The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
Innate Immune Recognition in Infectious and Noninfectious Diseases of the Lung
Abstract
Diseases of the respiratory tract are among the leading causes of death in the world population. Increasing evidence points to a key role of the innate immune system with its pattern recognition receptors (PRRs) in both infectious and noninfectious lung diseases, which include pneumonia, chronic obstructive pulmonary disease, acute lung injury, pneumoconioses, and asthma. PRRs are capable of sensing different microbes as well as endogenous molecules that are released after cell damage. This PRR engagement is the prerequisite for the initiation of immune responses to infections and tissue injuries which can be beneficial or detrimental to the host. PRRs include the Toll-like receptors, NOD-like receptors, RIG-I-like receptors, and cytosolic DNA sensors. The PRRs and their signaling pathways represent promising targets for prophylactic and therapeutic interventions in various lung diseases.
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Cites
A Toll-like receptor recognizes bacterial DNA
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Gout-associated uric acid crystals activate the NALP3 inflammasome
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Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
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STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
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The acute respiratory distress syndrome
Matthay, M. A., Ware, L. B., & Zimmerman, G. A. (2012) · Journal of Clinical Investigation · doi:10.1172/jci60331 · Cited by 1,706
Pathogenesis of Acute Respiratory Distress Syndrome
Huppert, L., Matthay, M., & Ware, L. (2019) · Seminars in Respiratory and Critical Care Medicine · doi:10.1055/s-0039-1683996 · Cited by 459
Amino-Functionalized Polystyrene Nanoparticles Activate the NLRP3 Inflammasome in Human Macrophages
Lunov, O., Syrovets, T., Loos, C., Nienhaus, G. U., Mailänder, V., Landfester, K., Rouis, M., & Simmet, T. (2011) · ACS Nano · doi:10.1021/nn203596e · Cited by 262
Achouiti, A., Vogl, T., Urban, C. F., Röhm, M., Hommes, T. J., van Zoelen, M. A. D., Florquin, S., Roth, J., van 't Veer, C., de Vos, A. F., et al. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1002987 · Cited by 135
Wang, L., Tang, Y., Liu, S., Mao, S., Ling, Y., Liu, D., He, X., & Wang, X. (2013) · PLoS ONE · doi:10.1371/journal.pone.0065675 · Cited by 97
Metadata
- Authors
- Opitz, B., van Laak, V., Eitel, J., & Suttorp, N.
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-06-15
- Volume
- 181
- Issue
- 12
- Pages
- 1294-1309
- ISSN
- 1073-449X (ISSN-L)
- 1535-4970
- OpenAlex
- W2150086428
- Cited by
- 274
- References
- 34
- FWCI
- 7.38
- Type
- journal article
- Language
- en
- Open access
- closed
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- Opitz, B., van Laak, V., Eitel, J., & Suttorp, N. (2010). Innate Immune Recognition in Infectious and Noninfectious Diseases of the Lung. American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/rccm.200909-1427so
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
