Propylthiouracil inhibits the conversion of l-thyroxine to l-triiodothyronine

Influence of Thyroid Hormones on l-α-Glycerophosphate Dehydrogenases and Other Dehydrogenases in Various Organs of the Rat

Lee, Y., & Lardy, H. A. (1965) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)97593-9 · Cited by 632

Conversion of Thyroxine (T4) to triiodothyronine (T3) in athyreotic human subjects

Braverman, L. E., Ingbar, S. H., & Sterling, K. (1970) · Journal of Clinical Investigation · doi:10.1172/jci106304 · Cited by 485

THE IDENTIFICATION OF 3:5:3'-L-TRIIODOTHYRONINE IN HUMAN PLASMA

Gross, J., & Pitt‐Rivers, R. (1952) · The Lancet · doi:10.1016/s0140-6736(52)91952-1 · Cited by 298

Role of Plasma Proteins in the Binding, Distribution and Metabolism of the Thyroid Hormones

Oppenheimer, J. H. (1968) · New England Journal of Medicine · doi:10.1056/nejm196805232782107 · Cited by 270

The extrathyroidal conversion rate of thyroxine to triiodothyronine in normal man

Pittman, C. S., Chambers, J. B., & Read, V. H. (1971) · Journal of Clinical Investigation · doi:10.1172/jci106596 · Cited by 214

Quantitation of extrathyroidal conversion of l-thyroxine to 3,5,3′-triiodo-l-thyronine in the rat

Schwartz, H. L., Surks, M. I., & Oppenheimer, J. H. (1971) · Journal of Clinical Investigation · doi:10.1172/jci106584 · Cited by 173

Conversion of Thyroxine to Triiodothyronine in Normal Human Subjects

Sterling, K., Brenner, M. A., & Newman, E. S. (1970) · Science · doi:10.1126/science.169.3950.1099 · Cited by 131

Specific Triiodothyronine Binding Sites in the Anterior Pituitary of the Rat

Schadlow, A. R., Surks, M. I., Schwartz, H. L., & Oppenheimer, J. H. (1972) · Science · doi:10.1126/science.176.4040.1252 · Cited by 101

ANTIGOITROGENIC AND CALORIGENIC ACTIVITIES OF THYROXINE ANALOGUES IN RATS1

STASILLI, N. R., Kroc, R. L., & Meltzer, R. I. (1959) · Endocrinology · doi:10.1210/endo-64-1-62 · Cited by 92

Differences in primary cellular factors influencing the metabolism and distribution of 3,5,3′-L-triiodothyronine and L-thyroxine

Oppenheimer, J. H., Schwartz, H. L., Shapiro, H. C., Bernstein, G. S., & Surks, M. I. (1970) · Journal of Clinical Investigation · doi:10.1172/jci106301 · Cited by 85

Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement

Jonklaas, J., Bianco, A. C., Bauer, A. J., Burman, K. D., Cappola, A. R., Celi, F. S., Cooper, D. S., Kim, B. W., Peeters, R. P., Rosenthal, M. S., et al. (2014) · Thyroid® · doi:10.1089/thy.2014.0028 · Cited by 1,928

Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases

Bianco, A. C., Salvatore, D., Gereben, B., Berry, M. J., & Larsen, P. R. (2002) · Endocrine Reviews · doi:10.1210/edrv.23.1.0455 · Cited by 1,853

Cellular and Molecular Basis of Deiodinase-Regulated Thyroid Hormone Signaling1

Gereben, B., Zavacki, A. M., Ribich, S., Kim, B. W., Huang, S. A., Simonides, W. S., Zeöld, A., & Bianco, A. C. (2008) · Endocrine Reviews · doi:10.1210/er.2008-0019 · Cited by 891

Type I iodothyronine deiodinase is a selenocysteine-containing enzyme

Berry, M. J., Banu, L., & Larsen, P. R. (1991) · Nature · doi:10.1038/349438a0 · Cited by 883

Relationships between Circulating and Intracellular Thyroid Hormones: Physiological and Clinical Implications*

Larsen, P. R., Silva, J. E., & Kaplan, M. M. (1981) · Endocrine Reviews · doi:10.1210/edrv-2-1-87 · Cited by 546

Adrenergic activation of triiodothyronine production in brown adipose tissue

Silva, J. E., & Larsen, P. R. (1983) · Nature · doi:10.1038/305712a0 · Cited by 401

Thyroid-Pituitary Interaction: Feedback Regulation of Thyrotropin Secretion by Thyroid Hormones

Bleich, H. L., Moore, M. J., & Larsen, P. R. (1982) · New England Journal of Medicine · doi:10.1056/nejm198201073060107 · Cited by 357

Iodothyronine Metabolism in Rat Liver Homogenates

Kaplan, M. M., & Utiger, R. D. (1978) · Journal of Clinical Investigation · doi:10.1172/jci108957 · Cited by 312

Defining the Roles of the Iodothyronine Deiodinases: Current Concepts and Challenges

Germain, D. L. S., Galton, V. A., & Hernández, A. (2009) · Endocrinology · doi:10.1210/en.2008-1588 · Cited by 303

A Radioimmunoassay for Measurement of 3,3′, 5′-Triiodothyronine (Reverse T3)

CHOPRA, I. J. (1974) · Journal of Clinical Investigation · doi:10.1172/jci107795 · Cited by 247

Experimental alcohol-induced hepatic necrosis: suppression by propylthiouracil.

Israel, Y., Kalant, H., Orrego, H., Khanna, J. M., Videla, L. A., & Phillips, J. M. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.3.1137 · Cited by 237

Determination of iodothyronine absorption and conversion of L-thyroxine (T4) to L-triiodothyronine (T3) using turnover rate techniques

Surks, M. I., Schadlow, A. R., Stock, J. M., & Oppenheimer, J. H. (1973) · Journal of Clinical Investigation · doi:10.1172/jci107244 · Cited by 223

Contributions of Plasma Triiodothyronine and Local Thyroxine Monodeiodination to Triiodothyronine to Nuclear Triiodothyronine Receptor Saturation in Pituitary, Liver, and Kidney of Hypothyroid Rats

Silva, J. E., & Larsen, P. R. (1978) · Journal of Clinical Investigation · doi:10.1172/jci109041 · Cited by 208

Activation and inactivation of thyroid hormone by deiodinases: Local action with general consequences

Gereben, B., Zeöld, A., Dentice, M., Salvatore, D., & Bianco, A. C. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-007-7396-0 · Cited by 207

Potential of brown adipose tissue type II thyroxine 5'-deiodinase as a local and systemic source of triiodothyronine in rats.

Silva, J. E., & Larsen, P. R. (1985) · Journal of Clinical Investigation · doi:10.1172/jci112239 · Cited by 207

Selenocysteine confers the biochemical properties characteristic of the type I iodothyronine deiodinase

Berry, M. J., Kieffer, J. D., Harney, J. W., & Larsen, P. R. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)98657-6 · Cited by 202

The Relationship between Serum Triiodothyronine and Thyrotropin during Systemic Illness*

Bacci, V., Schussler, G. C., & KAPLAN, T. B. (1982) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-54-6-1229 · Cited by 200

Pituitary nuclear 3,5,3’-triiodothyronine and thyrotropin secretion: an explanation for the effect of thyroxine

Silva, J. E., & Larsen, P. R. (1977) · Science · doi:10.1126/science.199941 · Cited by 198

Propylthiouracil blocks extrathyroidal conversion of thyroxine to triiodothyronine and augments thyrotropin secretion in man.

Geffner, D. L., Azukizawa, M., & Hershman, J. M. (1975) · Journal of Clinical Investigation · doi:10.1172/jci107925 · Cited by 192

A New Radioimmunoassay for Plasma l-Triiodothyronine: Measurements in Thyroid Disease and in Patients Maintained on Hormonal Replacement

Surks, M. I., Schadlow, A. R., & Oppenheimer, J. H. (1972) · Journal of Clinical Investigation · doi:10.1172/jci107137 · Cited by 188

Limited Capacity Binding Sites for l-Triiodothyronine in Rat Liver Nuclei

Surks, M. I., Koerner, D. R., Dillman, W. H., & Oppenheimer, J. H. (1973) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)43362-0 · Cited by 184

Replacement Dosage of L-Thyroxine in Hypothyroidism: A Re-Evaluation

Stock, J. M., Surks, M. I., & Oppenheimer, J. H. (1974) · New England Journal of Medicine · doi:10.1056/nejm197403072901001 · Cited by 184

Methimazole Treatment of 262 Cats With Hyperthyroidism

Peterson, M. E., Kintzer, P. P., & Hurvitz, A. I. (1988) · Journal of Veterinary Internal Medicine · doi:10.1111/j.1939-1676.1988.tb02812.x · Cited by 176

The Influence of Fasting, Diabetes, and Several Pharmacological Agents on the Pathways of Thyroxine Metabolism in Rat Liver

Balsam, A., Ingbar, S. H., & SEXTON, F. C. (1978) · Journal of Clinical Investigation · doi:10.1172/jci109143 · Cited by 168

Nuclear Receptors and the Initiation of Thyroid Hormone Action

Oppenheimer, J. H., Schwartz, H. L., Surks, M. I., Koerner, D. R., & DILLMANN, W. H. (1976) · Elsevier eBooks · doi:10.1016/b978-0-12-571132-6.50029-4 · Cited by 166

Limited Binding Capacity Sites for l-Triiodothyronine in Rat Liver Nuclei

Oppenheimer, J. H., Schwartz, H. L., Koerner, D. R., & Surks, M. I. (1974) · Journal of Clinical Investigation · doi:10.1172/jci107615 · Cited by 159

Triiodothyronine and Thyroxine in Hyperthyroidism COMPARISON OF THE ACUTE CHANGES DURING THERAPY WITH ANTITHYROID AGENTS

Abuid, J., & Larsen, P. R. (1974) · Journal of Clinical Investigation · doi:10.1172/jci107744 · Cited by 156

Thyroidal and Peripheral Production of Thyroid Hormones

Schimmel, M., & UTIGER, R. D. (1977) · Annals of Internal Medicine · doi:10.7326/0003-4819-87-6-760 · Cited by 152

Inhibition of intrapituitary thyroxine to 3.5.3'-triiodothyronine conversion prevents the acute suppression of thyrotropin release by thyroxine in hypothyroid rats.

Larsen, P. R., Dick, T. E., Markovitz, B. P., Kaplan, M. M., & Gard, T. G. (1979) · Journal of Clinical Investigation · doi:10.1172/jci109430 · Cited by 149

Triiodothyronine and Thyroxine in the Serum and Thyroid Glands of Iodine-Deficient Rats

Abrams, G., & Larsen, P. R. (1973) · Journal of Clinical Investigation · doi:10.1172/jci107443 · Cited by 146

A novel retinoid X receptor-independent thyroid hormone response element is present in the human type 1 deiodinase gene

Toyoda, N., Zavacki, A. M., Maia, A. L., Harney, J. W., & Larsen, P. R. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.9.5100 · Cited by 142

Evidence for Two Tissue-specific Pathways for In Vivo Thyroxine 5′-Deiodination in the Rat

Silva, J. E., Leonard, J. L., Crantz, F. R., & Larsen, P. R. (1982) · Journal of Clinical Investigation · doi:10.1172/jci110554 · Cited by 143

Reduction in extrathyroidal triiodothyronine production by propylthiouracil in man.

Saberi, M., Sterling, F. H., & Utiger, R. D. (1975) · Journal of Clinical Investigation · doi:10.1172/jci107924 · Cited by 138

Developmental hormonal profiles accompanying the neonatal hypothyroidism-induced increase in adult testicular size and sperm production in the rat

Kirby, J. D., Jetton, A. E., Cooke, P. S., Hess, R. A., Bunick, D., Ackland, J. F., Turek, F. W., & Schwartz, N. B. (1992) · Endocrinology · doi:10.1210/endo.131.2.1639007 · Cited by 140

Effects of thyroid hormones on enzymes involved in fatty acid and glycerolipid synthesis

Roncari, D., & Murthy, V. (1975) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)41396-3 · Cited by 137

Conversion of thyroxine into tri-iodothyronine by rat liver homogenate

Visser, T. J., Does-Tobé, I. V. D., Docter, R., & HENNEMANN, G. (1975) · Biochemical Journal · doi:10.1042/bj1500489 · Cited by 126

Concentration of l-Thyroxine and l-Triiodothyronine Specifically Bound to Nuclear Receptors in Rat Liver and Kidney

Surks, M. I., & Oppenheimer, J. H. (1977) · Journal of Clinical Investigation · doi:10.1172/jci108807 · Cited by 124

Euthyroid Hyperthyroxinemia

Borst, G. C., EIL, C., & BURMAN, K. D. (1983) · Annals of Internal Medicine · doi:10.7326/0003-4819-98-3-366 · Cited by 122

The Role of Selenium in Thyroid Hormone Action*

Berry, M. J., & Larsen, P. R. (1992) · Endocrine Reviews · doi:10.1210/edrv-13-2-207 · Cited by 119

Cloning and in vitro expression of the human selenoprotein, type I iodothyronine deiodinase

Mandel, S. J., Berry, M. J., Kieffer, J. D., Harney, J. W., Warne, R. L., & Larsen, P. R. (1992) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.75.4.1400883 · Cited by 114

The relationship between heat production and concentrations of plasma thyroid hormones in the domestic hen

KLANDORF, H., Sharp, P. J., & MacLeod, M. G. (1981) · General and Comparative Endocrinology · doi:10.1016/0016-6480(81)90056-3 · Cited by 116

Role of the Iodothyronine Deiodinases in the Physiology and Pathophysiology of Thyroid Hormone Action

Larsen, P. R., & Zavacki, A. M. (2012) · European Thyroid Journal · doi:10.1159/000343922 · Cited by 119

The Influence of β-Adrenoceptor Blocking Agents on Plasma Thyroxine and Triiodothyronine

Wiersinga, W. M., & TOUBER, J. L. (1977) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-45-2-293 · Cited by 113

THE ACTION OF THYROID HORMONE

Bernal, J., & Refetoff, S. (1977) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1977.tb03319.x · Cited by 112

Qualitative and quantitative differences in the pathways of extrathyroidal triiodothyronine generation between euthyroid and hypothyroid rats.

Silva, J. E., Gordon, M. B., Crantz, F. R., Leonard, J. L., & Larsen, P. R. (1984) · Journal of Clinical Investigation · doi:10.1172/jci111313 · Cited by 111

Effect of thyroid hormone analogues on the displacement of 125I-L-triiodothyronine from hepatic and heart nuclei in vivo: Possible relationship to hormonal activity

Oppenheimer, J. H., Schwartz, H. L., Dillman, W. H., & Surks, M. I. (1973) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(73)91177-7 · Cited by 101

The Role of Sulfhydryl Groups on the Impaired Hepatic 3′,3,5-Triiodothyronine Generation from Thyroxine in the Hypothyroid, Starved, Fetal, and Neonatal Rodent

Harris, A. R. C., Fang, S.-L., Hinerfeld, L., Braverman, L. E., & Vagenakis, A. G. (1979) · Journal of Clinical Investigation · doi:10.1172/jci109330 · Cited by 98

Thyroid Hormones in Alcoholic Liver Disease

Israel, Y., Walfish, P. G., Orrego, H., Blake, J. E., & Kalant, H. (1979) · Gastroenterology · doi:10.1016/s0016-5085(79)80137-7 · Cited by 94

Sequential deiodination of thyroxine in rat liver homogenate

Visser, T. J., Fekkes, D., Docter, R., & HENNEMANN, G. (1978) · Biochemical Journal · doi:10.1042/bj1740221 · Cited by 91

Clinical Pharmacokinetics of Antithyroid Drugs

Kampmann, J. P., & Hansen, J. (1981) · Clinical Pharmacokinetics · doi:10.2165/00003088-198106060-00001 · Cited by 91

Regulation of Type 1 Iodothyronine Deiodinase in Health and Disease

Koenig, R. J. (2005) · Thyroid · doi:10.1089/thy.2005.15.835 · Cited by 90

Sources of Circulating 3,5,3′-Triiodothyronine in Hyperthyroidism Estimated after Blocking of Type 1 and Type 2 Iodothyronine Deiodinases

Laurberg, P., Vestergaard, H., Nielsen, S., Christensen, S. E., Seefeldt, T., Helleberg, K., & Pedersen, K. M. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-0178 · Cited by 90

Developmental neurotoxicity of Propylthiouracil (PTU) in rats: Relationship between transient hypothyroxinemia during development and long-lasting behavioural and functional changes

Axelstad, M., Hansen, P. R., Boberg, J., Bonnichsen, M., Nellemann, C., Lund, S. P., ­Hougaard, K. S., & Hass, U. (2008) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2008.05.020 · Cited by 89

Does selenium supplementation affect thyroid function? Results from a randomized, controlled, double-blinded trial in a Danish population

Winther, K. H., Bonnema, S. J., Cold, F., Debrabant, B., Nybo, M., Cold, S., & Hegedüs, L. (2015) · European Journal of Endocrinology · doi:10.1530/eje-15-0069 · Cited by 88

An Evo-Devo Approach to Thyroid Hormones in Cerebral and Cerebellar Cortical Development: Etiological Implications for Autism

Berbel, P. J., Navarro, D., & Román, G. C. (2014) · Frontiers in Endocrinology · doi:10.3389/fendo.2014.00146 · Cited by 87

Physiological and genetic analyses of inbred mouse strains with a type I iodothyronine 5' deiodinase deficiency.

Berry, M. J., Grieco, D., Taylor, B. A., Maia, A. L., Kieffer, J. D., Beamer, W. G., Glover, E. A., Poland, A., & Larsen, P. R. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116730 · Cited by 86

Thyroid Storm and Its Management

Mackin, J. F., Canary, J. J., & Pittman, C. S. (1974) · New England Journal of Medicine · doi:10.1056/nejm197412262912607 · Cited by 86

Mechanisms governing the relative proportions of thyroxine and 3,5,3’-triiodothyronine in thyroid secretion

Laurberg, P. (1984) · Metabolism · doi:10.1016/0026-0495(84)90203-8 · Cited by 84

Calorigenic effect of diiodothyronines in the rat.

Lanni, A., Moreno, M., Lombardi, A., & Goglia, F. (1996) · The Journal of Physiology · doi:10.1113/jphysiol.1996.sp021536 · Cited by 76

Goitrogens and thyroid follicular cell neoplasia: Evidence for a threshold process

Paynter, O. E., Burin, G. J., Jaeger, R. B., & Gregorio, C. A. (1988) · Regulatory Toxicology and Pharmacology · doi:10.1016/0273-2300(88)90009-8 · Cited by 77

Acute Effects of Propylthiouracil (PTU) on Thyroidal Iodide Organification and Peripheral Iodothyronine Deiodination: Correlation with Serum PTU Levels Measured by Radioimmunoassay*

COOPER, D. S., SAXE, V. C., MESKELL, M., MALOOF, F., & RIDGWAY, E. C. (1982) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-54-1-101 · Cited by 76

The involvement of pineal gland and melatonin in immunity and aging I. Thymus-mediated, immunoreconstituting and antiviral activity of thyrotropin-releasing hormone

Pierpaoli, W., & Yi, C. (1990) · Journal of Neuroimmunology · doi:10.1016/0165-5728(90)90059-v · Cited by 76

Thyroid Hormone Metabolism and the Source of Plasma Triiodothyronine in 2-Week-Old Rats: Effects of Thyroid Status*

Silva, J. E., & Matthews, P. S. (1984) · Endocrinology · doi:10.1210/endo-114-6-2394 · Cited by 72

Conversion of L-Thyroxine to Triiodothyronine in Rat Kidney Homogenate*

CHIRASEVEENUPRAPUND, P., Buergi, U., GOSWAMI, A., & Rosenberg, I. N. (1978) · Endocrinology · doi:10.1210/endo-102-2-612 · Cited by 72

Development of thermoregulation in infancy: possible implications for SIDS.

Fleming, P. J., Azaz, Y., & Wigfield, R. (1992) · PubMed · Cited by 71

Maturation of the corpus callosum of the rat: I. Influence of thyroid hormones on the topography of callosal projections

Gravel, C., & Hawkes, R. B. (1990) · The Journal of Comparative Neurology · doi:10.1002/cne.902910109 · Cited by 70

Adenosine 3',5'-monophosphate and thyroid hormone control of uncoupling protein messenger ribonucleic acid in freshly dispersed brown adipocytes

Bianco, A. C., Kieffer, J. D., & Silva, J. E. (1992) · Endocrinology · doi:10.1210/endo.130.5.1374009 · Cited by 68

Estrogen effects on thyroid iodide uptake and thyroperoxidase activity in normal and ovariectomized rats

Lima, L. P., Barros, I. A., Lisboa, P. C., Araújo, R. L., da Silva, A. C. M., Rosenthal, D., Ferreira, A. C. F., & de Carvalho, D. P. (2006) · Steroids · doi:10.1016/j.steroids.2006.03.007 · Cited by 66

Evidence against a Major Role of L-Thyroxine at the Pituitary Level: Studies in Rats Treated with Iopanoic Acid (Telepaque)*

Obregón, M.-J., Pascual, A., Mallol, J., ESCOBAR, M. D. G., & del Rey, F. E. (1980) · Endocrinology · doi:10.1210/endo-106-6-1827 · Cited by 66

Antithyroid effects of propylthiouracil and sulfamonomethoxine in rats and monkeys

Takayama, S., Aihara, K., Onodera, T., & Akimoto, T. (1986) · Toxicology and Applied Pharmacology · doi:10.1016/0041-008x(86)90194-8 · Cited by 64

Type 2 Iodothyronine Deiodinase Transgene Expression in the Mouse Heart Causes Cardiac-Specific Thyrotoxicosis

Pachucki, J., Hopkins, J., Peeters, R. P., Tu, H. M., Carvalho, S. D., Kaulbach, H. C., Abel, E. D., Wondisford, F. E., Ingwall, J. S., & Larsen, P. R. (2001) · Endocrinology · doi:10.1210/endo.142.1.7907 · Cited by 65

Cytophysiology of Thyroid Parafollicular Cells

Nunez, E. A., & Gershon, M. D. (1978) · International review of cytology · doi:10.1016/s0074-7696(08)60753-6 · Cited by 61

Reduced Hippocampal Brain-Derived Neurotrophic Factor (BDNF) in Neonatal Rats after Prenatal Exposure to Propylthiouracil (PTU)

Chakraborty, G., Magagna‐Poveda, A., Parratt, C., Umans, J. G., MacLusky, N. J., & Scharfman, H. E. (2012) · Endocrinology · doi:10.1210/en.2011-1437 · Cited by 59

Are Iodine-Deficient Rats Euthyroid*

Santisteban, P., Obregón, M.-J., Rodríguez‐Peña, A., Lamas, L., del Rey, F. E., & de Escobar, G. M. (1982) · Endocrinology · doi:10.1210/endo-110-5-1780 · Cited by 60

CONGENITAL EUTHYROID GOITRE AND PARTIAL PERIPHERAL RESISTANCE TO THYROID HORMONES

Lamberg, B. ‐. (1973) · The Lancet · doi:10.1016/s0140-6736(73)91421-9 · Cited by 59

Direct Measurement of the Contributions of Type I and Type II 5'-Deiodinases to Whole Body Steady State 3,5,3'-Triiodothyronine Production from Thyroxine in the Rat

Nguyen, T. T., Chapa, F., & DiStefano, J. J. (1998) · Endocrinology · doi:10.1210/endo.139.11.6323 · Cited by 57

Correlation of serum triiodothyronine (T3) and thyroxine (T4) with biologic effects of thyroid hormone replacement in propylthiouracil-treated rats

Frumess, R. D., & Larsen, P. R. (1975) · Metabolism · doi:10.1016/0026-0495(75)90079-7 · Cited by 56

Hypothyroidism and Its Rapid Correction Alter Cardiac Remodeling

Hajje, G., Saliba, Y., Itani, T. M., Moubarak, M., Aftimos, G., & Farès, N. (2014) · PLoS ONE · doi:10.1371/journal.pone.0109753 · Cited by 51

The Effect of Thyroidectomy, Hypophysectomy, and Hormone Replacement on the Formation of Triiodothyronine from Thyroxine in Rat Liver and Kidney*

BALSAM, A., SEXTON, F. C., & Ingbar, S. H. (1978) · Endocrinology · doi:10.1210/endo-103-5-1759 · Cited by 51

Identification of the dynamics of thyroid hormone metabolism

DiStefano, J. J., Wilson, K. C., JANG, M., & Mak, P. H. (1975) · Automatica · doi:10.1016/0005-1098(75)90056-4 · Cited by 47

Evolving concepts of thyroid hormone action

Oppenheimer, J. H. (1999) · Biochimie · doi:10.1016/s0300-9084(99)80107-2 · Cited by 45

Physiologic and biochemical actions of thyroid hormone

Schwartz, H. L., & Oppenheimer, J. H. (1978) · Pharmacology & Therapeutics Part B General and Systematic Pharmacology · doi:10.1016/s0306-039x(78)80002-6 · Cited by 46

Neonatal hypothyroidism and goiter in oneinfant of each of two sets of twins due to maternal therapy with antithyroid drugs

Refetoff, S., Ochi, Y., Selenkow, H. A., & Rosenfield, R. L. (1974) · The Journal of Pediatrics · doi:10.1016/s0022-3476(74)80404-x · Cited by 45

Studies on the conversion of thyroxine to 3,5,3′-triiodothyronine in normal and thyroidectomized chickens

Rudas, P., & Pethes, G. (1984) · General and Comparative Endocrinology · doi:10.1016/0016-6480(84)90211-9 · Cited by 43

Antithyroid drugs

Marchant, B., LEES, J. F. H., & Alexander, W. D. (1978) · Pharmacology & Therapeutics Part B General and Systematic Pharmacology · doi:10.1016/s0306-039x(78)80001-4 · Cited by 42

Studies on the goitrogenic mechanism of action of N,N,N′,N′-tetramethylthiourea

Freyberger, A., & Ahr, H. J. (2005) · Toxicology · doi:10.1016/j.tox.2005.09.005 · Cited by 41

Effects of photoperiod and temperature on testicular and thyroid activity of the Japanese quail

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Treatment of dopamine-dependent shock with triiodothyronine

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