Cited by 100Parkinson's Disease Mechanisms and TreatmentsNeurological disorders and treatmentsCancer survivorship and care

Anxiety, depression, and quality of life in Parkinson's disease

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Quelhas, Rosa, Costa, Manuela·2009·The Journal of Neuropsychiatry and Clinical Neurosciences

Abstract

Parkinson's disease has a major impact on quality of life. This cross-sectional study assessed 43 idiopathic Parkinson's disease patients in order to evaluate the impact of Parkinson's disease severity (Hoehn and Yahr scale), anxiety, and depression (Hospital Anxiety and Depression Scale) on quality of life (Short Form-36 Health Survey questionnaire). Hospital Anxiety and Depression Scale and Short Form-36 Health Survey scores were significantly correlated in Hoehn and Yahr stage 2 Parkinson's disease (n=33), and anxiety had a strong correlation with physical score. Multivariate analysis (n=43) revealed that anxiety was the strongest predictor of quality of life. Anxious and depressive symptoms have a different meaning in Parkinson's disease, and both must be routinely assessed in order to optimize quality of life.

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Crossref · 10.1176/jnp.2009.21.4.413

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  • Anxiety and depression are thought to be the strongest PD quality of life predictors.

    “are thought to be the strongest PD quality of life predictors (Rahman et al., 2008”

    From Remote delivery of psychological interventions for Parkinson's disease. (2018) · cites this paper as Quelhas and Costa, 2009

    The Multiple Regression Analysis identifies the combined anxiety-and-depression scale score as the strongest predictor of global quality of life. But when the symptoms were analyzed separately, anxiety had the largest coefficient and depression's was nonsignificant. The paper therefore does not support calling both symptoms individually the strongest predictors. (LLM, conf=0.88)

    Experimental — accuracy not yet measured

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Research works printed but not linked: 2

  1. Ferreira PL: Criac ¸a ˜o da versa ˜o portuguesa do MOS SF-36: parte I-adaptac ¸a ˜o cultural e linguı ´stica. Acta Med Port 2000; 13:55-66
  2. Ferreira PL: Criac ¸a ˜o da versa ˜o portuguesa do MOS SF-36: parte II-testes de validac ¸a ˜o. Acta Med Port 2000; 13:119 -127

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Authors
Quelhas, R., & Costa, M.
Affiliations
Hospital Pedro Hispano (PT)
Venue
The Journal of Neuropsychiatry and Clinical Neurosciences
Published
2009-10
Volume
21
Issue
4
Pages
413-419
ISSN
  • 0895-0172 (ISSN-L)
  • 1545-7222
OpenAlex
W2091884120
Cited by
100
References
24
Citations by year
2026: 3 · 2025: 4 · 2024: 5 · 2023: 9 · 2022: 3 · 2021: 8 · 2020: 5 · 2019: 10 · 2018: 7 · 2017: 8 · 2016: 7 · 2015: 6 · 2014: 7 · 2013: 7 · 2012: 6
FWCI
2.35
Type
journal article
Language
en
Open access
Locations
  • Journal of Neuropsychiatry (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
  • Health Sciences › Medicine › Neurology › Neurological disorders and treatments
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
Keywords
Parkinson's disease, anxiety, depression, quality of life, disease severity, Hoehn and Yahr stage, physical function, psychosocial impact
MeSH terms
Activities of Daily Living, Aged, Aged, 80 and over, Anxiety, Cross-Sectional Studies, Depression, Female, Health Status, Humans, Male, Middle Aged, Parkinson Disease, Psychiatric Status Rating Scales, Quality of Life, Surveys and Questionnaires, Regression Analysis, Severity of Illness Index, Multivariate Analysis, Statistics, Nonparametric

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