The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Helminth infections: the great neglected tropical diseases
Open accessAbstract
Helminths are parasitic worms. They are the most common infectious agents of humans in developing countries and produce a global burden of disease that exceeds better-known conditions, including malaria and tuberculosis. As we discuss here, new insights into fundamental helminth biology are accumulating through newly completed genome projects and the nascent application of transgenesis and RNA interference technologies. At the same time, our understanding of the dynamics of the transmission of helminths and the mechanisms of the Th2-type immune responses that are induced by infection with these parasitic worms has increased markedly. Ultimately, these advances in molecular and medical helminth biology should one day translate into a new and robust pipeline of drugs, diagnostics, and vaccines for targeting parasitic worms that infect humans.
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Cites
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Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm
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Self-citationAnthony, R. M., Urban, J. F., Alem, F., Hamed, H. A., Rozo, C. T., Boucher, J.-L., Van Rooijen, N., & Gause, W. C. (2006) · Nature Medicine · doi:10.1038/nm1451 · Cited by 522
Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis
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Cited by
Vos, T., Flaxman, A. D., Naghavi, M., Lozano, R., Michaud, C., Ezzati, M., Shibuya, K., Salomon, J. A., Abdalla, S., Aboyans, V., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61729-2 · Cited by 8,291
Self-citationBiological properties of extracellular vesicles and their physiological functions
Yáñez‐Mó, M., Siljander, P. R. ‐., Andreu, Z., Bedina Zavec, A., Borràs, F. E., Buzas, E. I., Buzas, K., Casal, E., Cappello, F., Carvalho, J., et al. (2015) · Journal of Extracellular Vesicles · doi:10.3402/jev.v4.27066 · Cited by 5,926
Hotez, P. J., Alvarado, M., Basáñez, M.-G., Bolliger, I., Bourne, R., Boussinesq, M., Brooker, S. J., Brown, A. S., Buckle, G., Budke, C. M., et al. (2014) · PLoS Neglected Tropical Diseases · doi:10.1371/journal.pntd.0002865 · Cited by 1,082
Self-citationIntestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites
Gerbe, F., Sidot, E., Smyth, D. J., Ohmoto, M., Matsumoto, I., Dardalhon, V., Cesses, P., Garnier, L., Pouzolles, M., Brulin, B., et al. (2016) · Nature · doi:10.1038/nature16527 · Cited by 961
Regulation of the host immune system by helminth parasites
Maizels, R. M., & McSorley, H. J. (2016) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2016.07.007 · Cited by 529
Metadata
- Authors
- Hotez, P. J., Brindley, P. J., Bethony, J. M., King, C. H., Pearce, E. J., & Jacobson, J.
- Venue
- Journal of Clinical Investigation
- Published
- 2008-04-01
- Volume
- 118
- Issue
- 4
- Pages
- 1311-1321
- ISSN
- 0021-9738 (ISSN-L)
- OpenAlex
- W2011671647
- Cited by
- 1,568
- References
- 7
- FWCI
- 43.33
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Hotez, P. J., Brindley, P. J., Bethony, J. M., King, C. H., Pearce, E. J., & Jacobson, J. (2008). Helminth infections: the great neglected tropical diseases. Journal of Clinical Investigation. https://doi.org/10.1172/jci34261
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
