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FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma

Han, T., Wang, P., Wang, Y., Xun, W., Lei, J., Wang, T., Lü, Z., Gan, M., Zhang, W., Yu, B., et al. (2021) · Autophagy · doi:10.1080/15548627.2021.1987672 · Cited by 20

A distinct holoenzyme organization for two-subunit pyruvate carboxylase

Choi, P. H., Jo, J., Lin, Y.-C., Lin, M.-H., Chou, C., Dietrich, L. E. P., & Tong, L. (2016) · Nature Communications · doi:10.1038/ncomms12713 · Cited by 23

Long non-coding RNA MIR4435-1HG promotes cancer growth in clear cell renal cell carcinoma

Wu, K., Hu, L., Lv, X., Chen, J., Yan, Z., Jiang, J., Cheng, Y., & Hou, J. (2020) · Cancer Biomarkers · doi:10.3233/cbm-201451 · Cited by 20

Comprehensive isotopomer analysis of glutamate and aspartate in small tissue samples

Cai, F., Bezwada, D., Cai, L., Mahar, R., Wu, Z., Chang, M. C., Pachnis, P., Yang, C., Kelekar, S., Gu, W., et al. (2023) · Cell Metabolism · doi:10.1016/j.cmet.2023.07.013 · Cited by 17

Applications of chromatography-ultra high-resolution MS for stable isotope-resolved metabolomics (SIRM) reconstruction of metabolic networks

Sun, Q., Fan, T. W. ‐., Lane, A. N., & Higashi, R. M. (2019) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2019.115676 · Cited by 19

Loss of Rb1 Enhances Glycolytic Metabolism in Kras-Driven Lung Tumors In Vivo

Conroy, L. R., Dougherty, S. M., Kruer, T. L., Metcalf, S. A., Lorkiewicz, P. K., He, L., Yin, X., Zhang, X., Arumugam, S., Young, L. E. A., et al. (2020) · Cancers · doi:10.3390/cancers12010237 · Cited by 19

Aberrant Metabolism as Inductor of Epigenetic Changes in Breast Cancer: Therapeutic Opportunities

Coronel-Hernández, J., Pérez-Yépez, E. A., Delgado-Waldo, I., Contreras-Romero, C., Jacobo-Herrera, N. J., León, D. F. C.-D., & Pérez‐Plasencia, C. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.676562 · Cited by 19

In vivo analysis of lung cancer metabolism: nothing like the real thing

Hensley, C. T., & DeBerardinis, R. J. (2015) · Journal of Clinical Investigation · doi:10.1172/jci79188 · Cited by 19

Effects of Aging on Glucose and Lipid Metabolism in Mice

Lien, E. C., Vu, N., Westermark, A. M., Danai, L. V., Lau, A. N., Gültekin, Y., Kukurugya, M. A., Bennett, B. D., & Heiden, M. G. V. (2024) · Aging Cell · doi:10.1111/acel.14462 · Cited by 22

Integrated analysis of transcriptomic and metabolomic data demonstrates the significant role of pyruvate carboxylase in the progression of ovarian cancer

Shang, H., Zheng, J., & Tong, J. (2020) · Aging · doi:10.18632/aging.104004 · Cited by 18

The Natural History of T Cell Metabolism

Braun, M. Y. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22136779 · Cited by 18

Carbon sources and pathways for citrate secreted by human prostate cancer cells determined by NMR tracing and metabolic modeling

van Heijster, F. H. A., Breukels, V., Jansen, K. F. J., Schalken, J. A., & Heerschap, A. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2024357119 · Cited by 19

UCP2 Overexpression Redirects Glucose into Anabolic Metabolic Pathways

Sreedhar, A., Cassel, T., Smith, P., Lu, D., Nam, H. W., Lane, A. N., & Zhao, Y. (2018) · PROTEOMICS · doi:10.1002/pmic.201800353 · Cited by 20

AMPK activation protects astrocytes from hypoxia‑induced cell death

Barialai, L., Strecker, M. I., Luger, A., J�ger, M., Bruns, I., Sittig, A. C. M., Mildenberger, I. C., Heller, S., Delaidelli, A., Lorenz, N. I., et al. (2020) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2020.4528 · Cited by 17

Exhaled metabolic markers and relevant dysregulated pathways of lung cancer: a pilot study

Zou, Y., Hu, Y., Jiang, Z., Chen, Y., Zhou, Y., Wang, Z., Wang, Y., Jiang, G., Tan, Z., & Hu, F. (2022) · Annals of Medicine · doi:10.1080/07853890.2022.2048064 · Cited by 18

NMR-based urine metabolic profiling and immunohistochemistry analysis of nephron changes in a mouse model of hypoxia-induced acute kidney injury

Chihanga, T., Ruby, H. N., Ma, Q., Bashir, S., Devarajan, P., & Kennedy, M. A. (2018) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00500.2017 · Cited by 18

Regulating COX10-AS1 / miR-142-5p / PAICS axis inhibits the proliferation of non-small cell lung cancer

Tang, X., Wu, Y., Yang, J., & Zhu, W. (2021) · Bioengineered · doi:10.1080/21655979.2021.1957072 · Cited by 17

Prognostic Values of TIGAR Expression and 18F-FDG PET/CT in Clear Cell Renal Cell Carcinoma

Wang, X., Li, R., Chen, R., Huang, G., Zhou, X., & Liu, J. (2019) · Journal of Cancer · doi:10.7150/jca.33442 · Cited by 17

Abstract 1424: Enhanced pyruvate carboxylation is crucial to non-small cell lung cancer proliferation and anabolism

Sellers, K., Fox, M. P., Bousamra, M., Yan, J., Yuneva, M. O., Higashi, R. M., Lane, A. N., & Fan, T. W. ‐. (2014) · Cancer Research · doi:10.1158/1538-7445.am2014-1424

Abstract 1271: Human non small cell lung cancer tissue has enhanced expression of pyruvate carboxylase, but not glutaminase

Fox, M. P., Bousamra, M., Slone, S. P., Lane, A. N., & Fan, T. W. ‐. (2011) · Cancer Research · doi:10.1158/1538-7445.am2011-1271 · Cited by 1

Pyruvate carboxylase is upregulated in NSCLC to support proliferation and anabolism.

Sellers, K. (2013) · doi:10.18297/etd/1297

Pyruvate carboxylase is required for glutamine-independent growth of tumor cells

Cheng, T., Sudderth, J., Yang, C., Mullen, A. R., Jin, E. S., Matés, J. M., & DeBerardinis, R. J. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1016627108 · Cited by 475

Breast Cancer-Derived Lung Metastases Show Increased Pyruvate Carboxylase-Dependent Anaplerosis

Christen, S., Lorendeau, D., Schmieder, R., Broekaert, D., Metzger, K., Veys, K., Elia, I., Buescher, J. M., Orth, M. F., Davidson, S. M., et al. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.09.042 · Cited by 258