The DOI matches its Crossref record; 201 of the 203 references it cites were found in a registry or an index.
Immune responses to stroke: mechanisms, modulation, and therapeutic potential.
Open accessAbstract
Stroke is the second leading cause of death worldwide and a leading cause of disability. Most strokes are caused by occlusion of a major cerebral artery, and substantial advances have been made in elucidating how ischemia damages the brain. In particular, increasing evidence points to a double-edged role of the immune system in stroke pathophysiology. In the acute phase, innate immune cells invade brain and meninges and contribute to ischemic damage, but may also be protective. At the same time, danger signals released into the circulation by damaged brain cells lead to activation of systemic immunity, followed by profound immunodepression that promotes life-threatening infections. In the chronic phase, antigen presentation initiates an adaptive immune response targeted to the brain, which may underlie neuropsychiatric sequelae, a considerable cause of poststroke morbidity. Here, we briefly review these pathogenic processes and assess the potential therapeutic value of targeting immunity in human stroke.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“numerous studies show that meningeal immune cells play an important role in the brain injury response”
From Living on the Edge of the CNS: Meninges Cell Diversity in Health and Disease (2021) · cites this paper as Iadecola et al., 2020
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Tissue Plasminogen Activator for Acute Ischemic Stroke
(1995) · New England Journal of Medicine · doi:10.1056/nejm199512143332401 · Cited by 11,654
Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct
Nogueira, R. G., Jadhav, A. P., Haussen, D. C., Bonafé, A., Budzik, R. F., Bhuva, P., Yavagal, D. R., Ribó, M., Cognard, C., Hanel, R. A., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1706442 · Cited by 5,667
Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging
Albers, G. W., Marks, M. P., Kemp, S. M., Christensen, S., Tsai, J. P.-C., Ortega‐Gutiérrez, S., McTaggart, R., Torbey, M., Kim‐Tenser, M. A., Leslie‐Mazwi, T. M., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1713973 · Cited by 4,966
Pathobiology of ischaemic stroke: an integrated view
Dirnagl, U., Iadecola, C., & Moskowitz, M. A. (1999) · Trends in Neurosciences · doi:10.1016/s0166-2236(99)01401-0 · Cited by 3,943
Self-citationJohnson, C. O., Nguyen, M., Roth, G. A., Nichols, E., Alam, S., Abate, D., Abd-Allah, F., Abdelalim, A., Abraha, H. N., Abu-Rmeileh, N. M., et al. (2019) · The Lancet Neurology · doi:10.1016/s1474-4422(19)30034-1 · Cited by 3,449
Thresholds in cerebral ischemia - the ischemic penumbra.
Astrup, J., Siesjö, B. K., & Symon, L. (1981) · Stroke · doi:10.1161/01.str.12.6.723 · Cited by 2,820
A Placebo-Controlled Trial of Oral Fingolimod in Relapsing Multiple Sclerosis
Kappos, L., Radue, E. W., O'Connor, P. W., Polman, C. H., Hohlfeld, R., Calabresi, P. A., Selmaj, K. W., Agoropoulou, C., Leyk, M., Zhang-Auberson, L., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa0909494 · Cited by 2,670
The immunology of stroke: from mechanisms to translation
Iadecola, C., & Anrather, J. (2011) · Nature Medicine · doi:10.1038/nm.2399 · Cited by 2,596
Self-citationBenardete, E. A., & Nair, A. K. (2015) · Cerebrovascular Diseases Extra · doi:10.1159/000370060 · Cited by 2,546
Genomic analysis of reactive astrogliosis
Zamanian, J. L., Xu, L., Foo, L. C., Nouri, N., Zhou, L., Giffard, R. G., & Barres, B. A. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.6221-11.2012 · Cited by 2,404
Flagged first, then by citations
2 of the 203 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Items 301–400 of 857
NLRX1 mediated impaired microglial phagocytosis of NETs in cerebral ischemia and reperfusion injury
Peng, J., Huang, Y., He, T., Zhan, Y., & Liu, J. (2025) · Cell Death and Differentiation · doi:10.1038/s41418-025-01526-3 · Cited by 12
Liu, H., Wang, P., Wu, L. H., Wu, F., Zhou, X., Li, Y., Su, H. F., Zang, J., Ji, X., Xiao, X., et al. (2025) · Diagnostics · doi:10.3390/diagnostics15222862 · Cited by 11
Jeon, J. H., Kaiser, E. E., Waters, E. S., Yang, X., Lourenco, J. M., Fagan, M. M., Scheulin, K. M., Sneed, S. E., Shin, S. K., Kinder, H. A., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-29282-9 · Cited by 11
Gelderblom, M., Koch, S., Strecker, J., Jørgensen, C., García‐Bonilla, L., Ludewig, P., Schädlich, I. S., Piepke, M., Degenhardt, K., Bernreuther, C., et al. (2023) · Brain Communications · doi:10.1093/braincomms/fcad090 · Cited by 11
Self-citationImportance of microRNAs by mRNA-microRNA integration analysis in acute ischemic stroke patients
Kanki, H., Matsumoto, H., Togami, Y., Okuzaki, D., Ogura, H., Sasaki, T., & Mochizuki, H. (2023) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2023.107277 · Cited by 11
Lin, F., Chen, X., Shi, Y., Yang, K., Hu, G., Zhuang, W., Lin, Y., Huang, T., Ye, Q., Cai, G., et al. (2024) · BMC Public Health · doi:10.1186/s12889-024-18588-6 · Cited by 11
Huang, Y., Wang, X., Li, Z., & Yin, X. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1408372 · Cited by 11
Wang, Q., Li, W.-N., Otkur, W., Cui, Y., & Chen, D. (2024) · Journal of Inflammation Research · doi:10.2147/jir.s460928 · Cited by 11
Research progress of small-molecule natural medicines for the treatment of ischemic stroke
Liu, K., Wang, L., & Pang, T. (2025) · Chinese Journal of Natural Medicines · doi:10.1016/s1875-5364(25)60801-6 · Cited by 11
Xu, M., Shan, Y., Luo, X., Xu, M., Hu, G., He, Z., Yang, X., & Gao, R. (2025) · PLoS ONE · doi:10.1371/journal.pone.0317710 · Cited by 11
Chen, S., Fu, P., Rastegar‐Kashkooli, Y., Zhu, L., Zong, Y., Huang, M., Gao, C., Wang, J., Zhang, J., Wang, J., et al. (2025) · Stroke · doi:10.1161/strokeaha.124.048507 · Cited by 11
Xie, Y., Liu, Z., Dan, B., Zou, L. P., Zhang, L., Zhang, R., Li, H., Cai, Q., Aiziretiaili, N., Ren, S., et al. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.966022 · Cited by 11
Mediation analysis of urinary metals and stroke risk by inflammatory markers
Zheng, L., Jing, X., Zhang, X., Zhong, C., Qiu, D., Yan, Q., & Gao, Z. (2023) · Chemosphere · doi:10.1016/j.chemosphere.2023.140084 · Cited by 11
Qin, R., Huang, L., Xu, W., Qin, Q., Liang, X., Lai, X., Huang, X., Xie, M., & Chen, L. (2023) · Mathematical Biosciences & Engineering · doi:10.3934/mbe.2023838 · Cited by 12
Li, Z., Gong, P., Zhang, M.-B., Li, C., Xiao, P.-L., Yu, M., Wang, X.-Z., An, L., Bi, F., Song, X., et al. (2023) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2023.110807 · Cited by 11
T cells direct microglial repair of white matter after stroke
Zera, K. A., & Buckwalter, M. S. (2021) · Trends in Neurosciences · doi:10.1016/j.tins.2021.07.005 · Cited by 11
Self-citationLiu, Q., Ma, H., Liao, J., Zhu, Z., Chen, H., Sun, D. I., Wang, L., Lu, L., Chen, X., Zhang, X., et al. (2025) · Theranostics · doi:10.7150/thno.115993 · Cited by 10
Rab7a is required to degrade select blood-brain barrier junctional proteins after ischemic stroke
Cottarelli, A., Jamoul, D., Tuohy, M. C., Shahriar, S., Glendinning, M. D., Prochilo, G., Edinger, A. L., Arac, A., & Agalliu, D. (2025) · Acta Neuropathologica Communications · doi:10.1186/s40478-025-02125-6 · Cited by 10
Nanoparticle-Mediated Nose-to-Brain Delivery for Ischemic Stroke Therapy: Preclinical Insights
Park, J., & Riew, T. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17111447 · Cited by 10
Zhang, C., Wang, L., Guo, Y., & Feng, W. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1082546 · Cited by 11
Che, F., Zhao, X., Ding, Y., Wang, A., Cheng, Z., Tong, Y., Duan, H., Han, Z., & Geng, X. (2023) · World Neurosurgery · doi:10.1016/j.wneu.2023.11.151 · Cited by 10
Incidence and influencing factors of urinary incontinence in stroke patients: A meta‐analysis
Wang, S., Kang, H., Wang, Q., Wang, D., Hu, L., Kou, J., & Yang, Z. (2024) · Neurourology and Urodynamics · doi:10.1002/nau.25398 · Cited by 10
Ding, L., Wang, J., Qiu, S., Ren, Z., Li, Y., & An, P. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04176-7 · Cited by 11
Jiang, N., Wang, C., Xie, B., Xie, H., Wu, A., Kong, X., Gu, L., Jiang, Y. Q., & Peng, J. (2024) · Neurobiology of Disease · doi:10.1016/j.nbd.2024.106583 · Cited by 10
Lian, J., Yang, L., Tan, H., Su, S., Lopes, L. S., Cheng, F., Yan, J., Fu, Y., Fu, W., Xie, Z., et al. (2024) · Science China Life Sciences · doi:10.1007/s11427-024-2592-4 · Cited by 10
Cipriani, R., Domerq, M., Martín, A., & Matute, C. (2024) · Advances in neurobiology · doi:10.1007/978-3-031-55529-9_23 · Cited by 10
Liang, J., Zhu, Y., Liu, S., Kuang, B., Tian, Z., Zhang, L., Yang, S., Lin, M., Chen, N., Liu, X., et al. (2024) · Phytotherapy Research · doi:10.1002/ptr.8322 · Cited by 13
Xue, H., Zeng, Y., Zou, X., & Li, Y. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2024.1431727 · Cited by 11
Time of day dependent reduction in stroke infarct volume by the Reverb agonist SR9009 in mice
Kamat, P. K., Khan, M. B., Siddiqui, S., Hattaway, T. G., Anas, A., Rudic, R. D., Baban, B., Dhandapani, K. M., & Hess, D. C. (2024) · Experimental Neurology · doi:10.1016/j.expneurol.2024.115067 · Cited by 10
Zhang, Z., Zhang, M., Li, D., Shu, R., Pan, Q., Zou, W., Wang, K., & Yin, Y. (2025) · Inflammation · doi:10.1007/s10753-025-02287-4 · Cited by 10
Delayed Transplantation of Neural Stem Cells Improves Initial Graft Survival after Stroke
Weber, R., Rentsch, N. H., Buil, B. A., Generali, M., Nih, L. R., Tackenberg, C., & Rust, R. (2025) · Advanced Science · doi:10.1002/advs.202504154 · Cited by 10
Bao, H., Li, J., Zhang, B., Huang, J., Su, D., & Liu, L. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1113634 · Cited by 9
Guido, G., Crivellaro, E., Fortunato, G. D., & Melloni, L. (2022) · Brain Research · doi:10.1016/j.brainres.2022.147888 · Cited by 11
Shao, J., Yin, X. L., Lang, Y., Ding, M., Zhang, B., Sun, Q., Jiang, X., Song, J., & Cui, L. (2022) · Molecular Neurobiology · doi:10.1007/s12035-022-03099-5 · Cited by 12
Mapping brain–immune interactions in ischemic stroke
Jiang, D., & McCullough, L. D. (2024) · Nature Immunology · doi:10.1038/s41590-024-01747-7 · Cited by 10
Sun, W., Yang, Z., Wang, Y., Miao, J., Pan, C., Li, G., Liang, W., Zhao, X., Lan, Y., Qiu, X., et al. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.05.045 · Cited by 10
Li, X., Pan, M., Tian, X., Yang, L., Zhang, J., Yan, D., Xu, B., Zhao, L., & Fang, W. (2024) · Journal of Inflammation Research · doi:10.2147/jir.s469651 · Cited by 9
Frydrychowicz, M., Telec, M., Anioła, J., Kaźmierski, R., Chowaniec, H., Dworacki, G., Wojtasz, I., Kozubski, W. P., & Łukasik, M. (2024) · Cells · doi:10.3390/cells13161401 · Cited by 9
Sajanti, A., Hellström, S., Bennett, C., Srinath, A., Jhaveri, A., Cao, Y. J., Takala, R. S. K., Frantzén, J., Koskimäki, F., Falter, J., et al. (2024) · Inflammation · doi:10.1007/s10753-024-02185-1 · Cited by 9
Association of physical activity, sedentary behavior and stroke in older adults
Bai, L., Wen, Z., Yan, X., Wu, S., & Chen, J. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1484765 · Cited by 9
Molecular heterogeneity in human stroke – What can we learn from the peripheral blood transcriptome?
Stamova, B. S., Knepp, B., & Rodríguez, F. (2025) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x251322598 · Cited by 11
A minimally invasive thrombotic model to study stroke in awake mice
Marks, K., Ahn, S. J., Rai, N., Anfray, A., Iadecola, C., & Anrather, J. (2025) · Nature Communications · doi:10.1038/s41467-025-59617-1 · Cited by 11
Self-citationLiu, T., Huang, G., Guo, X., Ji, Q., Yu, L., Zong, R., Li, Y., Song, X., Fu, Q., Xue, Q., et al. (2025) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2025.06.005 · Cited by 9
Transcriptional and neuroprotective effects of hexokinase-2 inhibitors administered after stroke
Won, S. J., Uruk, G., Mai, N., Tu, C., Ogut, D., Asatryan, S., Mocanu, E., Shon, R., Kim, K. S., Awakoaiye, K., et al. (2025) · Journal of Neuroinflammation · doi:10.1186/s12974-025-03594-1 · Cited by 9
Wu, Y., Lv, W., Xiong, S., Cao, G., Fu, L., Liu, W., Shao, F., Mei, Y., & Lv, Y. (2025) · Phytomedicine · doi:10.1016/j.phymed.2025.157508 · Cited by 9
Stem cell-mediated recovery in stroke: partnering with the immune system
McMillan, N., McMillan, A., Kiliaan, P. C. J., Yahya, T., Thakkar, R., Weiner, H. L., Smirnakis, S. M., Yavagal, D. R., & Izzy, S. (2025) · Nature reviews. Neuroscience · doi:10.1038/s41583-025-00985-4 · Cited by 9
Chen, X., Zhao, X., Fei, H., Zhang, Y., Pang, J., Liu, Z., Wang, W., Qiao, J., & Cuiping, X. (2025) · Cardiovascular Diabetology · doi:10.1186/s12933-025-03038-3 · Cited by 9
The complement cascade in Alzheimer’s disease: modern implications of an ancient immune protagonist
Papavergi, M.-T., Bathini, P., Singh, B. B., & Lemere, C. A. (2025) · Molecular Neurodegeneration · doi:10.1186/s13024-025-00916-y · Cited by 12
Unveiling Leukocyte Extracellular Traps in Inflammatory Responses of the Central Nervous System
Colciaghi, F., & Costanza, M. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.915392 · Cited by 9
Multiscale imaging informs translational mouse modeling of neurological disease
Wang, Y., LeDue, J. M., & Murphy, T. H. (2022) · Neuron · doi:10.1016/j.neuron.2022.09.006 · Cited by 13
Cai, J., Ye, Z., Hu, Y., Yang, J., Wu, L., Yuan, F., Zhang, L., Chen, Q., & Zhang, S. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.1094500 · Cited by 9
Fu, L., Yu, B., Zhang, Y., Cao, S., lv, B., Tian, Y., Chen, H., Yang, S., Hu, Y., Hua, J., et al. (2023) · Aging · doi:10.18632/aging.204804 · Cited by 11
Saleh, R. O., Majeed, A. A., Margiana, R., Alkadir, O. K. A., Almalki, S. G., Ghildiyal, P., Samusenkov, V. O., Jabber, N. K., Mustafa, Y. F., & Elawady, A. (2024) · Cell Biochemistry and Function · doi:10.1002/cbf.3957 · Cited by 9
Yao, Y., Ni, W., Feng, L., Meng, J., Tan, X., Chen, H., Shen, J., & Zhao, H. (2024) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.14849 · Cited by 9
Drag, L. L., Mlynash, M., Nassar, H., Osborn, E., Kim, D. E., Angst, M. S., Aghaeepour, N., Buckwalter, M. S., & Lansberg, M. G. (2020) · BMC Neurology · doi:10.1186/s12883-020-01897-9 · Cited by 9
Self-citationCOVID-19 Pathology on Various Organs and Regenerative Medicine and Stem Cell-Based Interventions
Arjmand, B., Alavi-Moghadam, S., Roudsari, P. P., Rezaei–Tavirani, M., Rahim, F., Gilany, K., Mohamadi-Jahani, F., Adibi, H., & Larijani, B. A. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.675310 · Cited by 9
Yang, C., Yuan, F., Shao, W., Yao, L., Jin, S., & Han, F. (2022) · Genetics and Molecular Biology · doi:10.1590/1678-4685-gmb-2022-0119 · Cited by 9
Shang, Y., Liu, S., Liang, C., Du, K., Chen, S., Li, J., Jin, H., & Chang, Y. (2022) · International Journal of Analytical Chemistry · doi:10.1155/2022/8774913 · Cited by 8
Zhao, N., Li, J., Zhang, Q., Yang, L., & Zhang, L. (2023) · Clinical Neurology and Neurosurgery · doi:10.1016/j.clineuro.2023.107720 · Cited by 8
Yan, X., Wang, B., Xia, P., Chen, L., Wang, Q., Ge, W., Zhou, Y., & Jiang, C. (2023) · Clinical and Applied Thrombosis/Hemostasis · doi:10.1177/10760296231213070 · Cited by 8
Microglial Inflammatory Mechanisms in Stroke: The Jury Is Still Out
Benkő, S., & Dénes, Á. (2024) · Neuroscience · doi:10.1016/j.neuroscience.2024.02.007 · Cited by 9
Lin, L., Yang, J., Fu, W., Liu, X., Liu, Y., & Zou, L. P. (2024) · Frontiers in Medicine · doi:10.3389/fmed.2024.1457364 · Cited by 8
Castillo-González, J., Buscemi, L., Vargas-Rodríguez, P., Serrano-Martínez, I., Forte‐Lago, I., Caro, M., Price, M., Hernández‐Cortés, P., Hirt, L., & González‐Rey, E. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107501 · Cited by 8
Tian, A., Zheng, Y., Jin, J., & Huang, C.-Y. (2025) · Frontiers in Neurology · doi:10.3389/fneur.2025.1538352 · Cited by 8
Advanced Biosensing Technologies: Leading Innovations in Alzheimer’s Disease Diagnosis
Benjamin, S. R., de Lima, F., Nunes, P. I. G., Dutra, R. F., de Andrade, G. M., & Oriá, R. B. (2025) · Chemosensors · doi:10.3390/chemosensors13060220 · Cited by 10
Hao, Y.-X., Li, C., Lu, Z., Kong, N., Huang, R.-H., Ma, S., Zhou, W.-F., Jiao, H., Qiu, Y., Yu, Y.-F., et al. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-06736-4 · Cited by 11
Thougaard, E., Nielsen, P. V., Raffaele, S., Nielsen, A.-S. N., Larsen, L. L., Corradini, S., Havelund, J. F., Becirovic, L. V., Bouwman, E. M., Fumagalli, M., et al. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118334 · Cited by 8
Zhou, X., Gu, Y., & Li, L. (2025) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2025.123620 · Cited by 8
Multi-omics integrative analysis reveals novel genetic loci and candidate genes for ischemic stroke
Wang, M., Xu, C. B., Du, X., Zhu, T., Yang, X., Duan, F., Wang, G., Zuo, Y., Chen, H., & Wang, G. (2025) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2025.102633 · Cited by 8
Zhai, Z., & Gao, Y. (2025) · Journal of Ginseng Research · doi:10.1016/j.jgr.2025.08.007 · Cited by 8
Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort
Chen, S., Huang, W., Liu, Y., Chen, X., Ke, B., Shen, Q., Cai, H., Sun, J., Li, Y., Cao, Y., et al. (2025) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.70252 · Cited by 8
Review: Systemic inflammation after stroke. Therapy and perspective
Abuzan, M., Cercel, A., Doeppner, T. R., Hermann, D. M., Surugiu, R., Pîrșcoveanu, D. F. V., & Popa‐Wagner, A. (2026) · GeroScience · doi:10.1007/s11357-025-02070-1 · Cited by 8
Farooqui, M., Ortega‐Gutiérrez, S., Hernandez, K., Torres, V. O., Dajles, A., Zevallos, C. B., Quispe‐Orozco, D., Mendez‐Ruiz, A., Manzel, K. W., Eyck, P. T., et al. (2022) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.51719 · Cited by 8
Structure, function and mechanism of edible fungus polysaccharides in human beings chronic diseases
Liu, H., Xiaoyi, L. I. U., Xie, J., & Shuai, C. H. E. N. (2023) · Food Science and Technology · doi:10.1590/fst.111022 · Cited by 8
Yang, Z., He, M., Zhang, Q., Li, S., Chen, H., & Liao, D. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2023.1004457 · Cited by 8
Thougaard, E., Nielsen, P. V., Forsberg, A., Phuong, V., Velasco, A. M., Włodarczyk, A., Wajant, H., Lang, I., Mikkelsen, J. D., Clausen, B. H., et al. (2023) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2023.578246 · Cited by 8
Chen, X., Xu, X., Li, Y., Liu, F., Zhang, B., & Zuo, L. (2023) · Brain and Behavior · doi:10.1002/brb3.3364 · Cited by 8
Pu, Y., Cheng, J., Wang, Z., Zhang, J., Fajun, L., Zhang, X., Zheng, Z., Yin, M., & Wang, Z. (2025) · PubMed · doi:10.14670/hh-18-780 · Cited by 8
Mechanistic exploration of ubiquitination-mediated pathways in cerebral ischemic injury
Khanra, S., Singh, S., & Singh, T. G. (2024) · Molecular Biology Reports · doi:10.1007/s11033-024-10123-5 · Cited by 9
Kim, D., Morikawa, S., Nakagawa, T., Okano, H., & Kase, Y. (2025) · Experimental Neurology · doi:10.1016/j.expneurol.2025.115177 · Cited by 8
Shen, Y., Yang, R., Zhou, R., Lu, W., Li, L., Niu, Z., Chen, M., Wang, J., Wang, Y., Fang, L., et al. (2021) · BioMed Research International · doi:10.1155/2021/5575443 · Cited by 8
Identification of immune characteristic landscapes related to autophagy in ischemic stroke
Li, S., Zhang, Y., Shi, S., Guo, D., & Chang, T. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.1026578 · Cited by 8
Shen, X.-Y., Han, Y., Gao, Z.-K., Han, P.-P., & Bi, X. (2022) · Molecular Biology Reports · doi:10.1007/s11033-022-08184-5 · Cited by 7
Santo, C. D., Russa, D. L., Greco, R., Persico, A., Zanaboni, A. M., Bagetta, G., & Amantea, D. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065800 · Cited by 8
Laichinger, K., Bombach, P., Dünschede, J., Ruschil, C., Stefanou, M., Dubois, E., Poli, S., Feil, K., Ziemann, U., Kowarik, M. C., et al. (2023) · PLoS ONE · doi:10.1371/journal.pone.0283476 · Cited by 8
Development and Validation of Ischemic Events Related Signature After Carotid Endarterectomy
Guo, C., Liu, Z., Cao, C., Zheng, Y., Lu, T., Yin, Y., Wang, L., Liu, L., Liu, S., Hua, Z., et al. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.794608 · Cited by 8
Shim, B., Ciryam, P., Tosun, Ç., Serra, R., Tsymbalyuk, N., Keledjian, K., Gerzanich, V., & Simard, J. M. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26010309 · Cited by 5
Wang, G., Hu, H., Liu, J., Fei, X., Dou, Y., Wang, L. P., Lin, Y., Hu, G., Zhang, D., Jiang, L., et al. (2025) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-025-01566-w · Cited by 7
Dong, M.-Q., Chen, Y., Wang, Q., Li, H., Bai, L.-Y., Cao, X., & Xu, Y. (2025) · Neuropharmacology · doi:10.1016/j.neuropharm.2025.110528 · Cited by 7
Guo, S., Wang, Z., Shi, R., Huang, P., Fang, Y., Chen, S., Huang, M. J., Hu, J. P., Lu, Y., Xu, X., et al. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.114080 · Cited by 9
Neuroprotective mechanisms of Buyang Huanwu decoction in ischemic stroke
Qin, Y., Hu, S., Mawen, S., Pan, S.-Y., Huai, Y., Liang, G., Chen, T., Zhao, F., Dong, H., Yao, X., et al. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1620533 · Cited by 7
New mechanisms of aging: From vascular to neurological system
Hu, Q., Zhang, F., Wang, H., Wang, R., Zhang, D., Fu, R., Zhu, M., Zhang, H., Gu, M., Shao, C., et al. (2025) · Brain Behavior and Immunity Integrative · doi:10.1016/j.bbii.2025.100143 · Cited by 8
Fakharaldeen, Z. A., Al-Mudhafar, A. M., Gany, S. N., Radhi, A. N., & Hadi, N. R. (2023) · Journal of Medicine and Life · doi:10.25122/jml-2023-0099 · Cited by 7
Gong, H., Li, Z., Huang, G., & Mo, X. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e32171 · Cited by 7
Choline consumption reduces CVD risk via body composition modification
Wang, H., Lin, J., Fan, S., Zhang, X., Zhou, T., Luo, R., Zhang, C., Zhang, S., Yang, Q., & Hu, R. (2024) · Scientific Reports · doi:10.1038/s41598-024-66039-4 · Cited by 7
Xin Min, Z. H. O. U., Xue, S., Si, X., Du, W., Guo, Y., Qu, Y., Guo, Z., & Sun, X. (2024) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.70023 · Cited by 7
Du, Y., Li, Y., Ye, F., Cai, H., Huang, W., Liu, T., Xue, X., & Feng, G. (2025) · Experimental Neurology · doi:10.1016/j.expneurol.2025.115318 · Cited by 9
Lu, L., Zhu, J., Zhang, H., Li, X., & Chen, K. (2022) · Cerebrovascular Diseases · doi:10.1159/000524414 · Cited by 7
Mathematical modelling of haemorrhagic transformation within a multiscale microvasculature network
Wang, J., van Kranendonk, K. R., El‐Bouri, W. K., Majoie, C. B. L. M., & Payne, S. J. (2022) · Physiological Measurement · doi:10.1088/1361-6579/ac6cc5 · Cited by 7
Schädlich, I. S., Schnapauff, O., Kuchenbecker-Pöls, L., Schrader, J., Tolosa, E., Rissiek, B., & Magnus, T. U. (2022) · iScience · doi:10.1016/j.isci.2022.104470 · Cited by 7
Metadata
- Authors
- Iadecola, C., Buckwalter, M. S., & Anrather, J.
- Affiliations
- Weill Cornell Medicine (US)
- Stanford Medicine (US)
- Corresponding author
- Iadecola, Costantino
- Venue
- Journal of Clinical Investigation
- Published
- 2020-05-11
- Volume
- 130
- Issue
- 6
- Pages
- 2777-2788
- ISSN
- 0021-9738 (ISSN-L)
- 1558-8238
- PMC
- PMC7260029
- OpenAlex
- W3022448963
- Cited by
- 853
- References
- 203
- Citations by year
- 2026: 151 · 2025: 171 · 2024: 175 · 2023: 167 · 2022: 128 · 2021: 49 · 2020: 10
- FWCI
- 8.84
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Investigation (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- American Heart Association (19PABHI34580007)
- National Institutes of Health (NS34179, R01-NS34179)
- College of Veterinary Medicine, Cornell University
- National Institute of Neurological Disorders and Stroke (R01NS034179, R01NS081179, R01NS094507)
- Topics
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Health Sciences › Medicine › Clinical Neurology › Acute Ischemic Stroke Management
- Health Sciences › Medicine › Clinical Neurology › Intracerebral and Subarachnoid Hemorrhage Research
- Keywords
- stroke, immune response, ischemic stroke, innate immunity, adaptive immunity, neuroinflammation, secondary infection, antigen presentation, neuropsychiatric sequelae, immunomodulatory therapy, cerebral ischemia
- MeSH terms
- Animals, Brain Ischemia, Humans, Inflammation, Stroke, Adaptive Immunity
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
