Cited by 6,746Respiratory Support and MechanismsNeonatal Respiratory Health ResearchSepsis Diagnosis and Treatment

The DOI matches its Crossref record; 19 of the 20 references it cites were found in a registry or an index.

The American-European Consensus Conference On Ards. Definitions, Mechanisms, Relevant Outcomes, And Clinical Trial Coordination

Bernard, G R, Artigas, A, Brigham, K L, Carlet, J, Falke, K, Hudson, L, Lamy, M, Legall, J R, Morris, A, Spragg, R·1994·American journal of respiratory and critical care medicine

DOI 10.1164/ajrccm.149.3.7509706

Open this paper in CoChat — free account

Abstract

The acute respiratory distress syndrome (ARDS), a process of nonhydrostatic pulmonary edema and hypoxemia associated with a variety of etiologies, carries a high morbidity, mortality (10 to 90%), and financial cost. The reported annual incidence in the United States is 150,000 cases, but this figure has been challenged, and it may be different in Europe. Part of the reason for these uncertainties are the heterogeneity of diseases underlying ARDS and the lack of uniform definitions for ARDS. Thus, those who wish to know the true incidence and outcome of this clinical syndrome are stymied. The American-European Consensus Committee on ARDS was formed to focus on these issues and on the pathophysiologic mechanisms of the process. It was felt that international coordination between North America and Europe in clinical studies of ARDS was becoming increasingly important in order to address the recent plethora of potential therapeutic agents for the prevention and treatment of ARDS.

Integrity signals

Registry

Crossref · 10.1164/ajrccm.149.3.7509706

Cites

19 of 19 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

APACHE II-A Severity of Disease Classification System
Knaus, W. A., Draper, E. A., Wagner, D. P., & Zimmerman, J. E. (1986) · Critical Care Medicine · doi:10.1097/00003246-198608000-00028 · Cited by 13,379
ACUTE RESPIRATORY DISTRESS IN ADULTS
Ashbaugh, D. G., Bigelow, D. B., Petty, T. L., & Levine, B. D. (1967) · The Lancet · doi:10.1016/s0140-6736(67)90168-7 · Cited by 4,283
The APACHE III Prognostic System
Teres, D., & Lemeshow, S. A. (1992) · CHEST Journal · doi:10.1378/chest.102.6.1919b · Cited by 2,896
An Expanded Definition of the Adult Respiratory Distress Syndrome
Murray, J. F., Matthay, M. A., Luce, J. M., & Flick, M. R. (1988) · American Review of Respiratory Disease · doi:10.1164/ajrccm/138.3.720 · Cited by 2,641
A simplified acute physiology score for ICU patients
Gall, J. L., Loirat, P., Alpérovitch, A., GLASER, P., Granthil, C., Mathieu, D., MERCIER, P., THOMAS, R., & Villers, D. (1984) · Critical Care Medicine · doi:10.1097/00003246-198411000-00012 · Cited by 1,247
High-Dose Corticosteroids in Patients with the Adult Respiratory Distress Syndrome
Bernard, G. R., Luce, J. M., Sprung, C. L., Rinaldo, J. E., Tate, R. M., Sibbald, W. J., Kariman, K., Higgins, S. B., Bradley, R., Metz, C. A., et al. (1987) · New England Journal of Medicine · doi:10.1056/nejm198712173172504 · Cited by 927
Self-citation
Causes of Mortality in Patients With the Adult Respiratory Distress Syndrome
(1986) · Journal of Critical Care · doi:10.1016/s0883-9441(86)80119-8 · Cited by 801
Adult Respiratory Distress Syndrome: Risk with Common Predispositions
Fowler, A. A., HAMMAN, R. F., GOOD, J. T., BENSON, K. N., BAIRD, M., EBERLE, D. J., PETTY, T. L., & HYERS, T. M. (1983) · Annals of Internal Medicine · doi:10.7326/0003-4819-98-5-593 · Cited by 793
The Adult Respiratory Distress Syndrome
Petty, T. L., & Ashbaugh, D. G. (1971) · CHEST Journal · doi:10.1378/chest.60.3.233 · Cited by 779
The ACCP-SCCM Consensus Conference on Sepsis and Organ Failure
Bone, R. C., Sibbald, W. J., & Sprung, C. L. (1992) · CHEST Journal · doi:10.1378/chest.101.6.1481 · Cited by 750

Show all 20 references

Sorted by citations

Items 401–500 of 1,013

A Lung Computed Tomographic Assessment of Positive End-Expiratory Pressure–induced Lung Overdistension
Vieira, S. R. R., Puybasset, L., Richecoeur, J. R., Lü, Q., Cluzel, P., Gusman, P. B., Coriat, P., & Rouby, J. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.158.5.9802101 · Cited by 232
Reduced mortality in association with the acute respiratory distress syndrome (ARDS)
Abel, S. J. C., Finney, S. J., Brett, S. J., Keogh, B. F., Morgan, C., & Evans, T. W. (1998) · Thorax · doi:10.1136/thx.53.4.292 · Cited by 231
Clinical Characteristics and Outcomes of Obstetric Patients Requiring ICU Admission
Vásquez, D. N., Estenssoro, E., Canales, H. S., Reina, R., Sáenz, M. G., Neves, A. V. D., Toro, M. A., & Loudet, C. (2007) · CHEST Journal · doi:10.1378/chest.06-2388 · Cited by 227
Recruitment Maneuvers during Lung Protective Ventilation in Acute Respiratory Distress Syndrome
Villagra, A. L. R., Ochagavía, A., Vatua, S., Murias, G. E., Fernandez, M. D. M., López‐Aguilar, J., Fernández, R., & Blanch, L. L. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.165.2.2104092 · Cited by 230
Acute respiratory distress syndrome: new definition, current and future therapeutic options.
Fanelli, V., Vlachou, A., Ghannadian, S., Simonetti, U., Slutsky, A. S., & Zhang, H. (2013) · Europe PMC (PubMed Central) · doi:10.3978/j.issn.2072-1439.2013.04.05 · Cited by 235
Damage control resuscitation for patients with major trauma
Jansen, J. O., Thomas, R., Loudon, M. A., & Brooks, A. J. (2009) · BMJ · doi:10.1136/bmj.b1778 · Cited by 228
Assessing pulmonary permeability by transpulmonary thermodilution allows differentiation of hydrostatic pulmonary edema from ALI/ARDS
Monnet, X., Anguel, N., Osman, D., Hamzaoui, O., Richard, C., & Teboul, J. (2007) · Intensive Care Medicine · doi:10.1007/s00134-006-0498-6 · Cited by 233
Increased Circulating Endothelial Progenitor Cells Are Associated with Survival in Acute Lung Injury
Burnham, E. L., Taylor, W. R., Quyyumi, A. A., Rojas, M., Brigham, K. L., & Moss, M. M. (2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200410-1325oc · Cited by 227
Self-citation
Clinical aspects and cytokine response in severe H1N1 influenza A virus infection
Hagău, N., Slavcovici, A., Gonganau, D. N., Oltean, S., Dîrzu, D. S., Brezoszki, E. S., Maxim, M., Ciuce, C., Mleșnițe, M., Gavrus, R. L., et al. (2010) · Critical Care · doi:10.1186/cc9324 · Cited by 227
Acute Respiratory Distress Syndrome: CT Abnormalities at Long-term Follow-up
Desai, S. R., Wells, A. U., Rubens, M. B., Evans, T. W., & Hansell, D. M. (1999) · Radiology · doi:10.1148/radiology.210.1.r99ja2629 · Cited by 227
Expression and Function of the Chemokine Receptors CXCR1 and CXCR2 in Sepsis
Cummings, C., Martin, T. R., Frevert, C. W., Quan, J. M., Wong, V. A., Mongovin, S., Hagen, T. R., Steinberg, K. P., & Goodman, R. B. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.162.4.2341 · Cited by 226
Beneficial Hemodynamic Effects of Prone Positioning in Patients with Acute Respiratory Distress Syndrome
Jozwiak, M., Teboul, J., Anguel, N., Persichini, R., Silva, S., Chemla, D., Richard, C., & Monnet, X. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201303-0593oc · Cited by 229
“In conclusion, in patients with ARDS with protective ventilation, PP increased cardiac preload and reduced RV afterload.”
MethodInfluential
Pandemic 2009 Influenza A in Argentina: A Study of 337 Patients on Mechanical Ventilation
Estenssoro, E., Ríos, F. G., Apezteguía, C., Reina, R., Neira, J., Ceraso, D. H., Orlandi, C., Valentini, R., Tiribelli, N., Brizuela, M., et al. (2010) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/201001-0037oc · Cited by 230
Incidence and Outcomes of Pediatric Acute Lung Injury
Zimmerman, J. J., Akhtar, S. R., Caldwell, E., & Rubenfeld, G. D. (2009) · PEDIATRICS · doi:10.1542/peds.2007-2462 · Cited by 225
Long-term Outcomes of Pandemic 2009 Influenza A(H1N1)-Associated Severe ARDS
Luyt, C. E., Combes, A., Becquemin, M. H., Beigelman‐Aubry, C., Hatem, S. N., Brun, A., Zraik, N., Carrat, F., Greniér, P., Richard, J.-C., et al. (2012) · CHEST Journal · doi:10.1378/chest.11-2196 · Cited by 225
Definition and epidemiology of acute respiratory distress syndrome
Rezoagli, E., Fumagalli, R., & Bellani, G. (2017) · Annals of Translational Medicine · doi:10.21037/atm.2017.06.62 · Cited by 235
“The severity of hypoxia, defined the class of lung injury as ALI (PaO2/FiO2 ≤300) or ARDS (PaO2/FiO2 ≤200) (9).”
Background
Health-related Quality of Life after Acute Lung Injury
Weinert, C., Gross, C. R., KANGAS, J. R., BURY, C. L., & Marinelli, W. A. (1997) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.156.4.9611047 · Cited by 221
Severity of Pneumococcal Pneumonia Associated With Genomic Bacterial Load
Rello, J., Lisboa, T. C., Luján, M., Gallego, M., Kee, C., Kay, I. D., Lopez, D., & WATERER, G. W. (2009) · CHEST Journal · doi:10.1378/chest.09-0258 · Cited by 223
Adult Respiratory Distress Syndrome, Pneumonia, and Mortality following Thoracic Injury and a Femoral Fracture Treated Either with Intramedullary Nailing with Reaming or with a Plate. A Comparative Study*
Bosse, M. J., MacKenzie, E. J., Riemer, B. L., Brumback, R. J., McCarthy, M. L., Burgess, A. R., Gens, D. R., & Yasui, Y. (1997) · Journal of Bone and Joint Surgery · doi:10.2106/00004623-199706000-00001 · Cited by 224
Epidemiology of acute lung injury
Rubenfeld, G. D. (2003) · Critical Care Medicine · doi:10.1097/01.ccm.0000057904.62683.2b · Cited by 220
Comparison of SpO2 to PaO2 based markers of lung disease severity for children with acute lung injury*
Khemani, R. G., Thomas, N. J., Venkatachalam, V., Scimeme, J., Berutti, T. W., Schneider, J. B., Ross, P. A., Willson, D. F., Hall, M. W., & Newth, C. J. L. (2012) · Critical Care Medicine · doi:10.1097/ccm.0b013e31823bc61b · Cited by 223
Effect of 24-hour mandatory versus on-demand critical care specialist presence on quality of care and family and provider satisfaction in the intensive care unit of a teaching hospital*
Gajic, O., Afessa, B., Hanson, A. C., Krpata, T. S., Yılmaz, M., Mohamed, S., Rabatin, J. T., Evenson, L. K., Aksamit, T. R., Peters, S. G., et al. (2008) · Critical Care Medicine · doi:10.1097/01.ccm.0000297887.84347.85 · Cited by 222
Biomarkers of lung epithelial injury and inflammation distinguish severe sepsis patients with acute respiratory distress syndrome
Ware, L. B., Koyama, T., Zhao, Z., Janz, D. R., Wickersham, N. E., Bernard, G. R., May, A. K., Calfee, C. S., & Matthay, M. A. (2013) · Critical Care · doi:10.1186/cc13080 · Cited by 227
“Despite recent modifications [2] to the American European Consensus Conference (AECC) definition [3], the clinical definition of ARDS remains”
MethodInfluentialSelf-citation
Role of Flexible Bronchoscopy in Immunocompromised Patients With Lung Infiltrates
Jain, P., Sandur, S., Meli, Y. M., Arroliga, A. C., Stoller, J. K., & Mehta, A. C. (2004) · CHEST Journal · doi:10.1378/chest.125.2.712 · Cited by 222
The pulmonary physician in critical care * 6: The pathogenesis of ALI/ARDS
Bellingan, G. J. (2002) · Thorax · doi:10.1136/thorax.57.6.540 · Cited by 222
Platelet Transfusion During Liver Transplantation Is Associated with Increased Postoperative Mortality Due to Acute Lung Injury
Pereboom, I. T. A., de Boer, M. T., Haagsma, E. B., Hendriks, H. G. D., Lisman, T., & Porte, R. J. (2009) · Anesthesia & Analgesia · doi:10.1213/ane.0b013e3181948a59 · Cited by 222
Impact of intraoperative lung-protective interventions in patients undergoing lung cancer surgery
Licker, M. J., Diaper, J., Villiger, Y., Spiliopoulos, A., Licker, V., Robert, J. H., & Tschopp, J. (2009) · Critical Care · doi:10.1186/cc7762 · Cited by 221
Prevention of Endotracheal Suctioning-induced Alveolar Derecruitment in Acute Lung Injury
Maggiore, S. M., Lellouche, F., Pigeot, J., Taillé, S., Deye, N., Durrmeyer, X., Richard, J.-C., Mancebo, J., Lemaire, F., & Brochard, L. J. (2003) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200203-195oc · Cited by 221
Acute interstitial pneumonia
Bouros, D. E., Nicholson, A. G., Polychronopoulos, V., & du Bois, R. M. (2000) · European Respiratory Journal · doi:10.1034/j.1399-3003.2000.15b31.x · Cited by 221
Mechanical ventilation affects inflammatory mediators in patients undergoing cardiopulmonary bypass for cardiac surgery: A randomized clinical trial
Zupancich, E., Paparella, D., Turani, F., Münch, C. M., Rossi, A., Massaccesi, S., & Ranieri, V. M. (2005) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2004.11.061 · Cited by 220
Prospective Randomized Trial Comparing Pressure-Controlled Ventilation and Volume-Controlled Ventilation in ARDS
Esteban, A., Alía, I., Vidal, F. G., de Pablo, R., Suarez, J., González, G., & Blanco, J. (2000) · CHEST Journal · doi:10.1378/chest.117.6.1690 · Cited by 218
Physiological comparison of three spontaneous breathing trials in difficult-to-wean patients
Cabello, B., Thille, A. W., Roche‐Campo, F., Brochard, L. J., Gómez, F. J., & Mancebo, J. (2010) · Intensive Care Medicine · doi:10.1007/s00134-010-1870-0 · Cited by 219
A consensus redefinition of transfusion‐related acute lung injury
Vlaar, A. P. J., Toy, P. T. C. Y., Fung, M. K. Y., Looney, M. R., Juffermans, N. P., Bux, J., Bolton‐Maggs, P. H. B., Peters, A. L., Silliman, C. C., Kor, D. J., et al. (2019) · Transfusion · doi:10.1111/trf.15311 · Cited by 230
Acute respiratory distress syndrome
Confalonieri, M., Salton, F., & Fabiano, F. (2017) · European Respiratory Review · doi:10.1183/16000617.0116-2016 · Cited by 227
Volume-dependent compliance in ARDS: proposal of a new diagnostic concept
Mols, G., Brandes, I. F., Kessler, V., Lichtwarck‐Aschoff, M., Loop, T., Geiger, K. K., & Guttmann, J. (1999) · Intensive Care Medicine · doi:10.1007/s001340051016 · Cited by 218
Impact of Primary Graft Failure on Outcomes Following Lung Transplantation
Christie, J. D., Sager, J. S., Kimmel, S. E., Ahya, V. N., Gaughan, C., Blumenthal, N. P., & Kotloff, R. M. (2005) · CHEST Journal · doi:10.1378/chest.127.1.161 · Cited by 218
Incidence and Risk Factors for Lung Injury After Lung Cancer Resection
Alam, N. Z., Park, B. J., Wilton, A. S., Seshan, V., Bains, M. S., Downey, R. J., Flores, R. M., Rizk, N. P., Rusch, V. W., & Amar, D. (2007) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2007.05.053 · Cited by 218
Low-Tidal-Volume Ventilation in the Acute Respiratory Distress Syndrome
Malhotra, A. (2007) · New England Journal of Medicine · doi:10.1056/nejmct074213 · Cited by 222
Epidemiology and Outcome of Severe Sepsis and Septic Shock in Intensive Care Units in Mainland China
Zhou, J., Qian, C., Zhao, M., Yu, X., Kang, Y., Ma, X., Ai, Y., Xu, Y., Liu, D., An, Y., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0107181 · Cited by 213
“Acute respiratory distress syndrome (ARDS) were defined according to the American-European Consensus Conference criteria [19].”
Method
Extracellular histones are essential effectors of C5aR‐ and C5L2‐mediated tissue damage and inflammation in acute lung injury
Bosmann, M., Grailer, J. J., Ruemmler, R., Russkamp, N. F., Zetoune, F. S., Sarma, J. V., Standiford, T. J., & Ward, P. A. (2013) · The FASEB Journal · doi:10.1096/fj.13-236380 · Cited by 218
“In the current study, we used existing cryopreserved cell-free and anonymous bronchoalveolar lavage fluid (BALF) from mechanically ventilated patients that met criteria for ALI or ARDS by the European Respiratory Society/ American Thoracic Society consensus definition (46).”
Method
Adult Respiratory Distress Syndrome Due to Pulmonary and Extrapulmonary Causes: CT, Clinical, and Functional Correlations
Goodman, L. R., Fumagalli, R., Tagliabue, P. F., Tagliabue, M., Ferrario, M., Gattinoni, L., & Pesenti, A. M. (1999) · Radiology · doi:10.1148/radiology.213.2.r99nv42545 · Cited by 215
Transfusion Requirements in Surgical Oncology Patients
de Almeida, J. P., Vincent, J., Galas, F. R. B. G., de Almeida, E. P. M., Fukushima, J. T., Osawa, E., Bergamin, F., Park, C. L., Nakamura, R. E., Fonseca, S. M. R., et al. (2014) · Anesthesiology · doi:10.1097/aln.0000000000000511 · Cited by 215
Investigation of clinical and dosimetric factors associated with postoperative pulmonary complications in esophageal cancer patients treated with concurrent chemoradiotherapy followed by surgery
Wang, S.-L., Liao, Z. X., Vaporciyan, A. A., Tucker, S. L., Liu, H. W., Wei, X., Swisher, S. G., Ajani, J. A., Cox, J. D., & Komaki, R. U. (2005) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2005.08.002 · Cited by 213
The Epidemiology of Acute Respiratory Distress Syndrome in Patients Presenting to the Emergency Department With Severe Sepsis
Mikkelsen, M. E., Shah, C. V., Meyer, N. J., Gaieski, D. F., Lyon, S. M., Miltiades, A., Goyal, M. K., Fuchs, B. D., Bellamy, S. L., & Christie, J. D. (2013) · Shock · doi:10.1097/shk.0b013e3182a64682 · Cited by 220
“The primary outcome was the development of ARDS requiring mechanical ventilation during the first 5 hospital days, in accord with prior studies examining disease-specific association with ARDS (22, 23).”
Result
Can body mass index predict clinical outcomes for patients with acute lung injury/acute respiratory distress syndrome? A meta-analysis
Ni, Y.-N., Luo, J. F., He, Y., Wang, Y., Hu, Y., Liu, D., Liang, B., & Liang, Z.-A. (2017) · Critical Care · doi:10.1186/s13054-017-1615-3 · Cited by 225
Atelectasis and perioperative pulmonary complications in high-risk patients
Tusman, G., Böhm, S. H., Warner, D. O., & Šprung, J. (2011) · Current Opinion in Anaesthesiology · doi:10.1097/aco.0b013e32834dd1eb · Cited by 211
Kinetic and reversibility of mechanical ventilation-associated pulmonary and systemic inflammatory response in patients with acute lung injury
Stüber, F., Wrigge, H., Schroeder, S., Wetegrove, S., Zinserling, J., Hoeft, A., & Putensen, C. (2002) · Intensive Care Medicine · doi:10.1007/s00134-002-1321-7 · Cited by 211
Acute kidney injury
Kellum, J. A. (2008) · Critical Care Medicine · doi:10.1097/ccm.0b013e318168c4a4 · Cited by 211
The American-European consensus conference on ARDS, Part 2
Artigas, A., Bernard, G. R., Carlet, J. M., Dreyfuss, D., Gattinoni, L., Hudson, L. D., Lamy, M., Marini, J. J., Matthay, M. A., Pinsky, M. R., et al. (1998) · Intensive Care Medicine · doi:10.1007/s001340050585 · Cited by 209
Self-citation
Pulmonary edema after transfusion: How to differentiate transfusion-associated circulatory overload from transfusion-related acute lung injury
Gajic, O., Gropper, M. A., & Hubmayr, R. D. (2006) · Critical Care Medicine · doi:10.1097/01.ccm.0000214311.56231.23 · Cited by 210
Muscle Weakness and 5-Year Survival in Acute Respiratory Distress Syndrome Survivors*
Dinglas, V. D., Friedman, L. A., Colantuoni, E., Méndez-Téllez, P. A., Shanholtz, C. B., Ciesla, N. D., Pronovost, P. J., & Needham, D. M. (2017) · Critical Care Medicine · doi:10.1097/ccm.0000000000002208 · Cited by 211
“In this cohort study, conducted in 13 medical, surgical, and trauma ICUs at four teaching hospitals in Baltimore, MD, we prospectively screened and enrolled consecutive mechanically ventilated patients meeting the American-European Consensus Conference criteria for acute lung injury (ALI) (16) that were in effect duri…”
Influential
Prone positioning reduces mortality from acute respiratory distress syndrome in the low tidal volume era: a meta-analysis
Beitler, J. R., Shaefi, S., Montesi, S. B., Devlin, A., Loring, S. H., Talmor, D. S., & Malhotra, A. (2014) · Intensive Care Medicine · doi:10.1007/s00134-013-3194-3 · Cited by 216
“Eligible studies involved adult patients meeting the Berlin definition of ARDS [5, 27], including those previously classified as having acute lung injury (PaO2:FiO2 201–300 mmHg) under the 1994 American-European Consensus Conference definition [28].”
Method
Randomized Clinical Trial of Activated Protein C for the Treatment of Acute Lung Injury
Liu, K. D., Levitt, J. E., Zhuo, H., Kallet, R. H., Brady, S. E., Steingrub, J. S., Tidswell, M., Siegel, M. D., Soto, G. J., Peterson, M. W., et al. (2008) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200803-419oc · Cited by 206
Impact of acute hypercapnia and augmented positive end-expiratory pressure on right ventricle function in severe acute respiratory distress syndrome
Dessap, A. M., Charron, C., Devaquet, J., Aboab, J., Jardin, F., Brochard, L. J., & Vieillard‐Baron, A. (2009) · Intensive Care Medicine · doi:10.1007/s00134-009-1569-2 · Cited by 209
Prediction of Prognosis for Acute Respiratory Distress Syndrome with Thin-Section CT: Validation in 44 Cases
Ichikado, K., Suga, M., Muranaka, H., Gushima, Y., Miyakawa, H., Tsubamoto, M., Johkoh, T., Hirata, N., Yoshinaga, T., Kinoshita, Y., et al. (2006) · Radiology · doi:10.1148/radiol.2373041515 · Cited by 208
Biochemical changes after trauma and skeletal surgery of the lower extremity: Quantification of the operative burden
Pape, H., Schmidt, R. E., Rice, J., van Griensven, M., das Gupta, R., Krettek, C., & Tscherne, H. (2000) · Critical Care Medicine · doi:10.1097/00003246-200010000-00012 · Cited by 209
A comparison of observed versus estimated baseline creatinine for determination of RIFLE class in patients with acute kidney injury
Bagshaw, S. M., Uchino, S., Cruz, D., Bellomo, R., Morimatsu, H., Morgera, S., Schetz, M., Tan, I. K. S., Bouman, C. S. C., Macedo, E. M., et al. (2009) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfp159 · Cited by 209
Proteases and lung injury
Moraes, T. J., Chow, C., & Downey, G. P. (2003) · Critical Care Medicine · doi:10.1097/01.ccm.0000057842.90746.1e · Cited by 208
Management of acute lung injury and acute respiratory distress syndrome in children
Randolph, A. G. (2009) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181aee5dd · Cited by 210
A Randomized Phase II Trial of Granulocyte-Macrophage Colony-Stimulating Factor Therapy in Severe Sepsis with Respiratory Dysfunction
Presneill, J., Harris, T., Stewart, A. G., Cade, J. F., & Wilson, J. W. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2009005 · Cited by 207
Intensive Nutrition in Acute Lung Injury: A Clinical Trial (INTACT)
Braunschweig, C. A., Sheean, P. M., Peterson, S. J., Gomez Perez, S., Freels, S., Lateef, O., Gurka, D., & Fantuzzi, G. (2015) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607114528541 · Cited by 199
The Clinical Spectrum of Severe Imported Falciparum Malaria in the Intensive Care Unit: Report of 188 Cases in Adults
Bruneel, F., Hocqueloux, L., Alberti, C., Wolff, M., Chevret, S., Bédos, J.-P., Durand, R., Le Bras, J., Régnier, B., & Vachon, F. (2003) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200206-631oc · Cited by 207
Citation classics in critical care medicine
Baltussen, A., & Kindler, C. H. (2004) · Intensive Care Medicine · doi:10.1007/s00134-004-2195-7 · Cited by 205
A Randomized Clinical Trial of Hydroxymethylglutaryl– Coenzyme A Reductase Inhibition for Acute Lung Injury (The HARP Study)
Craig, T. R., Duffy, M. J., Shyamsundar, M., McDowell, C., O’Kane, C. M., Elborn, J. S., & McAuley, D. F. (2010) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201003-0423oc · Cited by 209
International comparisons of intensive care
Prin, M., & Wunsch, H. (2012) · Current Opinion in Critical Care · doi:10.1097/mcc.0b013e32835914d5 · Cited by 212
Acute lung injury in patients with subarachnoid hemorrhage: Incidence, risk factors, and outcome
Kahn, J. M., Caldwell, E., Deem, S. A., Newell, D. W., Heckbert, S. R., & Rubenfeld, G. D. (2005) · Critical Care Medicine · doi:10.1097/01.ccm.0000194540.44020.8e · Cited by 205
Acute lung injury and ARDS in acute pancreatitis: Mechanisms and potential intervention
Zhou, M. (2010) · World Journal of Gastroenterology · doi:10.3748/wjg.v16.i17.2094 · Cited by 207
Early isovolaemic haemofiltration in oliguric patients with septic shock
Piccinni, P., Dan, M., Barbacini, S., Carraro, R., Lieta, E., Marafon, S., Zamperetti, N., Brendolan, A., D’Intini, V., Tetta, C., et al. (2005) · Intensive Care Medicine · doi:10.1007/s00134-005-2815-x · Cited by 208
Current incidence and outcome of the acute respiratory distress syndrome
Villar, J., Blanco, J., & Kacmarek, R. M. (2015) · Current Opinion in Critical Care · doi:10.1097/mcc.0000000000000266 · Cited by 207
“In 1994, an American–European Consensus Conference (AECC) defined ARDS as follows [2]: acute and sudden onset of severe respiratory distress, bilateral infiltrates on frontal chest radiograph, the absence of left atrial hypertension (a pulmonary capillary wedge pressure <18 mmHg) or no clinical signs of”
Background
Hemoglobin conformation couples erythrocyte S -nitrosothiol content to O 2 gradients
Doctor, A., Platt, R., Sheram, M. L., Eischeid, A. C., McMahon, T., Maxey, T., Doherty, J., Axelrod, M. J., Kline, J. M., Gurka, M. J., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407490102 · Cited by 206
APOε4 is associated with enhanced in vivo innate immune responses in human subjects
Gale, S. C., Gao, L., Mikacenic, C., Coyle, S. M., Rafaels, N., Murray Dudenkov, T., Madenspacher, J. H., Draper, D. W., Ge, W., Aloor, J. J., et al. (2014) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2014.01.032 · Cited by 202
An overview of pulmonary surfactant in the neonate: Genetics, metabolism, and the role of surfactant in health and disease
Nkadi, P. O., Merritt, T. A., & Pillers, D. M. (2009) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2009.01.015 · Cited by 206
Noninvasive versus invasive ventilation for acute respiratory failure in patients with hematologic malignancies: A 5-year multicenter observational survey*
Gristina, G. R., Antonelli, M. M., Conti, G., Ciarlone, A., Rogante, S., Rossi, C., & Bertolini, G. (2011) · Critical Care Medicine · doi:10.1097/ccm.0b013e3182227a27 · Cited by 205
Epidemiology of Acute Lung Injury and ARDS
Hudson, L. D., & Steinberg, K. P. (1999) · CHEST Journal · doi:10.1378/chest.116.suppl_1.74s-a · Cited by 206
Self-citation
Mitochondrial Membrane Potential and Apoptosis Peripheral Blood Monocytes in Severe Human Sepsis
Adrie, C., Bachelet, M., Vayssier‐Taussat, M., Russo‐Marie, F., Bouchaert, I., Adib‐Conquy, M., Cavaillon, J., Pinsky, M. R., Dhainaut, J.-F., & Polla, B. S. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.164.3.2009088 · Cited by 203
Risk factors and outcome of transfusion-related acute lung injury in the critically ill: A nested case–control study*
Vlaar, A. P. J., Binnekade, J. M., Prins, D. J., Stein, D. V., Hofstra, J. J., Schultz, M. J., & Juffermans, N. P. (2010) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181cc4d4b · Cited by 205
Nonlinear Imputation of Pao2/Fio2 From Spo2/Fio2 Among Patients With Acute Respiratory Distress Syndrome
Brown, S. M., Grissom, C. K., Moss, M., Rice, T. W., Schoenfeld, D., Hou, P. C., Thompson, B., & Brower, R. G. (2016) · CHEST Journal · doi:10.1016/j.chest.2016.01.003 · Cited by 204
“The ratio of partial pressure of arterial oxygen (PaO2) to the fraction of inspired oxygen (FIO2) (PAO2/FIO2 ratio) measures the severity of hypoxemia in patients with ARDS.”
MethodInfluential
Acute lung injury in children: Therapeutic practice and feasibility of international clinical trials*
Santschi, M., Jouvet, P. A., Leclerc, F., Gauvin, F., Newth, C. J. L., Carroll, C. L., Flori, H. R., Tasker, R. C., Rimensberger, P. C., & Randolph, A. G. (2010) · Pediatric Critical Care Medicine · doi:10.1097/pcc.0b013e3181d904c0 · Cited by 205
Psychiatric symptoms after acute respiratory distress syndrome: a 5-year longitudinal study
Bienvenu, O. J., Friedman, L. A., Colantuoni, E., Dinglas, V. D., Sepúlveda, K. A., Méndez-Téllez, P. A., Shanholz, C., Pronovost, P. J., & Needham, D. M. (2017) · Intensive Care Medicine · doi:10.1007/s00134-017-5009-4 · Cited by 212
“Study population In the Improving Care of Acute lung injury Patients (ICAP) prospective longitudinal cohort study, we enrolled consecutive mechanically ventilated patients with acute lung injury (ALI), as defined by AmericanEuropean Consensus criteria [8] in effect at the time of study recruitment (2004–2007) (Clinica…”
Method
Pulmonary coagulopathy as a new target in therapeutic studies of acute lung injury or pneumonia—A review
Schultz, M. J., Haitsma, J. J., Zhang, H., & Slutsky, A. S. (2006) · Critical Care Medicine · doi:10.1097/01.ccm.0000201882.23917.b8 · Cited by 203
Fluid balance in critically ill children with acute lung injury*
Valentine, S. L., Sapru, A., Higgerson, R. A., Spinella, P. C., Flori, H. R., Graham, D. A., Brett, M. S., Convery, M., Christie, L. M., Karamessinis, L. R., et al. (2012) · Critical Care Medicine · doi:10.1097/ccm.0b013e31825bc54d · Cited by 199
Elevated plasma levels of soluble TNF receptors are associated with morbidity and mortality in patients with acute lung injury
Parsons, P. E., Matthay, M. A., Ware, L. B., & Eisner, M. D. (2004) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00302.2004 · Cited by 204
Acute Lung Injury in Patients with Severe Brain Injury: A Double Hit Model
Mascia, L. (2009) · Neurocritical Care · doi:10.1007/s12028-009-9242-8 · Cited by 201
Prevalence, etiologies and outcome of the acute respiratory distress syndrome among hypoxemic ventilated patients
Roupie, É., Lepage, É., Wysocki, M., Fagon, J.-Y., Chastre, J. E., Dreyfuss, D., Mentec, H., Carlet, J. M., Brun‐Buisson, C., Lemaire, F., et al. (1999) · Intensive Care Medicine · doi:10.1007/s001340050983 · Cited by 201
Self-citation
Timing of Orthopaedic Surgery in Multiple Trauma Patients
Vallier, H. A., Wang, X., Moore, T. A., Wilber, J. H., & Como, J. J. (2013) · Journal of Orthopaedic Trauma · doi:10.1097/bot.0b013e31829efda1 · Cited by 202
“4 consecutive days with diffuse infiltrates on chest radiographs, in the absence of pneumonia.(51) Pneumonia was defined by plain chest radiograph with a new pulmonary infiltrate in the presence of purulent sputum, temperature .”
Background
Acute Lung Injury in Leptospirosis: Clinical and Laboratory Features, Outcome, and Factors Associated with Mortality
Marotto, P. C. F., Murta‐Nascimento, C., Eluf‐Neto, J., Marotto, M. S., Andrade, L., Sztajnbok, J., & Seguro, A. C. (1999) · Clinical Infectious Diseases · doi:10.1086/313501 · Cited by 201
Prognostic Value of the Pulmonary Dead-Space Fraction During the Early and Intermediate Phases of Acute Respiratory Distress Syndrome
Raurich, J. M., Vilar, M., Colomar, A., Ibáñez, J., Ayestarán, I., Pérez‐Bárcena, J., & Llompart‐Pou, J. A. (2010) · Respiratory Care · doi:10.4187/respcare.10550282 · Cited by 199
Extravascular lung water in patients with severe sepsis: a prospective cohort study
Martin, G. S., Eaton, S., Mealer, M. L., & Moss, M. (2005) · Critical Care · doi:10.1186/cc3025 · Cited by 199
A universal definition of ARDS: the PaO2/FiO2 ratio under a standard ventilatory setting—a prospective, multicenter validation study
Villar, J., Pérez‐Méndez, L., Blanco, J., Añón, J. M., Blanch, L. L., Belda, J., Santos-Bouza, A., Fernández, R. L., Kacmarek, R. M., & Spanish Initiative for Epidemiology, S. (2013) · Intensive Care Medicine · doi:10.1007/s00134-012-2803-x · Cited by 208
Effects of Delayed Wound Excision and Grafting in Severely Burned Children
Wu, X. (2002) · Archives of Surgery · doi:10.1001/archsurg.137.9.1049 · Cited by 200
Clinical and mechanistic drivers of acute traumatic coagulopathy
Cohen, M. J. M., Kutcher, M., Redick, B. J., Nelson, M. F., Call, M. S., Knudson, M. M., Schreiber, M. A., Bulger, E. M., Muskat, P. C., Alarcon, L. H., et al. (2013) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/ta.0b013e31828fa43d · Cited by 200
Prospective, Randomized, Controlled Pilot Study of Partial Liquid Ventilation in Adult Acute Respiratory Distress Syndrome
Hirschl, R. B., Croce, M. A., Gore, D. C., Wiedemann, H. P., Davis, K., Zwischenberger, J. B., & Bartlett, R. H. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.165.6.2003052 · Cited by 200
Acute Respiratory Distress Syndrome in Blunt Trauma: Identification of Independent Risk Factors
Miller, P. R., Croce, M. A., Kilgo, P. D., Scott, J., & Fabian, T. C. (2002) · The American Surgeon · doi:10.1177/000313480206801002 · Cited by 195
Thirty years of clinical trials in acute respiratory distress syndrome
McIntyre, R. C., Pulido, E. J., Bensard, D. D., Shames, B. D., & Abraham, E. H. (2000) · Critical Care Medicine · doi:10.1097/00003246-200009000-00034 · Cited by 194
Acute lung injury following blood transfusion: Expanding the definition
Marik, P. E., & Corwin, H. L. (2008) · Critical Care Medicine · doi:10.1097/ccm.0b013e31818c3801 · Cited by 197
Pharmacotherapy of Acute Lung Injury and the Acute Respiratory Distress Syndrome
Cepkova, M., & Matthay, M. A. (2006) · Journal of Intensive Care Medicine · doi:10.1177/0885066606287045 · Cited by 198
Recovery from Dysphagia Symptoms after Oral Endotracheal Intubation in Acute Respiratory Distress Syndrome Survivors. A 5-Year Longitudinal Study
Brodsky, M. B., Huang, M., Shanholtz, C. B., Méndez-Téllez, P. A., Palmer, J. B., Colantuoni, E., & Needham, D. M. (2017) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201606-455oc · Cited by 198
“The present analysis is part of a prospective, multi-site cohort study (Improving Care of ALI Patients (ICAP) evaluating consecutively recruited mechanically ventilated patients with acute lung injury defined using the American-European Consensus Conference criteria (18) in effect at”
Method
Pulmonary fibrosis and lung cancer: risk and benefit analysis of pulmonary resection
Kumar, P. M., Goldstraw, P. G., Yamada, K., Nicholson, A. G., Wells, A. U., Hansell, D. M., du Bois, R. M., & Ladas, G. (2003) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/s0022-5223(03)00028-x · Cited by 197
Race and gender differences in acute respiratory distress syndrome deaths in the United States: An analysis of multiple-cause mortality data (1979–1996)*
Moss, M. M., & Mannino, D. M. (2002) · Critical Care Medicine · doi:10.1097/00003246-200208000-00001 · Cited by 199
High-Frequency Ventilation for Acute Lung Injury and ARDS
Krishnan, J. A., & Brower, R. G. (2000) · CHEST Journal · doi:10.1378/chest.118.3.795 · Cited by 195

Authors: Bernard, G. R., Artigas, A., Brigham, K. L., Carlet, J., Falke, K., Hudson, L., Lamy, M., Legall, J. R., Morris, A., & Spragg, R.
Affiliations: Vanderbilt University (US)
Vanderbilt University, Nashville, Tennessee
ORCID: Bernard, G R
Artigas, A
Carlet, J
Lamy, M
Morris, A
Venue: American journal of respiratory and critical care medicine
Publisher: Oxford University Press (OUP)
Published: 1994-03-01
Volume: 149
Issue: 3
Pages: 818-824
ISSN: 1073-449X (ISSN-L)
1535-4970
DOI: 10.1164/ajrccm.149.3.7509706
OpenAlex: W2161328469
Cited by: 6,746
References: 20
Citations by year: 2026: 54 · 2025: 112 · 2024: 107 · 2023: 119 · 2022: 126 · 2021: 164 · 2020: 158 · 2019: 184 · 2018: 156 · 2017: 192 · 2016: 238 · 2015: 241 · 2014: 289 · 2013: 341 · 2012: 364
FWCI: 80.47
Type: journal article
Language: en
Open access: closed
Licence: academic.oup.com/pages/standard-publication-reuse-rights (vor)
Locations: American Journal of Respiratory and Critical Care Medicine (publishedVersion)
PubMed (publishedVersion)
D-Scholarship@Pitt (University of Pittsburgh) (acceptedVersion)
Funders: National Institutes of Health (5r01hl043167-05, 5p50hl019153-22)
National Heart, Lung, and Blood Institute (NHLBI HL19153, NHLBI HL43167)
Topics: Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Neonatal Respiratory Health Research
Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Sepsis Diagnosis and Treatment
Keywords: acute respiratory distress syndrome, ARDS definition, ARDS pathophysiology, ARDS incidence, ARDS mortality, clinical trial coordination
MeSH terms: Americas, Clinical Protocols, Clinical Trials as Topic, Europe, Humans, Oxygen Inhalation Therapy, Prognosis, Radiography, Respiratory Distress Syndrome, Risk Factors, Incidence, Prevalence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The American-European Consensus Conference On Ards. Definitions, Mechanisms, Relevant Outcomes, And Clinical Trial Coordination

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks