The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Islet β cell expression of constitutively active Akt1/PKBα induces striking hypertrophy, hyperplasia, and hyperinsulinemia
Open accessAbstract
Generation of transgenic mice.The constitutively active Akt1 used for these experiments lacks the PH domain (Akt∆4-129) and contains an N-terminal Src myristolation signal (myrAkt∆4-129) along with an hemag-
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Citations
Cites
Cellular survival: a play in three Akts
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“Interestingly, loss of Cdk-4 in mice resulted in insulin-dependent diabetes, while activation of Cdk-4 produced β-cell hyperplasia (31).”
Background
Research works printed but not linked: 31
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Cited by
Mechanisms linking obesity to insulin resistance and type 2 diabetes
Kahn, S. E., Hull, R. L., & Utzschneider, K. M. (2006) · Nature · doi:10.1038/nature05482 · Cited by 5,448
Garofalo, R. S., Orena, S. J., Rafidi, K., Torchia, A. J., Stock, J. L., Hildebrandt, A. L., Coskran, T., Black, S. C., Brees, D. J., Wicks, J. R., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci16885 · Cited by 726
Regulation of pancreatic beta-cell mass
Bouwens, L., & Rooman, I. (2005) · Physiological Reviews · doi:10.1152/physrev.00025.2004 · Cited by 411
Protein Kinase Bα/Akt1 Regulates Placental Development and Fetal Growth
Yang, Z.-Z., Tschopp, O., Hemmings-Mieszczak, M., Feng, J., Brodbeck, D., Perentes, E., & Hemmings, B. A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m302847200 · Cited by 384
Constitutively active Akt induces enhanced myelination in the CNS
Flores, A. I., Narayanan, S. P., Morse, E. N., Shick, H. E., Yin, X., Kidd, G., Avila, R. L., Kirschner, D. A., & Macklin, W. B. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.0150-08.2008 · Cited by 361
Metadata
- Authors
- Bernal-Mizrachi, E., Wen, W., Stahlhut, S., Welling, C. M., & Permutt, M. A.
- Venue
- Journal of Clinical Investigation
- Published
- 2001-12-01
- Volume
- 108
- Issue
- 11
- Pages
- 1631-1638
- ISSN
- 0021-9738 (ISSN-L)
- OpenAlex
- W4255925138
- Cited by
- 332
- References
- 2
- FWCI
- 12.11
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Bernal-Mizrachi, E., Wen, W., Stahlhut, S., Welling, C. M., & Permutt, M. A. (2001). Islet β cell expression of constitutively active Akt1/PKBα induces striking hypertrophy, hyperplasia, and hyperinsulinemia. Journal of Clinical Investigation. https://doi.org/10.1172/jci200113785
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
