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Endocrine functions of bone in mineral metabolism regulation
Open accessAbstract
Given the dramatic increase in skeletal size during growth, the need to preserve skeletal mass during adulthood, and the large capacity of bone to store calcium and phosphate, juxtaposed with the essential role of phosphate in energy metabolism and the adverse effects of hyperphosphatemia, it is not surprising that a complex systems biology has evolved that permits cross-talk between bone and other organs to adjust phosphate balance and bone mineralization in response to changing physiological requirements. This review examines the newly discovered signaling pathways involved in the endocrine functions of bone, such as those mediated by the phosphaturic and 1,25(OH)2D-regulating hormone FGF23, and the broader systemic effects associated with abnormalities of calcium and phosphate homeostasis.
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“These cells are able to regulate phosphate metabolism by the production of FGF23, which acts on other organs including parathyroid gland and kidneys to reduce the circulating levels of phosphates [208, 209].”
From Biology of Bone Tissue: Structure, Function, and Factors That Influence Bone Cells (2015) · cites this paper as [208]
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Mutation of the mouse klotho gene leads to a syndrome resembling ageing
Kuro-o, M., Matsumura, Y., Aizawa, H., Kawaguchi, H., Suga, T., Utsugi, T., Ohyama, Y., Kurabayashi, M., Kaname, T., Kume, E., et al. (1997) · Nature · doi:10.1038/36285 · Cited by 3,837
Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis
Block, G. A., Klassen, P., Lazarus, J. M., Ofsthun, N. J., Lowrie, E. G., & Chertow, G. M. (2004) · Journal of the American Society of Nephrology · doi:10.1097/01.asn.0000133041.27682.a2 · Cited by 2,684
Suppression of Aging in Mice by the Hormone Klotho
Kurosu, H., Yamamoto, M., Clark, J. D., Pastor, J. V., Nandi, A., Gurnani, P., McGuinness, O. P., Chikuda, H., Yamaguchi, M., Kawaguchi, H., et al. (2005) · Science · doi:10.1126/science.1112766 · Cited by 1,935
Klotho converts canonical FGF receptor into a specific receptor for FGF23
Urakawa, I., Yamazaki, Y., Shimada, T., Iijima, K., Hasegawa, H., Okawa, K., Fujita, T., Fukumoto, S., & Yamashita, T. (2006) · Nature · doi:10.1038/nature05315 · Cited by 1,865
Fibroblast Growth Factor 23 and Mortality among Patients Undergoing Hemodialysis
Gutiérrez, O. M., Mannstadt, M., Isakova, T., Rauh‐Hain, J. A., Tamez, H. E., Shah, A., Smith, K. T., Lee, H., Thadhani, R., Jüppner, H., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0706130 · Cited by 1,729
Shimada, T., Kakitani, M., Yamazaki, Y., Hasegawa, H., Takeuchi, Y., Fujita, T., Fukumoto, S., Tomizuka, K., & Yamashita, T. (2004) · Journal of Clinical Investigation · doi:10.1172/jci19081 · Cited by 1,503
Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia
Shimada, T., Mizutani, S., Muto, T., Yoneya, T., Hino, R., Takeda, S., Takeuchi, Y., Fujita, T., Fukumoto, S., & Yamashita, T. (2001) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.101545198 · Cited by 1,391
Regulation of Fibroblast Growth Factor-23 Signaling by Klotho
Kurosu, H., Ogawa, Y., Miyoshi, M., Yamamoto, M., Nandi, A., Rosenblatt, K. P., Baum, M. G., Schiavi, S. C., Hu, M. C., Moe, O. W., et al. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.c500457200 · Cited by 1,381
Shimada, T., Kakitani, M., Yamazaki, Y., et al. (2004) · Journal of Clinical Investigation · doi:10.1172/jci200419081 · Cited by 1,368
Feng, J. Q., Ward, L. M., Liu, S., Lu, Y., Xie, Y., Yuan, B., Yu, X., Rauch, F., Davis, S. I., Zhang, S., et al. (2006) · Nature Genetics · doi:10.1038/ng1905 · Cited by 1,199
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Flagged first, then by citations
Research works printed but not linked: 4
- Ben-Dov, 2007, J. Clin. Invest., 117, 4003
- Yuan, 2008, J. Clin. Invest., 118, 722
- Xiao, 1998, Am. J. Physiol., 275, E700
- Fisher, 1994, Hum. Mol. Genet., 3, 2053
Cited by
Sorted by citations
Items 201–300 of 453
Saki, F., Kassaee, S. R., Salehifar, A., & Omrani, G. R. (2020) · BMC Nephrology · doi:10.1186/s12882-020-01826-5 · Cited by 25
Genetic causes of neonatal and infantile hypercalcaemia
Gorvin, C. M. (2021) · Pediatric Nephrology · doi:10.1007/s00467-021-05082-z · Cited by 25
Echocardiographic manifestations in end-stage renal disease
Ito, T., & Akamatsu, K. (2023) · Heart Failure Reviews · doi:10.1007/s10741-023-10376-5 · Cited by 25
Comparison of AMG 416 and cinacalcet in rodent models of uremia
Walter, S. A., Baruch, A., Alexander, S. T., Janes, J. R., Sho, E., Dong, J., Yin, Q., Maclean, D., Mendel, D. B., Karim, F. D., et al. (2014) · BMC Nephrology · doi:10.1186/1471-2369-15-81 · Cited by 25
Bone Development and Remodeling
Maes, C., & Kronenberg, H. M. (2015) · Elsevier eBooks · doi:10.1016/b978-0-323-18907-1.00060-3 · Cited by 26
Fibroblast Growth Factor 23 is Elevated in Tenofovir-Related Hypophosphatemia
Saeedi, R., Jiang, S. Y., Holmes, D. T., & Kendler, D. L. (2014) · Calcified Tissue International · doi:10.1007/s00223-014-9854-7 · Cited by 24
Park, Y. E., Musson, D. S., Naot, D., & Cornish, J. (2017) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2017.04.001 · Cited by 25
DiMeglio, L. A., & Imel, E. A. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-416015-6.00013-7 · Cited by 26
Speer, T., Groesdonk, H. V., Zapf, B., Buescher, V., Beyse, M., Duerr, L., Gewert, S., Krauss, P., Poppleton, A., Wagenpfeil, S., et al. (2015) · Critical Care · doi:10.1186/s13054-015-0925-6 · Cited by 24
Acıpınar, Ş., Hendek, M. K., Olgun, E., & Kısa, Ü. (2019) · Clinical Implant Dentistry and Related Research · doi:10.1111/cid.12832 · Cited by 23
Magnesium and Calcium Homeostasis Depend on KCTD1 Function in the Distal Nephron
Marneros, A. G. (2021) · Cell Reports · doi:10.1016/j.celrep.2020.108616 · Cited by 23
Wilkens, M. R., Mrochen, N., Breves, G., & Schröder, B. (2009) · Domestic Animal Endocrinology · doi:10.1016/j.domaniend.2009.10.003 · Cited by 23
Viaene, L., Meijers, B. K. I., Vanrenterghem, Y. F. C., & Evenepoel, P. (2012) · American Journal of Nephrology · doi:10.1159/000338299 · Cited by 23
Current concepts in perinatal mineral metabolism
Ohata, Y., Ozono, K., & Michigami, T. (2016) · Clinical Pediatric Endocrinology · doi:10.1297/cpe.25.9 · Cited by 23
Gombart, A. F. (2012) · CRC Press eBooks · doi:10.1201/b13714 · Cited by 23
Why Dialysis Patients Need Combination Therapy with Both Cholecalciferol and A Calcitriol Analogs
Jones, G. (2010) · Seminars in Dialysis · doi:10.1111/j.1525-139x.2010.00722.x · Cited by 22
Fibroblast growth factor 23, klotho and heparin
Thomas, S. M., Li, Q., & Faul, C. (2023) · Current Opinion in Nephrology & Hypertension · doi:10.1097/mnh.0000000000000895 · Cited by 22
Plasma FGF23 levels and heart rate variability in patients with stage 5 CKD
Zhang, L.-N., Yang, G., Cheng, C., Shen, C., Cui, Y.-Y., Zhang, J., Zhang, J., Shen, Z., Zeng, M., Ge, Y.-F., et al. (2014) · Osteoporosis International · doi:10.1007/s00198-014-2862-7 · Cited by 22
Vitamin D: what clinicians need to know
Wimalawansa, S. J. (2012) · Sri Lanka Journal of Diabetes Endocrinology and Metabolism · doi:10.4038/sjdem.v2i2.4776 · Cited by 24
Hiyamuta, H., Yamada, S., Taniguchi, M., Tokumoto, M., Tsuruya, K., Nakano, T., & Kitazono, T. (2020) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2020.11.020 · Cited by 22
Calcium and Phosphorus Homeostasis: Pathophysiology
Rigo, J., Pieltain, C., Viellevoye, R., & Bagnoli, F. (2012) · Springer eBooks · doi:10.1007/978-88-470-1405-3_49 · Cited by 21
Mizia‐Stec, K., Wieczorek, J., Polak, M., Wybraniec, M. T., Wozniak‐Skowerska, I., Hoffmann, A., Nowak, S., Wikarek, M., Wnuk-Wojnar, A. M., Chudek, J. T., et al. (2018) · Cytokine · doi:10.1016/j.cyto.2018.08.005 · Cited by 21
Rodrat, M., Wongdee, K., Panupinthu, N., Thongbunchoo, J., Teerapornpuntakit, J., Krishnamra, N., & Charoenphandhu, N. (2018) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2017.12.022 · Cited by 21
Correction: Altered Bone Development and an Increase in FGF-23 Expression in Enpp1−/−Mice
Mackenzie, N. C. W., Zhu, D., Milne, E., Hof, R. V., Martin, A., Quarles, L. D., Millán, J. L., Farquharson, C., & MacRae, V. E. (2012) · PLoS ONE · doi:10.1371/annotation/8f71d7e8-d81d-4878-bf14-79a313a7810b · Cited by 21
Self-citationHong, Y. A., Lim, J. H., Kim, M. Y., Kim, Y., Yang, K. S., Chung, B. H., Chung, S., Choi, B. S., Yang, C. W., Kim, Y., et al. (2014) · Clinical and Experimental Nephrology · doi:10.1007/s10157-014-0962-5 · Cited by 20
Fibroblast growth factor 23 mediates the phosphaturic actions of cadmium
Aranami, F., Segawa, H., Furutani, J., Kuwahara, S., Tominaga, R., Hanabusa, E., Tatsumi, S., Kido, S., Ito, M., & Miyamoto, K. (2010) · The Journal of Medical Investigation · doi:10.2152/jmi.57.95 · Cited by 20
Lee, M.-S., Chen, R. C.-Y., Chang, Y., Huang, Y.-C., & Wahlqvist, M. L. (2012) · The journal of nutrition health & aging · doi:10.1007/s12603-012-0379-3 · Cited by 20
Guo, R., Du, Y., Zhang, S., Liu, H., & Fu, Y. (2018) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2018.08.020 · Cited by 20
Severe, Symptomatic Hypocalcemia due to Denosumab Administration: Treatment and Clinical Course
Strickling, J. E., & Wilkowski, M. J. (2019) · Case Reports in Nephrology and Dialysis · doi:10.1159/000499824 · Cited by 20
Serum 25-hydroxyvitamin D measurement: Comparative evaluation of three automated immunoassays
Trimboli, F., Rotundo, S., Armili, S., Mimmi, S., Lucia, F., Montenegro, N., Antico, G. C., Cerra, A., Gaetano, M., Galato, F., et al. (2021) · Practical Laboratory Medicine · doi:10.1016/j.plabm.2021.e00251 · Cited by 20
Should biochemical markers of bone turnover be considered standard practice for safety pharmacology?
Henriksen, K., Bohren, K. M., Bay‐Jensen, A., & Karsdal, M. A. (2009) · Biomarkers · doi:10.3109/13547500903434519 · Cited by 20
Nitta, K., Itoyama, S., Ikejiri, K., Kinoshita, J., Nakanishi, K., Fukagawa, M., & Akizawa, T. (2023) · Kidney International Reports · doi:10.1016/j.ekir.2023.08.003 · Cited by 19
Intravenous Phosphate Loading Increases Fibroblast Growth Factor 23 in Uremic Rats
Arai-Nunota, N., Mizobuchi, M., Ogata, E., Yamazaki-Nakazawa, A., Kumata, C., Kondo, F., Hosaka, N., Koiwa, F., Kinugasa, E., Shibata, T., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0091096 · Cited by 19
Chacar, F. C., Kogika, M. M., Zafalon, R. V. A., & Brunetto, M. A. (2020) · Metabolites · doi:10.3390/metabo10120499 · Cited by 22
Nagata, Y., Imanishi, Y., Tateishi, T., Miyaoka, D., Kurajoh, M., Arnold, A., & Emoto, M. (2022) · Journal of the Endocrine Society · doi:10.1210/jendso/bvac027 · Cited by 19
Hematopoietic stem cell mobilization
Chang, H., Liou, Y.-S., & Sun, D. (2021) · Tzu Chi Medical Journal · doi:10.4103/tcmj.tcmj_98_21 · Cited by 18
Ross, A. C., Taylor, C. L., Yaktine, A. L., & Valle, H. B. D. (2011) · Cited by 18
Disorders of phosphorus homeostasis
Lee, R., & Weber, T. J. (2010) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0b013e32834041d4 · Cited by 18
Hormonal actions of vitamin D and its role beyond just being a vitamin: A review article
Khan, K., Akram, J., & Fazal, M. (2011) · Cited by 18
Hewison, M., & Adams, J. S. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-381978-9.10045-9 · Cited by 17
St‐Arnaud, R., & Demay, M. B. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-382040-2.10008-5 · Cited by 17
Yoshikawa, R., Yamamoto, H., Nakahashi, O., Kagawa, T., Tajiri, M., Nakao, M., Fukuda, S., Arai, H., Masuda, M., Iwano, M., et al. (2017) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.17-20 · Cited by 17
Calcium-sensing receptor signaling — How human disease informs biology
Gorvin, C. M. (2020) · Current Opinion in Endocrine and Metabolic Research · doi:10.1016/j.coemr.2020.06.007 · Cited by 17
Phosphate Metabolism in Cardiorenal Metabolic Disease
Gupta, D., Brietzke, S., Hayden, M. R., Kurukulasuriya, L. R., & Sowers, J. R. (2011) · Cardiorenal Medicine · doi:10.1159/000332388 · Cited by 17
Hu, W., He, J., Fu, W., Wang, C., Yue, H., Gu, J., Zhang, H., & Zhang, Z. (2018) · Journal of Clinical Densitometry · doi:10.1016/j.jocd.2018.08.005 · Cited by 17
Mutation analysis and serum FGF23 level in a patient with pulmonary alveolar microlithiasis
Olauson, H., Brandenburg, V. M., & Larsson, T. E. (2010) · Endocrine · doi:10.1007/s12020-009-9299-3 · Cited by 17
Holmlund-Suila, E. M., Viljakainen, H. T., Ljunggren, Ö., Hytinantti, T. K., Andersson, S., & Mäkitie, O. (2016) · Hormone Research in Paediatrics · doi:10.1159/000443988 · Cited by 16
Phosphatonins: physiological role and pathological changes.
Cavalli, L., Mazzotta, C., & Brandi, M. L. (2012) · Europe PMC (PubMed Central) · Cited by 16
Osteo-Renal Cross-Talk and Phosphate Metabolism by the FGF23-Klotho System
Ohnishi, M., & Razzaque, M. S. (2013) · Contributions to nephrology · doi:10.1159/000346774 · Cited by 15
Jones, G. (2012) · Rheumatic Disease Clinics of North America · doi:10.1016/j.rdc.2012.03.016 · Cited by 15
Fragkos, K. C., Sehgal, V., Rogers, J. P., Arulrajan, S., Pavanerathan, P., Barragry, J., Sebepos‐Rogers, G., Mehta, S. J., Caro, S. D., & Rahman, F. Z. (2020) · GastroHep · doi:10.1002/ygh2.415 · Cited by 15
Chronic Kidney Disease-Mineral Bone Disorder
Moe, S. M. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4377-0987-2.00008-x · Cited by 15
Molecular Control of Phosphorus Homeostasis and Precision Treatment of Hypophosphatemic Disorders
Weber, T. J., & Quarles, L. D. (2019) · Current Molecular Biology Reports · doi:10.1007/s40610-019-0118-1 · Cited by 15
Self-citationExtracellular vesicles in bone homeostasis: key roles of physiological and pathological conditions
Tamura, T., Yoshioka, Y., Sakamoto, S., Ichikawa, T., & Ochiya, T. (2022) · Journal of Bone and Mineral Metabolism · doi:10.1007/s00774-022-01362-2 · Cited by 15
What would we like to know, and what do we not know about fibroblast growth factor 23
Cozzolino, M. G., Galassi, A., Apetrii, M., & Covic, A. C. (2011) · Journal of Nephrology · doi:10.5301/jn.5000003 · Cited by 14
The osteocyte—A novel endocrine regulator of body phosphate homeostasis
Cheng, F., & Hulley, P. A. (2010) · Maturitas · doi:10.1016/j.maturitas.2010.08.011 · Cited by 14
New Insight into the Action of Vitamin D
Choi, H.-J. (2011) · Korean Journal of Family Medicine · doi:10.4082/kjfm.2011.32.2.89 · Cited by 14
Florenzano, P. F., Imel, E. A., Khan, A. A., Li, Z., Vincent, M., Nomura, T., Krolczyk, S., Johnson, B., & Ward, L. M. (2025) · Journal of Bone and Mineral Research · doi:10.1093/jbmr/zjaf063 · Cited by 13
Asamiya, Y., Yajima, A., Shimizu, S., Otsubo, S., Tsuchiya, K., & Nitta, K. (2014) · Osteoporosis International · doi:10.1007/s00198-014-2934-8 · Cited by 13
Liu, W., Zhou, Q., Ao, X., Yu, H., Peng, W., & He, N. (2012) · Journal of Cardiovascular Medicine · doi:10.2459/jcm.0b013e3283536859 · Cited by 13
Andronescu, E., Grumezescu, A. M., Guşă, M.-I., Holban, A. M., Ilie, F. C., Irimia, A., Nicoară, I.-F., & Ţone, M. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-42862-0.00006-7 · Cited by 13
Anderson, J. J. B., & Garner, S. C. (2011) · CRC Press eBooks · doi:10.1201/b11228-42 · Cited by 13
Synhaeve, N., Wade‐Gueye, N. M., Musilli, S., Frick, J., Grandcolas, L., Gruel, G., Souidi, M., Dublineau, I., & Bertho, J. (2012) · Journal of Applied Toxicology · doi:10.1002/jat.2834 · Cited by 12
In Vivo Deletion of CAR Resulted in High Bone Mass Phenotypes in Male Mice
Cho, H. Y., Jung, J., Park, H., Yang, J., Jung, S., An, J. H., Cho, S. W., Kim, S. W., Kim, S. Y., Kim, J. E., et al. (2013) · Journal of Cellular Physiology · doi:10.1002/jcp.24478 · Cited by 12
Transport of Calcium, Magnesium, and Phosphate
Bindels, R. J. M., Hoenderop, J. G. J., & Biber, J. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4160-6193-9.10007-7 · Cited by 12
The Effects of the Anti-aging Protein Klotho on Mucociliary Clearance
Garth, J. M., Easter, M., Harris, E. S., Sailland, J., Künzi, L., Chung, S., Dennis, J. S., Baumlin, N., Adewale, A. T., Rowe, S. M., et al. (2020) · Frontiers in Medicine · doi:10.3389/fmed.2019.00339 · Cited by 12
Dahir, K. M., Black, M., Gottesman, G. S., Imel, E. A., Mumm, S. R., Nichols, C., & Whyte, M. P. (2022) · JBMR Plus · doi:10.1002/jbm4.10692 · Cited by 12
Introduction to Ideal Characteristics and Advanced Biomedical Applications of Biomaterials
Kapusetti, G., More, N., & Choppadandi, M. (2019) · Springer eBooks · doi:10.1007/978-981-13-3705-5_8 · Cited by 13
Fibroblast growth factor 23 in hypophosphataemic HIV ‐positive adults on tenofovir
Bech, A. P., van Bentum, P., Nabbe, K. C., Gisolf, J., Richter, C., & de Boer, H. (2012) · HIV Medicine · doi:10.1111/j.1468-1293.2012.01015.x · Cited by 12
Vitamin D, Calcium, and Colorectal Neoplasia: New Insights on Mechanisms of Action
Jacobs, E. T., Jurutka, P. W., Martı́nez, M. E., & Alberts, D. S. (2009) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-09-0019 · Cited by 12
Chronic kidney disease is associated with increased risk of sudden cardiac death
Li, Y., Jiang, R., Ouyang, C., Wang, J., Yu, Q., Lü, J., Wei, H., Liu, S., Chen, Y., Cai, J., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-64254-9 · Cited by 11
Detlie, T. E., Lindstrøm, J. C., Jahnsen, M. E., Finnes, E., Zoller, H., Moum, B. A., & Jahnsen, J. (2021) · World Journal of Gastroenterology · doi:10.3748/wjg.v27.i17.2039 · Cited by 11
Cozzolino, M. G., Bruschetta, E., Cusi, D., Montanari, E., Giovenzana, M. E., & Galassi, A. (2012) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2012.730520 · Cited by 11
DiMeglio, L. A., & Imel, E. A. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813259-3.00013-0 · Cited by 12
The white adipose tissue connection with calcium and bone homeostasis
Bouillon, R., & Decallonne, B. (2010) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.175 · Cited by 11
Clinical application of calcium modeling in patients with chronic kidney disease
Bushinsky, D. A. (2011) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfr406 · Cited by 11
Hunt for the culprit of cardiovascular injury in kidney disease: Figure 1
Faul, C., & Wolf, M. S. (2015) · Cardiovascular Research · doi:10.1093/cvr/cvv228 · Cited by 11
Nakatani, S., Ishimura, E., Murase, T., Nakamura, T., Nakatani, A., Toi, N., Nishide, K., Uedono, H., Tsuda, A., Kurajoh, M., et al. (2021) · Kidney & Blood Pressure Research · doi:10.1159/000516610 · Cited by 10
Phosphate Homeostasis and Disorders of Phosphate Metabolism
Perumal, N. L., & Padidela, R. (2022) · Current Pediatric Reviews · doi:10.2174/1573396319666221221121350 · Cited by 10
The bone-heart axis in the pathogenesis of cardiovascular diseases: A narrative review
Vergatti, A., Abate, V., Iannuzzo, G., Barbato, A., FILIPPO, G. D., & Rendina, D. (2025) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2025.103872 · Cited by 11
Tertiary hyperparathyroidism in a patient with X-linked hypophosphatemic rickets.
Tournis, S., Γεωργούλας, Θ., Zafeiris, C., Papalexis, C., Petraki, K., & Lyritis, G. P. (2011) · PubMed · Cited by 10
Primary Hyperparathyroidism and the Kidney
Peacock, M. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-397166-1.00031-x · Cited by 10
Goljanek‐Whysall, K., Tridimas, A., McCormick, R., Russell, N.-J., Sloman, M., Sorani, A., Fraser, W. D., & Hannan, F. M. (2017) · Bone · doi:10.1016/j.bone.2017.10.002 · Cited by 10
Regulation of Renal and Extrarenal 1α-Hydroxylase
Larner, D. P., Adams, J. S., & Hewison, M. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809965-0.00008-2 · Cited by 10
Effect of Osteocyte-Ablation on Inorganic Phosphate Metabolism: Analysis of Bone–Kidney–Gut Axis
Fujii, O., Tatsumi, S., Ogata, M., Arakaki, T., Sakaguchi, H., Nomura, K., Miyagawa, A., Ikuta, K., Hanazaki, A., Kaneko, I., et al. (2017) · Frontiers in Endocrinology · doi:10.3389/fendo.2017.00359 · Cited by 10
Cai, D., Shao, J., & Xiao, Y. (2026) · Dental Research · doi:10.1016/j.dtrs.2026.100025 · Cited by 9
ASARM mineralization hypothesis: A bridge too far?
David, V., & Quarles, L. D. (2010) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.69 · Cited by 9
Self-citationThe effect of tibial dyschondroplasia on metabolic parameters in broiler chickens
İmik, H. (2012) · Ankara Üniversitesi Veteriner Fakültesi Dergisi · doi:10.1501/vetfak_0000002538 · Cited by 9
Favus, M. J. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4377-1604-7.00250-5 · Cited by 9
Vitamin D Regulation of Osteoblast Function
van de Peppel, J., Franceschi, R. T., Li, Y., & van der Eerden, B. C. J. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809965-0.00017-3 · Cited by 9
Utility of baseline serum phosphorus levels for predicting remission in acromegaly patients
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Metadata
- Authors
- Quarles, L. D.
- Affiliations
- University of Kansas Medical Center (US)
- Corresponding author
- Quarles, L. Darryl
- ORCID
- Quarles, L. Darryl
- Venue
- Journal of Clinical Investigation
- Published
- 2008-12-01
- Volume
- 118
- Issue
- 12
- Pages
- 3820-3828
- ISSN
- 0021-9738 (ISSN-L)
- PMC
- PMC2586800
- OpenAlex
- W2165433745
- Cited by
- 459
- References
- 117
- Citations by year
- 2026: 7 · 2025: 13 · 2024: 7 · 2023: 8 · 2022: 13 · 2021: 17 · 2020: 19 · 2019: 37 · 2018: 28 · 2017: 19 · 2016: 22 · 2015: 19 · 2014: 28 · 2013: 26 · 2012: 65
- FWCI
- 5.74
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Investigation (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR045955, R01-AR-45955, R56AR045955)
- Topics
- Health Sciences › Medicine › Nephrology › Parathyroid Disorders and Treatments
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Alkaline Phosphatase Research Studies
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Keywords
- bone endocrine function, mineral metabolism, calcium homeostasis, phosphate homeostasis, fibroblast growth factor 23, 1,25-dihydroxyvitamin D, bone mineralization, hyperphosphatemia, skeletal mass
- MeSH terms
- Fibroblast Growth Factor-23, Animals, Bone and Bones, Calcitriol, Calcium, Energy Metabolism, Fibroblast Growth Factors, Homeostasis, Humans, Phosphates, Bone Density, Hyperphosphatemia
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