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Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemia
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Serum cholesterol is much higher in LDLR-null than in arh-deleted mice.
“serum cholesterol is much higher in LDLR-null than in arh-deleted mice”
From Endocytic adaptors Arh and Dab2 control homeostasis of circulatory cholesterol (2016) · cites this paper as [20]
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“Mice lacking ARH were crossed with mice containing loxP sites at the LRP locus (26, 27) to generate Arh–/–Lrplox/lox animals.”
MethodSelf-citationARH Is a Modular Adaptor Protein That Interacts with the LDL Receptor, Clathrin, and AP-2
He, G., Gupta, S., Yi, M., Michaely, P., Hobbs, H. H., & Cohen, J. C. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m208539200 · Cited by 232
Self-citationExperiences with the Homozygous Cases of Familial Hypercholesterolemia
Khachadurian, A. K., & Uthman, S. M. (1973) · Annals of Nutrition and Metabolism · doi:10.1159/000175431 · Cited by 185
Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptors
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Self-citationMichaely, P., Li, W.-P., Anderson, R. G. W., Cohen, J. C., & Hobbs, H. H. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m405242200 · Cited by 66
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Cited by
Sorted by citations
Smagris, E., Gilyard, S., BasuRay, S., Cohen, J. C., & Hobbs, H. H. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.719955 · Cited by 226
Self-citationCCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL
Bartuzi, P., Billadeau, D. D., Favier, R., Rong, S., Dekker, D., Fedoseienko, A., Fieten, H., Wijers, M., Levels, J. H., Huijkman, N., et al. (2016) · Nature Communications · doi:10.1038/ncomms10961 · Cited by 205
Mahley, R. W., & Huang, Y. (2007) · Journal of Clinical Investigation · doi:10.1172/jci30889 · Cited by 159
Endocytosis and Physiology: Insights from Disabled-2 Deficient Mice
Tao, W., Moore, R., Smith, E. R., & Xu, X.-X. (2016) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2016.00129 · Cited by 43
Endocytic adaptors Arh and Dab2 control homeostasis of circulatory cholesterol
Tao, W., Moore, R., Meng, Y., Smith, E. R., & Xu, X.-X. (2016) · Journal of Lipid Research · doi:10.1194/jlr.m063065 · Cited by 32
Metadata
- Authors
- Jones, C., Garuti, R., Michaely, P., Li, W.-P., Maeda, N., Cohen, J. C., Herz, J., & Hobbs, H. H.
- Venue
- Journal of Clinical Investigation
- Published
- 2007-01-02
- Volume
- 117
- Issue
- 1
- Pages
- 165-174
- ISSN
- 0021-9738
- Cited by
- 52
- References
- 6
- Language
- en
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