Management and 1-Year Outcomes of Patients With Atrial Fibrillation in the Middle East: Gulf Survey of Atrial Fibrillation Events
Abstract
We describe management and outcomes of patients with nonvalvular atrial fibrillation (AF) in the Middle East. Consecutive patients with AF presenting to emergency departments (EDs) were prospectively enrolled. Among 1721 patients with nonvalvular AF, mean age was 59 ± 16 years and 44% were women. Comorbidities were common such as hypertension (59%), diabetes (33%), and coronary artery disease (33%). Warfarin was not prescribed to 40% of patients with Congestive heart failure, Hypertension, Age, Diabetes mellitus, Stroke/TIA 2 score of ≥2. One-year rates of stroke/transient ischemic attack (TIA) and all-cause mortality were 4.2% and 15.3%, respectively. Warfarin use at hospital–ED discharge was independently associated with lower 1-year rate of stroke/TIA (odds ratio [OR], 0.38; 95% confidence interval [CI], 0.17-0.85; P = .015) and all-cause mortality (OR, 0.51; 95% CI, 0.32-0.83; P = .006). Prior history of heart failure and peripheral vascular disease was independent mortality predictors. Our patients are relatively young with significant cardiovascular risk. Their anticoagulation treatment is suboptimal, and 1-year all-cause mortality and stroke/TIA event rates are relatively high.
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Female sex is a well-known risk factor for heart failure with preserved ejection fraction.
“In addition, female sex is a well-known risk factor for HF with preserved ejection fraction, possibly attributable to hemodynamic changes and cardiovascular remodelling post menopause.165,166”
From Atrial fibrillation in women: epidemiology, pathophysiology, presentation, and prognosis (2016) · cites this paper as [165]
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Atrial fibrillation in women: epidemiology, pathophysiology, presentation, and prognosis
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- Authors
- Zubaid, M., Rashed, W. A., Alsheikh-Ali, A. A., Al-Zakwani, I., AlMahmeed, W., Shehab, A., Sulaiman, K., Qudaimi, A. A., Asaad, N., & Amin, H.
- Affiliations
- Kuwait University (KW)
- Mubarak Al Kabeer Hospital (KW)
- Tufts University (US)
- Sultan Qaboos University (OM)
- Shaikh Khalifa Medical City (AE)
- United Arab Emirates University (AE)
- Royal Hospital (OM)
- Department of Medicine, Al Thawra Hospital, Sana’a, Yemen
- Hamad Medical Corporation (QA)
- Ministry of Health (BH)
- ORCID
- Venue
- Angiology
- Publisher
- SAGE Publications
- Published
- 2014-06-05
- Volume
- 66
- Issue
- 5
- Pages
- 464-471
- ISSN
- 0003-3197 (ISSN-L)
- 1940-1574
- OpenAlex
- W2003181174
- Cited by
- 29
- References
- 30
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 2 · 2023: 3 · 2022: 2 · 2021: 1 · 2020: 3 · 2019: 1 · 2018: 1 · 2017: 3 · 2016: 4 · 2015: 5
- FWCI
- 2.74
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Angiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Health Sciences › Medicine › Epidemiology › Acute Ischemic Stroke Management
- Health Sciences › Medicine › Internal Medicine › Venous Thromboembolism Diagnosis and Management
- Keywords
- non-valvular atrial fibrillation, anticoagulation, stroke prevention, transient ischemic attack, all-cause mortality, one-year outcomes, emergency department patients, cardiovascular risk factors, heart failure, peripheral vascular disease, Middle East
- MeSH terms
- Adult, Age Factors, Aged, Anticoagulants, Atrial Fibrillation, Ischemic Attack, Transient, Emergency Service, Hospital, Female, Humans, Male, Middle Aged, Middle East, Patient Discharge, Practice Patterns, Physicians', Platelet Aggregation Inhibitors, Prospective Studies, Registries, Risk Factors, Time Factors, Warfarin, Comorbidity, Multivariate Analysis, Chi-Square Distribution, Logistic Models, Odds Ratio, Treatment Outcome, Practice Guidelines as Topic, Risk Assessment, Guideline Adherence, Stroke
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