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Propylthiouracil inhibits the conversion of l-thyroxine to l-triiodothyronine
Open accessAbstract
6-n-propylthiouracil (PTU) administered to male Sprague-Dawley rats maintained on 2 and 5 mug L-thyroxine (T(4))/100 g body weight resulted in a marked reduction in the rate of conversion of L-thyroxine to L-triiodothyronine (T(3)). These effects could not be ascribed to induced hypothyroidism since the group maintained on 5 mug T(4)/day had normal levels of liver mitochondrial alpha glycerophosphate dehydrogenase. In confirmation of previous studies, PTU also reduced the fractional rate of deiodination of T(3). These observations provide a possible explanation of the many published observations indicating that PTU antagonizes the tissue effects of T(4) but not of T(3). The data suggest that monodeiodination of T(4) but not of T(3) is essential before hormonal effects can be manifested at the cellular level.
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“Propylthiouracil (PTU) inhibits D1, explaining some of its therapeutic benefit in this setting (14).”
From Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement (2014) · cites this paper as [14]
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Cites
Lee, Y., & Lardy, H. A. (1965) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)97593-9 · Cited by 632
Conversion of Thyroxine (T4) to triiodothyronine (T3) in athyreotic human subjects
Braverman, L. E., Ingbar, S. H., & Sterling, K. (1970) · Journal of Clinical Investigation · doi:10.1172/jci106304 · Cited by 485
THE IDENTIFICATION OF 3:5:3'-L-TRIIODOTHYRONINE IN HUMAN PLASMA
Gross, J., & Pitt‐Rivers, R. (1952) · The Lancet · doi:10.1016/s0140-6736(52)91952-1 · Cited by 298
Role of Plasma Proteins in the Binding, Distribution and Metabolism of the Thyroid Hormones
Oppenheimer, J. H. (1968) · New England Journal of Medicine · doi:10.1056/nejm196805232782107 · Cited by 270
Self-citationThe extrathyroidal conversion rate of thyroxine to triiodothyronine in normal man
Pittman, C. S., Chambers, J. B., & Read, V. H. (1971) · Journal of Clinical Investigation · doi:10.1172/jci106596 · Cited by 214
Quantitation of extrathyroidal conversion of l-thyroxine to 3,5,3′-triiodo-l-thyronine in the rat
Schwartz, H. L., Surks, M. I., & Oppenheimer, J. H. (1971) · Journal of Clinical Investigation · doi:10.1172/jci106584 · Cited by 173
Self-citationConversion of Thyroxine to Triiodothyronine in Normal Human Subjects
Sterling, K., Brenner, M. A., & Newman, E. S. (1970) · Science · doi:10.1126/science.169.3950.1099 · Cited by 131
Specific Triiodothyronine Binding Sites in the Anterior Pituitary of the Rat
Schadlow, A. R., Surks, M. I., Schwartz, H. L., & Oppenheimer, J. H. (1972) · Science · doi:10.1126/science.176.4040.1252 · Cited by 101
Self-citationANTIGOITROGENIC AND CALORIGENIC ACTIVITIES OF THYROXINE ANALOGUES IN RATS1
STASILLI, N. R., Kroc, R. L., & Meltzer, R. I. (1959) · Endocrinology · doi:10.1210/endo-64-1-62 · Cited by 92
Oppenheimer, J. H., Schwartz, H. L., Shapiro, H. C., Bernstein, G. S., & Surks, M. I. (1970) · Journal of Clinical Investigation · doi:10.1172/jci106301 · Cited by 85
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- Oppenheimer, J. H., D. Koerner, H. L. Schwartz, and M. I. Surks. Specific nuclear triiodothyronine binding sites in rat liver and kidney. J. Clin. Endocrinol. Metab. In press.
Cited by
Sorted by citations
Items 101–200 of 258
Marty, S., Sauer, U. G., Charlton, A., Ghaffari, R., Guignard, D., Hallmark, N., Hannas, B. R., Jacobi, S., Marxfeld, H., Melching‐Kollmuss, S., et al. (2022) · Critical Reviews in Toxicology · doi:10.1080/10408444.2022.2130166 · Cited by 28
SERUM TRIIODOTHYRONINE IN HEALTH AND DISEASE
Patel, Y., & Burger, H. (1973) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1973.tb01720.x · Cited by 28
The ups and downs of the thyroxine pro-hormone hypothesis
Galton, V. A. (2017) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2017.01.029 · Cited by 28
Thyroid Hormones and the Liver
Sheridan, P. M. (1983) · Clinics in Gastroenterology · doi:10.1016/s0300-5089(21)00606-4 · Cited by 26
Iodothyronines: Oxidative deiodination by hemoglobin and inhibition of lipid peroxidation
Tseng, Y. L., & Latham, K. R. (1984) · Lipids · doi:10.1007/bf02534498 · Cited by 25
Melmed, S. K., NELSON, M., Kaplowitz, N., Yamada, T., & Hershman, J. M. (1981) · Endocrinology · doi:10.1210/endo-108-3-970 · Cited by 25
Metabolism of Thyroxine in Rana catesbeiana Tadpoles during Metamorphic Climax*
Galton, V. A., & MUNCK, K. (1981) · Endocrinology · doi:10.1210/endo-109-4-1127 · Cited by 24
Thyroid hormone stimulation of lipogenesis in isolated rat hepatocytes
Gnoni, G. V., Landriscina, C., & Quagliariello, E. (1980) · Biochemical Medicine · doi:10.1016/0006-2944(80)90028-9 · Cited by 24
Yamada, T., CHOPRA, I. J., & Kaplowitz, N. (1981) · Journal of Endocrinological Investigation · doi:10.1007/bf03348299 · Cited by 24
Bantle, J. P., DILLMANN, W. H., Oppenheimer, J. H., BINGHAM, B., & Runger, G. C. (1980) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-50-2-286 · Cited by 24
Self-citationMASHITA, K., Kawamura, S., Kishino, B.-I., Kimurâ, H., Nonaka, K., & Tarui, S. (1982) · Endocrinology · doi:10.1210/endo-110-3-1023 · Cited by 23
CHOPRA, I. J., TECO, G. N. C., Eisenberg, J., Wiersinga, W. M., & Solomon, D. H. (1982) · Endocrinology · doi:10.1210/endo-110-1-163 · Cited by 21
BALSAM, A., SEXTON, F. C., & Ingbar, S. H. (1979) · Endocrinology · doi:10.1210/endo-105-5-1115 · Cited by 21
Increased Free Thyroxine in a Euthyroid Patient with Thyroxine-Binding Globulin Deficiency
PREMACHANDRA, B. N., Gossain, V. V., & Perlstein, I. B. (1976) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-42-2-309 · Cited by 21
Liu, F., Wang, K., Nie, J., Feng, Q., Li, X., Yang, Y., Deng, M., Zhou, H., & Wang, S. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.1002489 · Cited by 20
Pathak, V. K., & Chāndolā, A. (1982) · General and Comparative Endocrinology · doi:10.1016/0016-6480(82)90121-6 · Cited by 20
Osman, A. K. (1981) · Ecology of Food and Nutrition · doi:10.1080/03670244.1981.9990666 · Cited by 20
Leatherland, J. F., Barnett, B. J., Cho, C. Y., & Slinger, S. J. (1980) · Environmental Biology of Fishes · doi:10.1007/bf02391624 · Cited by 20
Regulation of thyroid hormone metabolism in rat liver fractions
Höffken, B., Ködding, R., Mühlen, A. V. Z., Hehrmann, T., Jüppner, H., & Hesch, R. D. (1978) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(78)90126-5 · Cited by 20
Britton, R. S., Koves, G., Orrego, H., Kalant, H., Phillips, M. J., Khanna, J. M., & Israel, Y. (1979) · Toxicology and Applied Pharmacology · doi:10.1016/0041-008x(79)90017-6 · Cited by 19
Coiro, V., Harris, A. R. C., GOODMAN, H. M., Vagenakis, A. G., & Braverman, L. E. (1980) · Endocrinology · doi:10.1210/endo-106-1-68 · Cited by 20
Hedgehog-mediated regulation of thyroid hormone action through iodothyronine deiodinases
Dentice, M. (2011) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.2011.553607 · Cited by 19
Triiodothyronine induces lipid oxidation and mitochondrial biogenesis in rat Harderian gland
Santillo, A., Burrone, L., Falvo, S., Senese, R., Lanni, A., & Baccari, G. C. (2013) · Journal of Endocrinology · doi:10.1530/joe-13-0127 · Cited by 19
Glatt, C. M., Ouyang, M., Welsh, W. J., Green, J. W., Connor, J. O., Frame, S. R., Everds, N. E., Poindexter, G., Snajdr, S. I., & Delker, D. A. (2005) · Environmental Health Perspectives · doi:10.1289/ehp.7690 · Cited by 19
Riedel, W. (1983) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/bf00652516 · Cited by 19
Hypothyroxinemia: a subclinical condition affecting neurodevelopment
Berbel, P. J., & Bernal, J. (2010) · Expert Review of Endocrinology & Metabolism · doi:10.1586/eem.10.37 · Cited by 19
Increased survival of rats bearing Morris hepatoma 7800 after induction of hypothyroidism.
Mishkin, S., Morris, H. P., Yalovsky, M. A., & Murthy, P. V. N. (1979) · PubMed · Cited by 19
Sustained Pituitary T3 Production Explains the T4-mediated TSH Feedback Mechanism
Batistuzzo, A., Salas-Lucia, F., Gereben, B., Ribeiro, M. O., & Bianco, A. C. (2023) · Endocrinology · doi:10.1210/endocr/bqad155 · Cited by 18
Sorimachi, K., & ROBBINS, J. J. (1979) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(79)90061-8 · Cited by 18
Williams, M. T., Carrington, H. A., & Herrera, A. (1986) · Biochemical Journal · doi:10.1042/bj2330595 · Cited by 18
Chāndolā, A., & Bhatt, D. C. (1982) · General and Comparative Endocrinology · doi:10.1016/0016-6480(82)90186-1 · Cited by 18
Biochemical Basis of Thyroid Hormone Action
Oppenheimer, J. H., & Surks, M. I. (1975) · Biochemical Actions of Hormones · doi:10.1016/b978-0-12-452803-1.50012-4 · Cited by 18
Self-citationConrad, A. H., Strafuss, J. M., Wittman, M. D., Conway, S., & Conrad, G. W. (2008) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.07-0800 · Cited by 17
SUBSTITUTION OF RAPESEED MEAL FOR SOYBEAN MEAL AS A SOURCE OF PROTEIN FOR LACTATING COWS
FISHER, L. J., & Walsh, D. S. (1976) · Canadian Journal of Animal Science · doi:10.4141/cjas76-028 · Cited by 17
NOGIMORI, T., Braverman, L. E., Taurog, A., Fang, S.-L., Wright, G. E., & Emerson, C. H. (1986) · Endocrinology · doi:10.1210/endo-118-4-1598 · Cited by 17
Weetman, A., Shepherdley, C. A., Mansell, P., Ubhi, C., & Visser, T. J. (2003) · European Journal of Endocrinology · doi:10.1530/eje.0.1490443 · Cited by 17
Molecular Mechanisms of Thyroid Hormone Action: A Physiologic Perspective
Schwartz, H. L., Strait, K. A., & Oppenheimer, J. H. (1993) · Clinics in Laboratory Medicine · doi:10.1016/s0272-2712(18)30425-6 · Cited by 17
Self-citationCHOPRA, I. J., Huang, T., HURD, R. E., & Solomon, D. H. (1984) · Endocrinology · doi:10.1210/endo-114-6-2039 · Cited by 17
Mori, Y., Nishikawa, M., Matsubara, H., Takagi, T., Toyoda, N., Oikawa, S., & Inada, M. (1990) · Endocrinology · doi:10.1210/endo-126-1-466 · Cited by 17
Biological and Biochemical Aspects of Selenium Compounds
Bhuyan, B. J., & Mugesh, G. (2011) · Wiley eBooks · doi:10.1002/9783527641949.ch9 · Cited by 17
Morphological and biochemical changes in the Harderian gland of hypothyroid rats
Monteforte, R., Santillo, A., Lanni, A., D’Aniello, S., & Baccari, G. C. (2008) · Journal of Experimental Biology · doi:10.1242/jeb.015115 · Cited by 16
Oppenheimer, J. H. (1972) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(25)07911-x · Cited by 15
Self-citationSelective suppression of neurofilament antigen expression in the hypothyroid rat cerebral cortex
Plioplys, A. V., Gravel, C., & Hawkes, R. B. (1986) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(86)90050-x · Cited by 15
Nuclear binding of T3 and effects of QO2, Na-K-ATPase, and alpha-GPDH in liver and kidney
Sömjen, D., Ismail‐Beigi, F., & Edelman, I. S. (1981) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1981.240.2.e146 · Cited by 15
Cody, V. (1978) · Elsevier eBooks · doi:10.1016/b978-0-12-571134-0.50016-8 · Cited by 15
Studies on the deiodination of thyroid hormones in Xenopus laevis tadpoles
Robinson, H., & Galton, V. A. (1976) · General and Comparative Endocrinology · doi:10.1016/0016-6480(76)90069-1 · Cited by 15
Association of thyroid hormone receptors with chromatin
Jump, D. Β., & Oppenheimer, J. H. (1983) · Molecular and Cellular Biochemistry · doi:10.1007/bf00673710 · Cited by 15
Self-citationIntrapituitary Mechanisms in the Control of TSH Secretion
Larsen, P. R., & Silva, J. E. (1983) · Elsevier eBooks · doi:10.1016/b978-0-12-527560-6.50018-4 · Cited by 15
Moreno, F. S., Petrides, A. S., Heinen, E., Strohmeyer, G. W., & Teschke, R. (1981) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1981.tb04870.x · Cited by 14
Studies on the Mechanism of Goitrogenic Action of Diphenylthiohydantoin
Tsukui, T., Aizawa, T., Yamada, T., & KAWABE, T. (1978) · Endocrinology · doi:10.1210/endo-102-6-1662 · Cited by 14
Pant, K., & Chandola‐Saklani, A. (1995) · Comparative Biochemistry and Physiology Part C Pharmacology Toxicology and Endocrinology · doi:10.1016/0742-8413(94)00072-i · Cited by 14
Effects of thyroid hormones on the ontogeny of oestradiol-binding sites in the rat
Barbanel, G., & ASSENMACHER, I. (1982) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(82)90124-1 · Cited by 14
Kharroubi, A., & Slaunwhite, W. R. (1984) · Endocrinology · doi:10.1210/endo-115-4-1283 · Cited by 14
Wang, Z., Wu, P., Yang, J., Jiang, Y., Wang, J., & Lin, C. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1323026 · Cited by 13
Prevention and management of hyperthyroid storm
DOBYNS, B. M. (1978) · World Journal of Surgery · doi:10.1007/bf01561498 · Cited by 13
Riss, T., Stewart, B. H., & Sirbasku, D. A. (1989) · In Vitro Cellular & Developmental Biology - Plant · doi:10.1007/bf02626168 · Cited by 13
Thyrotropic activity of hypophysis during aging
Gv, V., & Nv, V. (1977) · Experimental Gerontology · doi:10.1016/0531-5565(77)90016-x · Cited by 13
Structure-Activity Relationships
Arcos, J. C., & Argus, M. F. (1974) · Elsevier eBooks · doi:10.1016/b978-0-12-059302-6.50006-5 · Cited by 12
Bendrath, F., Specowius, V., Michalik, D., & Langer, P. (2012) · Tetrahedron · doi:10.1016/j.tet.2012.05.119 · Cited by 12
Eil, C., & CHESTUNT, R. Y. (1985) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-60-3-548 · Cited by 12
Sabatino, L., Kusmic, C., & Iervasi, G. (2020) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-020-03873-w · Cited by 11
The goitrogenic effect of two Sudanese pearl millet cultivars in rats
Elnour, A. A., Liedén, S.-Å., Bourdoux, P., Eltom, M. A., Khalid, S. A., & Hambræus, L. (1997) · Nutrition Research · doi:10.1016/s0271-5317(97)00015-8 · Cited by 11
Triiodothyronine and thyroxine interrelationships in health and disease.
Walfish, P. G. (1976) · PubMed Central · Cited by 11
Structure activity relationships of thyroxine analogs
Jorgensen, E. C. (1976) · Pharmacology & Therapeutics Part B General and Systematic Pharmacology · doi:10.1016/0306-039x(76)90073-8 · Cited by 11
INTERACTION OF DRUGS WITH THYROID HORMONE BINDING SITES*
Oppenheimer, J. H. (1973) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1973.tb20494.x · Cited by 11
Self-citationTONOOKA, N., & Greer, M. A. (1980) · Endocrinology · doi:10.1210/endo-106-3-818 · Cited by 11
What is the best test for monitoring levothyroxine therapy?
Wong, M. M., & Volpé, R. (1981) · PubMed Central · Cited by 10
Theodoro, J. M. V., Martinez, O. D. M., Grancieri, M., Toledo, R. C. L., Binoti, M. L., Martins, A. M. D., de Carvalho, C. W. P., Lisboa, P. C., & Martino, H. S. D. (2021) · Food & Function · doi:10.1039/d0fo03388j · Cited by 9
Type I Iodothyronine Deiodinase: Unexpected Complexities in a Simple Deiodination Reaction
Larsen, P. R., & Berry, M. J. (1994) · Thyroid · doi:10.1089/thy.1994.4.357 · Cited by 9
The Laboratory Diagnosis of Thyroid Disorders
WELLBY, M. L. (1976) · Advances in clinical chemistry · doi:10.1016/s0065-2423(08)60297-8 · Cited by 11
Saad, N. S., Repas, S. J., Floyd, K. T., Janssen, P. M. L., & Elnakish, M. T. (2017) · BioMed Research International · doi:10.1155/2017/6071031 · Cited by 9
Barsano, C. P., Garces, J., & Iqbal, Z. (1994) · Biological Psychiatry · doi:10.1016/0006-3223(94)91144-4 · Cited by 9
Prevention of organomercurial intoxication by thyroid deficiency in the rat
Szabó, S., Kourounakis, P., Kovács, K., Tuchweber, B., & Garg, B. D. (1974) · Toxicology and Applied Pharmacology · doi:10.1016/0041-008x(74)90089-1 · Cited by 9
Santillo, A., Burrone, L., Ferrara, D., Minucci, S., Pinelli, C., & Baccari, G. C. (2012) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2012.07.014 · Cited by 8
Weiss, R. E., & Refetoff, S. (2015) · Elsevier eBooks · doi:10.1016/b978-0-323-18907-1.00078-0 · Cited by 8
McClung, M. R., & Greer, M. A. (1980) · Annual Review of Medicine · doi:10.1146/annurev.me.31.020180.002125 · Cited by 8
Schaffer, W. T., Denckla, W. D., & Veech, R. L. (1980) · Springer eBooks · doi:10.1007/978-1-4757-1419-7_61 · Cited by 8
Thyroid function tests in nonthyroidal disease
Oppenheimer, J. H. (1982) · Journal of Chronic Diseases · doi:10.1016/0021-9681(82)90093-5 · Cited by 7
Self-citationHypocalcemia Accompanying Agranulocytosis During Propylthiouracil Therapy
Shambaugh, G. E., Khoury, N., Zonschein, J., & Sizemore, G. W. (1979) · Annals of Internal Medicine · doi:10.7326/0003-4819-91-4-576 · Cited by 7
Clay, V. J., & RAGAN, C. I. (1989) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(89)80208-7 · Cited by 7
STUDIES ON THE CONTROL OF THYROTROPHIN SECRETION IN NORMAL MAN
Vice, P., CLARK, F., Schardt, W., & Evered, D. C. (1976) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1976.tb01980.x · Cited by 7
Iodothyronine deiodination in the canine thyroid
Laurberg, P. (1984) · Domestic Animal Endocrinology · doi:10.1016/0739-7240(84)90008-0 · Cited by 7
Sato, T., Maruyama, S., & NOMURA, K. (1981) · Endocrinologia Japonica · doi:10.1507/endocrj1954.28.451 · Cited by 7
Age and hypothyroidism affect dopamine modulation of breathing and D2 receptor levels
Sykora, C., Amor, M., & Schlenker, E. H. (2012) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2012.10.004 · Cited by 6
Aizawa, T., Yamada, T., Tawata, M., Shimizu, T., Furuta, S., Kiyosawa, K., & Yakata, M. (1980) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1980.tb01126.x · Cited by 6
The History of 3,5,3′-Triiodothyronine
Galton, V. A. (2012) · Thyroid · doi:10.1089/thy.2012.0462 · Cited by 6
Davies, T. F. (2022) · Thyroid · doi:10.1089/thy.2022.0012 · Cited by 6
Heinen, E., Herrmann, J., Mosny, D., Moreno, F. S., Teschke, R., & Krüskemper, H. L. (1981) · Journal of Endocrinological Investigation · doi:10.1007/bf03349453 · Cited by 6
Mast cell population in the frog brain: distribution and influence of thyroid status
Monteforte, R., Pinelli, C., Santillo, A., Rastogi, R. K., Polese, G., & Baccari, G. C. (2010) · Journal of Experimental Biology · doi:10.1242/jeb.039628 · Cited by 6
Effects of Thyroxine on Rat Brown Fat and Muscle Thermogenesis in the Cold
Zaninovich, Á. A., Rebagliati, I., Raı́ces, M., Ricci, C. R., & Hagmüller, K. (2000) · Endocrine Research · doi:10.3109/07435800009066164 · Cited by 6
The Peripheral Action of the Thyroid Hormones
Oppenheimer, J. H., & Surks, M. I. (1975) · Medical Clinics of North America · doi:10.1016/s0025-7125(16)31956-3 · Cited by 6
Self-citationEFFECT OF CHRONIC ALCOHOL AND OXYGEN TENSION ON THE DEVELOPMENT OF HEPATIC NECROSIS IN RAT
Christensen, E., Craig, J., Harris, R. A., Higgins, J., Edmondson, H. A., & Veech, R. L. (1977) · Elsevier eBooks · doi:10.1016/b978-0-12-691403-0.50013-6 · Cited by 6
Cook, D. B., Tolman, K. G., & Gray, P. D. (1983) · Biochemical Pharmacology · doi:10.1016/0006-2952(83)90463-x · Cited by 6
Beylot, M., Riou, J. P., Borson‐Chazot, F., Cohen, R., Sautot, G., & Mornex, R. (1984) · Metabolism · doi:10.1016/0026-0495(84)90091-x · Cited by 6
Kampmann, J., & Hansen, M. J. (1981) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.1981.tb01289.x · Cited by 6
Regulation of Genetic Activity by Thyroid Hormones
Abdukarimov, A. (1983) · Elsevier eBooks · doi:10.1016/b978-0-12-364376-6.50008-9 · Cited by 6
Bürgi, H., & Labhart, A. (1974) · Springer eBooks · doi:10.1007/978-3-642-96158-8_6 · Cited by 6
Dilman, V. M., & Berstein, L. M. (1979) · Experimental Gerontology · doi:10.1016/0531-5565(79)90033-0 · Cited by 5
Berbel, P. J., & de Escobar, G. M. (2011) · Springer eBooks · doi:10.1007/978-0-387-92271-3_135 · Cited by 5
Yoshimasa, Y., & Hamada, S. (1983) · Biochemical Journal · doi:10.1042/bj2100331 · Cited by 5
Metadata
- Authors
- Oppenheimer, J. H., Schwartz, H. L., & Surks, M. I.
- Affiliations
- Albert Einstein College of Medicine (US)
- Venue
- Journal of Clinical Investigation
- Published
- 1972-09-01
- Volume
- 51
- Issue
- 9
- Pages
- 2493-2497
- ISSN
- 0021-9738 (ISSN-L)
- PMC
- PMC292418
- OpenAlex
- W1758817371
- Cited by
- 258
- References
- 36
- Citations by year
- 2024: 3 · 2023: 2 · 2022: 5 · 2021: 1 · 2020: 2 · 2019: 1 · 2018: 1 · 2017: 3 · 2016: 2 · 2015: 3 · 2014: 4 · 2013: 2 · 2012: 6
- FWCI
- 16.77
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Investigation (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Health Research Council of the City of New York
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Chemical Analysis and Environmental Impact
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Cancer Diagnosis and Treatment
- Keywords
- propylthiouracil, levothyroxine, triiodothyronine, T4 to T3 conversion, deiodination, thyroid hormone antagonism, alpha-glycerophosphate dehydrogenase, liver mitochondria, hypothyroidism
- MeSH terms
- Administration, Oral, Animals, Chromatography, Paper, Chromatography, Thin Layer, Glucosephosphate Dehydrogenase, Injections, Subcutaneous, Iodine Radioisotopes, Male, Mitochondria, Liver, Propylthiouracil, Thyroidectomy, Thyroxine, Triiodothyronine, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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