The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
The prevalence and distribution of major depression in a national community sample: the National Comorbidity Survey
Abstract
OBJECTIVE: Major depression is a frequent and disabling psychiatric disorder in the United States. This report examines the prevalence and risk factor profile of both pure and comorbid major depression according to data from the National Comorbidity Survey. METHOD: To estimate the prevalence of psychiatric comorbidity in the United States, a national sample of 8,098 persons 15-54 years of age from the 48 conterminous states was surveyed with a modified version of the Composite International Diagnostic Interview. RESULTS: From the survey data the prevalence of current (30-day) major depression was estimated to be 4.9%, with a relatively higher prevalence in females, young adults, and persons with less than a college education. The prevalence estimate for lifetime major depression was 17.1%, with a similar demographic distribution. Both 30-day and lifetime prevalence estimates were higher than estimates from the earlier Epidemiologic Catchment Area study. When pure major depression was compared with major depression co-occurring with other psychiatric disorders, the risk factor profiles exhibited clear differences. CONCLUSIONS: These findings suggest a greater burden of major depression in community-dwelling persons than has been estimated from previous community samples. The risk factor profile showed significant differences between persons with pure and combined major depression.
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“Of course, depression is common among women, and the ages at which women are most likely to have children are those at which women seem to have the highest rates of depression across the life-span [56,57].”
From Perinatal mental illness: Definition, description and aetiology (2014) · cites this paper as [56]
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Descriptive Epidemiology of a Depressive Syndrome in a Western Canadian Community Population
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“Depression is a highly prevalent disorder, with population-based studies suggesting a lifetime prevalence for unipolar depression of 15%, and up to 25% in women [12-14].”
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Depression in patients of myocardial infarction--a cross-sectional study in northern India.
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BackgroundA Review of Lesbian Depression and Anxiety
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“7% of women).(13,14) However, since they relied on questionnaires to identify women with probable DD, it is likely that the group of women who they identified as having a probable DD was actually a composite mixture of women with different depression diagnoses.”
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Rate and Predictors of Persistent Major Depressive Disorder in a Nationally Representative Sample
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“Among people classified as having depression in 1995–1996, significant bivariate associations were found between depression in 2004–2006 the following baseline variables: being female (v2 = 12.78, p\ 0.0001), having an income below $15,000 (v2 = 4.02, p = 0.045), having less than a high school…”
BackgroundMethodInfluentialMental health status and gender as risk factors for onset of physical illness over 10 years
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Stress-evoked opioid release inhibits pain in major depressive disorder
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“This is considerably higher than the prevalence of depressive disorders in the general population (42).”
BackgroundAdenylyl cyclase 7 and neuropsychiatric disorders: A new target for depression?
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“In humans, major depressive episodes are almost twice more common in women than in men [3,4].”
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“6% reported for that age group for the NCS.(49) Almost 60% of the Medicare patients under age 65 in our study exhibited clinically significant depressive symptoms during the previous week as identified by the GDS.”
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Metadata
- Authors
- Blazer, D. G., Kessler, R. C., McGonagle, K. A., & Swartz, M. S.
- Affiliations
- Duke Medical Center (US)
- Venue
- American Journal of Psychiatry
- Published
- 1994-07-01
- Volume
- 151
- Issue
- 7
- Pages
- 979-986
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2181560023
- Cited by
- 1,485
- References
- 24
- Citations by year
- 2026: 7 · 2025: 11 · 2024: 20 · 2023: 17 · 2022: 20 · 2021: 16 · 2020: 26 · 2019: 33 · 2018: 38 · 2017: 42 · 2016: 50 · 2015: 49 · 2014: 57 · 2013: 71 · 2012: 57
- FWCI
- 39.36
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (R01MH046376, NIMH MH-00507, MH 46376)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- major depressive disorder, prevalence, psychiatric comorbidity, risk factors, lifetime prevalence, community-dwelling adults, sex differences, young adults, educational attainment, National Comorbidity Survey
- MeSH terms
- Adolescent, Adult, Age Factors, Mental Disorders, Depressive Disorder, Educational Status, Female, Health Surveys, Humans, Male, Middle Aged, Psychiatric Status Rating Scales, Risk Factors, Sex Factors, United States, Comorbidity, Prevalence
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