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Cited by 159

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Postprandial plasma retinyl ester response is greater in older subjects compared with younger subjects. Evidence for delayed plasma clearance of intestinal lipoproteins.

Open access
Krasinski, S D, Cohn, J S, Schaefer, E J, Russell, R M·1990·Journal of Clinical Investigation

Abstract

Postprandial vitamin A and intestinal lipoprotein metabolism was studied in 86 healthy men and women, aged 19-76 yr. Three independent experiments were carried out. In the first experiment, a supplement dose of vitamin A (3,000 retinol equivalents [RE]) was given without a meal to 59 subjects, aged 22-76 yr. In the second experiment, 20 RE/kg body wt was given with a fat-rich meal (1 g fat/kg body wt) to seven younger subjects (aged less than 50 yr) and seven older subjects (aged greater than or equal to 50 yr). In both experiments, postprandial plasma retinyl ester response increased significantly with advancing age (P less than 0.05). In the third experiment, retinyl ester-rich plasma was infused intravenously into nine young adult subjects (aged 18-30 yr) and nine elderly subjects (aged greater than or equal to 60 yr), and the rate of retinyl ester disappearance from plasma during the subsequent 3 h was determined. Mean (+/- SE) plasma retinyl ester residence time was 31 +/- 4 min in the young adult subjects vs. 57 +/- 8 min in the elderly subjects (P less than 0.05). These data are consistent with the concept that increased postprandial plasma retinyl ester concentrations in older subjects are due to delayed plasma clearance of retinyl esters in triglyceride-rich lipoproteins of intestinal origin.

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Metadata

Authors
Krasinski, S. D., Cohn, J. S., Schaefer, E. J., & Russell, R. M.
Venue
Journal of Clinical Investigation
Published
1990-03-01
Volume
85
Issue
3
Pages
883-892
ISSN
0021-9738 (ISSN-L)
OpenAlex
W2016846453
Cited by
159
References
7
FWCI
8.81
Type
journal article
Language
en
Open access
bronze

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The paper
Krasinski, S. D., Cohn, J. S., Schaefer, E. J., & Russell, R. M. (1990). Postprandial plasma retinyl ester response is greater in older subjects compared with younger subjects. Evidence for delayed plasma clearance of intestinal lipoproteins. Journal of Clinical Investigation. https://doi.org/10.1172/jci114515

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.