Total and resting energy expenditure in obese women reduced to ideal body weight.

Amatruda, J M; Statt, M C; Welle, S L

doi:10.1172/jci116695

Cited by 117Regulation of Appetite and ObesityObesity, Physical Activity, DietEating Disorders and Behaviors

Total and resting energy expenditure in obese women reduced to ideal body weight.

Open access

Amatruda, J M, Statt, M C, Welle, S L·1993·Journal of Clinical Investigation

DOI 10.1172/jci116695PMC PMC288263

Open this paper in CoChat — free account Open PDF

Abstract

Obesity could be due to excess energy intake or decreased energy expenditure (EE). To evaluate this, we studied 18 obese females (148 +/- 8% of ideal body weight [IBW], mean +/- SD) before and after achieving and stabilizing at IBW for at least 2 mo and a control group of 14 never obese females (< 110% of IBW or < 30% fat). In the obese, reduced obese, and never obese groups, the percent of body fat was 41 +/- 4%, 27 +/- 4%, and 25 +/- 3%; total energy expenditure (TEE) was 2704 +/- 449, 2473 +/- 495, and 2259 +/- 192 kcal/24 h; while resting metabolic rate was 1496 +/- 169, 1317 +/- 159, and 1341 +/- 103 kcal/24 h, respectively. 15 obese subjects who withdrew from the study had a mean initial body composition and EE similar to the subjects who were successful in achieving IBW. In 10 subjects followed for at least one year after stabilizing at IBW there was no significant relationship between the deviation from predicted TEE at IBW and weight regain. These studies indicate that, in a genetically heterogeneous female population, neither the propensity to become obese nor to maintain the obese state are due to an inherent metabolic abnormality characterized by a low EE.

Integrity signals

Registry

Crossref · 10.1172/jci116695

Cites

37 of 37 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Obese subjects who lose weight by dieting experience a decrease in body mass of multiple tissues and an obligate decrease in energy expenditure.
“First, obese subjects who lose weight by dieting experience a decrease in body mass of multiple tissues and an obligate decrease in energy expenditure (16,17).”
From Long-term Effects of Large-volume Liposuction on Metabolic Risk Factors for Coronary Heart Disease (2008) · cites this paper as [17]

Impact of Informing Overweight Individuals about the Role of Genetics in Obesity: An Online Experimental Study
Lippa, N. C., & Sanderson, S. C. (2013) · Human Heredity · doi:10.1159/000353712 · Cited by 6,093 · see citing works
BMDP Statistical Software 1981.
Bubolz, T. A., & Dixon, W. J. (1984) · Journal of the American Statistical Association · doi:10.2307/2288308 · Cited by 5,246 · see citing works
An Adoption Study of Human Obesity
Stunkard, A. J., Sørensen, T. I. A., Hanis, C. L., Teasdale, T. W., Chakraborty, R., Schull, W. J., & D, F. S. M. (1986) · New England Journal of Medicine · doi:10.1056/nejm198601233140401 · Cited by 1,301 · see citing works
The Body-Mass Index of Twins Who Have Been Reared Apart
Stunkard, A. J., Harris, J. R., Pedersen, N. L., & McClearn, G. E. (1990) · New England Journal of Medicine · doi:10.1056/nejm199005243222102 · Cited by 1,286 · see citing works
The Response to Long-Term Overfeeding in Identical Twins
Bouchard, C., Tremblay, A., Després, J.-P., Nadeau, A., Lupien, P. J., Thériault, G., Dussault, J., Moorjani, S., Pinault, S., & Fournier, G. (1990) · New England Journal of Medicine · doi:10.1056/nejm199005243222101 · Cited by 1,278 · see citing works
Reduced Rate of Energy Expenditure as a Risk Factor for Body-Weight Gain
Ravussin, E., Lillioja, S., Knowler, W. C., Christin, L., Freymond, D., Abbott, W. G. H., Boyce, V., Howard, B. V., & Bogardus, C. (1988) · New England Journal of Medicine · doi:10.1056/nejm198802253180802 · Cited by 1,215 · see citing works
Health Implications of Overweight and Obesity in the United States
Itallie, T. B. V. (1985) · Annals of Internal Medicine · doi:10.7326/0003-4819-103-6-983 · Cited by 902 · see citing works
Energy expenditure by doubly labeled water: validation in humans and proposed calculation
Schoeller, D. A., Ravussin, É., Schutz, Y., Acheson, K. J., Baertschi, P., & Jéquier, E. (1986) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1986.250.5.r823 · Cited by 683 · see citing works
Measurement of Energy Expenditure in Free-Living Humans by Using Doubly Labeled Water
Schoeller, D. A. (1988) · Journal of Nutrition · doi:10.1093/jn/118.11.1278 · Cited by 602 · see citing works
Familial Dependence of the Resting Metabolic Rate
Bogardus, C., Lillioja, S., Ravussin, E., Abbott, W., Zawadzki, J. K., Young, A., Knowler, W. C., Jacobowitz, R., & Moll, P. P. (1986) · New England Journal of Medicine · doi:10.1056/nejm198607103150205 · Cited by 398 · see citing works
Complications of Obesity
Bray, G. A. (1985) · Annals of Internal Medicine · doi:10.7326/0003-4819-103-6-1052 · Cited by 384 · see citing works
Energy Expenditure and Intake in Infants Born to Lean and Overweight Mothers
Roberts, S. B., Savage, J., Coward, W. A., Chew, B., & Lucas, A. (1988) · New England Journal of Medicine · doi:10.1056/nejm198802253180801 · Cited by 380 · see citing works
Diminished energy requirements in reduced-obese patients
Leibel, R. L., & Hirsch, J. (1984) · Metabolism · doi:10.1016/0026-0495(84)90130-6 · Cited by 270 · see citing works
Energy expenditure and postprandial thermogenesis in obese women before and after weight loss
Bessard, T., Schutz, Y., & Jéquier, E. (1983) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/38.5.680 · Cited by 257 · see citing works
Energy expenditure before and during energy restriction in obese patients
Ravussin, É., Burnand, B., Schutz, Y., & Jéquier, E. (1985) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/41.4.753 · Cited by 211 · see citing works
Current understanding of the etiology of obesity: genetic and nongenetic factors
Bouchard, C. (1991) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/53.6.1561s · Cited by 208 · see citing works
Genetic effect in resting and exercise metabolic rates
Bouchard, C., Tremblay, A., Nadeau, A., Després, J., Thériault, G., Boulay, M. R., Lortie, G., Leblanc, C. P., & Fournier, G. (1989) · Metabolism · doi:10.1016/0026-0495(89)90126-1 · Cited by 205 · see citing works
Energy expenditure from doubly labeled water: some fundamental considerations in humans
Schoeller, D. (1983) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/38.6.999 · Cited by 193 · see citing works
Relationship of resting metabolic rate to body composition and protein turnover
Welle, S. L., & Nair, K. S. (1990) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1990.258.6.e990 · Cited by 185 · see citing works
Self-citation
Energy expenditure in small children of obese and non-obese parents
Griffiths, M., & Payne, P. (1976) · Nature · doi:10.1038/260698a0 · Cited by 164 · see citing works
Weight loss leads to a marked decrease in nonresting energy expenditure in ambulatory human subjects
Weigle, D. S., Sande, K. J., Iverius, P., Monsen, E. R., & Brunzell, J. D. (1988) · Metabolism · doi:10.1016/0026-0495(88)90149-7 · Cited by 138 · see citing works
Sustained depression of the resting metabolic rate after massive weight loss
Elliot, D. L., Goldberg, L., Kuehl, K. S., & Bennett, W. M. (1989) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/49.1.93 · Cited by 131 · see citing works
The daily metabolic rate of the post-obese and the lean
Geissler, C. A., Miller, D. S., & Shah, M. (1987) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/45.5.914 · Cited by 121 · see citing works
Body composition in adopted and biological siblings.
Bouchard, C., Savard, R., Jp, D., Tremblay, A., & Leblanc, C. P. (1985) · PubMed · Cited by 113 · see citing works
Energy expenditure under free-living conditions in normal-weight and overweight women
Welle, S. L., Forbes, G., Statt, M., Barnard, R. R., & Amatruda, J. (1992) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/55.1.14 · Cited by 94 · see citing works
Self-citation
RESISTANCE TO SLIMMING ADAPTATION OR ILLUSION ?
Miller, D. S., & Parsonage, S. (1975) · The Lancet · doi:10.1016/s0140-6736(75)92437-x · Cited by 92 · see citing works
Adaptation of energy metabolism of overweight women to low-energy Intake, studied with whole-body calorimeters
de Boer, J., van Es, A. J. H., Roovers, L., Raaij, J. V., & HAUTVAST, J. G. A. J. (1986) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/44.5.585 · Cited by 83 · see citing works
Effects of Body Size on Potassium-40 Measurement in the Whole Body Counter (Tilt-chair Technique)
Forbes, G. B., Schultz, F., Cafarelli, C., & Amirhakimi, G. H. (1968) · Health Physics · doi:10.1097/00004032-196811000-00004 · Cited by 77 · see citing works
Metabolic and health complications of obesity
(1990) · Disease-a-Month · doi:10.1016/0011-5029(90)90015-j · Cited by 74 · see citing works
Prediction of energy requirements of obese patients after massive weight loss.
Doré, C. J., Hesp, R., Wilkins, D., & Garrow, J. S. (1982) · PubMed · Cited by 70 · see citing works
Resting Metabolic Rates of Obese Women after Rapid Weight Loss*
Welle, S. L., Amatruda, J. M., Forbes, G. B., & Lockwood, D. H. (1984) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-59-1-41 · Cited by 60 · see citing works
Self-citation
24-hour energy expenditure and sympathetic activity in postobese women consuming a high-carbohydrate diet
Astrup, A. V., Buemann, B., Christensen, N. J., & Madsen, J. (1992) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1992.262.3.e282 · Cited by 51 · see citing works
Childhood onset (age less than 10) obesity has high familial risk.
Price, R. A., Stunkard, A. J., Ness, R. B., Wadden, T. A., Heshka, S., Kanders, B. S., & Cormillot, A. (1990) · PubMed · Cited by 30 · see citing works
Lower metabolic rates of post-obese versus lean women: thermogenesis, basal metabolic rate and genetics.
Shah, M., Miller, D. S., & Geissler, C. A. (1988) · PubMed · Cited by 29 · see citing works
Two-point vs multipoint sample collection for the analysis of energy expenditure by use of the doubly labeled water method
Welle, S. L. (1990) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/52.6.1134 · Cited by 27 · see citing works
Self-citation
Energy metabolism of overweight women 1 mo and 1 y after an 8-wk slimming period
de Groot, C. P. G. M., van Es, A., van Raaij, J., Vogt, J. E., & Hautvast, J. (1990) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/51.4.578 · Cited by 26 · see citing works
Dietary recommendations after weight loss: how to avoid relapse of obesity
James, W. P. T., Lean, M. E. J., & McNeill, G. (1987) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/45.5.1135 · Cited by 17 · see citing works

Flagged first, then by citations

1 of the 38 references couldn’t be matched to a known paper.

Sorted by citations

Changes in Energy Expenditure Resulting from Altered Body Weight
Leibel, R. L., Rosenbaum, M., & Hirsch, J. (1995) · New England Journal of Medicine · doi:10.1056/nejm199503093321001 · Cited by 2,012 · see citing works
The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase
Kern, P. A., Saghizadeh, M., Ong, J. M., Bosch, R. J., Deem, R., & Simsolo, R. B. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117899 · Cited by 1,305 · see citing works
Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss
Kelley, D. E., Goodpaster, B., Wing, R. R., & Simoneau, J.-A. (1999) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1999.277.6.e1130 · Cited by 1,096 · see citing works
Tumor Necrosis Factor- in Sera of Obese Patients: Fall with Weight Loss
Dandona, P. (1998) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.83.8.2907 · Cited by 176 · see citing works
Long-term persistence of adaptive thermogenesis in subjects who have maintained a reduced body weight
Rosenbaum, M., Hirsch, J., Gallagher, D. A., & Leibel, R. L. (2008) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/88.4.906 · Cited by 444 · see citing works
Nonsurgical Factors That Influence the Outcome of Bariatric Surgery: A Review
Hsu, L. K. G., Benotti, P. N., Dwyer, J., Roberts, S. B., Saltzman, E., Shikora, S., Rolls, B. J., & Rand, W. (1998) · Psychosomatic Medicine · doi:10.1097/00006842-199805000-00021 · Cited by 440 · see citing works
Energy metabolism, fuel selection and body weight regulation
Galgani, J. E., & Ravussin, É. (2008) · International Journal of Obesity · doi:10.1038/ijo.2008.246 · Cited by 372 · see citing works
Adaptive thermogenesis in humans
Rosenbaum, M., & Leibel, R. L. (2010) · International Journal of Obesity · doi:10.1038/ijo.2010.184 · Cited by 349 · see citing works
Meta-analysis of resting metabolic rate in formerly obese subjects
Astrup, A., Gøtzsche, P. C., van de Werken, K., Ranneries, C., Toubro, S., Raben, A., & Buemann, B. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.6.1117 · Cited by 296 · see citing works
AGA technical review on obesity
Klein, S., Wadden, T., & Sugerman, H. J. (2002) · Gastroenterology · doi:10.1053/gast.2002.35514 · Cited by 274 · see citing works
Behavioral Strategies of Individuals Who Have Maintained Long‐Term Weight Losses
McGuire, M. T., Wing, R. R., Klem, M. L., & Hillf, J. O. (1999) · Obesity Research · doi:10.1002/j.1550-8528.1999.tb00416.x · Cited by 263 · see citing works
Why do obese patients not lose more weight when treated with low-calorie diets? A mechanistic perspective
Heymsfield, S. B., Harp, J. B., Reitman, M. L., Beetsch, J. W., Schoeller, D. A., Erondu, N., & Pietrobelli, A. (2007) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/85.2.346 · Cited by 229 · see citing works
Do adaptive changes in metabolic rate favor weight regain in weight-reduced individuals? An examination of the set-point theory
Weinsier, R. L., Nagy, T. R., Hunter, G. R., Darnell, B. E., Hensrud, D. D., & Weiss, H. L. (2000) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/72.5.1088 · Cited by 208 · see citing works
Long-term changes in energy expenditure and body composition after massive weight loss induced by gastric bypass surgery
Das, S. K., Roberts, S. B., Crory, M. A. M., Hsu, L. G., Shikora, S. A., Kehayias, J. J., Dallal, G. E., & Saltzman, E. J. (2003) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/78.1.22 · Cited by 210 · see citing works
Energy expenditure and free-living physical activity in black and white women: comparison before and after weight loss
Weinsier, R. L., Hunter, G. R., Zuckerman, P. A., Redden, D. T., Darnell, B. E., Larson, D. E., Newcomer, B. R., & Goran, M. I. (2000) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/71.5.1138 · Cited by 178 · see citing works
Resistance Training Conserves Fat-Free Mass and Resting Energy Expenditure Following Weight Loss
Hunter, G. R., Byrne, N. M., Sirikul, B., Fernández, J. R., Zuckerman, P. A., Darnell, B. E., & Gower, B. A. (2008) · Obesity · doi:10.1038/oby.2008.38 · Cited by 173 · see citing works
Metabolic predictors of obesity. Contribution of resting energy expenditure, thermic effect of food, and fuel utilization to four-year weight gain of post-obese and never-obese women.
Weinsier, R. L., Nelson, K. M., Hensrud, D. D., Darnell, B. E., Hunter, G. R., & Schutz, Y. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117807 · Cited by 170 · see citing works
Enhanced metabolic efficiency contributes to weight regain after weight loss in obesity-prone rats
MacLean, P. S., HIGGINS, J. A., Johnson, G. C., Fleming‐Elder, B. K., Donahoo, W. T., Melanson, E. L., & Hill, J. O. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00463.2004 · Cited by 162 · see citing works
Energy Expenditure, Fat Oxidation, and Body Weight Regulation: A Study of Metabolic Adaptation to Long- Term Weight Change
Weyer, C., Pratley, R. E., Salbe, A. D., Bogardus, C., Ravussin, E., & Tataranni, P. A. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.3.6447 · Cited by 158 · see citing works
Body Composition and Metabolic Changes following Bariatric Surgery: Effects on Fat Mass, Lean Mass and Basal Metabolic Rate: Six Months to One-Year Follow-up
Carey, D., Pliego, G. J., & Raymond, R. L. (2006) · Obesity Surgery · doi:10.1381/096089206779319347 · Cited by 148 · see citing works
Energy expenditure in adults living in developing compared with industrialized countries: a meta-analysis of doubly labeled water studies
Dugas, L. R., Harders, R., Merrill, S., Ebersole, K., Shoham, D. A., Rush, E. C., Assah, F. K., Forrester, T., Durazo-Arvizu, R. A., & Luke, A. (2011) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.007278 · Cited by 138 · see citing works
Energy metabolism in weight-stable postobese individuals
Larson, D., Ferraro, R., Robertson, D. S., & Ravussin, É. (1995) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/62.4.735 · Cited by 137 · see citing works
Relative changes in resting energy expenditure during weight loss: a systematic review
Schwartz, A., & Doucet, É. (2010) · Obesity Reviews · doi:10.1111/j.1467-789x.2009.00654.x · Cited by 132 · see citing works
Effect of a high-protein, energy-restricted diet on weight loss and energy expenditure after weight stabilization in hyperinsulinemic subjects
Luscombe, N. D., Clifton, P. M., Noakes, M., Farnsworth, E., & Wittert, G. (2003) · International Journal of Obesity · doi:10.1038/sj.ijo.0802270 · Cited by 124 · see citing works
Effect of weight loss and regain on adipose tissue distribution, composition of lean mass and resting energy expenditure in young overweight and obese adults
Bosy‐Westphal, A., Schautz, B., Lagerpusch, M., Pourhassan, M., Braun, W., Goele, K., Heller, M., Glüer, C.-C., & Müller, M. (2013) · International Journal of Obesity · doi:10.1038/ijo.2013.1 · Cited by 123 · see citing works
The Role of Energy Expenditure in Energy Regulation: Findings from a Decade of Research
Saltzman, E. J., & Roberts, S. B. (2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.1995.tb01554.x · Cited by 122 · see citing works
Modeling weight-loss maintenance to help prevent body weight regain
Hall, K. D., & Jordan, P. N. (2008) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26333 · Cited by 110 · see citing works
Long-term Effects of Large-volume Liposuction on Metabolic Risk Factors for Coronary Heart Disease
Mohammed, B. S., Cohen, S., Reeds, D., Young, V. L., & Klein, S. (2008) · Obesity · doi:10.1038/oby.2008.418 · Cited by 108 · see citing works
A Missing Link in Body Weight Homeostasis: The Catabolic Signal of the Overfed State
Ravussin, Y., Leibel, R. L., & Ferrante, A. W. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2014.09.002 · Cited by 108 · see citing works
Resting energy expenditure in reduced-obese subjects in the National Weight Control Registry
Wyatt, H. R., Grunwald, G. K., Seagle, H. M., Klem, M. L., McGuire, M. T., Wing, R. R., & Hill, J. O. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.6.1189 · Cited by 108 · see citing works
Prevention of obesity – is it possible?
Müller, M. J., Mast, M., Asbeck, I., Langnäse, K., & Grund, A. (2001) · Obesity Reviews · doi:10.1046/j.1467-789x.2001.00012.x · Cited by 103 · see citing works
Metabolic adjustments with the development, treatment, and recurrence of obesity in obesity-prone rats
MacLean, P. S., HIGGINS, J. A., Johnson, G. C., Fleming‐Elder, B. K., Peters, J. C., & Hill, J. O. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00010.2004 · Cited by 100 · see citing works
Metabolic Determinants of Weight Gain in Humans
Piaggi, P. (2019) · Obesity · doi:10.1002/oby.22456 · Cited by 96 · see citing works
Models of energy homeostasis in response to maintenance of reduced body weight
Rosenbaum, M., & Leibel, R. L. (2016) · Obesity · doi:10.1002/oby.21559 · Cited by 95 · see citing works
Validation of energy intake measurements determined from observer-recorded food records and recall methods compared with the doubly labeled water method in overweight and obese individuals
Hise, M. E., Sullivan, D. K., JACOBSEN, D. J., Johnson, S. L., & Donnelly, J. E. (2002) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/75.2.263 · Cited by 78 · see citing works
The energy balance equation: looking back and looking forward are two very different views
Schoeller, D. A. (2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.2009.00197.x · Cited by 79 · see citing works
Low resting metabolic rate in subjects predisposed to obesity: a role for thyroid status
Astrup, A. V., Buemann, B., Toubro, S., Ranneries, C., & Raben, A. (1996) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/63.6.879 · Cited by 77 · see citing works
Energy expenditure in the etiology of human obesity: spendthrift and thrifty metabolic phenotypes and energy-sensing mechanisms
Piaggi, P., Vinales, K. L., Basolo, A., Santini, F., & Krakoff, J. A. (2017) · Journal of Endocrinological Investigation · doi:10.1007/s40618-017-0732-9 · Cited by 76 · see citing works
Body Composition and Metabolic Changes Following Bariatric Surgery: Effects on Fat Mass, Lean Mass and Basal Metabolic Rate
Carey, D., Pliego, G. J., Raymond, R. L., & Skau, K. B. (2006) · Obesity Surgery · doi:10.1381/096089206776327378 · Cited by 75 · see citing works
Physical activity and energy requirements
Hill, J., Melby, C. L., Johnson, S., & Peters, J. (1995) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/62.5.1059s · Cited by 68 · see citing works
Short-term effects of weight loss with or without low-intensity exercise training on fat metabolism in obese men
van Aggel‐Leijssen, D. P., Saris, W. H. M., Hul, G. B. J., & van Baak, M. A. (2001) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/73.3.523 · Cited by 66 · see citing works
Resting Energy Expenditure: From Cellular to Whole‐Body Level, a Mechanistic Historical Perspective
Heymsfield, S. B., Smith, B., Dahle, J. H., Kennedy, S., Fearnbach, N., Thomas, D. M., Bosy‐Westphal, A., & Müller, M. J. (2021) · Obesity · doi:10.1002/oby.23090 · Cited by 65 · see citing works
Metabolic adaptation is an illusion, only present when participants are in negative energy balance
Martins, C., Roekenes, J., Salamati, S., Gower, B. A., & Hunter, G. R. (2020) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqaa220 · Cited by 65 · see citing works
Postgastroplasty recovery of ideal body weight normalizes glucose and insulin metabolism in obese women
Letiexhe, M. R., Scheen, A. J., Gèrard, P. L., Desaive, C., & Lefèbvre, P. J. (1995) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.80.2.7852491 · Cited by 62 · see citing works
Effect of Diet Composition and Weight Loss on Resting Energy Expenditure in the POUNDS LOST Study
de Jonge, L., Bray, G. A., Smith, S. R., Ryan, D. H., de Souza, R. J., Loria, C. M., Champagne, C. M., Williamson, D. A., & Sacks, F. M. (2012) · Obesity · doi:10.1038/oby.2012.127 · Cited by 58 · see citing works
Variation in Total Energy Expenditure in Humans
Goran, M. I. (1995) · Obesity Research · doi:10.1002/j.1550-8528.1995.tb00008.x · Cited by 54 · see citing works
Low Resting and Sleeping Energy Expenditure and Fat Use Do Not Contribute to Obesity in Women
Weinsier, R. L., Hunter, G. R., Zuckerman, P. A., & Darnell, B. E. (2003) · Obesity Research · doi:10.1038/oby.2003.129 · Cited by 52 · see citing works
Holiday weight management by successful weight losers and normal weight individuals.
Phelan, S., Wing, R. R., Raynor, H. A., Dibello, J., Nedeau, K., & Peng, W. (2008) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.76.3.442 · Cited by 50 · see citing works
Changes in Energy Expenditure Resulting from Altered Body Weight
(1995) · New England Journal of Medicine · doi:10.1056/nejm199508103330628 · Cited by 50 · see citing works
The obesity treatment dilemma: Why dieting is both the answer and the problem? A mechanistic overview
Monnier, L., Schlienger, J.-L., Colette, C., & Bonnet, F. (2021) · Diabetes & Metabolism · doi:10.1016/j.diabet.2020.09.002 · Cited by 47 · see citing works
Weight loss maintenance: Determinants of long-term success
Sarlio‐Lähteenkorva, S., & Rissanen, A. (1998) · Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity · doi:10.1007/bf03340000 · Cited by 46 · see citing works
Effect of diet composition on energy expenditure during weight loss: the POUNDS LOST Study
Bray, G. A., Smith, S. R., de Jonge, L., de Souza, R. J., Rood, J. C., Champagne, C. M., Laranjo, N., Carey, V. J., Obarzanek, E., Loria, C. M., et al. (2011) · International Journal of Obesity · doi:10.1038/ijo.2011.173 · Cited by 44 · see citing works
Reduction of sleeping metabolic rate after vertical banded gastroplasty
van Gemert, W. G., Westerterp, K. R., Greve, J.-W. M., & Soeters, P. B. (1998) · International Journal of Obesity · doi:10.1038/sj.ijo.0800592 · Cited by 42 · see citing works
Twenty-four-hour energy and nutrient balance in weight stable postobese patients after biliopancreatic diversion
Tataranni, P., Mingrone, G., Raguso, C., Gaetano, A. D., Tacchino, R. M., Castagneto, M., & Av, G. (1996) · Nutrition · doi:10.1016/s0899-9007(96)90849-7 · Cited by 42 · see citing works
Influence of dietary supplementation with l-carnitine on metabolic rate, fatty acid oxidation, body condition, and weight loss in overweight cats
Warner, K. L., Randolph, J. F., Sunvold, G. D., & Vickers, J. R. (2012) · American Journal of Veterinary Research · doi:10.2460/ajvr.73.7.1002 · Cited by 41 · see citing works
The effects of short-term overfeeding on energy expenditure and nutrient oxidation in obesity-prone and obesity-resistant individuals
Schmidt, S. L., Kealey, E. H., Horton, T. J., Vonkaenel, S., & Bessesen, D. H. (2012) · International Journal of Obesity · doi:10.1038/ijo.2012.202 · Cited by 40 · see citing works
Effects of carbohydrate quantity and glycemic index on resting metabolic rate and body composition during weight loss
Karl, J. P., Roberts, S. B., Schaefer, E. J., Gleason, J. A., Fuss, P., Rasmussen, H., Saltzman, E. J., & Das, S. K. (2015) · Obesity · doi:10.1002/oby.21268 · Cited by 39 · see citing works
Predictors of weight gain: the biological‐behavioural debate
FILOZOF, C. M., & González, C. D. (2000) · Obesity Reviews · doi:10.1046/j.1467-789x.2000.00005.x · Cited by 39 · see citing works
Differential effect of insulin on whole-body proteolysis and glucose metabolism in normal-weight, obese, and reduced-obese women
Welle, S. L., Statt, M., Barnard, R., & Amatruda, J. M. (1994) · Metabolism · doi:10.1016/0026-0495(94)90073-6 · Cited by 37 · see citing works
Self-citation
Sympathetic nervous system response to intake
Welle, S. L. (1995) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/62.5.1118s · Cited by 37 · see citing works
Self-citation
Energy requirements across the life span: New findings based on measurement of total energy expenditure with doubly labeled water
Goran, M. I., Poehlman, É. T., & Johnson, R. K. (1995) · Nutrition Research · doi:10.1016/0271-5317(95)91657-x · Cited by 34 · see citing works
Gene expression profiling of human skeletal muscle in response to stabilized weight loss
Larrouy, D., Barbe, P., Valle, C., Dejean, S., Pelloux, V., Thalamas, C., Bastard, J., Bouil, A. L., Diquet, B., Clément, K., et al. (2008) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/88.1.125 · Cited by 32 · see citing works
Experimental demonstration of human weight homeostasis: implications for understanding obesity
Macías, A. E. (2004) · British Journal Of Nutrition · doi:10.1079/bjn20031051 · Cited by 32 · see citing works
How much may I eat? Calorie estimates based upon energy expenditure prediction equations
Heymsfield, S. B., Harp, J. B., Rowell, P. N., Nguyen, A. M., & Pietrobelli, A. (2006) · Obesity Reviews · doi:10.1111/j.1467-789x.2006.00249.x · Cited by 32 · see citing works
The role of altered sympathetic nervous system activity in the pathogenesis of obesity
Ravussin, É., & Tataranni, P. A. (1996) · Proceedings of The Nutrition Society · doi:10.1079/pns19960079 · Cited by 31 · see citing works
Moderate Walking Enhances the Effects of an Energy-Restricted Diet on Fat Mass Loss and Serum Insulin in Overweight and Obese Adults in a 12-Week Randomized Controlled Trial
Kleist, B., Wahrburg, U., Stehle, P., Schomaker, R., Greiwing, A., Stoffel‐Wagner, B., & Egert, S. (2017) · Journal of Nutrition · doi:10.3945/jn.117.251744 · Cited by 30 · see citing works
Long - Term Effects of Energy-Restricted Diets Differing in Glycemic Load on Metabolic Adaptation and Body Composition*
Das, S. K., Gilhooly, C. H., Golden, J. K., Pittas, A. G., Fuss, P., Dallal, G. E., McCrory, M. A., Saltzman, E. J., & Roberts, S. B. (2008) · The Open Nutrition Journal · doi:10.2174/1874288200802010076 · Cited by 26 · see citing works
Evaluation of older Adults with obesity for bariatric surgery: Geriatricians' perspective
Batsis, J. A., & Dolkart, K. M. (2015) · Journal of Clinical Gerontology and Geriatrics · doi:10.1016/j.jcgg.2015.01.001 · Cited by 25 · see citing works
No consistent evidence of a disproportionately low resting energy expenditure in long-term successful weight-loss maintainers
Ostendorf, D. M., Melanson, E. L., Caldwell, A. E., Creasy, S. A., Pan, Z., MacLean, P. S., Wyatt, H. R., Hill, J. O., & Catenacci, V. A. (2018) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqy179 · Cited by 26 · see citing works
Translational issues in targeting brown adipose tissue thermogenesis for human obesity management
Dulloo, A. G. (2013) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12304 · Cited by 25 · see citing works
Elevated adenosine deaminase activity in overweightand obese Indian subjects
Jadhav, A. A., & Jain, A. (2011) · Archives of Physiology and Biochemistry · doi:10.3109/13813455.2011.603341 · Cited by 25 · see citing works
Visceral adiposity is associated with increased lipid oxidation in obese, postmenopausal women
Nicklas, B., Goldberg, A., Bunyard, L., & Poehlman, É. T. (1995) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/62.5.918 · Cited by 25 · see citing works
The Influence of Energy Balance and Availability on Resting Metabolic Rate: Implications for Assessment and Future Research Directions
Siedler, M. R., Souza, M. J. D., Albracht‐Schulte, K., Sekiguchi, Y., & Tinsley, G. M. (2023) · Sports Medicine · doi:10.1007/s40279-023-01856-7 · Cited by 25 · see citing works
Effect of bariatric surgery on cardiometabolic risk in elderly patients: A population‐based study
Batsis, J. A., Miranda, W. R., Prasad, C., Collazo–Clavell, M. L., Sarr, M. G., Somers, V. K., & López-Jiménez, F. A. (2015) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1111/ggi.12527 · Cited by 23 · see citing works
ENERGY EXPENDITURE
DeLany, J. P., & Lovejoy, J. C. (1996) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(05)70357-1 · Cited by 22 · see citing works
Results of Bariatric Surgery
Hansen, E. N., Torquati, A., & Abumrad, N. N. (2006) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.26.061505.111242 · Cited by 22 · see citing works
Exercise and the Cisd2 Prolongevity Gene: Two Promising Strategies to Delay the Aging of Skeletal Muscle
Teng, Y., Wang, J.-Y., Chi, Y., & Tsai, T. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21239059 · Cited by 20 · see citing works
Metabolic Adaptations to Weight Loss
Hall, K. D. (2018) · Obesity · doi:10.1002/oby.22189 · Cited by 19 · see citing works
The Weight Loss Effects of Branched Chain Amino Acids and Vitamin B6: A Randomized Controlled Trial on Obese and Overweight Women
Novin, Z. S., Ghavamzadeh, S., & Mehdizadeh, A. (2018) · International Journal for Vitamin and Nutrition Research · doi:10.1024/0300-9831/a000511 · Cited by 18 · see citing works
The effects of weight reduction to ideal body weight on body fat distribution
Hendler, R., Welle, S. L., Statt, M., Barnard, R., & Amatruda, J. M. (1995) · Metabolism · doi:10.1016/0026-0495(95)90139-6 · Cited by 16 · see citing works
Self-citation
On adaptive thermogenesis: just another weight-loss tale?
Magkos, F. (2020) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqaa262 · Cited by 15 · see citing works
Obesity
Klein, S., & Romijn, J. A. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-29738-7.00036-8 · Cited by 14 · see citing works
Principles of Human Energy Metabolism
Galgani, J. E., & Ravussin, É. (2010) · Springer eBooks · doi:10.1007/978-1-4419-1607-5_1 · Cited by 12 · see citing works
Weight and body composition changes affect resting energy expenditure predictive equations during a 12‐month weight‐loss intervention
Dahle, J. H., Ostendorf, D. M., Pan, Z., MacLean, P. S., Bessesen, D. H., Heymsfield, S. B., Melanson, E. L., & Catenacci, V. A. (2021) · Obesity · doi:10.1002/oby.23234 · Cited by 10 · see citing works
1 Insulin action, thermogenesis and obesity
Cooney, G. J., & Storlien, L. H. (1994) · Baillière s Clinical Endocrinology and Metabolism · doi:10.1016/s0950-351x(05)80283-6 · Cited by 10 · see citing works
Etiology of Obesity: Methodological Examination of the Set‐Point Theory
Weinsier, R. L. (2001) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607101025003103 · Cited by 9 · see citing works
Use of [14C]-sodium bicarbonate/urea to measure total energy expenditure in overweight men and women before and after low calorie diet induced weight loss.
Luscombe‐Marsh, N. D., Tsopelas, C., Bellon, M., Clifton, P. M., Kirkwood, I. D., & Wittert, G. (2006) · PubMed · Cited by 9 · see citing works
Obesity and Metabolic Efficiency
Astrup, A. V. (2007) · Novartis Foundation symposium · doi:10.1002/9780470514962.ch10 · Cited by 9 · see citing works
Metabolic Consequences of Weight Reduction
ROSENBAUM, M. S. (2012) · Wiley eBooks · doi:10.1002/9781394323142.ch20 · Cited by 7 · see citing works
Principles of Energy Homeostasis
Ahima, R. S. (2015) · Springer eBooks · doi:10.1007/978-3-319-12125-3_48-1 · Cited by 5 · see citing works
Obesity
Klein, S., Fabbrini, E., & Romijn, J. A. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4377-0324-5.00036-5 · Cited by 4 · see citing works
Effects of total sleep deprivation on execution lapses during vigilance tasks
Li, J., Zhou, Y., Zhang, X., Wang, Q., & Zhang, L. (2022) · Chronobiology International · doi:10.1080/07420528.2022.2139185 · Cited by 4 · see citing works
Adaptive Responses to Weight Loss
ROSENBAUM, M. S., & Leibel, R. L. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1203-2_7 · Cited by 4 · see citing works
Is the Timing of Eating Relevant for Weight Loss?
Flanagan, A. (2025) · Proceedings of the Nutrition Society · doi:10.1017/s0029665124007547 · Cited by 2 · see citing works
Weight Loss Strategies
Roberts, S. B., Anton, S. D., & Dao, M. C. (2022) · Handbook of experimental pharmacology · doi:10.1007/164_2022_580 · Cited by 3 · see citing works
Effects of exercise training and a hypocaloric diet on female monozygotic twins in free-living conditions
Koenigstorfer, J., & Schmidt, W. (2011) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.07.033 · Cited by 3 · see citing works
Nutrition Discussion Forum
Westerterp, K. R. (2004) · British Journal Of Nutrition · doi:10.1079/bjn20041214 · Cited by 3 · see citing works
Principles of Energy Homeostasis
Ahima, R. S. (2023) · Springer eBooks · doi:10.1007/978-3-031-40116-9_48 · Cited by 2 · see citing works
Energy Expenditure in Obesity
Redman, L. M., & Ravussin, É. (2007) · Humana Press eBooks · doi:10.1007/978-1-59745-400-1_8 · Cited by 2 · see citing works
Energy Homeostasis
Kozak, L. P., & Ravussin, É. (2004) · CRC Press eBooks · doi:10.1201/9780203508756.pt1 · Cited by 2 · see citing works

Metabolic predictors of obesity. Contribution of resting energy expenditure, thermic effect of food, and fuel utilization to four-year weight gain of post-obese and never-obese women.
Weinsier, R. L., Nelson, K. M., Hensrud, D. D., Darnell, B. E., Hunter, G. R., & Schutz, Y. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117807 · Cited by 170 · see citing works
Changes in Energy Expenditure Resulting from Altered Body Weight
Leibel, R. L., Rosenbaum, M., & Hirsch, J. (1995) · New England Journal of Medicine · doi:10.1056/nejm199503093321001 · Cited by 2,012 · see citing works
Energy expenditure in lean and obese women: the role of posture allocation
Johannsen, D. L. (2006) · doi:10.31274/rtd-180813-220
Energy Expenditure Is Very High in Extremely Obese Women
Das, S. K., Saltzman, E. J., McCrory, M. A., Hsu, L. K. G., Shikora, S. A., Dolnikowski, G. G., Kehayias, J. J., & Roberts, S. B. (2004) · Journal of Nutrition · doi:10.1093/jn/134.6.1412 · Cited by 71 · see citing works
Effect of weight reduction on resting energy expenditure, substrate utilization, and the thermic effect of food in moderately obese women
Nelson, K., Weinsier, R., James, L., Darnell, B., Hunter, G., & Long, C. (1992) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/55.5.924 · Cited by 70 · see citing works

Authors: Amatruda, J. M., Statt, M. C., & Welle, S. L.
Affiliations: University of Rochester Medicine (US)
Venue: Journal of Clinical Investigation
Publisher: American Society for Clinical Investigation
Published: 1993-09-01
Volume: 92
Issue: 3
Pages: 1236-1242
ISSN: 0021-9738 (ISSN-L)
DOI: 10.1172/jci116695
PMC: PMC288263
OpenAlex: W2002036079
Cited by: 117
References: 38
Citations by year: 2025: 1 · 2023: 3 · 2022: 2 · 2021: 2 · 2020: 4 · 2019: 2 · 2018: 4 · 2017: 3 · 2016: 3 · 2015: 5 · 2014: 2 · 2013: 2 · 2012: 5
FWCI: 4.54
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Journal of Clinical Investigation (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5r01dk040816-07)
National Institute of Diabetes and Digestive and Kidney Diseases (DK40816)
National Center for Research Resources (RR-00044, M01RR000044)
Topics: Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
Keywords: obesity, total energy expenditure, resting metabolic rate, weight loss, ideal body weight, weight regain, body composition, body fat percentage, female obesity, energy balance, genetic predisposition to obesity
MeSH terms: Adult, Body Composition, Energy Metabolism, Female, Humans, Middle Aged, Obesity, Weight Loss

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Total and resting energy expenditure in obese women reduced to ideal body weight.

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks