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Systematic Review of Psychological Approaches to the Management of Neuropsychiatric Symptoms of Dementia
Open accessAbstract
OBJECTIVE: The authors systematically reviewed the literature on psychological approaches to treating the neuropsychiatric symptoms of dementia. METHOD: Reports of studies that examined effects of any therapy derived from a psychological approach that satisfied prespecified criteria were reviewed. Data were extracted, the quality of each study was rated, and an overall rating was given to each study by using the Oxford Centre for Evidence-Based Medicine criteria. RESULTS: A total of 1,632 studies were identified, and 162 satisfied the inclusion criteria for the review. Specific types of psychoeducation for caregivers about managing neuropsychiatric symptoms were effective treatments whose benefits lasted for months, but other caregiver interventions were not. Behavioral management techniques that are centered on individual patients' behavior or on caregiver behavior had similar benefits, as did cognitive stimulation. Music therapy and Snoezelen, and possibly sensory stimulation, were useful during the treatment session but had no longer-term effects; interventions that changed the visual environment looked promising, but more research is needed. CONCLUSIONS: Only behavior management therapies, specific types of caregiver and residential care staff education, and possibly cognitive stimulation appear to have lasting effectiveness for the management of dementia-associated neuropsychiatric symptoms. Lack of evidence regarding other therapies is not evidence of lack of efficacy. Conclusions are limited because of the paucity of high-quality research (only nine level-1 studies were identified). More high-quality investigation is needed.
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“According to Livingston et al. [45], agitation in dementia is associated with poorer quality of life and impairs the engagement in daily activities and relationships.”
From Nonpharmacological Interventions to Reduce Behavioral and Psychological Symptoms of Dementia: A Systematic Review (2015) · cites this paper as [45]
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Cites
Lyketsos, C. G., Lopez, O., Jones, B., Fitzpatrick, A. L., Breitner, J., & DeKosky, S. (2002) · JAMA · doi:10.1001/jama.288.12.1475 · Cited by 2,049
Self-citationClock-drawing: is it the ideal cognitive screening test?
Shulman, K. I. (2000) · International Journal of Geriatric Psychiatry · doi:10.1002/1099-1166(200006)15:6 · Cited by 1,354
Moher, D., Jadad, A. R., Nichol, G., Penman, M., Tugwell, P., & Walsh, S. (1995) · Controlled Clinical Trials · doi:10.1016/0197-2456(94)00031-w · Cited by 1,308
Lyketsos, C. G., Steinberg, M., Tschanz, J. T., Norton, M. C., Steffens, D. C., & Breitner, J. C. S. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.5.708 · Cited by 1,144
Self-citationEfficacy of an evidence-based cognitive stimulation therapy programme for people with dementia
Spector, A. E., Thorgrimsen, L., Woods, B. T., Royan, L., Davies, S., Butterworth, M., & Orrell, M. W. (2003) · The British Journal of Psychiatry · doi:10.1192/bjp.183.3.248 · Cited by 880
A Family Intervention to Delay Nursing Home Placement of Patients With Alzheimer Disease
Mittelman, M. S. (1996) · JAMA · doi:10.1001/jama.1996.03540210033030 · Cited by 870
Exercise Plus Behavioral Management in Patients With Alzheimer Disease
Teri, L. L., Gibbons, L. E., McCurry, S. M., Logsdon, R. G., Büchner, D. M., Barlow, W. E., Kukull, W. A., LaCroix, A. Z., McCormick, W. C., & Larson, E. B. (2003) · JAMA · doi:10.1001/jama.290.15.2015 · Cited by 765
Finkel, S. I., Miller, S., Silva, J. C. E., Cohen, G. D., & Sartorius, N. (1997) · International Psychogeriatrics · doi:10.1017/s1041610297003943 · Cited by 651
Behavioral Treatment of Depression in Dementia Patients: A Controlled Clinical Trial
Teri, L. L., Logsdon, R. G., Uomoto, J. M., & McCurry, S. M. (1997) · The Journals of Gerontology Series B · doi:10.1093/geronb/52b.4.p159 · Cited by 641
Gerdner, L. A. (2000) · International Psychogeriatrics · doi:10.1017/s1041610200006190 · Cited by 373
Research works printed but not linked: 5
- Korb C: The influence of music therapy on patients with a diagnosed dementia. Can J Music Therapy 1997; 5:26–54
- Ghatak R: Effects of an intervention program on dementia patients and their caregivers. Caring 1994; 13:34–39
- Kempenaar L, McNamara C, Creaney B: Sensory stimulation work with carers in the community. J Dementia Care 2001; 9:16–17
- Gorzelle GJ, Kaiser K, Camp CJ: Montessori-based training makes a difference for home health workers and their clients. Caring 2003; 22:40–42
- Webber P, Breuer W, Lindeman D: Alzheimer’s special care units vs integrated nursing homes: a comparison of resident outcomes. J Clin Geropsychol 1995; 1:189–205
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Rousseau, T. (2011) · Elsevier eBooks · doi:10.1016/b978-2-294-70950-0.00004-3
de Oliveira, A. M. (2018) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.5.2018.tde-05122018-132604
Buttaro, T. M. (2012) · Wiley eBooks · doi:10.1002/9781118704769.ch8
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Foidel, S. E. (2019) · Springer eBooks · doi:10.1007/978-3-030-11268-4_5
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Lichtwarck, B. (2019) · NORA - Norwegian Open Research Archives · doi:10.13140/rg.2.2.20978.22727
Ageing in Better Mental Health
Cordella, M., & Poiani, A. (2021) · International perspectives on aging · doi:10.1007/978-3-030-60071-6_4
Forstmeier, S., & Roth, T. (2017) · Springer eBooks · doi:10.1007/978-3-662-54849-3_4
Gutzmann, H., & Mahlberg, R. (2008) · Springer eBooks · doi:10.1007/978-3-540-35486-4_16
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Tampi, R. R., Tampi, D. J., Canio, W. C., Alag, P., Dasarathy, D., & Dey, J. (2018) · Springer eBooks · doi:10.1007/978-3-319-73078-3_16
Hampel, H. J., & Pantel, J. (2011) · Springer eBooks · doi:10.1007/978-3-642-03637-8_47
Current awareness in geriatric psychiatry
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Bibliography: Geriatric Psychiatry
(2013) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/appi.focus.11.1.73
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Stern, C., & Gibb, H. (2011) · JBI Library of Systematic Reviews · doi:10.11124/jbisrir-2011-88
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Non-pharmacological treatment for the patients with dementia and the evidence of it
愛子, 大., & 伸一郎, 前. (2020) · Nippon Ronen Igakkai Zasshi Japanese Journal of Geriatrics · doi:10.3143/geriatrics.57.40
Disease-specific neurorehabilitation systems
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Gutzmann, H., & Mahlberg, R. (2011) · Springer eBooks · doi:10.1007/978-3-642-19795-6_17
(2014) · Elsevier eBooks · doi:10.1016/b978-3-437-31683-8.16001-1
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The Use of Recall on the Management of Behaviours Associated with Dementia
(2009) · The JBI Database of Systematic Reviews and Implementation Reports · doi:10.11124/01938924-200907161-00010
Bibliography: Geriatric Psychiatry
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“20,22 The BEHAV5+ is a 6-item scale that screens for the following behaviors exhibited by the patient within the past month: agitation, hallucinations, irritability, suspiciousness, indifference, and sleep problems.”
BackgroundReichenberg, L. W., & Seligman, L. (2016) · Wiley eBooks · doi:10.1002/9781394259465.ch18
Mapping the Impact: A Comprehensive Review of Art-Based Interventions for Dementia (2000-2022)
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Alenezi, A. T., Alenezi, A., Alruwaili, S. S. Q., Alruwaili, M. F., Alenzi, S. H., Alenzi, A. F., Alenzi, B. H., Siddiq, A. S., Alanazi, A. F., Alruwaili, M. T., et al. (2023) · Journal of Survey in Fisheries Sciences · doi:10.53555/sfs.v10i5.2313
Sönmez, D., & Hocaoğlu, Ç. (2024) · Anadolu Kliniği Tıp Bilimleri Dergisi · doi:10.21673/anadoluklin.1476946
(2015) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615378746.bm02
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Bourgeois, J. A., Seaman, J. S., Servis, M. E., & Hategan, A. (2012) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615378333.lg08
(2022) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615379729.lg05
Deprez, L., Didone, V., Pyrovolaki, E., & Adam, S. (2025) · Journal of Gerontological Nursing · doi:10.3928/00989134-20250627-01
Chapter 15. Psychiatric Disorders in People With Dementia
Steinberg, M., & Lyketsos, C. G. (2009) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781585628940.lg15
Self-citationChapter 17. Behavioral and Environmental Management
Hilgeman, M. M., Burgio, L. D., & Allen, R. S. (2009) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781585628940.lg17
Thompson, A. G. B. (2014) · UCL Discovery (University College London)
Rommerskirch‐Manietta, M., Manietta, C., Purwins, D., Braunwarth, J. I., Quasdorf, T., & Roes, M. (2024) · Figshare · doi:10.6084/m9.figshare.26613335
Chapter 8. Psychosocial Therapies
McKenzie, G. L., & Teri, L. L. (2011) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781585629527.lg08
Chaichumni, N., Pensuksan, W. C., Sommaluan, S., Suvanchot, K. S., Hamtanon, P., & Kenbubpha, K. (2026) · Psychogeriatrics · doi:10.1111/psyg.70135
Besozzi, A. (2017) · theses.fr (ABES) · doi:10.70675/f92357ddz6f18z44f5z850azc3e731dfcb69
Balvert, S. C. E., Butterbrod, E., Dröes, R. M., Heymans, M. W., Scherder, E., & Milders, M. V. (2026) · BMC Geriatrics · doi:10.1186/s12877-026-07634-0
“Activity-based components, such as engaging the person with dementia in meaningful shared activities, are grounded in the principle that social and cognitive stimulation can positively affect the wellbeing of both the person with dementia and the informal caregiver [27, 28].”
Zhu, Y., Jafari, Z., Kolb, B. E., & Mohajerani, M. H. (2026) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2026.107004
Behavioral and Psychological Symptoms of Dementia
Draper, B., & Wand, A. P. F. (2017) · Springer eBooks · doi:10.1007/978-981-287-082-7_88
Vreeland, R. F. (2015) · UA Campus Repository (The University of Arizona)
Backhouse, T. (2014) · UEA Digital Repository (University of East Anglia)
Zaburzenia psychiczne w przebiegu zespołów otępiennych – znaczenie kliniczne i zasady postępowania
Sobów, T. (2012) · DOAJ (DOAJ: Directory of Open Access Journals)
de Vugt, M. E., & Vernooij-Dassen, M. J. F. J. (2009) · Bohn Stafleu van Loghum eBooks · doi:10.1007/978-90-313-8061-9_12
Metadata
- Authors
- Livingston, G., Johnston, K., Katona, C., Paton, J., Lyketsos, C. G., & Old Age Task Force of the World Federation of Biological Psychiatry
- Affiliations
- University College London (GB)
- Corresponding author
- Livingston, Gill
- Venue
- American Journal of Psychiatry
- Published
- 2005-11-01
- Volume
- 162
- Issue
- 11
- Pages
- 1996-2021
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2150798548
- Cited by
- 591
- References
- 172
- Citations by year
- 2026: 6 · 2025: 8 · 2024: 14 · 2023: 8 · 2022: 17 · 2021: 16 · 2020: 10 · 2019: 28 · 2018: 21 · 2017: 39 · 2016: 38 · 2015: 28 · 2014: 46 · 2013: 47 · 2012: 56
- FWCI
- 3.50
- Type
- journal article
- Language
- en
- Open access
- green
- discovery.ucl.ac.uk
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Kent Academic Repository (University of Kent) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Geriatrics and Gerontology › Geriatric Care and Nursing Homes
- Social Sciences › Psychology › Clinical Psychology › Art Therapy and Mental Health
- Keywords
- psychological intervention, caregiver interventions, cognitive stimulation therapy, music therapy, Snoezelen, sensory stimulation, long-term treatment effectiveness
- MeSH terms
- Behavior Therapy, Dementia, Humans, Person-Centered Psychotherapy, Patient Education as Topic, Psychotherapy, Research Design, Cognitive Behavioral Therapy, Randomized Controlled Trials as Topic, Treatment Outcome, Caregivers, Guidelines as Topic, Evidence-Based Medicine
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