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Cited by 536

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Randomized Controlled Trial of Motivational Interviewing, Cognitive Behavior Therapy, and Family Intervention for Patients With Comorbid Schizophrenia and Substance Use Disorders

Barrowclough, Christine, Haddock, Gillian, Tarrier, Nicholas, Lewis, Shôn W., Moring, Jan, O’Brien, Rob, Schofield, Nichola, McGovern, John·2001·American Journal of Psychiatry
DOI 10.1176/appi.ajp.158.10.1706
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Abstract

OBJECTIVE: Comorbidity of substance abuse disorders with schizophrenia is associated with a greater risk for serious illness complications and poorer outcome. Methodologically sound studies investigating treatment approaches for patients with these disorders are rare, although recommendations for integrated and comprehensive treatment programs abound. This study investigates the relative benefit of adding an integrated psychological and psychosocial treatment program to routine psychiatric care for patients with schizophrenia and substance use disorders. METHOD: The authors conducted a randomized, single-blind controlled comparison of routine care with a program of routine care integrated with motivational interviewing, cognitive behavior therapy, and family or caregiver intervention. RESULTS: The integrated treatment program resulted in significantly greater improvement in patients' general functioning than routine care alone at the end of treatment and 12 months after the beginning of the study. Other benefits of the program included a reduction in positive symptoms and in symptom exacerbations and an increase in the percent of days of abstinence from drugs or alcohol over the 12-month period from baseline to follow-up. CONCLUSIONS: These findings demonstrate the effectiveness of a program of routine care integrated with motivational interviewing, cognitive behavior therapy, and family intervention over routine psychiatric care alone for patients with comorbid schizophrenia and alcohol or drug abuse or dependence.

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Citations

Cites

Show all 4 references

Research works printed but not linked: 22

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Cited by

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Metadata

Authors
Barrowclough, C., Haddock, G., Tarrier, N., Lewis, S. W., Moring, J., O’Brien, R., Schofield, N., & McGovern, J.
Venue
American Journal of Psychiatry
Publisher
American Psychiatric Association Publishing
Published
2001-10-01
Volume
158
Issue
10
Pages
1706-1713
ISSN
  • 0002-953X (ISSN-L)
  • 1535-7228
DOI
10.1176/appi.ajp.158.10.1706
OpenAlex
W2107406184
Cited by
536
References
4
FWCI
18.24
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Randomized Controlled Trial of Motivational Interviewing, Cognitive Behavior Therapy, and Family Intervention for Patients With Comorbid Schizophrenia and Substance Use Disorders. https://app.cochat.ai/papers/10.1176/appi.ajp.158.10.1706
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Barrowclough, C., Haddock, G., Tarrier, N., Lewis, S. W., Moring, J., O’Brien, R., Schofield, N., & McGovern, J. (2001). Randomized Controlled Trial of Motivational Interviewing, Cognitive Behavior Therapy, and Family Intervention for Patients With Comorbid Schizophrenia and Substance Use Disorders. American Journal of Psychiatry. https://doi.org/10.1176/appi.ajp.158.10.1706

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.