assessments of sepsis and acute respiratory distress syndrome (ARDS) were performed, and Acute Physiology and Chronic Health Evaluation (APACHE) II scores were measured [18–20].”
Method
The Importance of Fluid Management in Acute Lung Injury Secondary to Septic Shock
Murphy, C. V., Schramm, G. E., Doherty, J. A., Reichley, R. M., Gajic, O., Afessa, B., Micek, S. T., & Kollef, M. H. (2009) · CHEST Journal · doi:10.1378/chest.08-2706 · Cited by 442
Inhalation of nitric oxide in acute lung injury: results of a European multicentre study
Lundin, S., Mang, H., Smithies, M. N., Stenqvist, O., FROSTELL, C. G., & for the European Study Group of Inhaled Nitric Oxide (1999) · Intensive Care Medicine · doi:10.1007/s001340050982 · Cited by 433
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Zilberberg, M. D., & Epstein, S. K. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.157.4.9704088 · Cited by 428
Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study
Khemani, R. G., Smith, L., López‐Fernández, Y. M., Kwok, J., Morzov, R., Klein, M. J., Yehya, N., Willson, D. F., Kneyber, M. C. J., Lillie, J., et al. (2018) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(18)30344-8 · Cited by 434
Spontaneous Breathing During Ventilatory Support Improves Ventilation–Perfusion Distributions in Patients with Acute Respiratory Distress Syndrome
Putensen, C., Mutz, N., Putensen-Himmer, G., & Zinserling, J. (1999) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.159.4.9806077 · Cited by 428
Transfusion-related Acute Lung Injury in the Critically Ill
Gajic, O., Rana, R., Winters, J. L., Yılmaz, M., Mendez, J. L., Rickman, O. B., O’Byrne, M. M., Evenson, L. K., Malinchoc, M., DeGoey, S. R., et al. (2007) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200702-271oc · Cited by 430
Community-Acquired Bloodstream Infection in Critically Ill Adult Patients
Vallés, J., Rello, J., Ochagavía, A., Garnacho, J., & Alcalá, M. (2003) · CHEST Journal · doi:10.1378/chest.123.5.1615 · Cited by 430
Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management
Gorman, E. A., O’Kane, C. M., & McAuley, D. F. (2022) · The Lancet · doi:10.1016/s0140-6736(22)01439-8 · Cited by 436
A Trial of Antioxidants N-acetylcysteine and Procysteine in ARDS
Bernard, G. R., Wheeler, A. P., Arons, M. M., Morris, P. E., Paz, H. L., Russell, J. A., & Wright, P. E. (1997) · CHEST Journal · doi:10.1378/chest.112.1.164 · Cited by 429
Self-citation
Treatment of severe acute respiratory syndrome with lopinavir/ritonavir: a multicentre retrospective matched cohort study.
Chan, K., Lai, S. T., Chu, C., Tsui, E. L. H., Tam, C. Y., Wong, M. M.-L., Tse, M. W., Que, T. L., Peiris, M. J. S., Sung, J. J. �., et al. (2003) · PubMed · Cited by 423
ECMO for severe ARDS: systematic review and individual patient data meta-analysis
Combes, A., Peek, G. J., Hajage, D., Hardy, P., Abrams, D. C., Schmidt, M., Dechartres, A., & Elbourne, D. R. (2020) · Intensive Care Medicine · doi:10.1007/s00134-020-06248-3 · Cited by 431
Comparison of the Berlin Definition for Acute Respiratory Distress Syndrome with Autopsy
Thille, A. W., Esteban, A., Fernández-Segoviano, P., Rodríguez, J., Aramburu, J., Peñuelas, Ó., Cortés‐Puch, I., Cardinal‐Fernández, P., Lorente, J. A., & Frutos–Vivar, F. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201211-1981oc · Cited by 426
The monocrotaline model of pulmonary hypertension in perspective
Gomez‐Arroyo, J. G., Farkas, L., Alhussaini, A. A., Farkas, D., Kraskauskas, D., Voelkel, N. F., & Bogaard, H. J. (2011) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00212.2011 · Cited by 426
Acute Respiratory Distress Syndrome in Critically Ill Patients With Severe Acute Respiratory Syndrome
Lew, T. W. K. (2003) · JAMA · doi:10.1001/jama.290.3.374 · Cited by 423
PULMONARY PATHOLOGY OF ACUTE RESPIRATORY DISTRESS SYNDROME
Tomashefski, J. F. (2000) · Clinics in Chest Medicine · doi:10.1016/s0272-5231(05)70158-1 · Cited by 423
Pulmonary Complications Following Lung Resection
Steéphan, F., Boucheseiche, S., Hollande, J., Flahault, A., Cheffi, A., Bazelly, B., & Bonnet, F. J. (2000) · CHEST Journal · doi:10.1378/chest.118.5.1263 · Cited by 422
The alveolar space is the site of intense inflammatory and profibrotic reactions in the early phase of acute respiratory distress syndrome
Pugin, J., Verghese, G. M., Widmer, M.-C., & Matthay, M. A. (1999) · Critical Care Medicine · doi:10.1097/00003246-199902000-00036 · Cited by 421
Resuscitation fluid use in critically ill adults: an international cross-sectional study in 391 intensive care units
Finfer, S. R., Liu, B. C., Taylor, C. B., Bellomo, R., Billot, L., Cook, D., Du, B., McArthur, C. J., Myburgh, J., & SAFE TRIPS Investigators (2010) · Critical Care · doi:10.1186/cc9293 · Cited by 414
Serial Changes in Surfactant-associated Proteins in Lung and Serum before and after Onset of ARDS
Greene, K. E., Wright, J. R., Steinberg, K. P., RUZINSKI, J. T., Caldwell, E., WONG, W. B., Hull, W. M., Whitsett, J. A., Akino, T., Kuroki, Y., et al. (1999) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.160.6.9901117 · Cited by 419
Self-citation
Delayed Clearance of Viral Load and Marked Cytokine Activation in Severe Cases of Pandemic H1N1 2009 Influenza Virus Infection
To, K. K., Hung, I. F., Li, I. W. S., Lee, K., Koo, C., Yan, W., Liu, R. W., Ho, K., Chu, K., Watt, C., et al. (2010) · Clinical Infectious Diseases · doi:10.1086/650581 · Cited by 417
Lung injury and acute respiratory distress syndrome after cardiopulmonary bypass
Asimakopoulos, G., Smith, P., Ratnatunga, C., & Taylor, K. M. (1999) · The Annals of Thoracic Surgery · doi:10.1016/s0003-4975(99)00781-x · Cited by 415
Effect of Exogenous Surfactant (Calfactant) in Pediatric Acute Lung Injury A Randomized Controlled Trial
Willson, D. F. (2005) · JAMA · doi:10.1001/jama.293.4.470 · Cited by 418
Efficacy and safety of early prone positioning combined with HFNC or NIV in moderate to severe ARDS: a multi-center prospective cohort study
Ding, L., Wang, L., Ma, W., & He, H. (2020) · Critical Care · doi:10.1186/s13054-020-2738-5 · Cited by 430
“ARDS was initially reported with mortality as high as 90% [23] .”
Background
Effect of Recombinant Surfactant Protein C–Based Surfactant on the Acute Respiratory Distress Syndrome
Spragg, R. G., Lewis, J. F., Walmrath, H., Johannigman, J. A., Bellingan, G. J., Laterre, P., Witte, M. C., Richards, G. A., Rippin, G., Rathgeb, F., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa033181 · Cited by 417
Self-citation
Natural product derived phytochemicals in managing acute lung injury by multiple mechanisms
He, Y.-Q., Zhou, C., Yu, L., Wang, L., Deng, J.-L., Tao, Y., Zhang, F., & Chen, W. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.105224 · Cited by 415
Pediatric Acute Respiratory Distress Syndrome
Khemani, R. G., Smith, L., Zimmerman, J. J., & Erickson, S. J. (2015) · Pediatric Critical Care Medicine · doi:10.1097/pcc.0000000000000432 · Cited by 431
Oxidants and the pathogenesis of lung diseases
Ciencewicki, J., Trivedi, S., & Kleeberger, S. R. (2008) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2008.08.004 · Cited by 405
Epidemiology of invasive aspergillosis in critically ill patients: clinical presentation, underlying conditions, and outcomes
Taccone, F. S., den Abeele, A. V., Bulpa, P., Misset, B., Meersseman, W., Cardoso, T., Paiva, J.-A., Blasco-Navalpotro, M. Á., Laere, E. D., Dimοpoulos, G., et al. (2015) · Critical Care · doi:10.1186/s13054-014-0722-7 · Cited by 409
“Acute respiratory distress syndrome (ARDS) was defined according to the 1994 Consensus Conference criteria [27].”
BackgroundMethod
Description and clinical treatment of an early outbreak of severe acute respiratory syndrome (SARS) in Guangzhou, PR China
Zhao, Z. (2003) · Journal of Medical Microbiology · doi:10.1099/jmm.0.05320-0 · Cited by 406
Complications of Massive Transfusion
Sihler, K. C., & Napolitano, L. M. (2010) · CHEST Journal · doi:10.1378/chest.09-0252 · Cited by 405
Neutrophils as early immunologic effectors in hemorrhage- or endotoxemia-induced acute lung injury
Abraham, E. H., Carmody, A., Shenkar, R., & Arcaroli, J. J. (2000) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.2000.279.6.l1137 · Cited by 403
Neuromuscular blocking agents decrease inflammatory response in patients presenting with acute respiratory distress syndrome.
Forel, J.-M., Roch, A., Marin, V., Michelet, P., Demory, D., Blache, J.-L., Perrin, G., Gainnier, M., Bongrand, P., & Papazian, L. (2006) · Critical Care Medicine · doi:10.1097/01.ccm.0000239435.87433.0d · Cited by 400
Interleukin-8 (IL-8) and monocyte chemotactic and activating factor (MCAF/MCP-1), chemokines essentially involved in inflammatory and immune reactions
Mukaida, N., Harada, A., & Matsushima, K. (1998) · Cytokine & Growth Factor Reviews · doi:10.1016/s1359-6101(97)00022-1 · Cited by 401
Acute respiratory distress syndrome
Sweeney, R. M., & McAuley, D. F. (2016) · The Lancet · doi:10.1016/s0140-6736(16)00578-x · Cited by 421
Inhaled Nitric Oxide Therapy in Adults
Griffiths, M., & Evans, T. W. (2005) · New England Journal of Medicine · doi:10.1056/nejmra051884 · Cited by 397
Physiologic Effects of Noninvasive Ventilation during Acute Lung Injury
L’Her, E., Deye, N., Lellouche, F., Taillé, S., Demoule, A., Fraticelli, A. T., Mancebo, J., & Brochard, L. J. (2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200402-226oc · Cited by 394
Benefit of an enteral diet enriched with eicosapentaenoic acid and gamma-linolenic acid in ventilated patients with acute lung injury*
Singer, P., Theilla, M., Fisher, H., Gibstein, L., Grozovski, E., & Cohen, J. (2006) · Critical Care Medicine · doi:10.1097/01.ccm.0000206111.23629.0a · Cited by 393
The Acute Respiratory Distress Syndrome: From Mechanism to Translation
Han, S., & Mallampalli, R. K. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1402513 · Cited by 404
“aspiration, toxic inhalation, lung contusion, acute pancreatitis, trauma, transfusion, burn injury, and cardiopulmonary bypass surgery (3).”
Background
Reappraisal of Ventilator-Free Days in Critical Care Research
Yehya, N., Harhay, M. O., Curley, M. A. Q., Schoenfeld, D., & Reeder, R. (2019) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201810-2050cp · Cited by 395
“VFDs were considered for ARDS trials as early as the 1994 American-European Consensus Conference (10) and indeed offer several attractions.”
Background
Lung protective ventilation strategy for the acute respiratory distress syndrome
Petrucci, N., & Feo, C. D. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003844.pub4 · Cited by 390
Distinct Molecular Phenotypes of Direct vs Indirect ARDS in Single-Center and Multicenter Studies
Calfee, C. S., Janz, D. R., Bernard, G. R., May, A. K., Kangelaris, K. N., Matthay, M. A., & Ware, L. B. (2014) · CHEST Journal · doi:10.1378/chest.14-2454 · Cited by 395
Self-citation
Defining and classifying acute renal failure: from advocacy to consensus and validation of the RIFLE criteria
Bellomo, R., Kellum, J. A., & Ronco, C. (2006) · Intensive Care Medicine · doi:10.1007/s00134-006-0478-x · Cited by 388

Authors: Bernard, G. R., Artigas, A., Brigham, K. L., Carlet, J., Falke, K., Hudson, L., Lamy, M., Legall, J. R., Morris, A., & Spragg, R.
Affiliations: Vanderbilt University (US)
Vanderbilt University, Nashville, Tennessee
ORCID: Bernard, G R
Artigas, A
Carlet, J
Lamy, M
Morris, A
Venue: American journal of respiratory and critical care medicine
Publisher: Oxford University Press (OUP)
Published: 1994-03-01
Volume: 149
Issue: 3
Pages: 818-824
ISSN: 1073-449X (ISSN-L)
1535-4970
DOI: 10.1164/ajrccm.149.3.7509706
OpenAlex: W2161328469
Cited by: 6,746
References: 20
Citations by year: 2026: 54 · 2025: 112 · 2024: 107 · 2023: 119 · 2022: 126 · 2021: 164 · 2020: 158 · 2019: 184 · 2018: 156 · 2017: 192 · 2016: 238 · 2015: 241 · 2014: 289 · 2013: 341 · 2012: 364
FWCI: 80.47
Type: journal article
Language: en
Open access: closed
Licence: academic.oup.com/pages/standard-publication-reuse-rights (vor)
Locations: American Journal of Respiratory and Critical Care Medicine (publishedVersion)
PubMed (publishedVersion)
D-Scholarship@Pitt (University of Pittsburgh) (acceptedVersion)
Funders: National Institutes of Health (5r01hl043167-05, 5p50hl019153-22)
National Heart, Lung, and Blood Institute (NHLBI HL19153, NHLBI HL43167)
Topics: Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Neonatal Respiratory Health Research
Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Sepsis Diagnosis and Treatment
Keywords: acute respiratory distress syndrome, ARDS definition, ARDS pathophysiology, ARDS incidence, ARDS mortality, clinical trial coordination
MeSH terms: Americas, Clinical Protocols, Clinical Trials as Topic, Europe, Humans, Oxygen Inhalation Therapy, Prognosis, Radiography, Respiratory Distress Syndrome, Risk Factors, Incidence, Prevalence

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The American-European Consensus Conference On Ards. Definitions, Mechanisms, Relevant Outcomes, And Clinical Trial Coordination

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