A Foxo/Notch pathway controls myogenic differentiation and fiber type specification

Calcium's Role in Mechanotransduction during Muscle Development

Damm, T. B., & Egli, M. (2014) · Cellular Physiology and Biochemistry · doi:10.1159/000356667 · Cited by 14,552

Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α

Lagouge, M., Argmann, C., Gerhart-Hines, Z., Meziane, H., Lerin, C., Daussin, F., Messadeq, N., Milne, J., Lambert, P., Elliott, P., et al. (2006) · Cell · doi:10.1016/j.cell.2006.11.013 · Cited by 4,057

Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres

Lin, J., Wu, H., Tarr, P. T., Zhang, C.-Y., Wu, Z., Boss, O., Michael, L. F., Puigserver, P., Isotani, E., Olson, E. N., et al. (2002) · Nature · doi:10.1038/nature00904 · Cited by 2,546

FoxOs Are Critical Mediators of Hematopoietic Stem Cell Resistance to Physiologic Oxidative Stress

Tothova, Z., Kollipara, R., Huntly, B. J., Lee, B. H., Castrillon, D. H., Cullen, D. E., McDowell, E. P., Lazo-Kallanian, S., Williams, I. R., Sears, C., et al. (2007) · Cell · doi:10.1016/j.cell.2007.01.003 · Cited by 1,562

Molecular diversity of myofibrillar proteins: gene regulation and functional significance

Schiaffino, S., & Reggiani, C. (1996) · Physiological Reviews · doi:10.1152/physrev.1996.76.2.371 · Cited by 1,545

Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction

Puigserver, P., Rhee, J., Donovan, J., Walkey, C. J., Yoon, J. C., Oriente, F., Kitamura, Y., Altomonte, J., Dong, H., Accili, D., et al. (2003) · Nature · doi:10.1038/nature01667 · Cited by 1,487

Untitled work

(2004) · doi:10.1016/s0092-8674(04)00452-0 · Cited by 1,356

Control of endodermal endocrine development by Hes-1

Jensen, J. N., Pedersen, E. E., Galante, P. E., Hald, J., Heller, R. S., Ishibashi, M., Kageyama, R., Guillemot, F., Serup, P., & Madsen, O. D. (2000) · Nature Genetics · doi:10.1038/71657 · Cited by 1,155

Notch signaling is essential for vascular morphogenesis in micePreprint

Krebs, L. T., Xue, Y., Norton, C. R., Shutter, J. R., Maguire, M., Sundberg, J. P., Gallahan, D., Closson, V., Kitajewski, J., Callahan, R., et al. (2000) · Genes & Development · doi:10.1101/gad.14.11.1343 · Cited by 1,065

FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis

Paik, J.-H., Kollipara, R., Chu, G., Ji, H., Xiao, Y., Ding, Z., Miao, L., Tothova, Z., Horner, J. W., Carrasco, D. R., et al. (2007) · Cell · doi:10.1016/j.cell.2006.12.029 · Cited by 1,032

Tissue-Specific Metabolic Regulation of FOXO-Binding Protein: FOXO Does Not Act Alone

Kodani, N., & Nakae, J. (2020) · Cells · doi:10.3390/cells9030702 · Cited by 64

Stem cells, angiogenesis and muscle healing: a potential role in massage therapies?

Best, T. M., Gharaibeh, B., & Huard, J. (2012) · British Journal of Sports Medicine · doi:10.1136/bjsports-2012-091685 · Cited by 59

Defining Akt actions in muscle differentiation

Gardner, S., Anguiano, M., & Rotwein, P. S. (2012) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00259.2012 · Cited by 58

FoxO1 regulates muscle fiber-type specification and inhibits calcineurin signaling during C2C12 myoblast differentiation

Yuan, Y., Shi, X., Liu, Y., & Yang, G.-S. (2010) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-010-0640-1 · Cited by 59

Comparative transcriptome profiling of longissimus muscle tissues from Qianhua Mutton Merino and Small Tail Han sheep

Sun, L., Bai, M., Xiang, L., Zhang, G., Ma, W., & Jiang, H. (2016) · Scientific Reports · doi:10.1038/srep33586 · Cited by 59

Forkhead Box Protein O1 Negatively Regulates Skeletal Myocyte Differentiation through Degradation of Mammalian Target of Rapamycin Pathway Components

Wu, A.-L., Kim, J., Zhang, C., Unterman, T. G., & Chen, J. (2007) · Endocrinology · doi:10.1210/en.2007-1470 · Cited by 58

Forkhead factor FoxO1 is essential for placental morphogenesis in the developing embryo

Ferdous, A., Morris, J. A., Abedin, M. J., Collins, S. C., Richardson, J. A., & Hill, J. A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1107341108 · Cited by 57

Effect of forkhead box O1 (FOXO1) on beta cell development in the human fetal pancreas

Al‐Masri, M., Krishnamurthy, M., Li, J., Fellows, G. F., Dong, H. H., Goodyer, C. G., & Wang, R. (2009) · Diabetologia · doi:10.1007/s00125-009-1632-0 · Cited by 56

Hypoxic Signaling in Skeletal Muscle Maintenance and Regeneration: A Systematic Review

Pircher, T., Wackerhage, H., Aszódi, A., Kammerlander, C., Böcker, W., & Saller, M. M. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.684899 · Cited by 57

Regulation of Pancreatic Juxtaductal Endocrine Cell Formation by FoxO1

Kitamura, T., Kitamura, Y., Kobayashi, M., Kikuchi, O., Sasaki, T., DePinho, R. A., & Accili, D. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.01622-08 · Cited by 53

Insulin Action Research and the Future of Diabetes Treatment: The 2017 Banting Medal for Scientific Achievement Lecture

Accili, D. (2018) · Diabetes · doi:10.2337/dbi18-0025 · Cited by 52

Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition

Günschmann, C., Stachelscheid, H., Akyüz, M. D., Schmitz, A., Missero, C., Brüning, J. C., & Niessen, C. M. (2013) · Developmental Cell · doi:10.1016/j.devcel.2013.05.017 · Cited by 53

The impact of FOXO-1 to cardiac pathology in diabetes mellitus and diabetes-related metabolic abnormalities

Chistiakov, D. A., Orekhov, A. N., & Bobryshev, Y. V. (2017) · International Journal of Cardiology · doi:10.1016/j.ijcard.2017.07.096 · Cited by 52

Multifaceted functions of the forkhead box transcription factors FoxO1 and FoxO3 in skin

Tsitsipatis, D., Klotz, L., & Steinbrenner, H. (2017) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2017.02.027 · Cited by 46

Forkhead BoxO transcription factors restrain exercise‐induced angiogenesis

Slopack, D., Roudier, E. A., Liu, S. T. K., Nwadozi, E., Birot, O., & Haas, T. L. (2014) · The Journal of Physiology · doi:10.1113/jphysiol.2014.275867 · Cited by 48

Metabolic Regulation of Stem Cells and Differentiation: A Forkhead Box O Transcription Factor Perspective

Ludikhuize, M. C., & Colman, M. J. R. (2020) · Antioxidants and Redox Signaling · doi:10.1089/ars.2020.8126 · Cited by 45

The Effects of Muscle Cell Aging on Myogenesis

Moustogiannis, A., Philippou, Α., Taso, O. S., Zevolis, E., Pappa, M. B., Chatzigeorgiou, A., & Koutsilieris, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22073721 · Cited by 45

Molecular mechanisms underlying the effects of cyclosporin A and sirolimus on glucose and lipid metabolism in liver, skeletal muscle and adipose tissue in an in vivo rat model

Fuhrmann, A., Lopes, P., Sereno, J., Pedro, J., Espinoza, D., Pereira, M. J., Reis, F., Eriksson, J. W., & Carvalho, E. (2014) · Biochemical Pharmacology · doi:10.1016/j.bcp.2014.01.020 · Cited by 45

Legacy Effect of Foxo1 in Pancreatic Endocrine Progenitors on Adult β-Cell Mass and Function

Talchai, S. C., & Accili, D. (2015) · Diabetes · doi:10.2337/db14-1696 · Cited by 41

Reciprocal Regulation of Notch and Nuclear Factor of Activated T-cells (NFAT) c1 Transactivation in Osteoblasts

Zanotti, S., Smerdel‐Ramoya, A., & CANALIS, E. M. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.161893 · Cited by 42

Regulation of myogenesis by environmental hypoxia

Beaudry, M., Hidalgo, M., Launay, T., Bello, V., & Darribère, T. (2016) · Journal of Cell Science · doi:10.1242/jcs.188904 · Cited by 40

Glucosamine-Induced OGT Activation Mediates Glucose Production Through Cleaved Notch1 and FoxO1, Which Coordinately Contributed to the Regulation of Maintenance of Self-Renewal in Mouse Embryonic Stem Cells

Jeon, J. H., Suh, H. N., Kim, M., Ryu, J. M., & Han, H. J. (2014) · Stem Cells and Development · doi:10.1089/scd.2013.0583 · Cited by 40

Modelling the Response of FOXO Transcription Factors to Multiple Post-Translational Modifications Made by Ageing-Related Signalling Pathways

Smith, G. R., & Shanley, D. P. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011092 · Cited by 40

FOXO/Fringe is necessary for maintenance of the germline stem cell niche in response to insulin insufficiency

Yang, S.-A., Wang, W.-D., Chen, C.-T., Tseng, C.-Y., Chen, Y.-N., & Hsu, H.-J. (2013) · Developmental Biology · doi:10.1016/j.ydbio.2013.07.018 · Cited by 37

FoxO1 is required in endothelial but not myocardial cell lineages during cardiovascular development

Sengupta, A., Chakraborty, S., Paik, J., Yutzey, K. E., & Evans‐Anderson, H. J. (2012) · Developmental Dynamics · doi:10.1002/dvdy.23759 · Cited by 38

Geniposide Improves Glucose Homeostasis via Regulating FoxO1/PDK4 in Skeletal Muscle

Yan, L., Pan, H., Zhang, X., Wang, H., Liu, S., Zhang, H., Qian, H., Wang, L., & Ying, H. (2019) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.9b00402 · Cited by 36

Starvation induces FoxO-dependent mitotic-to-endocycle switch pausing during Drosophila oogenesis

Jouandin, P., Ghiglione, C., & Noselli, S. (2014) · Development · doi:10.1242/dev.108399 · Cited by 36

Nuclear factor E2-related factor 2 (NRF2) deficiency accelerates fast fibre type transition in soleus muscle during space flight

Hayashi, T., Kudo, T., Fujita, R., Fujita, S.-I., Tsubouchi, H., Fuseya, S., Suzuki, R., Hamada, M., Okada, R., Muratani, M., et al. (2021) · Communications Biology · doi:10.1038/s42003-021-02334-4 · Cited by 35

A Mutant Allele Encoding DNA Binding–Deficient FoxO1 Differentially Regulates Hepatic Glucose and Lipid Metabolism

Cook, J. R., Matsumoto, M., Banks, A. S., Kitamura, T., Tsuchiya, K., & Accili, D. (2015) · Diabetes · doi:10.2337/db14-1506 · Cited by 35

Hyperactive FOXO1 results in lack of tip stalk identity and deficient microvascular regeneration during kidney injury

Dang, L. T. H., Aburatani, T., Marsh, G. A., Johnson, B. G., Alimperti, S., Yoon, C. J., Huang, A., Szak, S. T., Nakagawa, N., Gomez, I. G., et al. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2017.07.010 · Cited by 34

Transcriptome profiling of longissimus thoracis muscles identifies highly connected differentially expressed genes in meat type sheep of India

Arora, R., Naveen Kumar, S., Sudarshan, S., Fairoze, M. N., Kaur, M., Sharma, A., Girdhar, Y., Sreesujatha, R. M., Devatkal, S. K., Ahlawat, S., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0217461 · Cited by 34

Transcriptional Characteristics Showed That miR-144-y/FOXO3 Participates in Embryonic Skin and Feather Follicle Development in Zhedong White Goose

Mabrouk, I., Zhou, Y., Wang, S., Song, Y., Fu, X., Xu, X., Liu, T., Wang, Y., Feng, Z., Fu, J., et al. (2022) · Animals · doi:10.3390/ani12162099 · Cited by 33

Stem cell maintenance in the adult mammalian hippocampus: A matter of signal integration?

Schwarz, T. J., Ebert, B., & Lie, D. C. (2012) · Developmental Neurobiology · doi:10.1002/dneu.22026 · Cited by 34

FoxOs in neural stem cell fate decision

Ro, S., Liu, D., Yeo, H., & Paik, J. (2012) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2012.07.017 · Cited by 36

Notch1-mediated signaling regulates proliferation of porcine satellite cells (PSCs)

Qin, L., Xu, J., Wu, Z., Zhang, Z., Li, J., Wang, C., & Long, Q. (2012) · Cellular Signalling · doi:10.1016/j.cellsig.2012.11.003 · Cited by 32

Muscle development and obesity

Maltin, C. A. (2008) · Organogenesis · doi:10.4161/org.4.3.6312 · Cited by 34

Slow-Myofiber Commitment by Semaphorin 3A Secreted from Myogenic Stem Cells

Tatsumi, R., Suzuki, T., Do, M. Q., Ohya, Y., Anderson, J. E., Shibata, A., Kawaguchi, M., Ohya, S., Ohtsubo, H., Mizunoya, W., et al. (2017) · Stem Cells · doi:10.1002/stem.2639 · Cited by 32

The Plasticity of Pancreatic β-Cells

Honzawa, N., & Fujimoto, K. (2021) · Metabolites · doi:10.3390/metabo11040218 · Cited by 31

Forkhead family transcription factor FoxO and neural differentiation

Wen, Q., Wang, H., Little, P. J., Quirion, R., & Zheng, W. (2012) · Neurogenetics · doi:10.1007/s10048-012-0320-2 · Cited by 31

Inhibition of Glycogen Synthase Kinase-3β Attenuates Glucocorticoid-Induced Suppression of Myogenic Differentiation In Vitro

Ma, Z., Zhong, Z., Zheng, Z., Shi, X., & Zhang, W. (2014) · PLoS ONE · doi:10.1371/journal.pone.0105528 · Cited by 30

FOXO3 Mediates Tooth Movement by Regulating Force-Induced Osteogenesis

Jin, A., Hong, Y., Yang, Y., Xu, H., Huang, X., Gao, X., Gong, X., Dai, Q., & Jiang, L. (2021) · Journal of Dental Research · doi:10.1177/00220345211021534 · Cited by 29

Loss of ovarian function in mice results in abrogated skeletal muscle PPARδ and FoxO1-mediated gene expression

Rogers, N. H., Perfield, J. W., Strissel, K. J., Obin, M. S., & Greenberg, A. S. (2009) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.10.072 · Cited by 30

Transcriptional networks that regulate muscle stem cell function

Punch, V. G., Jones, A., & Rudnicki, M. A. (2009) · WIREs Systems Biology and Medicine · doi:10.1002/wsbm.11 · Cited by 29

The Notch intracellular domain represses CRE-dependent transcription

Hallaq, R. Y., Volpicelli, F., Cuchillo‐Ibáñez, I., Hooper, C., Mizuno, K., Uwanogho, D., Čaušević, M., Asuni, A. A., To, A. W. M., Soriano, S., et al. (2014) · Cellular Signalling · doi:10.1016/j.cellsig.2014.11.034 · Cited by 31

Continuous exposure of isoprenaline inhibits myoblast differentiation and fusion through PKA/ERK1/2-FOXO1 signaling pathway

Chen, S., Jing, Y., Zhang, J., Jiang, M., Hu, T.-Q., Leng, W., Li, X., Li, X., Zhang, L., Zheng, F., et al. (2019) · Stem Cell Research & Therapy · doi:10.1186/s13287-019-1160-x · Cited by 29

Pharmacological conversion of gut epithelial cells into insulin-producing cells lowers glycemia in diabetic animals

Du, W. J., Wang, J., Kuo, T., Wang, L., McKimpson, W. M., Son, J., Watanabe, H., Kitamoto, T., Lee, Y., Creusot, R. J., et al. (2022) · Journal of Clinical Investigation · doi:10.1172/jci162720 · Cited by 36

FoxO1 regulates asymmetric dimethylarginine via downregulation of dimethylaminohydrolase 1 in human endothelial cells and subjects with atherosclerosis

Menghini, R., Casagrande, V., Cardellini, M., Ballanti, M., Davato, F., Cardolini, I., Stoehr, R., Fabrizi, M., Morelli, M., Anemona, L., et al. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.07.026 · Cited by 28

MiR-34c represses muscle development by forming a regulatory loop with Notch1

Hou, L., Xu, J., Li, H., Ou, J., Jiao, Y., Hu, C. Y., & Wang, C. (2017) · Scientific Reports · doi:10.1038/s41598-017-09688-y · Cited by 27

Genome-Wide Exploration of miRNA Function in Mammalian Muscle Cell Differentiation

Polesskaya, A., Degerny, C., Pinna, G., Maury, Y., Kratassiouk, G., Mouly, V., Morozova, N., Kropp, J., Frandsen, N., & Harel‐Bellan, A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0071927 · Cited by 28

Mechanistic regulation of FOXO transcription factors in the nucleus

Guo, X., Peng, K., He, Y., & Xue, L. (2024) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2024.189083 · Cited by 26

FoxO1 Gain of Function in the Pancreas Causes Glucose Intolerance, Polycystic Pancreas, and Islet Hypervascularization

Kikuchi, O., Kobayashi, M., Amano, K., Sasaki, T., Kitazumi, T., Kim, H.-J., Lee, Y., Yokota‐Hashimoto, H., Kitamura, Y.-I., & Kitamura, T. (2012) · PLoS ONE · doi:10.1371/journal.pone.0032249 · Cited by 28

Blunted Refeeding Response and Increased Locomotor Activity in Mice Lacking FoxO1 in Synapsin-Cre–Expressing Neurons

Ren, H., Plum‐Mörschel, L., Juárez, R. G., Lu, T. Y., Kim-Muller, J. Y., Heinrich, G., Wardlaw, S. L., Silver, R., & Accili, D. (2013) · Diabetes · doi:10.2337/db13-0597 · Cited by 25

Oncogenic RAS-induced CK1α drives nuclear FOXO proteolysis

Zhang, F., Virshup, D. M., & Cheong, J. K. (2017) · Oncogene · doi:10.1038/onc.2017.334 · Cited by 24

Single nucleotide polymorphisms associated with growth traits in Jinghai yellow chickens

Abdalhag, M. A., Zhang, T., Fan, Q. C., Zhang, X., Zhang, G. X., Wang, J. Y., Wei, Y., & Wang, Y. J. (2015) · Genetics and Molecular Research · doi:10.4238/2015.december.8.6 · Cited by 24

Caveolin-1 is down-regulated in alveolar rhabdomyosarcomas and negatively regulates tumor growth

Huertas-Martínez, J., Rello‐Varona, S., Herrero‐Martín, D., Barrau, I., García-Monclús, S., Sáinz‐Jaspeado, M., Lagares‐Tena, L., Núñez‐Álvarez, Y., Mateo‐Lozano, S., Mora, J., et al. (2014) · Oncotarget · doi:10.18632/oncotarget.2403 · Cited by 23

Role and Therapeutic Potential of the Pro-Longevity Factor FOXO and Its Regulators in Neurodegenerative Disease

Néri, C. (2012) · Frontiers in Pharmacology · doi:10.3389/fphar.2012.00015 · Cited by 26

Foxo1 Is Required for Normal Somatotrope Differentiation

Kapali, J., Kabat, B. E., Schmidt, K. L., Stallings, C. E., Tippy, M. D., Jung, D. O., Edwards, B. S., Nantie, L. B., Raeztman, L. T., Navratil, A. M., et al. (2016) · Endocrinology · doi:10.1210/en.2016-1372 · Cited by 23

WNK1 regulates skeletal muscle cell hypertrophy by modulating the nuclear localization and transcriptional activity of FOXO4

Mandai, S., Mori, T., Nomura, N., Furusho, T., Arai, Y., Kikuchi, H., Sasaki, E., Sohara, E., Rai, T., & Uchida, S. (2018) · Scientific Reports · doi:10.1038/s41598-018-27414-0 · Cited by 23

Constitutive Expression of Insulin Receptor Substrate (IRS)-1 Inhibits Myogenic Differentiation through Nuclear Exclusion of Foxo1 in L6 Myoblasts

Hakuno, F., Yamauchi, Y., Kaneko, G., Yoneyama, Y., Nakae, J., Chida, K., Kadowaki, T., Yamanouchi, K., Nishihara, M., & Takahashi, S. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025655 · Cited by 21

Characterization of Optimal Strain, Frequency and Duration of Mechanical Loading on Skeletal Myotubes' Biological Responses

Moustogiannis, A., Philippou, Α., Zevolis, E., Taso, O. S., Chatzigeorgiou, A., & Koutsilieris, M. (2020) · In Vivo · doi:10.21873/invivo.11972 · Cited by 22

Bach1 promotes muscle regeneration through repressing Smad-mediated inhibition of myoblast differentiation

Suzuki, K., Matsumoto, M., Katoh, Y., Liu, L., Ochiai, K., Aizawa, Y., Nagatomi, R., Okuno, H., Itoi, E., & Igarashi, K. (2020) · PLoS ONE · doi:10.1371/journal.pone.0236781 · Cited by 22

Transferrin receptor 1 plays an important role in muscle development and denervation-induced muscular atrophy

Wu, H.-T., Li, Y., Cheng, J., Yang, H., Chen, L., Liu, F., Wu, Y., & Fan, M. (2020) · Neural Regeneration Research · doi:10.4103/1673-5374.301024 · Cited by 21

Circular RNA screening identifies circMYLK4 as a regulator of fast/slow myofibers in porcine skeletal muscles

Cao, H., Liu, J., Du, T., Liu, Y., Zhang, X., Guo, Y., Wang, J., Zhou, X., Li, X., Yang, G., et al. (2021) · Molecular Genetics and Genomics · doi:10.1007/s00438-021-01835-5 · Cited by 21

Insulin and LiCl Synergistically Rescue Myogenic Differentiation of FoxO1 Over-Expressed Myoblasts

Wu, Y. J., Fang, Y. H., Cheng, H., Chang, L. C., Chung, S. Y., Huang, W., Wang, X. W., Lee, K. W., & Chen, S. L. (2014) · PLoS ONE · doi:10.1371/journal.pone.0088450 · Cited by 20

Ultrafine Particle Exposure Reveals the Importance of FOXO1/Notch Activation Complex for Vascular Regeneration

Baek, K. I., Packard, R. R. S., Hsu, J. J., Saffari, A. A., Ma, Z., Luu, A. P., Pietersen, A., Yen, H., Ren, B., Ding, Y., et al. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7166 · Cited by 20

AKT down-regulates insulin-like growth factor-1 receptor as a negative feedback

Qin, L., Wang, Y., Tao, L., & Wang, Z. (2011) · The Journal of Biochemistry · doi:10.1093/jb/mvr066 · Cited by 19

Circ-HIPK3 plays an active role in regulating myoblast differentiation

Yao, R., Yao, Y., Li, C., Li, X., Ni, W., Quan, R., Liu, L., Li, H., Xu, Y., Zhang, M., et al. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.11.119 · Cited by 19

Reconstitution of Insulin Action in Muscle, White Adipose Tissue, and Brain of Insulin Receptor Knock-out Mice Fails to Rescue Diabetes

Lin, H. V., & Accili, D. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.210807 · Cited by 19

APOE–NOTCH axis governs elastogenesis during human cardiac valve remodeling

Liu, Z., Liu, Y., Yu, Z., Tan, C., Pek, N. M. Q., O’Donnell, A., Wu, A., Glass, I. A., Winlaw, D. S., Guo, M., et al. (2024) · Nature Cardiovascular Research · doi:10.1038/s44161-024-00510-3 · Cited by 18

Expression profile of Notch-1 in mechanically overloaded plantaris muscle of mice

Akiho, M., Nakashima, H., Sakata, M., Yamasa, Y., Yamaguchi, A., & Sakuma, K. (2009) · Life Sciences · doi:10.1016/j.lfs.2009.11.011 · Cited by 18

Reprogramming Cells to Make Insulin

McKimpson, W. M., & Accili, D. (2019) · Journal of the Endocrine Society · doi:10.1210/js.2019-00040 · Cited by 19

Homozygosity for an Allele Encoding Deacetylated FoxO1 Protects Macrophages From Cholesterol-Induced Inflammation Without Increasing Apoptosis

Tsuchiya, K., Banks, A. S., Liang, C.-P., Tabas, I. A., Tall, A. R., & Accili, D. (2011) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.110.219477 · Cited by 18

Hispaglabridin B, a constituent of liquorice identified by a bioinformatics and machine learning approach, relieves protein‐energy wasting by inhibiting forkhead box O1

Huang, Z., Wang, L., Wang, J., Feng, W., Yang, Z., Ni, S.-H., Huang, Y., Li, H., Yang, Y., Wang, M., et al. (2018) · British Journal of Pharmacology · doi:10.1111/bph.14508 · Cited by 18

The role of Notch signaling in diabetic endothelial progenitor cells dysfunction

Sukmawati, D., Tanaka, R., Ito‐Hirano, R., Fujimura, S., Hayashi, A., Itoh, S., Mizuno, H., & Daida, H. (2015) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2015.09.015 · Cited by 17

Myostatin and Related Factors Are Involved in Skeletal Muscle Protein Breakdown in Growing Broilers Exposed to Constant Heat Stress

Li, X., Zhang, M., Feng, J., & Zhou, Y. Q. (2021) · Animals · doi:10.3390/ani11051467 · Cited by 17

Insulin receptor substrate-1 and -2 mediate resistance to glucose-induced caspase-3 activation in human neuroblastoma cells

Stöhr, O., Hahn, J., Moll, L., Leeser, U., Freude, S., Bernard, C., Schilbach, K., Markl, A., Udelhoven, M., Krone, W., et al. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2011.02.006 · Cited by 17

ANGPTL8 reverses established adriamycin cardiomyopathy by stimulating adult cardiac progenitor cells

Chen, S., Chen, J., Meng, X., Shen, J.-S., Huang, J., Huang, P., Pu, Z., McNeill, N. H., & Grayburn, P. A. (2016) · Oncotarget · doi:10.18632/oncotarget.13061 · Cited by 17

Mitochondria define intestinal stem cell differentiation downstream of a FOXO/Notch axisPreprint

Ludikhuize, M. C., Meerlo, M., Pagès-Gallego, M., Julià, M. B., Nguyen, N. B., Brombacher, E. C., Paik, J., Burgering, B. M. T., & Colman, M. J. R. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/777391 · Cited by 17

Functional genomics applications and therapeutic implications in sarcopenia

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Pdcd2l Promotes Palmitate-Induced Pancreatic Beta-Cell Apoptosis as a FoxO1 Target Gene

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Deletion of Pofut1 in Mouse Skeletal Myofibers Induces Muscle Aging-Related Phenotypes in cis and in trans

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Republished: Stem cells, angiogenesis and muscle healing: a potential role in massage therapies?

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Selective repression of Notch pathway target gene transcription

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Hepatic FoxOs link insulin signaling with plasma lipoprotein metabolism through an apolipoprotein M/sphingosine-1-phosphate pathway

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Low-Intensity Exercise Affects Cardiac Fatty Acid Oxidation by Increasing the Nuclear Content of PPARα, FOXO1, and Lipin1 in Fructose-Fed Rats

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Gas7-Deficient Mouse Reveals Roles in Motor Function and Muscle Fiber Composition during Aging

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Bigbelly seahorse (Hippocampus abdominalis)-derived peptides enhance skeletal muscle differentiation and endurance performance via activated P38MAPK/AKT signalling pathway: An in vitro and in vivo analysis

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Skeletal Muscle Dysfunction in Experimental Pulmonary Hypertension

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Forkhead Box O1 Is Present in Quiescent Pituitary Cells during Development and Is Increased in the Absence of p27Kip1

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Forkhead box O proteins: steering the course of stem cell fate

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Interferon Regulatory Factor 6 Promotes Keratinocyte Differentiation in Response to Porphyromonas gingivalis

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Chemical induction of gut β-like-cells by combined FoxO1/Notch inhibition as a glucose-lowering treatment for diabetes

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Dysregulated FOXO1 activity drives skeletal muscle intrinsic dysfunction in amyotrophic lateral sclerosis

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Aminoguanidine hemisulfate improves mitochondrial autophagy, oxidative stress, and muscle force in Duchenne muscular dystrophy via the AKT/FOXO1 pathway in mdx mice

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Neuronal overexpression of insulin receptor substrate 2 leads to increased fat mass, insulin resistance, and glucose intolerance during aging

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The Role of Hypoxia and Hypoxia Signaling in Skeletal Muscle Physiology

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Mechanisms Underlying the Rarity of Skeletal Muscle Cancers

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Fine-mapping of genes determining extrafusal fiber properties in murine soleus muscle

Carroll, A. M., Cheng, R., Collie-Duguid, E. S. R., Meharg, C., Scholz, M. E., Fiering, S., Fields, J. L., Palmer, A. A., & Lionikas, A. (2017) · Physiological Genomics · doi:10.1152/physiolgenomics.00092.2016 · Cited by 10

The Effects of Mechanical Loading Variations on the Hypertrophic, Anti-Apoptotic, and Anti-Inflammatory Responses of Differentiated Cardiomyocyte-like H9C2 Cells

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miR-183/96/182 Cluster Regulates the Development of Bovine Myoblasts through Targeting FoxO1

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FoxO1: a novel insight into its molecular mechanisms in the regulation of skeletal muscle differentiation and fiber type specification

Xu, M., Chen, X., Chen, D., Yu, B., & Huang, Z. (2016) · Oncotarget · doi:10.18632/oncotarget.12891 · Cited by 122

FoxO1 regulates muscle fiber-type specification and inhibits calcineurin signaling during C2C12 myoblast differentiation

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Protein O-Fucosyltransferase 1 Expression Impacts Myogenic C2C12 Cell Commitment via the Notch Signaling Pathway

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Regulation of insulin-like growth factor–dependent myoblast differentiation by Foxo forkhead transcription factors

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Foxk1 promotes cell proliferation and represses myogenic differentiation by regulating Foxo4 and Mef2 factors

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