Anxiety, depression, and quality of life in Parkinson's disease
Open accessAbstract
Parkinson's disease has a major impact on quality of life. This cross-sectional study assessed 43 idiopathic Parkinson's disease patients in order to evaluate the impact of Parkinson's disease severity (Hoehn and Yahr scale), anxiety, and depression (Hospital Anxiety and Depression Scale) on quality of life (Short Form-36 Health Survey questionnaire). Hospital Anxiety and Depression Scale and Short Form-36 Health Survey scores were significantly correlated in Hoehn and Yahr stage 2 Parkinson's disease (n=33), and anxiety had a strong correlation with physical score. Multivariate analysis (n=43) revealed that anxiety was the strongest predictor of quality of life. Anxious and depressive symptoms have a different meaning in Parkinson's disease, and both must be routinely assessed in order to optimize quality of life.
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Anxiety and depression are thought to be the strongest PD quality of life predictors.
“are thought to be the strongest PD quality of life predictors (Rahman et al., 2008”
From Remote delivery of psychological interventions for Parkinson's disease. (2018) · cites this paper as Quelhas and Costa, 2009
The Multiple Regression Analysis identifies the combined anxiety-and-depression scale score as the strongest predictor of global quality of life. But when the symptoms were analyzed separately, anxiety had the largest coefficient and depression's was nonsignificant. The paper therefore does not support calling both symptoms individually the strongest predictors. (LLM, conf=0.88)
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Cognitive–Behavioral Treatment for Anxiety and Depression in Parkinson’s Disease
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Impact of ethnicity on mood disorders in Parkinson's disease
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Assessment in Geriatric Settings
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What Predicts Hospital Admissions in Community-Dwelling People With Parkinsonism?
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Síntomas no motores en pacientes con enfermedad de Parkinson
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Meditation and breathwork on anxiety in Parkinson's disease: A pilot randomized controlled trial
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Alprazolam Reduces Freezing of Gait (FOG) and Improves FOG-Related Gait Deficiencies
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- Authors
- Quelhas, R., & Costa, M.
- Affiliations
- Hospital Pedro Hispano (PT)
- ORCID
- Costa, Manuela
- Venue
- The Journal of Neuropsychiatry and Clinical Neurosciences
- Published
- 2009-10
- Volume
- 21
- Issue
- 4
- Pages
- 413-419
- ISSN
- 0895-0172 (ISSN-L)
- 1545-7222
- OpenAlex
- W2091884120
- Cited by
- 100
- References
- 24
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 5 · 2023: 9 · 2022: 3 · 2021: 8 · 2020: 5 · 2019: 10 · 2018: 7 · 2017: 8 · 2016: 7 · 2015: 6 · 2014: 7 · 2013: 7 · 2012: 6
- FWCI
- 2.35
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Neuropsychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
- Health Sciences › Medicine › Neurology › Neurological disorders and treatments
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Keywords
- Parkinson's disease, anxiety, depression, quality of life, disease severity, Hoehn and Yahr stage, physical function, psychosocial impact
- MeSH terms
- Activities of Daily Living, Aged, Aged, 80 and over, Anxiety, Cross-Sectional Studies, Depression, Female, Health Status, Humans, Male, Middle Aged, Parkinson Disease, Psychiatric Status Rating Scales, Quality of Life, Surveys and Questionnaires, Regression Analysis, Severity of Illness Index, Multivariate Analysis, Statistics, Nonparametric
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