Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ

Molecular Mechanisms of Stress-Responsive Changes in Collagen and Elastin Networks in Skin

Aziz, J., Shezali, H., Radzi, Z., Yahya, N. A., Abu Kassim, N. H., Czernuszka, J., & Rahman, M. T. (2016) · Skin Pharmacology and Physiology · doi:10.1159/000447017 · Cited by 7,323

Liver fibrosis

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The Versatile Role of microRNA-30a in Human Cancer

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Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.

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Epithelial-mesenchymal transition and its implications for fibrosis

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Molecular Regulation of Hepatic Fibrosis, an Integrated Cellular Response to Tissue Injury

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Liver fibrosis – from bench to bedside

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Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair

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Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes

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Decreased collagen types I and IV, laminin, CK-19 and α-SMA expression after bone marrow cell transplantation in rats with liver fibrosis

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Identifying Molecular Factors That Contribute to Resolution of Liver Fibrosis

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Role of regulatory T cells in inflammatory liver diseases

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Extracellular histones stimulate collagen expression in vitro and promote liver fibrogenesis in a mouse model via the TLR4-MyD88 signaling pathway

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New Biomarkers in Liver Fibrosis: A Pass through the Quicksand?

Tagliaferro, M., Marino, M., Basile, V., Pocino, K., Rapaccini, G. L., Ciasca, G., Basile, U., & Carnazzo, V. (2024) · Journal of Personalized Medicine · doi:10.3390/jpm14080798 · Cited by 21

Myeloid-specific SIRT1 Deletion Aggravates Hepatic Inflammation and Steatosis in High-fat Diet-fed Mice

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Optical diagnosis of the progression and reversal of CCl 4 -induced liver injury in rodent model using minimally invasive autofluorescence spectroscopy

Nazeer, S. S., Sandhyamani, S., & Jayasree, R. S. (2015) · The Analyst · doi:10.1039/c4an01507j · Cited by 18

Histopathologic Evaluation of Liver Biopsy for Cirrhosis

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Fuzheng Huayu Capsule Attenuates Hepatic Fibrosis by Inhibiting Activation of Hepatic Stellate Cells

Wu, M., Zhou, Y., Qin, S.-L., Lin, L., Jian, P., Zhang, T., Zhang, J., Xu, L., & Wu, J. H. (2020) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2020/3468791 · Cited by 20

The role of Mesothelin signaling in Portal Fibroblasts in the pathogenesis of cholestatic liver fibrosis

Fuji, H., Miller, G., Nishio, T., Koyama, Y., Lam, K., Zhang, V., Loomba, R. S., Brenner, D. A., & Kisseleva, T. (2021) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2021.790032 · Cited by 18

The mouse Anxa6/miR-9-5p/Anxa2 axis modulates TGF-β1-induced mouse hepatic stellate cell (mHSC) activation and CCl4-caused liver fibrosis

Liao, J., Zhang, Z., Yuan, Q., Luo, L., & Hu, X. (2022) · Toxicology Letters · doi:10.1016/j.toxlet.2022.04.004 · Cited by 18

15-Deoxy-Δ12,14-prostaglandin J2 inhibits fibrogenic response in human hepatoma cells

Suk, F., Chen, C.-H., Lin, S.-Y., Cheng, C.-J., Yen, S.-J., Hung, L.-F., Liu, D.-Z., & Liang, Y. (2009) · Toxicology Letters · doi:10.1016/j.toxlet.2009.01.019 · Cited by 18

Wound healing and local neuroendocrine regulation in the injured liver

Ebrahimkhani, M. R., Elsharkawy, A. M., & Mann, D. A. (2008) · Expert Reviews in Molecular Medicine · doi:10.1017/s146239940800063x · Cited by 18

Biomechanics and functionality of hepatocytes in liver cirrhosis

Sun, S., Song, Z., Cotler, S. J., & Cho, M. (2013) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2013.10.050 · Cited by 18

TREM2 protects against inflammation by regulating the release of mito-DAMPs from hepatocytes during liver fibrosis

Shan, S., Chao, S., Liu, Z., Wang, S., Liu, Z., Zhang, C., Cheng, D., Su, Z., & Song, F. (2024) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2024.05.004 · Cited by 17

Mineralocorticoid receptors in non‐alcoholic fatty liver disease

Schreier, B., Zipprich, A., Uhlenhaut, N. H., & Gekle, M. (2021) · British Journal of Pharmacology · doi:10.1111/bph.15784 · Cited by 16

Treatment of Liver Fibrosis: A 20-Year Bibliometric and Knowledge-Map Analysis

Dai, Y., Zhao, Z., & Liu, C. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.942841 · Cited by 16

Inflammation activity affects liver stiffness measurement by magnetic resonance elastography in MASLD

Wei, X., Shi, Q. W., Wei, X., Qiu, L., Du, X., Liu, Y., Xu, H., Zhao, J., Chen, S., & Zhang, J. (2024) · Digestive and Liver Disease · doi:10.1016/j.dld.2024.04.031 · Cited by 17

Stellate Cells and Hepatic Fibrosis

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Pathophysiology of Portal Hypertension

Morales‐Ruiz, M., Rodríguez‐Vita, J., Ribera, J., & Jiménez, W. (2015) · Springer eBooks · doi:10.1007/978-3-642-37078-6_144 · Cited by 17

Detection of Steatohepatitis in a Rat Model by Using Spectroscopic Shear-Wave US Elastography

Kazemirad, S., Zhang, E. W., Nguyen, B., Bodson‐Clermont, P., Destrempes, F., Trudel, D., Cloutier, G., & Tang, A. (2016) · Radiology · doi:10.1148/radiol.2016160308 · Cited by 17

Dysregulation of fibrosis related genes in HCV induced liver disease

Dawood, R. M., El-Meguid, M. A., Ibrahim, M. K., Din, N. G. B. E., Barakat, A., El-Wakeel, K. H., Alla, M. D. A. A., Wu, G. Y., & Awady, M. K. E. (2018) · Gene · doi:10.1016/j.gene.2018.04.032 · Cited by 17

An ultrasound and histomorphological analysis of experimental liver cirrhosis in rats

Dias, J. V., Paredes, B. D., Mesquita, L. F., Carvalho, A. B., Kozlowski, E. O., Lessa, A. S., Takiya, C. M., Resende, C. M., Coelho, H. S., Campos-de-Carvalho, A. C., et al. (2008) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2008001100008 · Cited by 17

Mechanisms of Metal-Induced Hepatic Inflammation

Subramaniam, N., & Mann, K. K. (2024) · Current Environmental Health Reports · doi:10.1007/s40572-024-00463-6 · Cited by 18

A traditional formula, Chunggan extract, attenuates thioacetamide-induced hepatofibrosis via GSH system in rats

Kwak, K.-G., Wang, J., Shin, J., Lee, D., & Son, C. (2010) · Human & Experimental Toxicology · doi:10.1177/0960327110389502 · Cited by 16

Ligustrazine-Oleanolic Acid Glycine Derivative, G-TOA, Selectively Inhibited the Proliferation and Induced Apoptosis of Activated HSC-T6 Cells

Siling, B., Chu, F., Wang, M., Bi, L., Mao, P., Zhang, H., Wang, P., Guo, W., Xu, L., Ren, L., et al. (2016) · Molecules · doi:10.3390/molecules21111599 · Cited by 16

Direct orthotopic implantation of hepatic organoids

Zhou, V. X., Lolas, M., & Chang, T. T. (2016) · Journal of Surgical Research · doi:10.1016/j.jss.2016.12.028 · Cited by 16

Epigenetic Effects of an Adenosine Derivative in a Wistar Rat Model of Liver Cirrhosis

Rodríguez‐Aguilera, J. R., Guerrero‐Hernández, C., Pérez‐Molina, R., del Castillo, C. E. C., de Vaca, R. P., Guerrero‐Celis, N., Domı́nguez, M., Murillo‐de‐Ozores, A. R., Arzate‐Mejía, R. G., Targa, F. R., et al. (2017) · Journal of Cellular Biochemistry · doi:10.1002/jcb.26192 · Cited by 15

Interferon Lambda and Liver Fibrosis

Eslam, M., Ahlenstiel, G., & George, J. (2019) · Journal of Interferon & Cytokine Research · doi:10.1089/jir.2018.0175 · Cited by 16

Oct4 and Hnf4α-induced hepatic stem cells ameliorate chronic liver injury in liver fibrosis model

Park, M. R., Wong, M. S., Araúzo-Bravo, M. J., Lee, H.-A., Nam, D., Park, S. Y., Seo, H. D., Lee, S. M., Zeilhofer, H. F., Zaehres, H., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0221085 · Cited by 16

Decursin ameliorates carbon-tetrachloride-induced liver fibrosis by facilitating ferroptosis of hepatic stellate cells

Que, R., Cao, M., Dai, Y.-C., Zhou, Y., Chen, Y., & Lin, L. (2022) · Biochemistry and Cell Biology · doi:10.1139/bcb-2022-0027 · Cited by 17

Proteomics in liver fibrosis is more than meets the eye

Cheung, K. J., Tilleman, K., Deforce, D. L. D., Colle, I. O., & Vlierberghe, H. V. (2008) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0b013e3282f4de92 · Cited by 16

Effects of obesity reduction on transient elastography–based parameters in pediatric non-alcoholic fatty liver disease

Isoura, Y., Cho, Y., Fujimoto, H., Hamazaki, T., & Tokuhara, D. (2020) · Obesity Research & Clinical Practice · doi:10.1016/j.orcp.2020.08.005 · Cited by 16

Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration

Arnold, F., Mahaddalkar, P. U., Kraus, J. M., Zhong, X., Bergmann, W., Srinivasan, D., Gout, J., Roger, E., Beutel, A. K., Zizer, E., et al. (2021) · Advanced Science · doi:10.1002/advs.202100626 · Cited by 18

Infiltrating monocytes versus resident kupffer cells: Do alternatively activated macrophages need to be targeted alternatively?

Tacke, F., Kurts, C., Kowdley, K. V., McCaughan, G. W., & Trautwein, C. (2010) · Hepatology · doi:10.1002/hep.24714 · Cited by 15

SHSST Cyclodextrin Complex Prevents the Fibrosis Effect on CCl4-Induced Cirrhotic Cardiomyopathy in Rats through TGF-β Pathway Inhibition Effects

Yang, C.-H., Ting, W., Day, C. H., Ju, D., Yeh, Y., Chung, L.-C., Tsai, F.-J., Tsai, C., Tsai, Y., & Huang, C. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms15058037 · Cited by 15

Effects of Liver Fibrosis Progression on Tissue Relaxation Times in Different Mouse Models Assessed by Ultrahigh Field Magnetic Resonance Imaging

Müller, A., Hochrath, K., Stroeder, J., Hittatiya, K., Schneider, G. K., Lammert, F., Buecker, A., & Fries, P. (2017) · BioMed Research International · doi:10.1155/2017/8720367 · Cited by 15

Engineering and Monitoring 3D Cell Constructs with Time-Evolving Viscoelasticity for the Study of Liver Fibrosis In Vitro

Cacopardo, L., & Ahluwalia, A. D. (2021) · Bioengineering · doi:10.3390/bioengineering8080106 · Cited by 15

Design and Discovery of Some Novel Chalcones as Antioxidant and Anti‐Inflammatory Agents via Attenuating NF‐κB

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A murine model demonstrating reversal of structural and functional correlates of cirrhosis with progenitor cell transplantation

Muthiah, M. D., Huang, D. Q., Zhou, L., Jumat, N. H., Choolani, M., Chan, J. K. Y., Wee, A., Lim, S. G., & Dan, Y.-Y. (2019) · Scientific Reports · doi:10.1038/s41598-019-51189-7 · Cited by 15

Are we any closer to treating liver fibrosis (and if no, why not)?

Feng, R., Yuan, X., Shao, C., Ding, H., Liebe, R., & Weng, H. (2018) · Journal of Digestive Diseases · doi:10.1111/1751-2980.12584 · Cited by 14

Novel potential biomarkers for severe alcoholic liver disease

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Key regulators of hepatic stellate cell activation in alcohol liver Disease: A comprehensive review

Patidar, P., Hirani, N., Bharti, S., & Baig, M. S. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.112938 · Cited by 16

Hepatic Stellate Cell Membrane-Camouflaged Nanoparticles for Targeted Delivery of an Antifibrotic Agent to Hepatic Stellate Cells with Enhanced Antifibrosis Efficacy

Cheng, Z., Li, F., Qie, Y., Sun, J., Wang, Y., Zhao, Y., & Nie, G. (2024) · Nano Letters · doi:10.1021/acs.nanolett.4c04820 · Cited by 19

Expression of pro-fibrotic and anti-fibrotic molecules in dimethylnitrosamine-induced hepatic fibrosis

Sferra, R., Vetuschi, A., Pompili, S., Gaudio, E., Speca, S., & Latella, G. (2016) · Pathology - Research and Practice · doi:10.1016/j.prp.2016.11.004 · Cited by 14

Noninvasive evaluation of liver fibrosis: comparison of the stretched exponential diffusion-weighted model to other diffusion-weighted MRI models and transient elastography

Park, J. H., Seo, N., Chung, Y. E., Kim, S. U., Park, Y. N., Choi, J., Park, M., & Kim, M. (2021) · European Radiology · doi:10.1007/s00330-020-07600-3 · Cited by 14

Fibroblast growth factor receptor 3 in hepatocytes protects from toxin-induced liver injury and fibrosis

Fearon, A. E., Slabber, C. F., Kuklin, A., Bachofner, M., Tortola, L., Pohlmeier, L. M., Pantasis, S., Hornemann, T., Chen, L., Köpf, M., et al. (2021) · iScience · doi:10.1016/j.isci.2021.103143 · Cited by 14

Hepatic Tissue Engineering

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Activin A in Nonalcoholic Fatty Liver Disease

Yndestad, A., Haukeland, J. W., Dahl, T. B., Halvorsen, B. L., & Aukrust, P. (2011) · Vitamins and hormones · doi:10.1016/b978-0-12-385961-7.00015-9 · Cited by 14

Protective Effects of Curcumin and Ginger on Liver Cirrhosis Induced by Carbon Tetrachloride in Rats

Abd-Allah, G., Elbakry, K., Bahnasawy, M. H., & El-Khodary, E.-S. R. (2016) · International Journal of Pharmacology · doi:10.3923/ijp.2016.361.369 · Cited by 14

A New Mouse Model That Spontaneously Develops Chronic Liver Inflammation and Fibrosis

Fransén-Pettersson, N., Duarte, N., Nilsson, J., Lundholm, M., Mayans, S., Larefalk, Å., Hannibal, T. D., Hansen, L., Schmidt-Christensen, A., Ivars, F., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0159850 · Cited by 14

Altered factor VII activating protease expression in murine hepatic fibrosis and its influence on hepatic stellate cells

Roderfeld, M., Weiskirchen, R., Atanasova, S., Gressner, A. M., Preissner, K. T., Roeb, E., & Kanse, S. M. (2009) · Liver International · doi:10.1111/j.1478-3231.2008.01897.x · Cited by 14

Substrate-specific gene expression profiles in different kidney cell types are associated with Fabry disease

SHIN, Y.-J., Jeon, Y. J., Jung, N., Park, J., Park, H., & Jung, S. (2015) · Molecular Medicine Reports · doi:10.3892/mmr.2015.4010 · Cited by 14

Circulating Elastin Fragments Are Not Affected by Hepatic, Renal and Hemodynamic Changes, But Reflect Survival in Cirrhosis with TIPS

Nielsen, M. J., Lehmann, J., Leeming, D. J., Schierwagen, R., Klein, S., Jansen, C., Strassburg, C. P., Bendtsen, F., Møller, S., Sauerbruch, T., et al. (2015) · Digestive Diseases and Sciences · doi:10.1007/s10620-015-3783-9 · Cited by 14

Histone lactylation-augmented IRF4 is implicated in arsenite-induced liver fibrosis via modulating Th17 cell differentiation

Chen, W., Wang, P., Xie, Y. H., Xie, D., Wang, H., Bu, N., Lin, J., Wu, M., Xia, H., Cheng, C., et al. (2025) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2025.111507 · Cited by 13

Expression of Syndecan-1 in Chronic Liver Diseases: Correlation With Hepatic Fibrosis

Charchanti, A. V., Kanavaros, P., Koniaris, E., Kataki, A., Glantzounis, G. K., Agnantis, N. J., & GOUSSIA, A. C. (2021) · In Vivo · doi:10.21873/invivo.12264 · Cited by 14

Enzymatically-epoxidized docosahexaenoic acid, 19,20-EpDPE, suppresses hepatic crown-like structure formation and nonalcoholic steatohepatitis fibrosis through GPR120

Aoki, H., Isobe, Y., Yoshida, M., Kang, J. X., Maekawa, M., & Arita, M. (2022) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2022.159275 · Cited by 14

Exploring hepatic fibrosis screening via deep learning analysis of tongue images

Lu, X.-Z., Hu, H.-T., Li, W., Deng, J., Chen, L., Cheng, M., Huang, H., Ke, W.-P., Wang, W., & Sun, B. (2024) · Journal of Traditional and Complementary Medicine · doi:10.1016/j.jtcme.2024.03.010 · Cited by 13

Hedgehog signaling is a promising target for the treatment of hepatic fibrogenesis: a new management strategy using itraconazole-loaded nanoparticles

Elmorsy, E. A., Saber, S., Kira, A. Y., Alghasham, A., Abdel-Hamed, M. R., Amer, M. M., Mohamed, E. A. K., Ali, A., Alkhamiss, A. S., Hamad, R. S., et al. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1377980 · Cited by 13

Assessing the combined impact of fatty liver-induced TGF-β1 and LPS-activated macrophages in fibrosis through a novel 3D serial section methodology

Ishiyama, S., Hayatsu, M., Toriumi, T., Tsuda, H., Watanabe, K., Kasai, H., Kishigami, S., Mochizuki, K., & Mikami, Y. (2024) · Scientific Reports · doi:10.1038/s41598-024-60845-6 · Cited by 14

Hydronidone induces apoptosis in activated hepatic stellate cells through endoplasmic reticulum stress‐associated mitochondrial apoptotic pathway

Sun, Z., Guo, Y., Xu, X., Zhou, C. L., Luo, X., Shen, Z., Shen, B., Wang, J., Lu, J., Zhang, Q., et al. (2024) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.16635 · Cited by 14

Liver-targeted delivery based on prodrug: passive and active approaches

Chen, J., Yao, Y., Mao, X., Chen, Y., & Ni, F. (2024) · Journal of drug targeting · doi:10.1080/1061186x.2024.2386416 · Cited by 13

Bone marrow cell transplantation is associated with fibrogenic cells apoptosis during hepatic regeneration in cholestatic rats

de Carvalho, S. N., Lira, D. D. C., Cortez, E. A. C., de Andrade, D. C., Thole, A. A., Stumbo, A. C., & de Carvalho, L. (2012) · Biochemistry and Cell Biology · doi:10.1139/bcb-2012-0045 · Cited by 13

Polaprezinc inhibits liver fibrosis and proliferation in hepatocellular carcinoma

Ye, J., Zhang, Z., Zhu, L. W., Lu, M., Li, Y., Zhou, J., Lu, X., & Du, Q. (2017) · Molecular Medicine Reports · doi:10.3892/mmr.2017.7262 · Cited by 13

Stevia prevents experimental cirrhosis by reducing hepatic myofibroblasts and modulating molecular profibrotic pathways

Ramos‐Tovar, E., Buendía‐Montaño, L. D., Galindo‐Gómez, S., Hernández‐Aquino, E., Tsutsumi, V., & Muriel, P. (2018) · Hepatology Research · doi:10.1111/hepr.13275 · Cited by 13

The miR‐455‐3p/HDAC2 axis plays a pivotal role in the progression and reversal of liver fibrosis and is regulated by epigenetics

You, H., Wang, L., Bu, F., Meng, H., Pan, X., Li, J., Zhang, Y., Wang, A., Yin, N., Huang, C. Z., et al. (2021) · The FASEB Journal · doi:10.1096/fj.202002319rrr · Cited by 12

Beneficial Effects of a Curcumin Derivative and Transforming Growth Factor-β Receptor I Inhibitor Combination on Nonalcoholic Steatohepatitis

Ha, K. B., Lee, E. S., Park, N. W., Jo, S. H., Shim, S., Kim, D., Ahn, C. M., & Chung, C. H. (2023) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2022.0110 · Cited by 13

Pathophysiologie der Leberfibrose

Tacke, F., & Weiskirchen, R. (2009) · Der Internist · doi:10.1007/s00108-009-2419-6 · Cited by 14

Hepatocyte IKK2 Protects Mdr2−/− Mice from Chronic Liver Failure

Ehlken, H., Kondylis, V., Heinrichsdorff, J., Ochoa‐Callejero, L., Roskams, T., & Pasparakis, M. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025942 · Cited by 13

Republished: Non-alcoholic fatty liver disease: non-invasive investigation and risk stratification

Dyson, J. K., McPherson, S., & Anstee, Q. M. (2014) · Postgraduate Medical Journal · doi:10.1136/postgradmedj-2013-201620rep · Cited by 13

Hepatic Fibrosis and Cirrhosis

Rockey, D. C., & Friedman, S. L. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4377-0881-3.00005-x · Cited by 13

Pentoxifylline inhibits liver fibrosis via hedgehog signaling pathway

Li, H., Hua, J., Guo, C., Wang, W., Wang, B., Yang, D., Wei, P., & Lu, Y. (2016) · Journal of Huazhong University of Science and Technology [Medical Sciences] · doi:10.1007/s11596-016-1594-7 · Cited by 13

Retinol dehydrogenase 13 deficiency diminishes carbon tetrachloride-induced liver fibrosis in mice

Cui, X., Dang, S., Wang, Y., Chen, Y., Zhou, J., Shen, C., Kuang, Y., Fei, J., Lu, L., & Wang, Z. (2016) · Toxicology Letters · doi:10.1016/j.toxlet.2016.11.010 · Cited by 13

Biliary System Architecture: Experimental Models and Visualization Techniques

Sarnová, L., & Gregor, M. (2017) · Physiological Research · doi:10.33549/physiolres.933499 · Cited by 11

Proteomics reveals acute pro‐inflammatory and protective responses in rat Kupffer cells and hepatocytes after chemical initiation of liver cancer and after LPS and IL‐6

Lorenz, O., Parzefall, W., Kainzbauer, E., Wimmer, H., Grasl‐Kraupp, B., Gerner, C., & Schulte‐Hermann, R. (2009) · PROTEOMICS - CLINICAL APPLICATIONS · doi:10.1002/prca.200800173 · Cited by 13

Suppressive Effect of Orthovanadate on Hepatic Stellate Cell Activation and Liver Fibrosis in Rats

Nishikawa, Y., Ohi, N., Yagisawa, A., Doi, Y., Yamamoto, Y., Yoshida, M., Tokairin, T., Yoshioka, T., Omori, Y., & Enomoto, K. (2009) · American Journal Of Pathology · doi:10.2353/ajpath.2009.080261 · Cited by 13

“Kupffer Cell Teleportation” Strategy for Liver Fibrosis Alleviation Based on Hybrid Polymer‐ Bimetallic Sequential Delivery System

Qiu, Z., Milichko, V. A., Zhou, Y., Jing, H., Lü, Q., Wang, H., Kang, B., Wang, X., & Li, N. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202309690 · Cited by 15

Linking fatty liver diseases to hepatocellular carcinoma by hepatic stellate cells

Chen, L., Ye, X.-S., Yang, L., Zhao, J., You, J., & Feng, Y. (2024) · Journal of the National Cancer Center · doi:10.1016/j.jncc.2024.01.002 · Cited by 12

Total flavonoids of litchi Seed alleviates schistosomiasis liver fibrosis in mice by suppressing hepatic stellate cells activation and modulating the gut microbiomes

Li, Q., Wang, J., Lv, J., Liu, D., Xiao, S., Mo, J., Zuo-chao, L., Qiu, R., Li, C., Tang, L., et al. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117240 · Cited by 12

Recent updates in applications of nanomedicine for the treatment of hepatic fibrosis

Setyawati, D. R., Sekaringtyas, F. C., Pratiwi, R. D., Rosyidah, A., Azhar, R., Gustini, N., Syahputra, G., Rosidah, I., Mardliyati, E., Tarwadi, et al. (2024) · Beilstein Journal of Nanotechnology · doi:10.3762/bjnano.15.89 · Cited by 14

Hepatitis C virus RNA replication in human stellate cells regulates gene expression of extracellular matrix-related molecules

Watanabe, N., Aizaki, H., Matsuura, T., Kojima, S., Wakita, T., & Suzuki, T. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.02.125 · Cited by 12

Multi-cellular transitional organotypic models to investigate liver fibrosis

Orbach, S. M., Ford, A. J., Saverot, S.-E., & Rajagopalan, P. (2018) · Acta Biomaterialia · doi:10.1016/j.actbio.2018.10.010 · Cited by 12

Rat multicellular 3D liver microtissues to explore TGF-β1 induced effects

Prestigiacomo, V., Weston, A. A., & Suter‐Dick, L. (2019) · Journal of Pharmacological and Toxicological Methods · doi:10.1016/j.vascn.2019.106650 · Cited by 13

Preliminary Clinical Experience with Shear Wave Dispersion Imaging for Liver Viscosity in Preoperative Diagnosis of Focal Liver Lesions

Dong, Y., Qiu, Y., Zhang, Q., Yang, D., Yu, L., Wang, W., & Dietrich, C. F. (2020) · Zeitschrift für Gastroenterologie · doi:10.1055/a-1217-7465 · Cited by 12

6-Shogaol alleviates CCl4-induced liver fibrosis by attenuating inflammatory response in mice through the NF-κB pathway

Qiu, J., Chai, Y.-N., Duan, F.-Y., Zhang, H., Han, X.-Y., Chen, L., & Duan, F. (2022) · Acta Biochimica Polonica · doi:10.18388/abp.2020_5802 · Cited by 13

DHEA and Its Metabolites Reduce the Cytokines Involved in the Inflammatory Response and Fibrosis in Primary Biliary Cholangitis

Blatkiewicz, M., Sielatycka, K., Piotrowska, K., & Kilańczyk, E. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065301 · Cited by 11

Copper-induced hepatitis: the COMMD1 deficient dog as a translational animal model for human chronic hepatitis

Favier, R. P., Spee, B., Penning, L. C., & Rothuizen, J. J. (2011) · Veterinary Quarterly · doi:10.1080/01652176.2011.563146 · Cited by 13

Frequency and Phenotype of Human Circulating and Intrahepatic Natural Killer Cell Subsets Is Differentially Regulated according to Stage of Chronic Liver Disease

Zimmermann, H. W., Mueller, J. R., Seidler, S., Luedde, T., Trautwein, C., & Tacke, F. (2013) · Digestion · doi:10.1159/000350821 · Cited by 12

Cyclosporine Inhibits Profibrotic Effects of Interleukin-4 and Transforming Growth Factor β on Human Intrahepatic Fibroblasts Cultured In Vitro

Pissaia, A., Aoudjehane, L., Othman, S. B., Scatton, O., Soubrane, O., Housset, C., Calmus, Y., & Conti, F. (2010) · Transplantation Proceedings · doi:10.1016/j.transproceed.2010.09.124 · Cited by 12

The biological response modifier AM3 attenuates the inflammatory cell response and hepatic fibrosis in rats with biliary cirrhosis

Albillos, A., Nieto, M., Cantera, M., Muñoz, L., Fraile, B., Reyes, E., Lledó, L., Blanco, I., Pastor, Ó., Salas, C., et al. (2010) · Gut · doi:10.1136/gut.2008.168831 · Cited by 12

Loss of steroid receptor co-activator-3 attenuates carbon tetrachloride-induced murine hepatic injury and fibrosis

Ma, X., Xu, L., Shu, W., Chen, H., Xu, J., Li, X., & Ning, G. (2009) · Laboratory Investigation · doi:10.1038/labinvest.2009.51 · Cited by 12

Splanchnic Th2 and Th1 Cytokine Redistribution in Microsurgical Cholestatic Rats

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Diethylcarbamazine attenuates the expression of pro-fibrogenic markers and hepatic stellate cells activation in carbon tetrachloride-induced liver fibrosis

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Simultaneous evaluation of perfusion and morphology using GRASP MRI in hepatic fibrosis

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Cationized ferritin as a magnetic resonance imaging probe to detect microstructural changes in a rat model of non‐alcoholic steatohepatitis

Beeman, S. C., Mandarino, L. J., Georges, J., & Bennett, K. M. (2013) · Magnetic Resonance in Medicine · doi:10.1002/mrm.24619 · Cited by 12

MicroRNA29a Reverts the Activated Hepatic Stellate Cells in the Regression of Hepatic Fibrosis through Regulation of ATPase H+ Transporting V1 Subunit C1

Jing, F., Geng, Y., Xu, X., Xu, H., Shi, J., & Xu, Z. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20040796 · Cited by 12

A mechanism for the anti-fibrogenic effects of the pregnane X receptor (PXR) in the liver: Inhibition of NF-κB?

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Suppressed Histone H3 Lysine 18 Acetylation Is Involved in Arsenic-Induced Liver Fibrosis in Rats by Triggering the Dedifferentiation of Liver Sinusoidal Endothelial Cells

Hu, F., Zhou, X., Peng, Q., & Ma, L. (2023) · Toxics · doi:10.3390/toxics11110928 · Cited by 11

Emerging roles of cuproptosis in liver diseases

Yang, Q., Liu, X., Tang, H., Chen, Y., & Li, B. (2025) · Digestive and Liver Disease · doi:10.1016/j.dld.2025.04.011 · Cited by 11

Laser fluorescence spectroscopy and optical tissue oximetry in the diagnosis of skin fibrosis

Chursinova, Y. V., Куликов, Д. А., Рогаткин, Д. А., Raznitsyna, I. A., Mosalskaya, D. V., Bobrov, M. A., Николаевна, П. Е., & Molochkov, A. V. (2019) · Biomedical Photonics · doi:10.24931/2413-9432-2019-8-1-38-45 · Cited by 12

Models and Mechanisms of Fibrosis Resolution

Snowdon, V., & Fallowfield, J. A. (2011) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2010.01400.x · Cited by 35

Defining therapeutic targets for liver fibrosis: Exploiting the biology of inflammation and repair

Iredale, J. P. (2008) · Pharmacological Research · doi:10.1016/j.phrs.2008.06.011 · Cited by 80

Animal and Organoid Models of Liver Fibrosis

Bao, Y., Wang, L., Pan, H., Zhang, T.-R., Chen, Y., Xu, S.-J., Mao, X., & Li, S.-W. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.666138 · Cited by 101

Liver fibrosis: a bidirectional model of fibrogenesis and resolution

Ramachandran, P., & Iredale, J. P. (2012) · QJM · doi:10.1093/qjmed/hcs069 · Cited by 113

Leptin and liver tissue repair: Do rodent models provide the answers?

Marra, F. (2006) · Journal of Hepatology · doi:10.1016/j.jhep.2006.10.002 · Cited by 38