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Cited by 1,082

The DOI matches its Crossref record; 72 of the 72 references it cites were found in a registry or an index.

The Global Burden of Disease Study 2010: Interpretation and Implications for the Neglected Tropical Diseases

Open access
Hotez, Peter J., Alvarado, Miriam, Basáñez, María-Gloria, Bolliger, Ian, Bourne, Rupert, Boussinesq, Michel, Brooker, Simon J., Brown, Ami Shah, Buckle, Geoffrey, Budke, Christine M., Carabin, Hélène, Coffeng, Luc E., Fèvre, Eric M., Fürst, Thomas, Halasa, Yara A., Jasrasaria, Rashmi, Johns, Nicole E., Keiser, Jennifer, King, Charles H., Lozano, Rafael, Murdoch, Michele E., O'Hanlon, Simon, Pion, Sébastien D. S., Pullan, Rachel L., Ramaiah, Kapa D., Roberts, Thomas, Shepard, Donald S., Smith, Jennifer L., Stolk, Wilma A., Undurraga, Eduardo A., Utzinger, Jürg, Wang, Mengru, Murray, Christopher J. L., Naghavi, Mohsen·2014·PLoS Neglected Tropical Diseases

Abstract

Cutaneous leishmaniasis is a neglected tropical disease, broadly distributed in the planet and with high incidence among socially vulnerable persons. It has been underestimated by healthcare systems and society, with a great burden of disease. Despite an available effective and well established treatment since the 50’s, it has been documented an increasing rate of resistance and treatment failure. Reports in Latin America, show resistance rates between 10-20% and 25% of subjects with treatment failure using first line drugs. Nevertheless, there is no clear association between reduced in vitro susceptibility from the parasite and treatment response. \n \nThis case control study with 34 subjects in a reference center in Bogotá, aimed to establish an association between reduced in vitro susceptibility and response to treatment. The results showed an OR 0.71 (IC 95% 0.085 – 9.39), which possibly means that there is no relation among the mentioned variables. \n \nThese results suggest that susceptibility testing would not impact clinical decision making as treatment failure predictors, therefore limiting its systematic use

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Metadata

Authors
Hotez, P. J., Alvarado, M., Basáñez, M.-G., Bolliger, I., Bourne, R., Boussinesq, M., Brooker, S. J., Brown, A. S., Buckle, G., Budke, C. M., Carabin, H., Coffeng, L. E., Fèvre, E. M., Fürst, T., Halasa, Y. A., Jasrasaria, R., Johns, N. E., Keiser, J., King, C. H., Lozano, R., Murdoch, M. E., O'Hanlon, S., Pion, S. D. S., Pullan, R. L., Ramaiah, K. D., Roberts, T., Shepard, D. S., Smith, J. L., Stolk, W. A., Undurraga, E. A., Utzinger, J., Wang, M., Murray, C. J. L., & Naghavi, M.
Venue
PLoS Neglected Tropical Diseases
Published
2014-07-24
Volume
8
Issue
7
Pages
e2865
ISSN
  • 1935-2727 (ISSN-L)
  • 1935-2735
OpenAlex
W2055623470
Cited by
1,082
References
72
FWCI
91.00
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: The Global Burden of Disease Study 2010: Interpretation and Implications for the Neglected Tropical Diseases. https://app.cochat.ai/papers/10.1371/journal.pntd.0002865
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Hotez, P. J., Alvarado, M., Basáñez, M.-G., Bolliger, I., Bourne, R., Boussinesq, M., Brooker, S. J., Brown, A. S., Buckle, G., Budke, C. M., Carabin, H., Coffeng, L. E., Fèvre, E. M., Fürst, T., Halasa, Y. A., Jasrasaria, R., Johns, N. E., Keiser, J., King, C. H., . . . Naghavi, M. (2014). The Global Burden of Disease Study 2010: Interpretation and Implications for the Neglected Tropical Diseases. PLoS Neglected Tropical Diseases. https://doi.org/10.1371/journal.pntd.0002865

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.