Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E–deficient mice
Cyrus, Tillmann, Witztum, Joseph L., Rader, Daniel J., Tangirala, Rajendra, Fazio, Sergio, Linton, MacRae F., Funk, Colin D.·1999·Journal of Clinical Investigation
DOI 10.1172/jci5897
Cited by (528)
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- Genetics of coronary heart diseaseRossi P. Naoumova, Stuart A. Cook, Paul R. Cook, Timothy J. Aitman · 2007 · Cambridge University Press eBooks
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- Role of ShcA in atherosclerosis and chondrocyte differentiationAntoine Abou-Jaoude · 2018 · theses.fr (ABES)
- Structural Improvement of the Allosteric ALOX15 Inhibitor Octyl (N-(5-(1H-Indol-2-yl)-2-methoxyphenyl)sulfamoyl)carbamateViktor Gavrilyuk, Vladislav Aksenov, Kirill Petrov, Angelina V. Kurchatova, Dmitriy Bortnevskij, Alexander V. Zhuravlev, Alexey Golovanov, Hartmut Kühn, Igor Ivanov · 2026 · Molecules
- Role of 12/15-lipoxygenase and its metabolites in cardiovascular diseasesJiaqi Yu, Weicheng Ni, Yuanzhen Lin, Yanlin Gao, Jianghua Zhou, Yuyu Li · 2026 · Journal of Lipid Research
- BindingDB Entry 2581: Tryptamine and homotryptamine-based sulfonamides as potent and selective inhibitors of 15-lipoxygenase.BindingDB · 2008 · UC San Diego
- BindingDB Entry 6809: Synthesis and evaluation of a new series of 3,5-bis((5-bromo-6-methyl-2-t-aminopyrimidin-4-yl)thio)-4H-1,2,4-triazol-4-amines and their cyclized products 'pyrimidinylthio pyrimidotriazolothiadiazines' as 15- lipo-oxygenase inhibitors.BindingDB · 2015 · UC San Diego
- BindingDB Entry 8133: Synthesis and SAR comparative studies of 2-allyl-4-methoxy-1-alkoxybenzenes as 15-lipoxygenase inhibitors.BindingDB · 2017 · UC San Diego
- BindingDB Entry 50043845: Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase.BindingDB · 2014 · UC San Diego
- BindingDB Entry 50015253: -Substituted 5-(1BindingDB · 2023 · UC San Diego
- Oxidative Stress in Cardiovascular Disease: Potential Biomarkers and Their MeasurementsSubhendu Mukherjee, Dipak Kumar Das · 2011 · Humana Press eBooks