Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Chomczynski, P., & Sacchi, N. (1987) · Analytical Biochemistry · doi:10.1006/abio.1987.9999 · Cited by 65,240 · see citing works

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

Towbin, H., Staehelin, T., & Gordon, J. (1979) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.76.9.4350 · Cited by 51,421 · see citing works

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

Raza, H., John, A., & Nemmar, A. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350087 · Cited by 47,311 · see citing works

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

Chomczyński, P., & Sacchi, N. (1987) · Analytical Biochemistry · doi:10.1016/0003-2697(87)90021-2 · Cited by 47,092 · see citing works

Receptor Specificity of the Fibroblast Growth Factor Family

Ornitz, D. M., Xu, J., Colvin, J. S., McEwen, D. G., MacArthur, C. A., Coulier, F., Gao, G., & Goldfarb, M. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.25.15292 · Cited by 1,871 · see citing works

Relationships between surface, volume, and thickness of iliac trabecular bone in aging and in osteoporosis. Implications for the microanatomic and cellular mechanisms of bone loss.

PARFITT, A. M., Mathews, C. H. E., Villanueva, A. R., Kleerekoper, M., Frame, B., & Rao, D. S. (1983) · Journal of Clinical Investigation · doi:10.1172/jci111096 · Cited by 1,542 · see citing works

Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia.

Shiang, R., Thompson, L., Zhu, Y.-Z., Church, D., Fielder, T., Bocian, M., Winokur, S., & Wasmuth, J. (1994) · Cell · doi:10.1016/0092-8674(94)90302-6 · Cited by 1,291 · see citing works

Fgf10 is essential for limb and lung formation

Sekine, K., Ohuchi, H., Fujiwara, M., Yamasaki, M., Yoshizawa, T., Sato, T., Yagishita, N., Matsui, D., Koga, Y., Itoh, N., et al. (1999) · Nature Genetics · doi:10.1038/5096 · Cited by 1,283 · see citing works

Fibroblast growth factor receptor 3 is a negative regulator of bone growth.

Deng, C.-X., Wynshaw-Boris, A., Zhou, F., Kuo, A., & Leder, P. (1996) · Cell · doi:10.1016/s0092-8674(00)81069-7 · Cited by 1,095 · see citing works

Molecular Mechanisms Mediating Proliferation/Differentiation Interrelationships During Progressive Development of the Osteoblast Phenotype

Stein, G. S., & Lian, J. B. (1993) · Endocrine Reviews · doi:10.1210/edrv-14-4-424 · Cited by 1,058 · see citing works

Biological Roles of Fibroblast Growth Factor-2

Bikfalvi, A., Klein, S., Pintucci, G., & Rifkin, D. B. (1997) · Endocrine Reviews · doi:10.1210/edrv.18.1.0292 · Cited by 959 · see citing works

Heparin Affinity: Purification of a Tumor-Derived Capillary Endothelial Cell Growth Factor

Shing, Y., Folkman, J., Sullivan, R., Butterfield, C., Murray, J., & Klagsbrun, M. (1984) · Science · doi:10.1126/science.6199844 · Cited by 932 · see citing works

Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia

Rousseau, F., Bonaventure, J., Legeai-Mallet, L., Pelet, A., Rozet, J., Maroteaux, P., Merrer, M. L., & Munnich, A. (1994) · Nature · doi:10.1038/371252a0 · Cited by 920 · see citing works

A microtomographic system for the nondestructive evaluation of bone architecture

Ruegsegger, P., Koller, B. J., & Müller, R. (1996) · Calcified Tissue International · doi:10.1007/bf02509542 · Cited by 884 · see citing works

Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3

Colvin, J. S., Bohne, B. A., Harding, G. W., McEwen, D. G., & Ornitz, D. M. (1996) · Nature Genetics · doi:10.1038/ng0496-390 · Cited by 868 · see citing works

Growth factors in bone matrix. Isolation of multiple types by affinity chromatography on heparin-Sepharose.

Hauschka, P. V., Mavrakos, A. E., Iafrati, M. D., Doleman, S. E., & Klagsbrun, M. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)67143-1 · Cited by 857 · see citing works

The relationship between the structural and orthogonal compressive properties of trabecular bone

Goulet, R. W., Goldstein, S. A., Ciarelli, M. J., Kuhn, J. L., Brown, M. B., & Feldkamp, L. A. (1994) · Journal of Biomechanics · doi:10.1016/0021-9290(94)90014-0 · Cited by 741 · see citing works

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA.

Evers, R., Kool, M., van Deemter, L., Janssen, H., Calafat, J., Oomen, L. C. J. M., Paulusma, C. C., Elferink, R. P. J. O., Baas, F., Schinkel, A. H., et al. (1998) · Journal of Clinical Investigation · doi:10.1172/jci119886 · Cited by 623 · see citing works

Neuronal defects and delayed wound healing in mice lacking fibroblast growth factor 2.

Ortega, S., Ittmann, M., Tsang, S. H., Ehrlich, M., & Basilico, C. (1998) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.95.10.5672 · Cited by 622 · see citing works

Osteoblast and chondroblast differentiation

Aubin, J. E., Liu, F., Malaval, L., & Gupta, A. (1995) · Bone · doi:10.1016/8756-3282(95)00183-e · Cited by 596 · see citing works

Bone and Mineral Research/4

Premakumari, S. (1986) · The Indian Journal of Nutrition and Dietetics · Cited by 578 · see citing works

Release of basic fibroblast growth factor-heparan sulfate complexes from endothelial cells by plasminogen activator-mediated proteolytic activity.

Saksela, O., & Rifkin, D. B. (1990) · The Journal of cell biology · doi:10.1083/jcb.110.3.767 · Cited by 539 · see citing works

Distribution of basic fibroblast growth factor in the 18-day rat fetus: localization in the basement membranes of diverse tissues.

Gonzalez, A. M., Buscaglia, M., Ong, M., & Baird, A. (1990) · The Journal of Cell Biology · doi:10.1083/jcb.110.3.753 · Cited by 527 · see citing works

FGFR‐4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern.

Partanen, J., Mäkelä, T., Eerola, E., Korhonen, J., Hirvonen, H., Claesson-Welsh, L., & Alitalo, K. (1991) · EMBO Journal · doi:10.1002/j.1460-2075.1991.tb07654.x · Cited by 511 · see citing works

Fibroblast Growth Factor-2 Supports ex Vivo Expansion and Maintenance of Osteogenic Precursors from Human Bone Marrow

Martín, I., Muraglia, A., Campanile, G., Cancedda, R., & Quarto, R. (1997) · Endocrinology · doi:10.1210/endo.138.10.5425 · Cited by 471 · see citing works

Impaired cerebral cortex development and blood pressure regulation in FGF‐2‐deficient mice

Dono, R., Texidó, G., Dussel, R., Ehmke, H., & Zeller, R. (1998) · The EMBO Journal · doi:10.1093/emboj/17.15.4213 · Cited by 436 · see citing works

FGF-, BMP- and Shh-mediated signalling pathways in the regulation of cranial suture morphogenesis and calvarial bone development

Kim, H., Rice, D. P. C., Kettunen, P. J., & Thesleff, I. (1998) · Development · doi:10.1242/dev.125.7.1241 · Cited by 408 · see citing works

Fibroblast growth factor 2 control of vascular tone

Zhou, M., Sutliff, R., Paul, R. J., Lorenz, J. N., Hoying, J., Haudenschild, C., Yin, M., Coffin, J., Kong, L.-J., Kranias, E. G., et al. (1998) · Nature Medicine · doi:10.1038/nm0298-201 · Cited by 396 · see citing works

Developmental expression of two murine fibroblast growth factor receptors, fig and bek

Orr‐Urtreger, A., Givol, D., Yayon, A., Yarden, Y., & Lonai, P. (1991) · Development · doi:10.1242/dev.113.4.1419 · Cited by 393 · see citing works

Stimulatory Effects of Basic Fibroblast Growth Factor and Bone Morphogenetic Protein-2 on Osteogenic Differentiation of Rat Bone Marrow-Derived Mesenchymal Stem Cells

Hanada, K., Dennis, J. E., & Caplan, A. I. (1997) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1997.12.10.1606 · Cited by 380 · see citing works

Effects of basic fibroblast growth factor on bone formation in vitro.

CANALIS, E. M., & McCarthy, T. L. (1988) · Journal of Clinical Investigation · doi:10.1172/jci113490 · Cited by 372 · see citing works

Stimulation of fracture repair by recombinant human basic fibroblast growth factor in normal and streptozotocin-diabetic rats

Kawaguchi, H., Kurokawa, T., Hanada, K., Hiyama, Y., Tamura, M., Ogata, E., & Matsumoto, T. (1994) · Endocrinology · doi:10.1210/endo.135.2.8033826 · Cited by 339 · see citing works

Abnormal bone growth and selective translational regulation in basic fibroblast growth factor (FGF-2) transgenic mice.

Coffin, J. D., Florkiewicz, R. Z., Neumann, J. C., Mort-Hopkins, T., Dorn, G. W., Lightfoot, P. S., German, R. Z., Howles, P. N., Kier, A. B., & O’Toole, B. A. (1995) · Molecular Biology of the Cell · doi:10.1091/mbc.6.12.1861 · Cited by 301 · see citing works

Cultured Bovine Bone Cells Synthesize Basic Fibroblast Growth Factor and Store It in Their Extracellular Matrix

Globus, R. K., Plouët, J., & Gospodarowicz, D. (1989) · Endocrinology · doi:10.1210/endo-124-3-1539 · Cited by 296 · see citing works

A Chemically Defined Medium Supports in Vitro Proliferation and Maintains the Osteochondral Potential of Rat Marrow-Derived Mesenchymal Stem Cells

Lennon, D. P., Haynesworth, S. E., Young, R. G., Dennis, J. E., & Caplan, A. I. (1995) · Experimental Cell Research · doi:10.1006/excr.1995.1221 · Cited by 285 · see citing works

Regulation of Bovine Bone Cell Proliferation by Fibroblast Growth Factor and Transforming Growth Factorβ

Globus, R. K., Patterson‐Buckendahl, P., & Gospodarowicz, D. (1988) · Endocrinology · doi:10.1210/endo-123-1-98 · Cited by 266 · see citing works

Isolation of cDNAs encoding four mouse FGF family members and characterization of their expression patterns during embryogenesis

Hébert, J. M., Basilico, C., Goldfarb, M. P., Haub, O., & Martin, G. R. (1990) · Developmental Biology · doi:10.1016/0012-1606(90)90211-z · Cited by 257 · see citing works

Osteogenic stem cells in the bone marrow

Friedenstein, A. J. (1990) · Elsevier eBooks · doi:10.1016/b978-0-444-81371-8.50012-1 · Cited by 243 · see citing works

Increased Adipogenesis and Myelopoiesis in the Bone Marrow of SAMP6, a Murine Model of Defective Osteoblastogenesis and Low Turnover Osteopenia

Kajkenova, O., Lecka-Czernik, B., Gubrij, I., Hauser, S., Takahashi, K., Parfitt, A., Jilka, R., Manolagas, S. C., & Lipschitz, D. (1997) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1997.12.11.1772 · Cited by 239 · see citing works

Stimulation of endosteal bone formation by systemic injections of recombinant basic fibroblast growth factor in rats

Nakamura, T. (1995) · Endocrinology · doi:10.1210/en.136.3.1276 · Cited by 227 · see citing works

In VivoStimulation of Endosteal Bone Formation by Basic Fibroblast Growth Factor in Rats

Mayahara, H., Ito, T., Nagai, H., 宮嶌, 宏., Tsukuda, R., Taketomi, S., MIZOGUCHI, J., & Kato, K. (1993) · Growth Factors · doi:10.3109/08977199308991583 · Cited by 220 · see citing works

Basic fibroblast growth factor inhibits type I collagen gene expression in osteoblastic MC3T3-E1 cells.

Hurley, M. M., Abreu, C., Harrison, J. R., Lichtler, A., Raisz, L. G., & Kream, B. E. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)53361-5 · Cited by 219 · see citing works

Regulation of human bone marrow-derived osteoprogenitor cells by osteogenic growth factors.

Long, M. W., Robinson, J. A., Ashcraft, E., & Mann, K. G. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117738 · Cited by 218 · see citing works

Effect of basic fibroblast growth factor on the growth and differentiation of adult stromal bone marrow cells: Enhanced development of mineralized bone-like tissue in culture

Pitaru, S., Kotev‐Emeth, S., Noff, D., Kaffuler, S., & Savion, N. (1993) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650080804 · Cited by 212 · see citing works

Stimulation of endosteal bone formation by systemic injections of recombinant basic fibroblast growth factor in rats.

Nakamura, T., Hanada, K., Tamura, M., Shibanushi, T., Nigi, H., Tagawa, M., Fukumoto, S., & Matsumoto, T. (1995) · Endocrinology · doi:10.1210/endo.136.3.7867582 · Cited by 182 · see citing works

Fibroblast Growth Factor

Gospodarowicz, D. (1990) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-199008000-00038 · Cited by 172 · see citing works

Opposing Effects of Fibroblast Growth Factor and Pertussis Toxin on Alkaline Phosphatase, Osteopontin, Osteocalcin, and Type I Collagen mRNA Levels in ROS 17/2.8 Cells

Rodan, S. B., Wesolowski, G. A., Yoon, K. C., & Rodan, G. A. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)47201-3 · Cited by 167 · see citing works

Skeletal growth factor and other growth factors known to be present in bone matrix stimulate proliferation and protein synthesis in human bone cells

Wergedal, J. E., Mohan, S., Lundy, M. W., & Baylink, D. J. (1990) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650050212 · Cited by 164 · see citing works

Fibroblast growth factor receptors (FGFRs) and their roles in limb development

Xu, X., Weinstein, M. B., Li, C., & Deng, C. (1999) · Cell and Tissue Research · doi:10.1007/s004410051264 · Cited by 159 · see citing works

Effects of Fibroblast Growth Factors on Deoxyribonucleic Acid and Collagen Synthesis in Rat Parietal Bone Cells*

McCarthy, T. L., & CANALIS, E. M. (1989) · Endocrinology · doi:10.1210/endo-125-4-2118 · Cited by 151 · see citing works

Transcriptional induction of prostaglandin G/H synthase-2 by basic fibroblast growth factor.

Kawaguchi, H., Pilbeam, C. C., Gronowicz, G., Abreu, C., Fletcher, B. S., Herschman, H. R., Raisz, L. G., & Hurley, M. M. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118140 · Cited by 145 · see citing works

Phospholipase C release of basic fibroblast growth factor from human bone marrow cultures as a biologically active complex with a phosphatidylinositol-anchored heparan sulfate proteoglycan.

Brunner, G., Gabrilove, J. L., Rifkin, D. B., & Wilson, E. L. (1991) · The Journal of Cell Biology · doi:10.1083/jcb.114.6.1275 · Cited by 144 · see citing works

Effects of basic fibroblast growth factor (bFGF) on bone formation in growing rats

Nagai, H., Tsukuda, R., & Mayahara, H. (1995) · Bone · doi:10.1016/8756-3282(94)00049-2 · Cited by 141 · see citing works

Murine FGF-12 and FGF-13: expression in embryonic nervous system, connective tissue and heart

Hartung, H. D., Feldman, B., Lovec, H., Coulier, F., Birnbaum, D., & Goldfarb, M. P. (1997) · Mechanisms of Development · doi:10.1016/s0925-4773(97)00042-7 · Cited by 140 · see citing works

Basic Fibroblast Growth Factor Induces Osteoclast Formation in Murine Bone Marrow Cultures

Hurley, M. M., Lee, S. K., Raisz, L. G., Bernecker, P. M., & Lorenzo, J. A. (1998) · Bone · doi:10.1016/s8756-3282(97)00292-5 · Cited by 129 · see citing works

Expression and regulation of basic fibroblast growth factor mRNA levels in mouse osteoblastic MC3T3-E1 cells.

Hurley, M. M., Abreu, C., Gronowicz, G., Kawaguchi, H., & Lorenzo, J. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)37121-1 · Cited by 124 · see citing works

Systemic Administration of Acidic Fibroblast Growth Factor (FGF-1) Prevents Bone Loss and Increases New Bone Formation in Ovariectomized Rats

Dunstan, C. R., Boyce, R. W., Boyce, B. F., Garrett, I. R., Izbicka, E., Burgess, W. H., & Mundy, G. R. (1999) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1999.14.6.953 · Cited by 124 · see citing works

Genomic structure, mapping, activity and expression of fibroblast growth factor 17

Xu, J., Lawshé, A., MacArthur, C. A., & Ornitz, D. M. (1999) · Mechanisms of Development · doi:10.1016/s0925-4773(99)00034-9 · Cited by 117 · see citing works

Bone marrow cells are targets for the anabolic actions of prostaglandin E2 on bone: Induction of a transition from nonadherent to adherent osteoblast precursors

Scutt, A., & Bertram, P. (1995) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650100320 · Cited by 117 · see citing works

Bone Anabolic Effects of Basic Fibroblast Growth Factor in Ovariectomized Rats1

Liang, H., Pun, S., & Wronski, T. J. (1999) · Endocrinology · doi:10.1210/endo.140.12.7195 · Cited by 115 · see citing works

Parathyroid Hormone Regulates the Expression of Fibroblast Growth Factor-2 mRNA and Fibroblast Growth Factor Receptor mRNA in Osteoblastic Cells

Hurley, M. M., Tetradis, S., Huang, Y., Hock, J. M., Kream, B. E., Raisz, L. G., & Sabbieti, M. G. (1999) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1999.14.5.776 · Cited by 109 · see citing works

Basic Fibroblast Growth Factor in the Presence of Dexamethasone Stimulates Colony Formation, Expansion, and Osteoblastic Differentiation by Rat Bone Marrow Stromal Cells

Scutt, A. M., & Bertram, P. (1999) · Calcified Tissue International · doi:10.1007/s002239900581 · Cited by 105 · see citing works

Basic fibroblast growth factor enhances the growth and expression of the osteogenic phenotype of dexamethasone-treated human bone marrow-derived bone-like cells in culture

Pri‐Chen, S., Pitaru, S., Lokiec, F., & Savion, N. (1998) · Bone · doi:10.1016/s8756-3282(98)00087-8 · Cited by 101 · see citing works

Distribution of Fibroblast Growth Factor (FGF)-2 and FGF Receptor-1 Messenger RNA Expression and Protein Presence in the Mid-Trimester Human Fetus

Gonzalez, A. M., Hill, D. J., Logan, A., Maher, P. A., & Baird, A. (1996) · Pediatric Research · doi:10.1203/00006450-199603000-00001 · Cited by 99 · see citing works

Effects of tiludronate on bone mass, structure, and turnover at the epiphyseal, primary, and secondary spongiosa in the proximal tibia of growing rats after sciatic neurectomy

Murakami, H., Nakamura, T., Tsurukami, H., Abe, M., Barbier, A., & Suzuki, K. (1994) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650090906 · Cited by 99 · see citing works

Basic fibroblast growth factor enhances the capacity of bone marrow cells to form bone‐like nodules in vitro

Noff, D., Pitaru, S., & Savion, N. (1989) · FEBS Letters · doi:10.1016/0014-5793(89)80808-7 · Cited by 97 · see citing works

Transforming Growth Factor βs and Fibroblast Growth Factors and Their Receptors: Role in Sutural Biology and Craniosynostosis

Cohen, M. M. (1997) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1997.12.3.322 · Cited by 88 · see citing works

Antagonistic effects of FGF4 on BMP induction of apoptosis and chondrogenesis in the chick limb bud

Buckland, R. A., Collinson, J. M., Graham, E., Davidson, D. R., & Hill, R. E. (1998) · Mechanisms of Development · doi:10.1016/s0925-4773(98)00008-2 · Cited by 86 · see citing works

Effects of interleukin 3 and of granulocyte‐macrophage and macrophage colony stimulating factors on osteoclast differentiation from mouse hemopoietic tissue

Hattersley, G., & Chambers, T. J. (1990) · Journal of Cellular Physiology · doi:10.1002/jcp.1041420125 · Cited by 83 · see citing works

Long-Term Culture of Human Bone Marrow Stromal Cells in the Presence of Basic Fibroblast Growth Factor

Oliver, L., Rifkin, D. B., Gabrilove, J. L., Hannocks, M., & Wilson, E. L. (1990) · Growth Factors · doi:10.3109/08977199009043907 · Cited by 80 · see citing works

In vitro effects of growth factors and dexamethasone on rat marrow stromal cells.

Locklin, R. M., Williamson, M. C., Beresford, J. N., Triffitt, J. T., & Owen, M. E. (1995) · PubMed · Cited by 74 · see citing works

Prostaglandins Regulate the Expression of Fibroblast Growth Factor-2 in Bone

Sabbieti, M. G., Marchetti, L., Abreu, C., Montero, A., Hand, A. R., Raisz, L. G., & Hurley, M. M. (1999) · Endocrinology · doi:10.1210/endo.140.1.6442 · Cited by 65 · see citing works

Basic fibroblast growth factor and hematopoiesis.

Allouche, M. (1995) · PubMed · Cited by 62 · see citing works

The interaction of heparin and basic fibroblast growth factor on collagen synthesis in 21-day fetal rat calvariae

Hurley, M. M., Kessler, M., Gronowicz, G., & Raisz, L. G. (1992) · Endocrinology · doi:10.1210/endo.130.5.1374012 · Cited by 57 · see citing works

Preliminary characterization of porcine bone marrow stromal cells: Skeletogenic potential, colony-forming activity, and response to dexamethasone, transforming growth factor β, and basic fibroblast growth factor

Thomson, B. M., Bennett, J. H., Dean, V., Triffitt, J. T., Meikle, M. C., & Loveridge, N. (1993) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650081004 · Cited by 57 · see citing works

Intracrine and Autocrine Effects of Basic Fibroblast Growth Factor in Vascular Smooth Muscle Cells

Davis, M. G., Zhou, M., Ali, S., Coffin, J. D., Doetschman, T., & Dorn, G. W. (1997) · Journal of Molecular and Cellular Cardiology · doi:10.1006/jmcc.1997.0383 · Cited by 50 · see citing works

Stimulation of bone formation by intraosseous injection of basic fibroblast growth factor in ovariectomised rats

Nakamura, K., Kurokawa, T., Aoyama, I., Hanada, K., Tamura, M., & Kawaguchi, H. (1998) · International Orthopaedics · doi:10.1007/s002640050207 · Cited by 50 · see citing works

Basic fibroblast growth factor (BFGF) immunoreactivity as a possible link between head injury and impaired bone fracture healing

Wildburger, R., Žarković, N., Egger, G., Petek, W., Žarković, K., & Hofer, H. P. (1994) · Bone and Mineral · doi:10.1016/s0169-6009(08)80192-4 · Cited by 47 · see citing works

The effects of recombinant human insulin-like growth factor (rhIGF)-1 and rhIGF-1/IGF binding protein-3 administration on rat osteopenia induced by ovariectomy with concomitant bilateral sciatic neurectomy

Narusawa, K., Nakamura, T., Suzuki, K., Matsuoka, Y., Lee, L., Tanaka, H., & Seino, Y. (1995) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650101204 · Cited by 47 · see citing works

Signal transduction by basic fibroblast growth factor in rat osteoblastic py1a cells

Hurley, M. M., Marcello, K., Abreu, C., & Kessler, M. (1996) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650110910 · Cited by 46 · see citing works

Transcriptional activation of c-fos and c-jun protooncogenes by serum growth factors in osteoblast-like MC3T3-E1 cells

Okazaki, R., Ikeda, K., Sakamoto, A., Nakano, T., Morimoto, K., Kikuchi, T., Urakawa, K., Ogata, E., & Matsumoto, T. (1992) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650071006 · Cited by 42 · see citing works

The use of polymerase chain reaction generated nucleotide sequences as probes for hybridization

Scully, S. P., Joyce, M. E., Abidi, N., & Bolander, M. E. (1990) · Molecular and Cellular Probes · doi:10.1016/0890-8508(90)90007-m · Cited by 40 · see citing works

The effect of recombinant human basic fibroblast growth factor rhfgf-2 on human osteoblast in growth and phenotype expression

Berrada, S., Lefebvre, F., & Harmand, M. (1995) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/bf02634091 · Cited by 24 · see citing works

Transcriptional Regulation of the Collagenase Gene by Basic Fibroblast Growth Factor in Osteoblastic MC3T3-E1 Cells

Hurley, M. M., Marcello, K., Abreu, C., Brinckerhoff, C., Bowik, C., & Hibbs, M. S. (1995) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1995.2292 · Cited by 23 · see citing works

Biology of Bone Tissue: Structure, Function, and Factors That Influence Bone Cells

Florencio-Silva, R., Sasso, G. R. D. S., Sasso-Cerri, E., Simões, M. J., & Cerri, P. S. (2015) · BioMed Research International · doi:10.1155/2015/421746 · Cited by 2,044 · see citing works

The Fibroblast Growth Factor signaling pathway

Ornitz, D. M., & Itoh, N. (2015) · WIREs Developmental Biology · doi:10.1002/wdev.176 · Cited by 2,050 · see citing works

Mechanisms of bone development and repair

Salhotra, A., Shah, H. N., Lévi, B., & Longaker, M. T. (2020) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-020-00279-w · Cited by 1,243 · see citing works

Building strong bones: molecular regulation of the osteoblast lineage

Long, F. (2011) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3254 · Cited by 1,149 · see citing works

The Osteoblast: A Sophisticated Fibroblast under Central Surveillance

Ducy, P. F., Schinke, T., & Karsenty, G. (2000) · Science · doi:10.1126/science.289.5484.1501 · Cited by 1,121 · see citing works

Osteogenesis and angiogenesis: The potential for engineering bone

Kanczler, J. M., & Oreffo, R. (2008) · European Cells and Materials · doi:10.22203/ecm.v015a08 · Cited by 984 · see citing works

Pathogenesis of bone fragility in women and men

Seeman, E. (2002) · The Lancet · doi:10.1016/s0140-6736(02)08706-8 · Cited by 909 · see citing works

FGF signaling pathways in endochondral and intramembranous bone development and human genetic diseasePreprint

Ornitz, D. M., & Marie, P. J. (2002) · Genes & Development · doi:10.1101/gad.990702 · Cited by 902 · see citing works

Signaling and transcriptional regulation in osteoblast commitment and differentiation

Huang, W. (2007) · Frontiers in bioscience · doi:10.2741/2296 · Cited by 649 · see citing works

Retention of Multilineage Differentiation Potential of Mesenchymal Cells during Proliferation in Response to FGF

Tsutsumi, S., Shimazu, A., Miyazaki, K., Pan, H., Koike, C., Yoshida, E., Takagishi, K., & Kato, Y. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.5777 · Cited by 574 · see citing works

v-ATPase V0 subunit d2–deficient mice exhibit impaired osteoclast fusion and increased bone formation

Lee, S.-H., Rho, J., Jeong, D., Sul, J., Kim, T. S., Kim, N., Kang, J.-S., Miyamoto, T. K., Suda, T., Lee, S., et al. (2006) · Nature Medicine · doi:10.1038/nm1514 · Cited by 547 · see citing works

Regulation of the osteoblast‐specific transcription factor, Runx2: Responsiveness to multiple signal transduction pathways

Franceschi, R. T., & Xiao, G. (2003) · Journal of Cellular Biochemistry · doi:10.1002/jcb.10369 · Cited by 540 · see citing works

Physiological Bone Remodeling: Systemic Regulation and Growth Factor Involvement

Siddiqui, J. A., & Partridge, N. C. (2016) · Physiology · doi:10.1152/physiol.00061.2014 · Cited by 546 · see citing works

Integration of BMP, Wnt, and notch signaling pathways in osteoblast differentiation

Lin, G. L., & Hankenson, K. D. (2011) · Journal of Cellular Biochemistry · doi:10.1002/jcb.23287 · Cited by 508 · see citing works

Functions and regulations of fibroblast growth factor signaling during embryonic development.

Thisse, B., & Thisse, C. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.09.011 · Cited by 554 · see citing works

FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis.Preprint

Ohbayashi, N., Shibayama, M., Kurotaki, Y., Imanishi, M., Fujimori, T., Itoh, N., & Takada, S. (2002) · Genes & Development · doi:10.1101/gad.965702 · Cited by 487 · see citing works

Bringing new life to damaged bone: The importance of angiogenesis in bone repair and regeneration

Stegen, S., van Gastel, N., & Carmeliet, G. (2014) · Bone · doi:10.1016/j.bone.2014.09.017 · Cited by 479 · see citing works

Blood vessel formation and function in bone

Sivaraj, K. K., & Adams, R. H. (2016) · Development · doi:10.1242/dev.136861 · Cited by 439 · see citing works

Fibroblast growth factor signaling in skeletal development and diseasePreprint

Ornitz, D. M., & Marie, P. J. (2015) · Genes & Development · doi:10.1101/gad.266551.115 · Cited by 419 · see citing works

Osteoblast and osteocyte: Games without frontiers

Capulli, M., Paone, R., & Rucci, N. (2014) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2014.05.003 · Cited by 413 · see citing works

Bone regeneration and stem cells

Arvidson, K., Abdallah, B. M., Applegate, L. A., Baldini, N., Cenni, E., Gómez‐Barrena, E., Granchi, D., Kassem, M. S., Konttinen, Y. T., Mustafa, K. B. E., et al. (2010) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2010.01224.x · Cited by 407 · see citing works

Fibroblast Growth Factor 2 Induction of the Osteocalcin Gene Requires MAPK Activity and Phosphorylation of the Osteoblast Transcription Factor, Cbfa1/Runx2

Xiao, G., Jiang, D., Gopalakrishnan, R., & Franceschi, R. T. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m206057200 · Cited by 379 · see citing works

Comparison of human dental pulp and bone marrow stromal stem cells by cDNA microarray analysis

Shi, S., Robey, P. G., & Gronthos, S. (2001) · Bone · doi:10.1016/s8756-3282(01)00612-3 · Cited by 378 · see citing works

FGF signaling in the developing endochondral skeleton

Ornitz, D. M. (2005) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2005.02.003 · Cited by 355 · see citing works

Regulation of Osteoblast Differentiation by Cytokine Networks

Amarasekara, D. S., Kim, S., & Rho, J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22062851 · Cited by 350 · see citing works

Micro-CT in small animal and specimen imaging

Holdsworth, D. W., & Thornton, M. M. (2002) · Trends in biotechnology · doi:10.1016/s0167-7799(02)02004-8 · Cited by 336 · see citing works

Runx2: A master organizer of gene transcription in developing and maturing osteoblasts

Schroeder, T. M., Jensen, E. D., & Westendorf, J. J. (2005) · Birth Defects Research Part C Embryo Today Reviews · doi:10.1002/bdrc.20043 · Cited by 333 · see citing works

Signaling networks in RUNX2‐dependent bone development

Komori, T. (2011) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22994 · Cited by 329 · see citing works

Articular cartilage and osteochondral tissue engineering techniques: Recent advances and challenges

Wei, W., & Dai, H. (2021) · Bioactive Materials · doi:10.1016/j.bioactmat.2021.05.011 · Cited by 328 · see citing works

Role of FGF/FGFR signaling in skeletal development and homeostasis: learning from mouse models

Su, N. Y., Jin, M. Y., & Chen, L. (2014) · Bone Research · doi:10.1038/boneres.2014.3 · Cited by 291 · see citing works

Fibroblast growth factor signaling controlling osteoblast differentiation

Marie, P. J. (2003) · Gene · doi:10.1016/s0378-1119(03)00748-0 · Cited by 274 · see citing works

Angiogenic factors in bone local environment

Chim, S. M., Tickner, J. C., Chow, S. T., Kuek, V., Guo, B., Zhang, G., Rosen, V., Erber, W. N., & Xu, J. (2013) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2013.03.008 · Cited by 265 · see citing works

Achondroplasia: Development, pathogenesis, and therapy

Ornitz, D. M., & Legeai‐Mallet, L. (2016) · Developmental Dynamics · doi:10.1002/dvdy.24479 · Cited by 264 · see citing works

Autocrine Fibroblast Growth Factor 2 Signaling Is Critical for Self‐Renewal of Human Multipotent Adipose‐Derived Stem Cells

Zaragosi, L., Ailhaud, G. P., & Dani, C. (2006) · Stem Cells · doi:10.1634/stemcells.2006-0006 · Cited by 252 · see citing works

The Protein Kinase C Pathway Plays a Central Role in the Fibroblast Growth Factor-stimulated Expression and Transactivation Activity of Runx2

Kim, H., Kim, J. H., Bae, S., Choi, J., Kim, H., & Ryoo, H. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m203750200 · Cited by 235 · see citing works

Mechanisms of aortic valve calcification

Mohler, E. R. (2004) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2004.08.013 · Cited by 228 · see citing works

Invited Review: Pathogenesis of osteoporosis

Seeman, E. (2003) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00564.2003 · Cited by 226 · see citing works

Exosomes: novel effectors of human platelet lysate activity

Torreggiani, E., Perut, F., Roncuzzi, L., Zini, N., Baglio, S. R., & Baldini, N. (2014) · European Cells and Materials · doi:10.22203/ecm.v028a11 · Cited by 215 · see citing works

Skeletal Growth Factors

CANALIS, E. M. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-375098-3.50020-2 · Cited by 208 · see citing works

Fibroblast growth factor-18 is a trophic factor for mature chondrocytes and their progenitors

Ellsworth, J. L., Berry, J., Bukowski, T. R., Claus, J., Feldhaus, A. L., Holderman, S. D., Holdren, M. S., Lum, K. D., Moore, E. E., Raymond, F., et al. (2002) · Osteoarthritis and Cartilage · doi:10.1053/joca.2002.0514 · Cited by 206 · see citing works

Myostatin (GDF-8) as a key factor linking muscle mass and bone structure.

Elkasrawy, M., & Hamrick, M. W. (2010) · PubMed · Cited by 203 · see citing works

Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation.

Jacob, A. L., Smith, C. S., Partanen, J., & Ornitz, D. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.05.031 · Cited by 212 · see citing works

Signaling Networks that Control the Lineage Commitment and Differentiation of Bone Cells

Soltanoff, C. S., Yang, S., Chen, W., & Li, Y. (2009) · Critical Reviews in Eukaryotic Gene Expression · doi:10.1615/critreveukargeneexpr.v19.i1.10 · Cited by 196 · see citing works

A review of the latest insights into the mechanism of action of strontium in bone

Marx, D., Yazdi, A. R., Papini, M., & Towler, M. R. (2020) · Bone Reports · doi:10.1016/j.bonr.2020.100273 · Cited by 196 · see citing works

Glycoprotein 130 regulates bone turnover and bone size by distinct downstream signaling pathways

Sims, N. A., Jenkins, B. J., Quinn, J. M. W., Nakamura, A., Glatt, M., Gillespie, M. T., Ernst, M., & Martin, T. J. (2004) · Journal of Clinical Investigation · doi:10.1172/jci19872 · Cited by 192 · see citing works

The Interplay between the Bone and the Immune System

Mori, G., D’Amelio, P., Faccio, R., & Brunetti, G. (2013) · Clinical and Developmental Immunology · doi:10.1155/2013/720504 · Cited by 193 · see citing works

Role of FGFs/FGFRs in skeletal development and bone regeneration

Du, X.-L., Xie, Y.-L., Xian, C. J., & Chen, L. (2012) · Journal of Cellular Physiology · doi:10.1002/jcp.24083 · Cited by 156 · see citing works

Rapamycin inhibits osteoblast proliferation and differentiation in MC3T3‐E1 cells and primary mouse bone marrow stromal cells

Singha, U. K., Jiang, Y., Yu, S., Luo, M., Lu, Y., Zhang, J., & Xiao, G. (2007) · Journal of Cellular Biochemistry · doi:10.1002/jcb.21411 · Cited by 180 · see citing works

Effects of FGF-2/-9 in calvarial bone cell cultures: differentiation stage-dependent mitogenic effect, inverse regulation of BMP-2 and noggin, and enhancement of osteogenic potential

Fakhry, A., Ratisoontorn, C., Vedhachalam, C., Salhab, I., Koyama, E., Leboy, P., Pacifici, M., Kirschner, R. E., & Nah, H. (2005) · Bone · doi:10.1016/j.bone.2004.10.003 · Cited by 179 · see citing works

Bone Vasculature and Bone Marrow Vascular Niches in Health and Disease

Chen, J., Hendriks, M., Chatzis, A., Ramasamy, S. K., & Kusumbe, A. P. (2020) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.4171 · Cited by 175 · see citing works

Regulation of Osteoblast, Chondrocyte, and Osteoclast Functions by Fibroblast Growth Factor (FGF)-18 in Comparison with FGF-2 and FGF-10

Shimoaka, T., Ogasawara, T., Yonamine, A., Chikazu, D., Kawano, H., Nakamura, K., Itoh, N., & Kawaguchi, H. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m108653200 · Cited by 168 · see citing works

Interleukin‐11 Receptor Signaling Is Required for Normal Bone Remodeling

Sims, N. A., Jenkins, B., Nakamura, A., Quinn, J. M., Li, R.-L., Gillespie, M. T., Ernst, M., Robb, L., & Martin, T. J. (2005) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.050209 · Cited by 171 · see citing works

Fibroblast Growth Factor Receptor 2 Promotes Osteogenic Differentiation in Mesenchymal Cells via ERK1/2 and Protein Kinase C Signaling

Miraoui, H., Oudina, K., Petite, H., Tanimoto, Y., Moriyama, K., & Marie, P. J. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m805432200 · Cited by 164 · see citing works

Human Parathyroid Hormone 1–34 Reverses Bone Loss in Ovariectomized Mice

Alexander, J. M., Bab, I., Fish, S., Müller, R., Uchiyama, T., Gronowicz, G., Nahounou, M., Zhao, Q., White, D. W., Chorev, M., et al. (2001) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2001.16.9.1665 · Cited by 156 · see citing works

FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod.

Hung, I. H., Yu, K., Lavine, K. J., & Ornitz, D. (2007) · Developmental Biology · doi:10.1016/j.ydbio.2007.04.048 · Cited by 160 · see citing works

Biology of Bone: The Vasculature of the Skeletal SystemPreprint

Watson, E. L., & Adams, R. H. (2017) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a031559 · Cited by 153 · see citing works

Fgf-9 is required for angiogenesis and osteogenesis in long bone repair

Behr, B., Leucht, P., Longaker, M. T., & Quarto, N. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1003317107 · Cited by 145 · see citing works

Fibroblast Growth Factor Receptor Signaling Crosstalk in Skeletogenesis

Miraoui, H., & Marie, P. (2010) · Science Signaling · doi:10.1126/scisignal.3146re9 · Cited by 106 · see citing works

Defective bone mineralization and osteopenia in young adult FGFR3-/- mice.

Valverde-Franco, G., Liu, H., Davidson, D., Chai, S., Valderrama-Carvajal, H., Goltzman, D., Ornitz, D., & Henderson, J. (2003) · Human Molecular Genetics · doi:10.1093/hmg/ddh034 · Cited by 143 · see citing works

HGF inhibits BMP-induced osteoblastogenesis: possible implications for the bone disease of multiple myeloma

Standal, T., Abildgaard, N., Fagerli, U.-M., Stordal, B., Hjertner, Ø., Borset, M., & Sundan, A. (2007) · Blood · doi:10.1182/blood-2006-07-034884 · Cited by 167 · see citing works

Fibroblast growth factor expression in the postnatal growth plate

Lazarus, J. E., Hegde, A. A., de Andrade, A. C., Nilsson, O., & Baron, J. (2006) · Bone · doi:10.1016/j.bone.2006.10.013 · Cited by 133 · see citing works

Embryonic Submandibular Gland Morphogenesis: Stage-Specific Protein Localization of FGFs, BMPs, Pax6 and Pax9 in Normal Mice and Abnormal SMG Phenotypes in FgfR2-IIIc+/Δ, BMP7–/– and Pax6–/–Mice

Jaskoll, T. F., Zhou, Y. M., Chai, Y., Makarenkova, H. P., Collinson, J. M., West, J. D., Hajihosseini, M. K., Lee, J., & Melnick, M. (2001) · Cells Tissues Organs · doi:10.1159/000046183 · Cited by 132 · see citing works

Disruption of the Fgf2 gene activates the adipogenic and suppresses the osteogenic program in mesenchymal marrow stromal stem cells

Xiao, L., Sobue, T., Esliger, A., Kronenberg, M. S., Coffin, J. D., Doetschman, T., & Hurley, M. M. (2010) · Bone · doi:10.1016/j.bone.2010.05.021 · Cited by 127 · see citing works

FGF2-activated ERK Mitogen-activated Protein Kinase Enhances Runx2 Acetylation and Stabilization

Park, O.-J., Kim, H., Woo, K. M., Baek, J., & Ryoo, H. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.055053 · Cited by 127 · see citing works

The Regulatory Role of Signaling Crosstalk in Hypertrophy of MSCs and Human Articular Chondrocytes

Zhong, L., Huang, X., Karperien, M., & Post, J. N. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms160819225 · Cited by 125 · see citing works

FGF-2 expands murine hematopoietic stem and progenitor cells via proliferation of stromal cells, c-Kit activation, and CXCL12 down-regulation

Itkin, T., Ludin, A., Gradus, B., Gur‐Cohen, S., Kalinkovich, A., Schajnovitz, A., Ovadya, Y., Kollet, Ó., Canaani, J., Shezen, E., et al. (2012) · Blood · doi:10.1182/blood-2011-11-394692 · Cited by 120 · see citing works

Fibroblast Growth Factor 2 Stimulation of Osteoblast Differentiation and Bone Formation Is Mediated by Modulation of the Wnt Signaling Pathway

Fei, Y., Xiao, L., Doetschman, T., Coffin, D. J., & Hurley, M. M. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.274910 · Cited by 120 · see citing works

FGF9 monomer/dimer equilibrium regulates extracellular matrix affinity and tissue diffusion

Harada, M., Murakami, H., Okawa, A., Okimoto, N., Hiraoka, S., Nakahara, T., Akasaka, R., Shiraishi, Y., Futatsugi, N., Mizutani-Koseki, Y., et al. (2009) · Nature Genetics · doi:10.1038/ng.316 · Cited by 124 · see citing works

Genotype–phenotype analysis of 4q deletion syndrome: Proposal of a critical region

Strehle, E., Yu, L., Rosenfeld, J. A., Donkervoort, S. C., Zhou, Y., Chen, T., Martinez, J. E., Fan, Y., Barbouth, D., Zhu, H., et al. (2012) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.35502 · Cited by 114 · see citing works

Osteogenesis of Adipose-Derived Stem Cells

Grottkau, B. E., & Lin, Y. (2013) · Bone Research · doi:10.4248/br201302003 · Cited by 117 · see citing works

Delivery systems for bone growth factors — the new players in skeletal regeneration

Rose, F. R. A. J., Hou, Q., & Oreffo, R. O. C. (2004) · Journal of Pharmacy and Pharmacology · doi:10.1211/0022357023312 · Cited by 115 · see citing works

Comparison of Explant-Derived and Enzymatic Digestion-Derived MSCs and the Growth Factors from Wharton’s Jelly

Yoon, J. H., Roh, E. Y., Shin, S., Jung, N. H., Song, E. Y., Chang, J. Y., Kim, B. J., & Jeon, H. W. (2013) · BioMed Research International · doi:10.1155/2013/428726 · Cited by 113 · see citing works

Role of fibroblast growth factors in bone regeneration

Charoenlarp, P., Rajendran, A. K., & Iseki, S. (2017) · Inflammation and Regeneration · doi:10.1186/s41232-017-0043-8 · Cited by 112 · see citing works

Dual release of growth factor from nanocomposite fibrous scaffold promotes vascularisation and bone regeneration in rat critical sized calvarial defect

Kuttappan, S., Mathew, D., Jo, J., Tanaka, R., Menon, D., Ishimoto, T., Nakano, T., Nair, S. V., Nair, M. B., & Tabata, Y. (2018) · Acta Biomaterialia · doi:10.1016/j.actbio.2018.07.050 · Cited by 111 · see citing works

Regulation of bone homeostasis: signaling pathways and therapeutic targets

Wu, Z., Li, W., Jiang, K., Lin, Z., Qian, C., Wu, M., Xia, Y., Li, N., Zhang, H., Xiao, H.-X., et al. (2024) · MedComm · doi:10.1002/mco2.657 · Cited by 115 · see citing works

Fibroblast growth factor expression during skeletal fracture healing in mice

Schmid, G. J., Kobayashi, C., Sandell, L. J., & Ornitz, D. M. (2009) · Developmental Dynamics · doi:10.1002/dvdy.21882 · Cited by 110 · see citing works

Runx2 regulates FGF2‐induced Bmp2 expression during cranial bone development

Choi, K., Kim, H.-J., Lee, M., Kwon, T., Nah, H., Furuichi, T., Komori, T., Nam, S., Kim, Y., Kim, H.-J., et al. (2005) · Developmental Dynamics · doi:10.1002/dvdy.20323 · Cited by 109 · see citing works

Composition Options for Tissue-Engineered Bone

Orban, J. M., Marra, K. G., & Hollinger, J. O. (2002) · Tissue Engineering · doi:10.1089/107632702760240454 · Cited by 109 · see citing works

Osteoinductive Molecules in Orthopaedics: Basic Science and Preclinical Studies

Yoon, S. T., & Boden, S. D. (2002) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-200202000-00005 · Cited by 108 · see citing works

FGF/FGFR signaling in bone formation: Progress and perspectives

Marie, P. J., Miraoui, H., & Sévère, N. (2012) · Growth Factors · doi:10.3109/08977194.2012.656761 · Cited by 107 · see citing works

The Role of Mast Cells in Bone Metabolism and Bone Disorders

Ragipoglu, D., Dudeck, A., Haffner‐Luntzer, M., Voß, M., Kroner, J., Ignatius, A. A., & Fischer, V. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00163 · Cited by 109 · see citing works

Selective inhibition of RANK blocks osteoclast maturation and function and prevents bone loss in mice

Kim, H., Choi, H. K., Shin, J. H., Kim, K., Huh, J. Y., Lee, S. A., Ko, C., Kim, H.-S., Shin, H.-I., Jeong, D., et al. (2009) · Journal of Clinical Investigation · doi:10.1172/jci36809 · Cited by 106 · see citing works

Priming Dental Pulp Stem Cells from Human Exfoliated Deciduous Teeth with Fibroblast Growth Factor-2 Enhances Mineralization Within Tissue-Engineered Constructs Implanted in Craniofacial Bone Defects

Novais, A., Lesieur, J., Sadoine, J., Slimani, L., Baroukh, B., Saubaméa, B., Schmitt, A., Vital, S. O., Poliard, A., Hélary, C., et al. (2019) · Stem Cells Translational Medicine · doi:10.1002/sctm.18-0182 · Cited by 103 · see citing works

The osteogenic transcription factor Runx2 regulates components of the fibroblast growth factor/proteoglycan signaling axis in osteoblasts

Teplyuk, N. M., Haupt, L. M., Ling, L., Dombrowski, C., Foong, K. M., Nathan, S. S., Lian, J. B., Stein, J. L., Stein, G. S., Cool, S. M., et al. (2009) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22108 · Cited by 103 · see citing works

The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization.

Hughes‐Fulford, M., & Li, C.-F. (2011) · Journal of Orthopaedic Surgery and Research · doi:10.1186/1749-799x-6-8 · Cited by 102 · see citing works

Heparan Sulfate-Dependent Signaling of Fibroblast Growth Factor 18 by Chondrocyte-Derived Perlecan

Chuang, C. Y., Lord, M. S., Melrose, J., Rees, M. D., Knox, S. M., Freeman, C. G., Iozzo, R. V., & Whitelock, J. M. (2010) · Biochemistry · doi:10.1021/bi1005199 · Cited by 102 · see citing works

Gain-of-function mutation in FGFR3 in mice leads to decreased bone mass by affecting both osteoblastogenesis and osteoclastogenesis.

Su, N., Sun, Q.-D., Li, C., Lu, X., Qi, H.-B., Chen, S., Yang, J., Du, X.-L., Zhao, L., He, Q., et al. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddp590 · Cited by 100 · see citing works

Molecular pathology of the fibroblast growth factor family

Krejci, P., Procházková, J., Bryja, V., Kozubík, A., & Wilcox, W. R. (2009) · Human Mutation · doi:10.1002/humu.21067 · Cited by 99 · see citing works

Stimulation of osteoprotegerin production is responsible for osteosclerosis in mice overexpressing TPO

Chagraoui, H., Tulliez, M., Smayra, T., Komura, E., Giraudier, S., Yun, T. J., Lassau, N., Vainchenker, W., & Wendling, F. (2003) · Blood · doi:10.1182/blood-2002-09-2839 · Cited by 97 · see citing works

The critical interplay between bone resorbing and bone forming cells

Lerner, U. H., Kindstedt, E., & Lundberg, P. (2019) · Journal Of Clinical Periodontology · doi:10.1111/jcpe.13051 · Cited by 99 · see citing works

Stat1 Controls Postnatal Bone Formation by Regulating Fibroblast Growth Factor Signaling in Osteoblasts

Xiao, L., Naganawa, T., Obugunde, E., Gronowicz, G., Ornitz, D. M., Coffin, J. D., & Hurley, M. M. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m314323200 · Cited by 95 · see citing works

The cartilage extracellular matrix as a transient developmental scaffold for growth plate maturation

Melrose, J., Shu, C., Whitelock, J. M., & Lord, M. S. (2016) · Matrix Biology · doi:10.1016/j.matbio.2016.01.008 · Cited by 96 · see citing works

Roles of FGF signaling in skeletal development and human genetic diseases

Lin, C. (2005) · Frontiers in bioscience · doi:10.2741/1671 · Cited by 94 · see citing works

Cellular and extracellular matrix of bone, with principles of synthesis and dependency of mineral deposition on cell membrane transport

Schlesinger, P. H., Blair, H. C., Stolz, D. B., Riazanski, V., Ray, E. C., Tourkova, I. L., & Nelson, D. J. (2019) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00120.2019 · Cited by 95 · see citing works

RUNX2-modifying enzymes: therapeutic targets for bone diseases

Kim, W., Shin, H.-L., Kim, B. S., Kim, H., & Ryoo, H. (2020) · Experimental & Molecular Medicine · doi:10.1038/s12276-020-0471-4 · Cited by 96 · see citing works

FGF and FGFR signaling in chondrodysplasias and craniosynostosis

Marie, P. J., Coffin, J. D., & Hurley, M. M. (2005) · Journal of Cellular Biochemistry · doi:10.1002/jcb.20582 · Cited by 86 · see citing works

FGF2 stimulates osteogenic differentiation through ERK induced TAZ expression

Byun, M. R., Kim, A. R., Hwang, J.-H., Kim, K. M., Hwang, E. S., & Hong, J. H. (2013) · Bone · doi:10.1016/j.bone.2013.09.024 · Cited by 86 · see citing works

Mesoporous Calcium Silicate Nanoparticles with Drug Delivery and Odontogenesis Properties

Huang, C.-Y., Huang, T., Kao, C., Wu, Y.-H. A., Chen, W.-C., & Shie, M. (2016) · Journal of Endodontics · doi:10.1016/j.joen.2016.09.012 · Cited by 86 · see citing works

Receptor Tyrosine Kinases Inhibit Bone Morphogenetic Protein-Smad Responsive Promoter Activity and Differentiation of Murine MC3T3-E1 Osteoblast-like Cells

Nakayama, K., Tamura, Y., Suzawa, M., Harada, S.-I., Fukumoto, S., Kato, M., Miyazono, K., Rodan, G. A., Takeuchi, Y., & Fujita, T. (2003) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2003.18.5.827 · Cited by 85 · see citing works

MT1-MMP Inactivates ADAM9 to Regulate FGFR2 Signaling and Calvarial Osteogenesis

Chan, K. M., Wong, H. L. X., Jin, G., Liu, B., Cao, R., Cao, Y., Lehti, K., Tryggvason, K., & Zhou, Z. (2012) · Developmental Cell · doi:10.1016/j.devcel.2012.04.014 · Cited by 85 · see citing works

Reduced expression and function of bone morphogenetic protein‐2 in bones of Fgf2 null mice

Naganawa, T., Xiao, L., Coffin, J. D., Doetschman, T., Sabbieti, M. G., Agas, D., & Hurley, M. M. (2007) · Journal of Cellular Biochemistry · doi:10.1002/jcb.21589 · Cited by 79 · see citing works

Over‐expression of fibroblast growth factor‐2 causes defective bone mineralization and osteopenia in transgenic mice

Sobue, T., Naganawa, T., Xiao, L., Okada, Y., Tanaka, Y., Ito, M., Okimoto, N., Nakamura, T., Coffin, J. D., & Hurley, M. M. (2005) · Journal of Cellular Biochemistry · doi:10.1002/jcb.20389 · Cited by 68 · see citing works

In vivo and in vitro comparison of the effects of FGF-2 null and haplo-insufficiency on bone formation in mice

Naganawa, T., Xiao, L., Abogunde, E., Sobue, T., Kalajzić, I., Sabbieti, M. G., Agas, D., & Hurley, M. M. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.10.215 · Cited by 61 · see citing works

Exported 18-kDa Isoform of Fibroblast Growth Factor-2 Is a Critical Determinant of Bone Mass in Mice

Xiao, L., Liu, P., Li, X., Doetschman, T., Coffin, J. D., Drissi, H., & Hurley, M. M. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m804900200 · Cited by 58 · see citing works

Fibroblast growth factor 2 positively regulates expression of activating transcription factor 4 in osteoblasts

Fei, Y., Xiao, L., & Hurley, M. M. (2009) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.11.059 · Cited by 15 · see citing works