Roles of insulin resistance and beta-cell dysfunction in dexamethasone-induced diabetes.

STUDIES ON ANTIBODY PRODUCTION

Coons, A. H., Leduc, E. H., & Connolly, J. M. (1955) · The Journal of Experimental Medicine · doi:10.1084/jem.102.1.49 · Cited by 1,560 · see citing works

Practical methods for biological morphometry

Weibel, E. R. (1979) · Academic Press eBooks · Cited by 1,502 · see citing works

Control of Cachectin (Tumor Necrosis Factor) Synthesis: Mechanisms of Endotoxin Resistance

Beutler, B., Krochin, N., Milsark, I. W., Luedke, C. E., & Cerami, A. (1986) · Science · doi:10.1126/science.3754653 · Cited by 1,268 · see citing works

[20] Isolation of RNA using guanidinium salts

MacDonald, R. J., Swift, G. H., Przybyla, A., & Chirgwin, J. M. (1987) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(87)52023-7 · Cited by 599 · see citing works

Insulin secretion in diabetes mellitus

Pfeifer, M. A., Halter, J. B., & Porte, D. (1981) · The American Journal of Medicine · doi:10.1016/0002-9343(81)90579-9 · Cited by 366 · see citing works

An Approach to the Prediction of Diabetes Mellitus by Modification of the Glucose Tolerance Test with Cortisone

Fajans, S. S., & Conn, J. W. (1954) · Diabetes · doi:10.2337/diab.3.4.296 · Cited by 277 · see citing works

Diabetic Hyperglycemia: Link to Impaired Glucose Transport in Pancreatic β Cells

Unger, R. H. (1991) · Science · doi:10.1126/science.2006409 · Cited by 263 · see citing works

Decreased Sensitivity of the Pancreatic Beta Cells to Glucose in Prediabetic and Diabetic Subjects: A Glucose Dose-Response Study

Cerasi, E., Luft, R., & Efendić, S. (1972) · Diabetes · doi:10.2337/diab.21.4.224 · Cited by 252 · see citing works

The high Km glucose transporter of islets of Langerhans is functionally similar to the low affinity transporter of liver and has an identical primary sequence.

Johnson, J. H., Newgard, C. B., Milburn, J. L., Lodish, H. F., & Thorens, B. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)39181-1 · Cited by 207 · see citing works

Arginine-stimulated acute phase of insulin and glucagon secretion in diabetic subjects.

Palmer, J. P., Benson, J. W., Walter, R. M., & Ensinck, J. W. (1976) · Journal of Clinical Investigation · doi:10.1172/jci108502 · Cited by 203 · see citing works

Underexpression of β Cell High K m Glucose Transporters in Noninsulin-Dependent Diabetes

Johnson, J. H., Ogawa, A., Chen, L., Orci, L., Newgard, C. B., Alam, T., & Unger, R. H. (1990) · Science · doi:10.1126/science.2237405 · Cited by 201 · see citing works

Reduced expression of the liver/beta-cell glucose transporter isoform in glucose-insensitive pancreatic beta cells of diabetic rats.

Thorens, B., Weir, G. C., Leahy, J. L., Lodish, H. F., & Bonner‐Weir, S. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.17.6492 · Cited by 158 · see citing works

Evidence that down-regulation of beta-cell glucose transporters in non-insulin-dependent diabetes may be the cause of diabetic hyperglycemia.

Orci, L., Ravazzola, M., Baetens, D., Inman, L. R., AMHERDT, M., Peterson, R. G., Newgard, C. B., Johnson, J. H., & Unger, R. H. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.24.9953 · Cited by 144 · see citing works

Regulation of beta-cell glucose transporter gene expression.

Chen, L., Alam, T., Johnson, J. H., Hughes, S., Newgard, C. B., & Unger, R. H. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.11.4088 · Cited by 108 · see citing works

[31] The in Vitro perfused pancreas

Grodsky, G. M., & Fanska, R. E. (1975) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(75)39033-2 · Cited by 88 · see citing works

Inhibition of Glucose Transport into Rat Islet Cells by Immunoglobulins from Patients with New-Onset Insulin-Dependent Diabetes Mellitus

Johnson, J. H., Crider, B. P., McCorkle, K., Alford, M., & Unger, R. H. (1990) · New England Journal of Medicine · doi:10.1056/nejm199003083221003 · Cited by 85 · see citing works

Loss of insulin response to glucose but not arginine during the development of autoimmune diabetes in BB/W rats: relationships to islet volume and glucose transport rate.

Tominaga, M., Komiya, I., Johnson, J. H., Inman, L. R., Alam, T., Moltz, J. H., Crider, B. P., Stefan, Y., Baetens, D., & McCorkle, K. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.24.9749 · Cited by 48 · see citing works

Levels of Plasma Insulin During Cortisone Glucose Tolerance Tests in “Nondiabetic” Relatives of Diabetic Patients: Implications of Diminished Insulin Secretory Reserve in Subclinical Diabetes

Rull, J. A., Conn, J. W., Floyd, J. C., & Fajans, S. S. (1970) · Diabetes · doi:10.2337/diab.19.1.1 · Cited by 48 · see citing works

Immunoreactive Glucagon (IRG) Responses to Intravenous Glucose in Prediabetes and Diabetes Among Pima Indians and Normal Caucasians

Aronoff, S. L., Bennett, P. H., & Unger, R. H. (1977) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-44-5-968 · Cited by 30 · see citing works

Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships.

Lee, Y., Hirose, H., Ohneda, M., Johnson, J. H., McGarry, J., & Unger, R. H. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.23.10878 · Cited by 832 · see citing works

Regulation of glucose homeostasis by glucocorticoids

Kuo, T., McQueen, A., Chen, T.-C., & Wang, J.-C. (2015) · Advances in Experimental Medicine and Biology · doi:10.1007/978-1-4939-2895-8_5 · Cited by 723 · see citing works

Lipid homeostasis, lipotoxicity and the metabolic syndrome

Unger, R. H., Clark, G. O., Scherer, P. E., & Orci, L. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2009.10.006 · Cited by 595 · see citing works

STZ Transport and Cytotoxicity: Specific Enhancement in GLUT2-Expressing Cells

Schnedl, W. J., Ferber, S., Johnson, J. H., & Newgard, C. B. (1994) · Diabetes · doi:10.2337/diab.43.11.1326 · Cited by 483 · see citing works

Novel insights into glucocorticoid‐mediated diabetogenic effects: towards expansion of therapeutic options?

Van Raalte, D. H., Ouwens, D. M., & Diamant, M. (2009) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2008.02067.x · Cited by 439 · see citing works

Human and rat beta cells differ in glucose transporter but not in glucokinase gene expression.

De Vos, A., Heimberg, H., Quartier, E., Huypens, P., Bouwens, L., Pipeleers, D., & Schuit, F. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118308 · Cited by 425 · see citing works

Direct glucocorticoid inhibition of insulin secretion. An in vitro study of dexamethasone effects in mouse islets.

Lambillotte, C., Gilon, P., & Henquin, J. C. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119175 · Cited by 419 · see citing works

11β-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice

Hermanowski‐Vosatka, A., Balkovec, J. M., Cheng, K., Chen, H. Y., Hernandez, M., Koo, G. C., LeGrand, C. B., Li, Z., Metzger, J. M., Mundt, S. S., et al. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20050119 · Cited by 361 · see citing works

A model of β-cell mass, insulin, and glucose kinetics: pathways to diabetes

TOPP, B., PROMISLOW, K., DEVRIES, G., MIURA, R. M., & FINEGOOD, D. T. (2000) · Journal of Theoretical Biology · doi:10.1006/jtbi.2000.2150 · Cited by 330 · see citing works

The multiple roles of life stress in metabolic disorders

Mika Kivimaki, B., Bartolomucci, A., & Kawachi, I. I. (2022) · Nature Reviews Endocrinology · doi:10.1038/s41574-022-00746-8 · Cited by 329 · see citing works

Pancreatic β-Cells in Obesity

Milburn, J. L., Hirose, H., Lee, Y. H., Nagasawa, Y., Ogawa, A., Ohneda, M., BeltrandelRio, H., Newgard, C. B., Johnson, J. H., & Unger, R. H. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.3.1295 · Cited by 269 · see citing works

Fresh insights into glucocorticoid-induced diabetes mellitus and new therapeutic directions

Li, J.-X., & Cummins, C. L. (2022) · Nature Reviews Endocrinology · doi:10.1038/s41574-022-00683-6 · Cited by 273 · see citing works

Glucocorticoid treatment and endocrine pancreas function: implications for glucose homeostasis, insulin resistance and diabetes

Rafacho, A., Ortsäter, H., Nadal, A., & Quesada, I. (2014) · Journal of Endocrinology · doi:10.1530/joe-14-0373 · Cited by 216 · see citing works

The Physiology of Cellular Liporegulation

Unger, R. H. (2003) · Annual Review of Physiology · doi:10.1146/annurev.physiol.65.092101.142622 · Cited by 202 · see citing works

Serum- and Glucocorticoid-Inducible Kinase 1 (SGK1) Mediates Glucocorticoid-Induced Inhibition of Insulin Secretion

Ullrich, S., Berchtold, S., Ranta, F., Seebohm, G., Henke, G., Lupescu, A., Mack, A. F., Chao, C., Su, J., Nitschke, R., et al. (2005) · Diabetes · doi:10.2337/diabetes.54.4.1090 · Cited by 175 · see citing works

Acute and 2-week exposure to prednisolone impair different aspects of β-cell function in healthy men

van Raalte, D. H., Nofrate, V., Bunck, M. C., van Iersel, T., Elassaiss Schaap, J., Nässander, U. K., Heine, R. J., Mari, A., Dokter, W. H. A., & Diamant, M. (2010) · European Journal of Endocrinology · doi:10.1530/eje-09-1034 · Cited by 170 · see citing works

Dexamethasone Induces Posttranslational Degradation of GLUT2 and Inhibition of Insulin Secretion in Isolated Pancreatic β Cells

Gremlich, S., Roduit, R., & Thorens, B. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.6.3216 · Cited by 155 · see citing works

Glucose transporters in pancreatic islets

Berger, C., & Zdzieblo, D. (2020) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-020-02383-4 · Cited by 119 · see citing works

Caloric restriction in obese pre-diabetic rats prevents beta-cell depletion, loss of beta-cell GLUT 2 and glucose incompetence

Ohneda, M., Inman, L. R., & Unger, R. H. (1995) · Diabetologia · doi:10.1007/bf00400091 · Cited by 110 · see citing works

Hypoglycemic Effect of Chinese Yam ( Dioscorea opposita rhizoma ) Polysaccharide in Different Structure and Molecular Weight

Ma, Q., Li, W., Gao, Q., & Zou, Y. (2017) · Journal of Food Science · doi:10.1111/1750-3841.13919 · Cited by 95 · see citing works

Impact of Glucocorticoid Excess on Glucose Tolerance: Clinical and Preclinical Evidence

Pasieka, A. M., & Rafacho, A. (2016) · Metabolites · doi:10.3390/metabo6030024 · Cited by 91 · see citing works

Functional Alterations in Endocrine Pancreas of Rats With Different Degrees of Dexamethasone-Induced Insulin Resistance

Rafacho, A., Giozzet, V. A. G., Boschero, A. C., & Bosqueiro, J. R. (2008) · Pancreas · doi:10.1097/mpa.0b013e31815ba826 · Cited by 87 · see citing works

Expression of GLUT-2 antisense RNA in beta cells of transgenic mice leads to diabetes.

Valera, A., Solanes, G., Fernández-Álvarez, J., Pujol, A., Ferrer, J. P., Asins, G., Gomis, R., & Bosch, F. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)61937-x · Cited by 85 · see citing works

Effects of glucocorticoids and exercise on pancreatic β‐cell function and diabetes development

Beaudry, J. L., & Riddell, M. C. (2012) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.2310 · Cited by 84 · see citing works

Deletion of the tissue response against alginate-pll capsules by temporary release of co-encapsulated steroids

Bünger, C. M., Tiefenbach, B., Jahnke, A., Gerlach, C., Freier, T., Schmitz, K., Hopt, U. T., Schareck, W. D., Klar, E., & de Vos, P. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.07.017 · Cited by 83 · see citing works

Glucocorticoids in Vivo Induce Both Insulin Hypersecretion and Enhanced Glucose Sensitivity of Stimulus-Secretion Coupling in Isolated Rat Islets

Rafacho, A., Marroquí, L., Taboga, S. R., Abrantes, J. L. F., Silveira, L. R., Boschero, A. C., Carneiro, E. M., Bosqueiro, J. R., Nadal, A., & Quesada, I. (2010) · Endocrinology · doi:10.1210/en.2009-0704 · Cited by 80 · see citing works

Potential Adverse Effects of Dexamethasone Therapy on COVID-19 Patients: Review and Recommendations

Chen, F., Hao, L., Zhu, S., Yang, X., Shi, W., Zheng, K., Wang, T., & Chen, H. (2021) · Infectious Diseases and Therapy · doi:10.1007/s40121-021-00500-z · Cited by 80 · see citing works

Dexamethasone-induced insulin resistance is associated with increased connexin 36 mRNA and protein expression in pancreatic rat islets

Rafacho, A., Roma, L. P., Taboga, S. R., Boschero, A. C., & Bosqueiro, J. R. (2007) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y07-037 · Cited by 71 · see citing works

Preclinical models of diabetic wound healing: A critical review

Sanapalli, B. K. R., Yele, V., Singh, M. K., Krishnamurthy, P. T., & Karri, V. V. S. R. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111946 · Cited by 77 · see citing works

Glucocorticoid induced insulin resistance impairs basal but not glucose entrained high-frequency insulin pulsatility in humans

Hollingdal, M., Juhl, C. B., Dall, R., Sturis, J., Veldhuis, J. D., Schmitz, O., & Pørksen, N. (2002) · Diabetologia · doi:10.1007/s125-002-8244-y · Cited by 67 · see citing works

Deletion of Pten in Pancreatic β-Cells Protects Against Deficient β-Cell Mass and Function in Mouse Models of Type 2 Diabetes

Wang, L., Liu, Y., Lu, S. Y., Nguyen, K.-T. T., Schroer, S. A., Suzuki, A., Mak, T. W., Gaisano, H. Y., & Woo, M. (2010) · Diabetes · doi:10.2337/db09-1805 · Cited by 65 · see citing works

Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion

Fine, N. H. F., Doig, C. L., Elhassan, Y. S., Vierra, N. C., Marchetti, P., Bugliani, M., Nano, R., Piemonti, L., Rutter, G. A., Jacobson, D. A., et al. (2018) · Diabetes · doi:10.2337/db16-1356 · Cited by 61 · see citing works

Glucocorticoid receptor in stromal cells is essential for glucocorticoid-mediated suppression of inflammation in arthritis

Koenen, M., Culemann, S., Vettorazzi, S., Caratti, G., Frappart, L., Baum, W., Krönke, G., Baschant, U., & Tuckermann, J. P. (2018) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2017-212762 · Cited by 59 · see citing works

Optimizing the therapeutic index of liposomal glucocorticoids in experimental arthritis

van den Hoven, J. M., Hofkens, W., Wauben, M. H. M., Wagenaar-Hilbers, J. P. A., Beijnen, J. H., Nuijen, B., Metselaar, J. M., & Storm, G. (2011) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2011.03.025 · Cited by 58 · see citing works

Increased pancreatic islet mass is accompanied by activation of the insulin receptor substrate‐2/serine‐threonine kinase pathway and augmented cyclin D2 protein levels in insulin‐resistant rats

Rafacho, A., Ribeiro, D. L., Boschero, A. C., Taboga, S. R., & Bosqueiro, J. R. (2008) · International Journal of Experimental Pathology · doi:10.1111/j.1365-2613.2008.00588.x · Cited by 57 · see citing works

Neuropeptide Y expression marks partially differentiated β cells in mice and humans

Rodnoi, P., Rajkumar, M. S., Moin, A. S. M., Georgia, S. K., Butler, A. E., & Dhawan, S. (2017) · JCI Insight · doi:10.1172/jci.insight.94005 · Cited by 55 · see citing works

Increased glucocorticoid sensitivity in islet beta-cells: effects on glucose 6-phosphatase, glucose cycling and insulin release

Ling, Z.-C., Khan, A. W., Delauny, F., Davani, B., Östenson, C., Gustafsson, J.-Α., Okret, S., Landau, B. R., & Efendić, S. (1998) · Diabetologia · doi:10.1007/s001250050961 · Cited by 52 · see citing works

Glucocorticoid-induced osteoporosis in the rat is prevented by the tyrosine phosphatase inhibitor, sodium orthovanadate

Hulley, P. A., Conradie, M., Langeveldt, C., & Hough, F. S. (2002) · Bone · doi:10.1016/s8756-3282(02)00807-4 · Cited by 52 · see citing works

Hypoglycaemic and anti-diabetic activity of stem bark extracts Erythrina indica in normal and alloxan-induced diabetic rats

Kumar, A., Nandakumar, K., Handral, M., Talwar, S., & Dhayabaran, D. (2011) · Saudi Pharmaceutical Journal · doi:10.1016/j.jsps.2010.10.001 · Cited by 48 · see citing works

GLUT-2 function in glucose-unresponsive beta cells of dexamethasone-induced diabetes in rats.

Ohneda, M., Johnson, J. H., Inman, L. R., & Unger, R. H. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116788 · Cited by 48 · see citing works

Insulin resistance, impaired glucose tolerance and non-insulin-dependent diabetes, pathologic mechanisms and treatment: Current status and therapeutic possibilities

Turner, N. C., & Clapham, J. C. (1998) · Birkhäuser Basel eBooks · doi:10.1007/978-3-0348-8845-5_2 · Cited by 46 · see citing works

Exogenous Glucocorticoids and a High-Fat Diet Cause Severe Hyperglycemia and Hyperinsulinemia and Limit Islet Glucose Responsiveness in Young Male Sprague-Dawley Rats

Beaudry, J. L., D'souza, A. M., Teich, T., Tsushima, R. G., & Riddell, M. C. (2013) · Endocrinology · doi:10.1210/en.2012-2114 · Cited by 44 · see citing works

Inhibition of 11β-HSD1 as a novel treatment for the metabolic syndrome: do glucocorticoids play a role?

Thieringer, R., & Hermanowski‐Vosatka, A. (2005) · Expert Review of Cardiovascular Therapy · doi:10.1586/14779072.3.5.911 · Cited by 43 · see citing works

GLUT2 surface expression and intracellular transport via the constitutive pathway in pancreatic beta cells and insulinoma: evidence for a block in trans-Golgi network exit by brefeldin A.

Thorens, B., Gérard, N., & Dériaz, N. (1993) · The Journal of Cell Biology · doi:10.1083/jcb.123.6.1687 · Cited by 43 · see citing works

Is GLUT2 required for glucose sensing?

Schuit, F. C. (1997) · Diabetologia · doi:10.1007/s001250050651 · Cited by 43 · see citing works

Glikokortykosteroidy a czynność komórek beta

Fichna, M., & Fichna, P. (2017) · Endokrynologia Polska · doi:10.5603/ep.2017.0060 · Cited by 42 · see citing works

Short-Term Curcumin Gavage Sensitizes Insulin Signaling in Dexamethasone-Treated C57BL/6 Mice

Tian, L., Zeng, K., Shao, W., Yang, B. B., Fantus, I. G., Weng, J., & Jin, T. (2015) · Journal of Nutrition · doi:10.3945/jn.115.216853 · Cited by 41 · see citing works

Identification of the human insulin negative regulatory element as a negative glucocorticoid response element

Goodman, P. A., Medina-Martínez, O., & Fernández‐Mejía, C. (1996) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(96)03830-0 · Cited by 41 · see citing works

A new mouse model of type 2 diabetes mellitus established through combination of high-fat diet, streptozotocin and glucocorticoid

Liu, S., Ma, L., Ren, X., Zhang, W., Shi, D., Huo, Y., Ba, Y., Bai, Y., & Cheng, N. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.120062 · Cited by 40 · see citing works

Experimental model of glucocorticoid-induced insulin resistance

Martínez, B. B., Pereira, A. C. C., Muzetti, J. H., Telles, F. D. P., Mundim, F. G. L., & Teixeira, M. A. (2016) · Acta Cirúrgica Brasileira · doi:10.1590/s0102-865020160100000001 · Cited by 40 · see citing works

Interaction of the Glucocorticoid Receptor and the Chicken Ovalbumin Upstream Promoter‐Transcription Factor II (COUP‐TFII): Implications for the Actions of Glucocorticoids on Glucose, Lipoprotein, and Xenobiotic Metabolism

Martino, M. U. D., Alesci, S., Chrousos, G. P., & Kino, T. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1321.006 · Cited by 40 · see citing works

Dexamethasone-induced insulin resistance and pancreatic adaptive response in aging rats are not modified by oral vanadyl sulfate treatment

Barbera, M., Fierabracci, V., Novelli, M., Bombara, M., Masiello, P., Bergamini, E., & Tata, V. D. (2001) · European Journal of Endocrinology · doi:10.1530/eje.0.1450799 · Cited by 40 · see citing works

Increased expression and activity of 11β-HSD-1 in diabetic islets and prevention with troglitazone

Duplomb, L., Lee, Y., Wang, M.-Y., Park, B. H., Takaishi, K., Agarwal, A. K., & Unger, R. H. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2003.11.160 · Cited by 39 · see citing works

Thyrotoxic periodic paralysis in a Hispanic man after the administration of prednisone

Liu, Z., Braverman, L. E., & Malabanan, A. (2006) · Endocrine Practice · doi:10.4158/ep.12.4.427 · Cited by 38 · see citing works

Transcription factor abnormalities as a cause of beta cell dysfunction in diabetes: a hypothesis

Weir, G. C., Sharma, A., Zangen, D., & Bonner‐Weir, S. (1997) · Acta Diabetologica · doi:10.1007/s005920050071 · Cited by 37 · see citing works

Antitumor activity and tumor localization of liposomal glucocorticoids in B16 melanoma-bearing mice

Banciu, M., Fens, M. H. A. M., Storm, G., & Schiffelers, R. M. (2008) · Journal of Controlled Release · doi:10.1016/j.jconrel.2008.01.008 · Cited by 37 · see citing works

Beta Cell Adaptation to Dexamethasone-Induced Insulin Resistance in Rats Involves Increased Glucose Responsiveness but not Glucose Effectiveness

Karlsson, S., stlund, B. R., Myrsén-Axcrona, U., Sundler, F., & Ahr�n, B. (2001) · Pancreas · doi:10.1097/00006676-200103000-00007 · Cited by 36 · see citing works

Molecular Basis of Pancreas Development and Function

Habener, J. F., & Hussain, M. A. (2001) · Endocrine updates · doi:10.1007/978-1-4615-1669-9 · Cited by 36 · see citing works

β-cell activity and hepatic insulin extraction following dexamethasone administration in healthy subjects

Kautzky-Willer, A., Thomaseth, K., Clodi, M., Ludvik, B., Waldhäusl, W., Prager, R., & Pacini, G. (1996) · Metabolism · doi:10.1016/s0026-0495(96)90224-3 · Cited by 35 · see citing works

Controlled Release of Dexamethasone from Organosilicone Constructs for Local Modulation of Inflammation in Islet Transplantation

Weaver, J. D., Song, Y. G., Yang, E. Y., Ricordi, C., Pileggi, A., Buchwald, P., & Stabler, C. L. (2015) · Tissue Engineering Part A · doi:10.1089/ten.tea.2014.0487 · Cited by 35 · see citing works

Amylin-insulin relationships in insulin resistance with and without diabetic hyperglycemia

Pieber, T. R., Stein, D. T., Ogawa, A., Alam, T., Ohneda, M., McCorkle, K., Chen, L., McGarry, J., & Unger, R. H. (1993) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1993.265.3.e446 · Cited by 35 · see citing works

Incidence of endocrine and exocrine insufficiency in patients with autoimmune pancreatitis at diagnosis and after treatment: a systematic review and meta-analysis

Lanzillotta, M., Tacelli, M., Falconi, M., Arcidiacono, P. G., Capurso, G., & Della‐Torre, E. (2022) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2022.03.014 · Cited by 34 · see citing works

Multiple epidural steroid injections and body mass index linked with occurrence of epidural lipomatosis: a case series

Jaimes, R., & Rocco, A. G. (2014) · BMC Anesthesiology · doi:10.1186/1471-2253-14-70 · Cited by 33 · see citing works

Dexamethasone treatment in vivo counteracts the functional pancreatic islet alterations caused by malnourishment in rats

Giozzet, V. A. G., Rafacho, A., Boschero, A. C., Carneiro, E. M., & Bosqueiro, J. R. (2008) · Metabolism · doi:10.1016/j.metabol.2007.12.004 · Cited by 33 · see citing works

Loss of GLUT2 glucose transporter expression in pancreatic beta cells from diabetic Chinese hamsters

J�rns, A., Tiedge, M., Lenzen, S., & Sickel, E. (1996) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/bf00200660 · Cited by 32 · see citing works

Optimal Elevation of β-Cell 11β-Hydroxysteroid Dehydrogenase Type 1 Is a Compensatory Mechanism That Prevents High-Fat Diet–Induced β-Cell Failure

Turban, S., Liu, X., Ramage, L. E., Webster, S. P., Walker, B. R., Dunbar, D. R., Mullins, J. J., Seckl, J. R., & Morton, N. M. (2012) · Diabetes · doi:10.2337/db11-1054 · Cited by 31 · see citing works

New functional aspects of the neuroendocrine marker secretagogin based on the characterization of its rat homolog

Gärtner, W., Vila, G., Daneva, T., Nabokikh, A., Koc-Saral, F., İlhan, A., Majdic, O., Luger, A., & Wagner, L. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00055.2007 · Cited by 31 · see citing works

Increase in PDX-1 Levels Suppresses Insulin Gene Expression in RIN 1046-38 Cells

Seijffers, R., Ben-David, O., Cohen, Y., Karasik, A., Berezin, M., Newgard, C. B., & Ferber, S. (1999) · Endocrinology · doi:10.1210/en.140.7.3311 · Cited by 31 · see citing works

Current Views of the Fat Cell as an Endocrine Cell: Lipotoxicity

Tchkonia, T., Corkey, B. E., & Kirkland, J. L. (2007) · Springer eBooks · doi:10.1007/978-0-387-32164-6_6 · Cited by 30 · see citing works

Insufficient adaptive capability of pancreatic endocrine function in dexamethasone-treated ageing rats

Novelli, M., Tata, V. D., Bombara, M., Lorenzini, A., Masini, M., Pollera, M., Bergamini, E., & Masiello, P. (1999) · Journal of Endocrinology · doi:10.1677/joe.0.1620425 · Cited by 30 · see citing works

Investigation of the mechanisms contributing to the compensatory increase in insulin secretion during dexamethasone-induced insulin resistance in rhesus macaques

Cummings, B. P., Bremer, A. A., Kieffer, T. J., D’Alessio, D. A., & Havel, P. J. (2012) · Journal of Endocrinology · doi:10.1530/joe-12-0459 · Cited by 29 · see citing works

Influence of topical dexamethasone applications on insulin, glucose, thyroid hormone and cortisol levels in dogs

Gottschalk, J., Einspanier, A., Ungemach, F. R., & Abraham, G. (2010) · Research in Veterinary Science · doi:10.1016/j.rvsc.2010.06.026 · Cited by 29 · see citing works

Serum thyroid hormone, insulin, glucose, triglycerides and protein concentrations in normal horses: Association with topical dexamethasone usage

Abraham, G., Allersmeier, M., Schusser, G. F., & Ungemach, F. R. (2010) · The Veterinary Journal · doi:10.1016/j.tvjl.2010.05.033 · Cited by 29 · see citing works

Mitogen-activated protein kinases and protein phosphatase 5 mediate glucocorticoid-induced cytotoxicity in pancreatic islets and β-cells

Fransson, L., Rosengren, V., Saha, T. K., Grankvist, N., Islam, T., Honkanen, R. E., Sjöholm, Å., & Ortsäter, H. (2013) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2013.12.010 · Cited by 28 · see citing works

Correction of Diabetic Hyperglycemia and Amelioration of Metabolic Anomalies by Minicircle DNA Mediated Glucose-Dependent Hepatic Insulin Production

Alam, T., Wai, P. Y., Held, D., Vakili, S. T. T., Forsberg, E., & Sollinger, H. W. (2013) · PLoS ONE · doi:10.1371/journal.pone.0067515 · Cited by 28 · see citing works

Sub-chronic stimulation of glucocorticoid receptor impairs and mineralocorticoid receptor protects cytosolic Ca2+ responses to glucose in pancreatic β-cells

Koizumi, M., & Yada, T. (2008) · Journal of Endocrinology · doi:10.1677/joe-07-0462 · Cited by 27 · see citing works

Insulin Regulation of Hepatic Glucose Transporter Protein Is Impaired in Chronic Pancreatitis

Andersen, D. K., Ruiz, C. L., & Burant, C. (1994) · Annals of Surgery · doi:10.1097/00000658-199406000-00011 · Cited by 27 · see citing works

Impaired Hepatocyte Glucose Transport Protein (GLUT2) Internalization in Chronic Pancreatitis

Nathan, J. D., Zdankiewicz, P. D., Wang, J., Spector, S. A., Aspelund, G., Jena, B. P., Seymour, N. E., Geibel, J. P., & Andersen, D. K. (2001) · Pancreas · doi:10.1097/00006676-200103000-00010 · Cited by 27 · see citing works

Age- and gender-related changes in glucose homeostasis in glucocorticoid-treated rats

dos Santos, C., Ferreira, F. B. D., Gonçalves-Neto, L. M., Taboga, S. R., Boschero, A. C., & Rafacho, A. (2014) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2014-0259 · Cited by 26 · see citing works

A Case of Nivolumab-Induced Acute-Onset Type 1 Diabetes Mellitus in Melanoma

Sakaguchi, C., Ashida, K., Yano, S., Ohe, K., Wada, N. A., Hasuzawa, N., Matsuda, Y., Sakamoto, S., Sakamoto, R., Uchi, H., et al. (2019) · Current Oncology · doi:10.3747/co.26.4130 · Cited by 25 · see citing works

Polysaccharide-Enriched Fraction from Amillariella Mellea Fruiting Body Improves Insulin Resistance

Yang, S., Meng, Y., Yan, J., Wang, N., Xue, Z., Zhang, H., & Fan, Y. (2018) · Molecules · doi:10.3390/molecules24010046 · Cited by 25 · see citing works

Nonimmunologic complications and gene polymorphisms of immunoregulatory cytokines in long-term renal transplants

Babel, N., Черепнев, Г. В., Kowalenko, A., Hörstrup, J. H., Volk, H., & Reinke, P. (2004) · Kidney International · doi:10.1111/j.1523-1755.2004.00749.x · Cited by 25 · see citing works

Cushing Syndrome, Hypercortisolism, and Glucose Homeostasis: A Review

DeFronzo, R. A., & Auchus, R. J. (2025) · Diabetes · doi:10.2337/db25-0120 · Cited by 30 · see citing works

MKP-1 Knockout Does not Prevent Glucocorticoid-Induced Bone Disease in Mice

Conradie, M., Cato, A. C. B., Ferris, W. F., de Wet, H., Horsch, K., & Hough, S. F. (2011) · Calcified Tissue International · doi:10.1007/s00223-011-9509-x · Cited by 23 · see citing works

Dexamethasone Induces Neuropeptide Y (NPY) Expression and Impairs Insulin Release in the Insulin-producing Cell Line RINm5F

Myrsén-Axcrona, U., Karlsson, S., Sundler, F., & Åhrén, B. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.16.10790 · Cited by 23 · see citing works

JTT‐608 restores impaired early insulin secretion in diabetic Goto‐Kakizaki rats

Ohta, T., Furukawa, N., Komuro, G., Yonemori, F., & Wakitani, K. (1999) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0702481 · Cited by 22 · see citing works

Enhanced adrenocortical activity as a contributing factor to diabetes in hyperandrogenic women

Buffington, C. K., Givens, J. R., & Kitabchi, A. E. (1994) · Metabolism · doi:10.1016/0026-0495(94)90200-3 · Cited by 21 · see citing works

G6PC2 Modulates the Effects of Dexamethasone on Fasting Blood Glucose and Glucose Tolerance

Boortz, K. A., Syring, K. E., Lee, R. A., Dai, C., Oeser, J. K., McGuinness, O. P., Wang, J.-C., & O’Brien, R. M. (2016) · Endocrinology · doi:10.1210/en.2016-1678 · Cited by 20 · see citing works

Risk factors and management of corticosteroid‐induced hyperglycaemia in paediatric acute lymphoblastic leukaemia

Gregoriou, K., Craigie, I., Gibson, B. E. S., Mason, A., & Shaikh, M. G. (2019) · Pediatric Blood & Cancer · doi:10.1002/pbc.28085 · Cited by 20 · see citing works

Regulation of Pancreatic β-Cell Function by the NPY System

Yang, C.-H., Onda, D.-A., Oakhill, J. S., Scott, J. W., Galić, S., & Loh, K. (2021) · Endocrinology · doi:10.1210/endocr/bqab070 · Cited by 19 · see citing works

Localized drug delivery graphene bioscaffolds for cotransplantation of islets and mesenchymal stem cells

Razavi, M., Wang, J., & Thakor, A. (2021) · Science Advances · doi:10.1126/sciadv.abf9221 · Cited by 19 · see citing works

In vivo glucose-stimulated amylin secretion is increased in nondiabetic patients with pancreatic cancer

̈kimattila, S. M., Hietaniemi, K., Kiviluoto, T. A., Timonen, T., & rvinen, H. Y.-J. (2001) · Metabolism · doi:10.1053/meta.2001.25801 · Cited by 18 · see citing works

Acute impairment of insulin signalling by dexamethasone in primary cultured rat skeletal myocytes

Brown, P. D., Badal, S. A. M., Morrison, S., & Ragoobirsingh, D. (2006) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-006-9344-y · Cited by 17 · see citing works

Glibenclamide but not other sulphonylureas stimulates release of neuropeptide Y from perifused rat islets and hamster insulinoma cells

Kulkarni, R., Wang, Z., Wang, R., Smith, D. M., Ghatei, M. A., & Bloom, S. R. (2000) · Journal of Endocrinology · doi:10.1677/joe.0.1650509 · Cited by 17 · see citing works

Fat feeding potentiates the diabetogenic effect of dexamethasone in Wistar rats

Sivabalan, S., Renuka, S., & Menon, V. P. (2008) · International Archives of Medicine · doi:10.1186/1755-7682-1-7 · Cited by 17 · see citing works

Adaptive response of rat pancreatic β-cells to insulin resistance induced by monocrotophos: Biochemical evidence

Nagaraju, R., & Rajini, P. S. (2016) · Pesticide Biochemistry and Physiology · doi:10.1016/j.pestbp.2016.04.009 · Cited by 16 · see citing works

β-Cell stimulus–secretion coupling defects in rodent models of obesity

Chan, C. B. (1995) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y95-197 · Cited by 16 · see citing works

cAMP prevents the glucose-mediated stimulation of GLUT2 gene transcription in hepatocytes

Rencurel, F., Waeber, G., Bonny, C., Antoine, B., MAULARD, P., Girard, J. R., & Leturque, A. (1997) · Biochemical Journal · doi:10.1042/bj3220441 · Cited by 16 · see citing works

Cytoprotective effect of genistein against dexamethasone-induced pancreatic β-cell apoptosis

Suksri, K., Semprasert, N., Limjindaporn, T., Yenchitsomanus, P., Kooptiwoot, S., & Kooptiwut, S. (2022) · Scientific Reports · doi:10.1038/s41598-022-17372-z · Cited by 15 · see citing works

Irreversible loss of normal beta-cell regulation by glucose in neonatally streptozotocin diabetic rats

Inoue, K., Ćetković-Cvrlje, M., Eizirik, D. L., & Grill, V. (1994) · Diabetologia · doi:10.1007/bf00408470 · Cited by 15 · see citing works

GLUT-2 function in glucose-unresponsive beta cells of dexamethasone-induced diabetes in rats.

Ohneda, M., Johnson, J. H., Inman, L. R., & Unger, R. H. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116788 · Cited by 48 · see citing works

Beta Cell Adaptation to Dexamethasone-Induced Insulin Resistance in Rats Involves Increased Glucose Responsiveness but not Glucose Effectiveness

Karlsson, S., stlund, B. R., Myrsén-Axcrona, U., Sundler, F., & Ahr�n, B. (2001) · Pancreas · doi:10.1097/00006676-200103000-00007 · Cited by 36 · see citing works

Dexamethasone Induces Posttranslational Degradation of GLUT2 and Inhibition of Insulin Secretion in Isolated Pancreatic β Cells

Gremlich, S., Roduit, R., & Thorens, B. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.6.3216 · Cited by 155 · see citing works

Increased pancreatic islet mass is accompanied by activation of the insulin receptor substrate‐2/serine‐threonine kinase pathway and augmented cyclin D2 protein levels in insulin‐resistant rats

Rafacho, A., Ribeiro, D. L., Boschero, A. C., Taboga, S. R., & Bosqueiro, J. R. (2008) · International Journal of Experimental Pathology · doi:10.1111/j.1365-2613.2008.00588.x · Cited by 57 · see citing works

Dexamethasone-induced insulin resistance enhances B cell responsiveness to glucose level in normal men

Beard, J. C., Halter, J. B., Best, J. D., Pfeifer, M. A., & Porte, D. (1984) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1984.247.5.e592 · Cited by 109 · see citing works