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Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation
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“Additionally, JNK activation and its downstream target c-Jun have been implicated in RANKL-induced c-Fos and NFATc1 expression in osteoclast precursors [30,31].”
From Anti-Osteoporotic Potential of Water Extract of Anethum graveolens L. Seeds (2023) · cites this paper as [30]
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Cites
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph node organogenesis.
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Self-citationSP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
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Transcriptional regulation by calcium, calcineurin, and NFAT
Hogan, P. G., Chen, L., Nardone, J., & Rao, A. (2003) · Genes & Development · doi:10.1101/gad.1102703 · Cited by 1,991
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Cited by
Autoamplification of NFATc1 expression determines its essential role in bone homeostasis
Asagiri, M., Sato, K., Usami, T., Ochi, S., Nishina, H., Yoshida, H., Morita, I., Wagner, E. F., Mak, T. W., Serfling, E., et al. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20051150 · Cited by 849
Osteoclasts: What Do They Do and How Do They Do It?
Teitelbaum, S. L. (2007) · The American Journal of Pathology · doi:10.2353/ajpath.2007.060834 · Cited by 730
The cell biology of bone metabolism
Datta, H. K., Ng, W. F., Walker, J. A., Tuck, S. P., & Varanasi, S. S. (2008) · Journal of Clinical Pathology · doi:10.1136/jcp.2007.048868 · Cited by 614
The role of NFAT in osteoclast formation
TAKAYANAGI, H. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1402.071 · Cited by 442
Mechanistic insight into osteoclast differentiation in osteoimmunology
Takayanagi, H. (2005) · Journal of Molecular Medicine · doi:10.1007/s00109-004-0612-6 · Cited by 413
Metadata
- Authors
- Ikeda, F., Nishimura, R., Matsubara, T., Tanaka, S., Inoue, J.-I., Reddy, S. V., Hata, K., Yamashita, K., Hiraga, T., Watanabe, T., Kukita, T., Yoshioka, K., Rao, A., & Yoneda, T.
- Venue
- Journal of Clinical Investigation
- Published
- 2004-08-16
- Volume
- 114
- Issue
- 4
- Pages
- 475-484
- ISSN
- 0021-9738
- Cited by
- 417
- References
- 7
- Language
- en
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- CoChat. (2026). Citation check: Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation. https://app.cochat.ai/papers/10.1172/jci200419657
- The paper
- Ikeda, F., Nishimura, R., Matsubara, T., Tanaka, S., Inoue, J.-I., Reddy, S. V., Hata, K., Yamashita, K., Hiraga, T., Watanabe, T., Kukita, T., Yoshioka, K., Rao, A., & Yoneda, T. (2004). Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation. Journal of Clinical Investigation. https://doi.org/10.1172/jci200419657
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.