Piezo1 incorporates mechanical force signals into the genetic program that governs lymphatic valve development and maintenance

Calcium's Role in Mechanotransduction during Muscle Development

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Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

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Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

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Piezo proteins are pore-forming subunits of mechanically activated channels

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Piezo1, a mechanically activated ion channel, is required for vascular development in mice

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VE-Cadherin and Endothelial Adherens Junctions: Active Guardians of Vascular Integrity

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Chemical activation of the mechanotransduction channel Piezo1

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Piezo1 links mechanical forces to red blood cell volume

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The Lymphatic Vasculature in the 21st Century: Novel Functional Roles in Homeostasis and Disease

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Discoveries in structure and physiology of mechanically activated ion channels

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The mechanosensitive Piezo1 channel is required for bone formation

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Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin

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Stimulation of Piezo1 by mechanical signals promotes bone anabolism

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Mechanisms of mechanotransduction and physiological roles of PIEZO channels

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The mechanosensitive Piezo1 channel mediates heart mechano-chemo transduction

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Vascular mechanotransduction

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Force Sensing by Piezo Channels in Cardiovascular Health and Disease

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Roles of mechanosensitive channel Piezo1/2 proteins in skeleton and other tissues

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Piezo Ion Channels in Cardiovascular Mechanobiology

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The Importance of Mechanical Forces for in vitro Endothelial Cell Biology

Gordon, E. J., Schimmel, L., & Frye, M. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00684 · Cited by 177

Levering Mechanically Activated Piezo Channels for Potential Pharmacological Intervention

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Vascular endothelial cell specification in health and disease

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Advances in Lymphedema

Rockson, S. G. (2021) · Circulation Research · doi:10.1161/circresaha.121.318307 · Cited by 130

Magnetic Aggregation‐Induced Bone‐Targeting Nanocarrier with Effects of Piezo1 Activation and Osteogenic–Angiogenic Coupling for Osteoporotic Bone Repair

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Dendritic cell Piezo1 directs the differentiation of TH1 and Treg cells in cancer

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Primary lymphoedema

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Piezo1-Regulated Mechanotransduction Controls Flow-Activated Lymphatic Expansion

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Meningeal lymphatic drainage: novel insights into central nervous system disease

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PIEZO channels and newcomers in the mammalian mechanosensitive ion channel family

Delmas, P., Parpaite, T., & Coste, B. (2022) · Neuron · doi:10.1016/j.neuron.2022.07.001 · Cited by 96

Development and aging of the lymphatic vascular system

González-Loyola, A., & Petrova, T. V. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2020.12.005 · Cited by 89

PIEZO Ion Channels in Cardiovascular Functions and Diseases

Coste, B., & Delmas, P. (2024) · Circulation Research · doi:10.1161/circresaha.123.322798 · Cited by 93

Emerging Piezo1 signaling in inflammation and atherosclerosis; a potential therapeutic target

Shinge, S. A. U., Zhang, D., Din, A. U., Yu, F., & Nie, Y. (2022) · International Journal of Biological Sciences · doi:10.7150/ijbs.63819 · Cited by 85

The Role of Inflammation in Lymphedema: A Narrative Review of Pathogenesis and Opportunities for Therapeutic Intervention

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Ileitis-associated tertiary lymphoid organs arise at lymphatic valves and impede mesenteric lymph flow in response to tumor necrosis factor

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Beyond PROX1: transcriptional, epigenetic, and noncoding RNA regulation of lymphatic identity and function

Ducoli, L., & Detmar, M. J. (2021) · Developmental Cell · doi:10.1016/j.devcel.2021.01.018 · Cited by 76

Biomechanical control of lymphatic vessel physiology and functions

Angeli, V., & Lim, H. Y. (2023) · Cellular and Molecular Immunology · doi:10.1038/s41423-023-01042-9 · Cited by 75

Piezo1 agonist restores meningeal lymphatic vessels, drainage, and brain-CSF perfusion in craniosynostosis and aged mice

Matrongolo, M. J., Ang, P. S., Wu, J., Jain, A., Thackray, J. K., Reddy, A., Sung, C.-C., Barbet, G., Hong, Y., & Tischfield, M. A. (2023) · Journal of Clinical Investigation · doi:10.1172/jci171468 · Cited by 72

Matrix stiffness induces Drp1-mediated mitochondrial fission through Piezo1 mechanotransduction in human intervertebral disc degeneration

Ke, W., Wang, B., Liao, Z., Song, Y., Li, G., Ma, L., Wang, K., Li, S., Hua, W., & Cao, Y. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04590-w · Cited by 66

Adenosine Triphosphate Release and P2 Receptor Signaling in Piezo1 Channel-Dependent Mechanoregulation

Wei, L., Mousawi, F., Li, D., Roger, S., Li, J., Yang, X., & Jiang, L. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.01304 · Cited by 68

Piezo1 regulates meningeal lymphatic vessel drainage and alleviates excessive CSF accumulation

Choi, D., Park, E.-K., Choi, J., Lu, R., Yu, J. S., Kim, C., Zhao, L., Yu, J., Nakashima, B., Lee, S., et al. (2024) · Nature Neuroscience · doi:10.1038/s41593-024-01604-8 · Cited by 66

Lymphatic Vessels and Their Surroundings: How Local Physical Factors Affect Lymph Flow

Solari, E., Marcozzi, C., Negrini, D., & Moriondo, A. (2020) · Biology · doi:10.3390/biology9120463 · Cited by 64

Piezo channels in the urinary system

Li, X., Hu, J., Zhao, X.-D., Li, J., & Chen, Y. (2022) · Experimental & Molecular Medicine · doi:10.1038/s12276-022-00777-1 · Cited by 67

S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress–dependent VEGF-C signaling

Geng, X., Yanagida, K., Akwii, R. G., Choi, D., Chen, L., Ho, Y., Cha, B., Mahamud, M. R., de Ruiz, K. B., Ichise, H., et al. (2020) · JCI Insight · doi:10.1172/jci.insight.137652 · Cited by 61

Yoda1’s energetic footprint on Piezo1 channels and its modulation by voltage and temperature

Wijerathne, T. D., Özkan, A. D., & Lacroix, J. J. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2202269119 · Cited by 58

Pharmacology of PIEZO1 channels

Kinsella, J. A., Debant, M., Parsonage, G., Morley, L. C., Bajarwan, M., Revill, C., Foster, R., & Beech, D. J. (2024) · British Journal of Pharmacology · doi:10.1111/bph.17351 · Cited by 60

Development and physiological functions of the lymphatic system: insights from human genetic studies of primary lymphedema

Martin‐Almedina, S., Mortimer, P. S., & Østergaard, P. (2021) · Physiological Reviews · doi:10.1152/physrev.00006.2020 · Cited by 62

Modeling of full-length Piezo1 suggests importance of the proximal N-terminus for dome structure

Chong, J., Vecchis, D. D., Hyman, A. J., Povstyan, O. V., Ludlow, M. J., Shi, J., Beech, D. J., & Kalli, A. C. (2021) · Biophysical Journal · doi:10.1016/j.bpj.2021.02.003 · Cited by 59

Recent advances in the pathophysiology of PIEZO1 ‐related hereditary xerocytosis

Jankovsky, N., Caulier, A., Demagny, J., Guitton, C., Djordjevic, S., Lebon, D., Ouled‐Haddou, H., Picard, V., & Garçon, L. (2021) · American Journal of Hematology · doi:10.1002/ajh.26192 · Cited by 55

Piezo1 promoted hepatocellular carcinoma progression and EMT through activating TGF-β signaling by recruiting Rab5c

Li, Y.-M., Xu, C., Sun, B., Zhong, F.-J., Cao, M., & Yang, L.-Y. (2022) · Cancer Cell International · doi:10.1186/s12935-022-02574-2 · Cited by 52

Mechanotransduction in cardiovascular morphogenesis and tissue engineering

Duchemin, A., Vignes, H., Vermot, J., & Chow, R. (2019) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2019.08.002 · Cited by 55

YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling

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GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126

Mahamud, M. R., Geng, X., Ho, Y., Cha, B., Kim, Y., Ma, J., Chen, L., Myers, G., Camper, S. A., Mustacich, D. J., et al. (2019) · Development · doi:10.1242/dev.184218 · Cited by 49

Structural and thermodynamic framework for PIEZO1 modulation by small molecules

Jiang, W., Wijerathne, T. D., Zhang, H., Lin, Y.-C., Jo, S., Im, W., Lacroix, J. J., & Luo, Y. L. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2310933120 · Cited by 44

Transport and Immune Functions of the Lymphatic System.

Davis, M. J., Zawieja, S. D., & King, P. D. (2025) · Annual Review of Physiology · doi:10.1146/annurev-physiol-022724-104908 · Cited by 42

Lymphatic Valves and Lymph Flow in Cancer-Related Lymphedema

Iyer, D., Jannaway, M., Yang, Y., & Scallan, J. P. (2020) · Cancers · doi:10.3390/cancers12082297 · Cited by 43

Skull progenitor cell-driven meningeal lymphatic restoration improves neurocognitive functions in craniosynostosis

Ma, L., Chang, Q., Pei, F., Liu, M., Zhang, W., Hong, Y., Chai, Y., & Chen, J. (2023) · Cell stem cell · doi:10.1016/j.stem.2023.09.012 · Cited by 41

The role of mechanically sensitive ion channel Piezo1 in bone remodeling

Du, Y., Xu, B., Li, Q., Peng, C., & Yang, K. (2024) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2024.1342149 · Cited by 40

PIEZO1 targeting in macrophages boosts phagocytic activity and foam cell apoptosis in atherosclerosis

Pourteymour, S., Fan, J., Majhi, R. K., Guo, S., Sun, X., Huang, Z., Liu, Y., Winter, H., Bäcklund, A., Skenteris, N.-T., et al. (2024) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-024-05372-3 · Cited by 39

Emerging role of Piezo ion channels in cardiovascular development

Shah, V., Patel, S., & Shah, J. (2021) · Developmental Dynamics · doi:10.1002/dvdy.401 · Cited by 39

Role of lymphatic endothelial cells in the tumor microenvironment—a narrative review of recent advances

He, M., He, Q., Cai, X., Chen, Z., Lao, S., Deng, H., Liu, X., Zheng, Y., Liu, X., Liu, J., et al. (2021) · Translational Lung Cancer Research · doi:10.21037/tlcr-21-40 · Cited by 37

Lymph Flow Induces the Postnatal Formation of Mature and Functional Meningeal Lymphatic Vessels

Bálint, L., Ocskay, Z., Deák, B. A., Aradi, P., & Jakus, Z. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2019.03043 · Cited by 34

The mechanosensory channel PIEZO1 functions upstream of angiopoietin/TIE/FOXO1 signaling in lymphatic development

Du, J., Liu, P., Zhou, Y., Misener, S., Sharma, I., Leeaw, P., Thomson, B. R., Jin, J., & Quaggin, S. E. (2024) · Journal of Clinical Investigation · doi:10.1172/jci176577 · Cited by 29

Biomechanics in bone regeneration and mechanobiology in osteoblasts: Fundamental concepts and recent progress

Cai, W., Huo, Y., Liu, Y., Su, Y., Guo, H., Wang, L., Li, B., & Liang, T. (2025) · EngMedicine · doi:10.1016/j.engmed.2025.100057 · Cited by 31

A New Hope in Spinal Degenerative Diseases: Piezo1

Zhu, D., Zhang, G., Guo, X., Wang, Y., Liu, M., & Kang, X. (2021) · BioMed Research International · doi:10.1155/2021/6645193 · Cited by 29

The Migration and the Fate of Dental Pulp Stem Cells

Lampiasi, N. (2023) · Biology · doi:10.3390/biology12050742 · Cited by 28

PIEZO channels as multimodal mechanotransducers

Lacroix, J. J., & Wijerathne, T. D. (2025) · Biochemical Society Transactions · doi:10.1042/bst20240419 · Cited by 28

The role of mechanosensitive Piezo1 channel in diseases

Song, S., Zhang, H., Wang, X., Chen, W., Cao, W., Zhang, Z., & Shi, C. (2022) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2022.04.006 · Cited by 27

Mechanosensation and Mechanotransduction by Lymphatic Endothelial Cells Act as Important Regulators of Lymphatic Development and Function

Bálint, L., & Jakus, Z. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22083955 · Cited by 26

Piezo protein determines stem cell fate by transmitting mechanical signals

Qiu, X., Deng, Z., Wang, M., Feng, Y., Bi, L., & Li, L. (2022) · Human Cell · doi:10.1007/s13577-022-00853-8 · Cited by 26

Pacemaking in the lymphatic system

Davis, M. J., & Zawieja, S. D. (2024) · The Journal of Physiology · doi:10.1113/jp284752 · Cited by 26

A 3D Human Lymphatic Vessel-on-Chip Reveals the Roles of Interstitial Flow and VEGF-A/C for Lymphatic Sprouting and Discontinuous Junction Formation

Ilan, I. S., Yslas, A. R., Peng, Y., Lu, R., & Lee, E. (2023) · Cellular and Molecular Bioengineering · doi:10.1007/s12195-023-00780-0 · Cited by 25

Role of mechanosensitive ion channel Piezo1 in tension-side orthodontic alveolar bone remodeling in rats

Du, Y., & Yang, K. (2023) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2023.105798 · Cited by 25

Biochemical and mechanical signals in the lymphatic vasculature

Geng, X., Ho, Y., & Srinivasan, R. S. (2021) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-021-03886-8 · Cited by 25

FOXO1 represses lymphatic valve formation and maintenance via PRDM1

Niimi, K., Nakae, J., Inagaki, S., & Furuyama, T. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.110048 · Cited by 22

Lymphatic Vascular PermeabilityPreprint

Scallan, J. P., & Jannaway, M. (2022) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a041274 · Cited by 22

Deformability of Heterogeneous Red Blood Cells in Aging and Related Pathologies

Prudinnik, D. S., Kussanova, A., Vorobjev, I. A., Tikhonov, A., Ataullakhanov, F. I., & Barteneva, N. S. (2024) · Aging and Disease · doi:10.14336/ad.2024.0526 · Cited by 21

A two-step clockwork mechanism opens a proteo-lipidic pore in PIEZO2

Li, S., Wijerathne, T. D., Bhatt, A., Jiang, W., Lacroix, J. J., Han, W., & Luo, Y. (2026) · Nature Chemical Biology · doi:10.1038/s41589-026-02147-8 · Cited by 21

In Vivo Dynamic and Static Analysis of Lymphatic Dysfunction in Lymphedema Using Near-Infrared Fluorescence Indocyanine Green Lymphangiography

Cheon, H., Lee, S., Kim, S. A., Kim, B., Suh, H. P., & Jeon, J. Y. (2023) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.123.319188 · Cited by 20

Change of the Lymphatic Diameter in Different Body Positions

Hara, H., & Mihara, M. (2020) · Lymphatic Research and Biology · doi:10.1089/lrb.2020.0081 · Cited by 20

When form meets function: the cells and signals that shape the lymphatic vasculature during development

François, M., Oszmiana, A., & Harvey, N. L. (2021) · Development · doi:10.1242/dev.167098 · Cited by 19

Force-induced motions of the PIEZO1 blade probed with fluorimetry

Özkan, A. D., Wijerathne, T. D., Gettas, T., & Lacroix, J. J. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112837 · Cited by 19

Mutations in EPHB4 cause human venous valve aplasia

Lyons, O., Walker, J., Seet, C., Ikram, M., Kuchta, A., Arnold, A. J., Hernández-Vásquez, M. N., Frye, M., Vizcay‐Barrena, G., Fleck, R. A., et al. (2021) · JCI Insight · doi:10.1172/jci.insight.140952 · Cited by 19

HIF-1α promotes cellular growth in lymphatic endothelial cells exposed to chronically elevated pulmonary lymph flow

Boehme, J. B., Morris, C. J., Chiacchia, S., Gong, W., Wu, K. Y., Kameny, R. J., Raff, G. W., Fineman, J. R., Maltepe, E., & Datar, S. A. (2021) · Scientific Reports · doi:10.1038/s41598-020-80882-1 · Cited by 18

A Piez-o the jigsaw: the Piezo1 channel in skin biology

Eid, E. S., & Kurban, M. (2022) · Clinical and Experimental Dermatology · doi:10.1111/ced.15138 · Cited by 18

YAP1/Piezo1 involve in the dynamic changes of lymphatic vessels in UVR-induced photoaging progress to squamous cell carcinoma

Yang, Y., Zhou, C., Chen, Q., Shen, S., Li, J., Wang, X., & Wang, P. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04458-z · Cited by 17

S1PR1 regulates lymphatic valve development and tertiary lymphoid organ formation in the ileum

Geng, X., Chen, L., Ahmed, Z., Formigari, G. P., Ho, Y., Gaudio, I. D., Dátilo, M. N., Azartash-Namin, Z. J., Heron, C., Shan, X., et al. (2025) · The Journal of Experimental Medicine · doi:10.1084/jem.20241799 · Cited by 16

Role of meningeal lymphatic vessels in brain homeostasis

Zhao, M.-Y., Ye, C., Liu, Y.-C., Wang, X., Fu, J.-C., Liu, X.-Y., Zhu, R., Li, Y.-Z., & Qing, T. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1593630 · Cited by 16

Vascular and Neural Response to Focal Vibration, Sensory Feedback, and Piezo Ion Channel Signaling

Penasso, H., Petersen, F., & Peternell, G. (2023) · Journal of Vascular Diseases · doi:10.3390/jvd2010006 · Cited by 17

EPHB4-RASA1 Inhibition of PIEZO1 Ras Activation Drives Lymphatic Valvulogenesis

Chen, D., Tang, Y., Lapinski, P. E., Wiggins, D., Sevick-Muraca, E. M., Davis, M. J., & King, P. D. (2024) · Circulation Research · doi:10.1161/circresaha.124.325383 · Cited by 15

Stromal regulation of tumor-associated lymphatics

Munir, H., Mazzaglia, C., & Shields, J. D. (2020) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2020.08.001 · Cited by 15

Fluid pumping of peristaltic vessel fitted with elastic valves

Wolf, K. T., Dixon, J. B., & Alexeev, A. (2021) · Journal of Fluid Mechanics · doi:10.1017/jfm.2021.302 · Cited by 13

PIEZO1 is the most common monogenic etiology of non‐immune hydrops fetalis detected by prenatal exome sequencing

Brewer, C., Makhamreh, M. M., Shivashankar, K., McLaren, R. A., Toro, M. F., Berger, S., & Al‐Kouatly, H. B. (2023) · Prenatal Diagnosis · doi:10.1002/pd.6451 · Cited by 13

Developmental progression of lymphatic valve morphology and function

Davis, M. J., Zawieja, S. D., & Yang, Y. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1331291 · Cited by 13

Alteration of Piezo1 signaling in type 2 diabetic mice: focus on endothelium and BKCa channel

Haam, C. E., Choi, S., Byeon, S., Oh, E. Y., Choi, S.-K., & Lee, Y.-H. (2024) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-024-02983-4 · Cited by 13

Digenic Inheritance of a FOXC2 Mutation and Two PIEZO1 Mutations Underlies Congenital Lymphedema in a Multigeneration Family

Mustacich, D. J., Lai, L., Bernas, M. J., Jones, J. A., Myles, R. J., Kuo, P. H., Williams, W. H., Witte, C. L., Erickson, R. P., & Witte, M. H. (2021) · The American Journal of Medicine · doi:10.1016/j.amjmed.2021.09.007 · Cited by 13

PIEZO1 variant implications for biological understanding and human health

Cheng, C. W., Earle, S. L., Povstyan, O. V., Randall, C., Smith, K. A., Debant, M., Macrae, F. L., Beech, D. G., McGrane, A., Bartoli, F., et al. (2025) · Open Biology · doi:10.1098/rsob.240345 · Cited by 12

Perceiving traumatic brain injury from glymphatic system

Yang, Z., Li, P., & Wei, J. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03126-6 · Cited by 13

Mechanical forces in lymphatic vessel development: Focus on transcriptional regulation

Ujiie, N., & Kume, T. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.1066460 · Cited by 12

Yoda1 opens the lymphatic path for craniosynostosis therapy

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Drivers and challenges in raising the achievement of pupils from Bangladeshi, Somali and Turkish backgrounds

Vorhaus, J. S., Strand, S., de Coulon, A., & Meschi, E. (2010) · Cited by 12

PIEZO Force Sensors and the HeartPreprint

McGrane, A., Murray, M., Bartoli, F., Giannoudi, M., Conning-Rowland, M. S., Stewart, L., Levelt, E., Cubbon, R. M., Dall’Armellina, E., Griffin, K. J., et al. (2025) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a041806 · Cited by 13

Loss of Primary Cilia Protein IFT20 Dysregulates Lymphatic Vessel Patterning in Development and Inflammation

Paulson, D., Harms, R., Ward, C., Latterell, M., Pazour, G. J., & Fink, D. M. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.672625 · Cited by 11

PIEZO1 ‐gene gain‐of‐function mutations with lower limb lymphedema onset in an adult: Clinical, scintigraphic, and noncontrast magnetic resonance lymphography findings

Vignes, S., Kaltenbach, S., Garçon, L., Arrivé, L., Asnafi, V., Guitton, C., Bouligand, J., Delarue, A., & Picard, V. (2021) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.62476 · Cited by 11

eNOS Regulates Lymphatic Valve Specification by Controlling β-Catenin Signaling During Embryogenesis in Mice

Iyer, D., Mastrogiacomo, D. M., Li, K., Banerjee, R., Yang, Y., & Scallan, J. P. (2023) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.123.319405 · Cited by 11

The mechanism and potential therapeutic target of piezo channels in pain

Xu, Y., Wang, Y., Mei, S., Hu, J., Wu, L., Xu, L., Bao, L., & Fang, X. (2024) · Frontiers in Pain Research · doi:10.3389/fpain.2024.1452389 · Cited by 10

Emerging roles of mechanically activated ion channels in autoimmune disease

Zeng, Z., Chen, E., & Xue, J. (2025) · Autoimmunity Reviews · doi:10.1016/j.autrev.2025.103813 · Cited by 10

PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity

Beech, D. J. (2025) · Advanced Science · doi:10.1002/advs.202511774 · Cited by 11

A novel role of Hippo-Yap/TAZ signaling pathway in lymphatic vascular development

Cha, B., Moon, S., & Kim, W. (2021) · BMB Reports · doi:10.5483/bmbrep.2021.54.6.020 · Cited by 11

Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation

Nonomura, K., Lukacs, V., Sweet, D. T., Goddard, L. M., Akemi, K., Whitwam, T., Ranade, S. S., Fujimori, T., Kahn, M. L., & Patapoutian, A. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1817070115 · Cited by 280

Mechanically activated channel PIEZO1 is required for lymphatic valve formation

Nonomura, K. (2019) · JAPANESE SOCIETY of DEVELOPMENTAL BIOLOGISTS

Piezo1 is required for calcium signaling during lymphatic valve morphogenesis

Katsuta, H., Nonomura, K., Akemi, K., Miyata, T., & Fujimori, T. (2019) · Seibutsu Butsuri

Piezo1-Regulated Mechanotransduction Controls Flow-Activated Lymphatic Expansion

Choi, D., Park, E., Yu, R. P., Cooper, M. N., Cho, I., Choi, J., Yu, J., Zhao, L., Yum, J.-E. I., Yu, J. S., et al. (2022) · Circulation Research · doi:10.1161/circresaha.121.320565 · Cited by 110

In vivo calcium signaling induced by mechanosensitive channel Piezo1 during lymphatic valve morphogenesis

Katsuta, H. (2019) · JAPANESE SOCIETY of DEVELOPMENTAL BIOLOGISTS