The DOI matches its Crossref record; 67 of the 67 references it cites were found in a registry or an index.
Oxidative Stress in Pulmonary Fibrosis: A Possible Role for Redox Modulatory Therapy
Open accessAbstract
Idiopathic ulmonary fibrosis (histopathology of usual interstitial pneumonia) is a progressive lung disease of unknown etiology. No treatment has been shown to improve the prognosis of the patients with this disease. Recent evidence, including the observations that the patients with idiopathic pulmonary fibrosis have higher levels of oxidant stress than control patients, and a recent multicenter European study examining the effect of the antioxidant N-acetylcysteine on the progression of idiopathic pulmonary fibrosis suggest that the cellular redox state may play a significant role in the progression of this disease. These complex mechanisms include activation of growth factors as well as regulation of matrix metalloproteinases and protease inhibitors. Potential future approaches for the therapy of interstitial pulmonary fibrosis may involve synthetic agents able to modulate cellular redox state. Investigation into therapeutic approaches to inhibit oxidant-mediated reactions in the initiation and progression of pulmonary fibrosis may provide hope for the future treatment of this disease.
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Cites
Myofibroblasts and mechano-regulation of connective tissue remodelling
Tomasek, J. J., Gabbiani, G., Hinz, B., Chaponnier, C., & Brown, R. A. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm809 · Cited by 4,290
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Matrix metalloproteinases as modulators of inflammation and innate immunity
Parks, W. C., Wilson, C. L., & López-Boado, Y. S. (2004) · Nature Reviews Immunology · doi:10.1038/nri1418 · Cited by 1,929
Transforming growth factor type beta induces monocyte chemotaxis and growth factor production.
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Wang, E.-S., Yao, H.-B., Chen, Y.-H., Wang, G., Gao, W.-W., Sun, Y.-R., Guo, J.-G., Hu, J.-W., Jiang, C.-C., & Hu, J. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350082 · Cited by 1,176
Gross, T. J., & Hunninghake, G. W. (2001) · New England Journal of Medicine · doi:10.1056/nejmra003200 · Cited by 962
Cellular glutathione and thiols metabolism
Dickinson, D. A., & Forman, H. J. (2002) · Biochemical Pharmacology · doi:10.1016/s0006-2952(02)01172-3 · Cited by 851
Exhaled Markers of Pulmonary Disease
KHARITONOV, S. A., & BARNES, P. J. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.163.7.2009041 · Cited by 844
Mechanisms of Pulmonary Fibrosis
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A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis
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Cited by
Oxidative stress, inflammation, and cancer: How are they linked?
Reuter, S., Gupta, S. C., Chaturvedi, M. M., & Aggarwal, B. B. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.09.006 · Cited by 5,441
King, T. E., Pardo, A., & Selman, M. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60052-4 · Cited by 2,194
Reactive oxygen and nitrogen species as signaling molecules regulating neutrophil function
Fialkow, L., Wang, Y., & Downey, G. P. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2006.09.030 · Cited by 708
Reversal of persistent fibrosis in aging by targeting Nox4-Nrf2 redox imbalance
Hecker, L., Logsdon, N. J., Kurundkar, D., Kurundkar, A., Bernard, K., Hock, T., Meldrum, E., Sanders, Y. Y., & Thannickal, V. J. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3008182 · Cited by 686
Redox Control of the Cell Cycle in Health and Disease
Sarsour, E. H., Kumar, M. G., Chaudhuri, L., Kalen, A. L., & Goswami, P. C. (2009) · Antioxidants & Redox Signaling · doi:10.1089/ars.2009.2513 · Cited by 381
Metadata
- Authors
- Kinnula, V. L., Fattman, C. L., Tan, R. J., & Oury, T. D.
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-08-15
- Volume
- 172
- Issue
- 4
- Pages
- 417-422
- ISSN
- 1073-449X (ISSN-L)
- 1535-4970
- OpenAlex
- W2014187911
- Cited by
- 437
- References
- 67
- FWCI
- 16.03
- Type
- journal article
- Language
- en
- Open access
- green
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- Kinnula, V. L., Fattman, C. L., Tan, R. J., & Oury, T. D. (2005). Oxidative Stress in Pulmonary Fibrosis: A Possible Role for Redox Modulatory Therapy. American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/rccm.200501-017pp
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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