Effectiveness of psychoeducation for depression: A systematic review
Abstract
Objective: Pharmacological treatment is considered indispensable to major depressive disorder. In spite of this, a significant number of patients do not respond adequately to treatment based only on medication, presenting high relapse and recurrence rates. Therefore, psychosocial interventions, such as psychoeducation, have been increasingly recognized as an essential component in the treatment of depression, associated with pharmacological strategies. Thus, the aim of the present systematic review was to evaluate the effectiveness of psychoeducation for patients with unipolar depression, analyzing the evidence from the literature. Method: Searches were undertaken from April to October 2012 in LILACS, PsycINFO, PubMed, SCOPUS and ISI Web of Knowledge with keywords including ‘psychoeducation’, ‘psychoeducational intervention’ and ‘depression’, with no restriction regarding publishing dates. Results: Fifteen studies were included in the review, 13 of which evaluated the effectiveness of psychoeducation for patients with depression: 10 papers evaluated in-person psychoeducation approaches and three papers evaluated long-distance approaches. In addition to these 13 papers, one evaluated psychoeducational interventions for patients’ families and patients’ responses and another evaluated psychoeducational interventions for patients’ families and families’ responses. Findings suggest that increased knowledge about depression and its treatment is associated with better prognosis in depression, as well as with the reduction of the psychosocial burden for the family. Conclusions: Psychoeducation is a psychosocial treatment that has been well documented as an adjunct to pharmacological therapy. However, there are only a few studies regarding its effectiveness on adult patients with major depressive disorder. Although the publications in this area are still very limited, the articles selected in this review suggest that psychoeducation is effective in improving the clinical course, treatment adherence, and psychosocial functioning of depressive patients.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Psychoeducation is beneficial as an adjunctive treatment for depression and is readily translated into web-format.
“Psychoeducation is beneficial as an adjunctive treatment for depression and is readily translated into web-format.35”
Group psychoeducation is more effective in reducing relapse rate than individual education.
“In a study by de Souza Tursi (2013), it became clear that group psychoeducation is more effective in reducing relapse rate than individual education.”
From A Novel Psychological Group Intervention Targeting Appearance-Related Distress Among People With a Visible Disfigurement (Inside Out): A Case Study (2023) · cites this paper as de Souza Tursi (2013)
Cites
Journal of Clinical Psychiatry
(2018) · Journal of Clinical Psychiatry · doi:10.5505/kpd · Cited by 13,703 · see citing works
Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study
Murray, C. J., & Lopez, A. D. (1997) · The Lancet · doi:10.1016/s0140-6736(96)07495-8 · Cited by 4,492 · cited 1× · see citing works
“Forecasts indicate that, in 2020, depression will be the second major cause of global losses among all ages and sexes (Fleck et al., 2009; Kessler et al., 2005; Murray and Lopez, 1997).”
BackgroundDepression, chronic diseases, and decrements in health: results from the World Health Surveys
Moussavi, S., Chatterji, S., Verdes, E., Tandon, A., Patel, V., & Ustun, B. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61415-9 · Cited by 4,070 · see citing works
Davenport, Y. B., Adland, M. L., Gold, P. W., & Goodwin, F. K. (1984) · The Lancet · doi:10.1016/s0140-6736(84)92810-1 · Cited by 2,925 · see citing works
The functioning and well-being of depressed patients. Results from the Medical Outcomes Study
Wells, K. B. (1989) · JAMA · doi:10.1001/jama.262.7.914 · Cited by 2,826 · see citing works
The Functioning and Well-being of Depressed Patients: Results From the Medical Outcomes Study
Wells, K. B. (1989) · JAMA · doi:10.1001/jama.1989.03430070062031 · Cited by 2,130 · cited 2× · see citing works
“Email: juruena@fmrp.usp.br Australian & New Zealand Journal of Psychiatry, 47(11) This disorder often leads to functional disability, causing significant social, work and family problems for the patient (Broadhead et al., 1990; Wells et al., 1989).”
BackgroundPrevalence and Treatment of Mental Disorders, 1990 to 2003
Kessler, R. C., Demler, O., Frank, R. G., Olfson, M., Pincus, H. A., Walters, E. E., Wang, P., Wells, K. B., & Zaslavsky, A. M. (2005) · New England Journal of Medicine · doi:10.1056/nejmsa043266 · Cited by 1,910 · see citing works
Transduction of psychosocial stress into the neurobiology of recurrent affective disorder
(1992) · American Journal of Psychiatry · doi:10.1176/ajp.149.8.999 · Cited by 1,848 · see citing works
Papageorgis, D. (1991) · Behaviour Research and Therapy · doi:10.1016/0005-7967(91)90087-j · Cited by 1,542 · see citing works
Depression, Disability Days, and Days Lost From Work in a Prospective Epidemiologic Survey
Broadhead, W. E. (1990) · JAMA · doi:10.1001/jama.1990.03450190056028 · Cited by 1,232 · see citing works
Katon, W. J. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00273-7 · Cited by 1,216 · see citing works
Journal of Psychiatry and Neuroscience
(2025) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn · Cited by 1,132 · see citing works
Kendler, K. S., Hettema, J. M., Butera, F., Gardner, C. O., & Prescott, C. A. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.8.789 · Cited by 966 · see citing works
Delivering interventions for depression by using the internet: randomised controlled trial
Christensen, H. (2004) · BMJ · doi:10.1136/bmj.37945.566632.ee · Cited by 928 · cited 20× · see citing works
“Christensen et al. (2004) evaluated the effectiveness of two Internet interventions for community-dwelling individuals with symptoms of depression: a PE website offering information about depression and an interactive website offering cognitive behavior therapy.”
BackgroundMethodInfluentialAnderson, I. M., Ferrier, I. N., Baldwin, R., Cowen, P. J., Howard, L. M., Lewis, G., Matthews, K., McAllister-Williams, H., Peveler, R. C., Scott, J. L., et al. (2008) · Journal of Psychopharmacology · doi:10.1177/0269881107088441 · Cited by 901 · see citing works
Colom, F., Vieta, E., Martínez‐Arán, A., Reinares, M., Goikolea, J. M., Benabarre, A., Torrent, C., Comes, M., Corbella, B., Parramón, G., et al. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.4.402 · Cited by 793 · see citing works
Prevalence and Treatment of Mental Disorders
MacKenzie, T. D., Kolpak, S. J., & Mehler, P. S. (2005) · New England Journal of Medicine · doi:10.1056/nejmc051936 · Cited by 650 · see citing works
The Role of the Primary Care Physician in Patientsʼ Adherence to Antidepressant Therapy
Lin, E., Korff, M. V., Katon, W. J., Bush, T., SIMON, G. E., WALKER, E., & ROBINSON, P. (1995) · Medical Care · doi:10.1097/00005650-199501000-00006 · Cited by 590 · see citing works
(1996) · American Journal of Psychiatry · doi:10.1176/ajp.153.11.1411 · Cited by 538 · see citing works
Souery, D., Oswald, P., Massat, I., Bailer, U., Bollen, J., Demyttenaere, K., Kasper, S., Lecrubier, Y., Montgomery, S., Serretti, A., et al. (2007) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v68n0713 · Cited by 521 · see citing works
The social consequences of psychiatric disorders, III: probability of marital stability
Kessler, R. C., Walters, E. E., & Forthofer, M. S. (1998) · American Journal of Psychiatry · doi:10.1176/ajp.155.8.1092 · Cited by 518 · see citing works
Meyer, B., Berger, T., Caspar, F., Beevers, C. G., Andersson, G., & Weiss, M. (2009) · Journal of Medical Internet Research · doi:10.2196/jmir.1151 · Cited by 363 · cited 19× · see citing works
“The model of Meyer et al. (2009) evaluated the effectiveness of Internet-based intervention in a RCT.”
BackgroundMethodInfluential[Long-term treatment of depression].
Keller, M. B. (1994) · PubMed · Cited by 362 · see citing works
A Randomized Trial of Relapse Prevention of Depression in Primary Care
Katon, W. J., Rutter, C. M., Ludman, E. J., Korff, M. V., Lin, E. H. B., Simon, G., Bush, T. M., Walker, E., & Unützer, J. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.3.241 · Cited by 292 · see citing works
Remission and relapse in major depression: a two-year prospective follow-up study
Ramana, R., Paykel, E. S., Cooper, Z., Hayhurst, H., Saxty, M., & Surtees, P. G. (1995) · Psychological Medicine · doi:10.1017/s0033291700033134 · Cited by 236 · cited 1× · see citing works
“Major depressive disorder (MDD) is a chronic, long-term disease with a high recurrence rate (Fleck et al., 2009; Kanai et al., 2003; Ramana et al., 1995).”
BackgroundDowrick, C., Dunn, G., Ayuso-Mateos, J. L., Dalgard, O. S., Page, H., Lehtinen, V., Casey, P., Wilkinson, C., Vazquez-Barquero, J. L., & Wilkinson, G. (2000) · BMJ · doi:10.1136/bmj.321.7274.1450 · Cited by 228 · see citing works
Brown, R. A., & Lewinsohn, P. M. (1984) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.52.5.774 · Cited by 202 · see citing works
Clarkin, J. F., Carpenter, D., Hull, J. W., Wilner, P. J., & Glick, I. D. (1998) · Psychiatric Services · doi:10.1176/ps.49.4.531 · Cited by 194 · see citing works
Kendler, K. S., Sheth, K. N., GARDNER, C. O., & Prescott, C. A. (2002) · Psychological Medicine · doi:10.1017/s0033291702006219 · Cited by 176 · see citing works
Butler, L. D., Waelde, L. C., Hastings, T. A., Chen, X., SYMONS, B. J., Marshall, J., Kaufman, A., Nagy, T. F., Blasey, C. M., Seibert, E. O., et al. (2008) · Journal of Clinical Psychology · doi:10.1002/jclp.20496 · Cited by 151 · see citing works
Depressive relapses and incomplete recovery from index episode
Faravelli, C., Ambonetti, A., Pallanti, S., & Pazzagli, A. (1986) · American Journal of Psychiatry · doi:10.1176/ajp.143.7.888 · Cited by 149 · see citing works
The compliance with antidepressants in general practice
Maddox, J. C., Levi, M., & Thompson, C. (1994) · Journal of Psychopharmacology · doi:10.1177/026988119400800108 · Cited by 148 · see citing works
Time to recurrence after recovery from major depressive episodes and its predictors
KANAI, T., Takeuchi, H., Furukawa, T. A., Yoshimura, R., Imaizumi, T., Kitamura, T., & Takahashi, K. (2003) · Psychological Medicine · doi:10.1017/s0033291703007827 · Cited by 138 · see citing works
Bipolar disorder and family communication: Effects of a psychoeducational treatment program.
Simoneau, T. L., Miklowitz, D. J., Richards, J. A., Saleem, R., & George, E. L. (1999) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.108.4.588 · Cited by 128 · see citing works
Psycho-education in bipolar disorder: effect on expressed emotion
Honig, A., Hofman, A., Rozendaal, N., & Dingemans, P. M. A. J. (1997) · Psychiatry Research · doi:10.1016/s0165-1781(97)00072-3 · Cited by 117 · see citing works
Cost-effectiveness of a program to prevent depression relapse in primary care
Simon, G. E., Von Korff, M., Ludman, E. J., Katon, W. J., Rutter, C., Unützer, J., Lin, E. H. B., Bush, T., & Walker, E. (2002) · Medical Care · doi:10.1097/00005650-200210000-00011 · Cited by 115 · see citing works
ANDERSON, C. M., Griffin, S. J., Rossi, A., PAGONIS, I., Holder, D., & Treiber, R. (1986) · Family Process · doi:10.1111/j.1545-5300.1986.00185.x · Cited by 112 · see citing works
Family Psychoeducation as an Evidence-Based Practice
Murray-Swank, A. B., & Dixon, L. B. (2004) · CNS Spectrums · doi:10.1017/s109285290000972x · Cited by 111 · see citing works
Fleck, M. P. D. A., Berlim, M. T., Lafer, B., Sougey, É. B., Porto, J. A. D., Brasil, M. A. A., Juruena, M. F., & Hetem, L. A. (2009) · Brazilian Journal of Psychiatry · doi:10.1590/s1516-44462009000500003 · Cited by 101 · see citing works
Self-citationKeeping therapies simple: psychoeducation in the prevention of relapse in affective disorders
Colom, F. (2011) · British Journal of Psychiatry · doi:10.1192/bjp.bp.110.090209 · Cited by 99 · see citing works
The Coping With Depression Course: Review and future directions.
Lewinsohn, P. M., Clarke, G. N., & Hoberman, H. M. (1989) · Canadian Journal of Behavioural Science / Revue canadienne des sciences du comportement · doi:10.1037/h0079846 · Cited by 95 · see citing works
Family psychoeducation for major depression: randomised controlled trial
Shimazu, K., Shimodera, S., Mino, Y., Nishida, A., Kamimura, N., Sawada, K., Fujita, H., Furukawa, T. A., & Inoue, S. (2011) · British Journal of Psychiatry · doi:10.1192/bjp.bp.110.078626 · Cited by 95 · cited 18× · see citing works
“A brief family PE is effective in the prevention of relapse (Shimazu et al., 2011) and a reduction of the psychosocial burden of relatives of patients with MDD (Katsuki et al., 2011).”
BackgroundMethodResultInfluentialBipolar disorder and family communication: Effects of a psychoeducational treatment program.
Simoneau, T. L., Miklowitz, D. J., Richards, J. A., et al. (1999) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.108.4.588 · Cited by 91 · see citing works
Effect on disability outcomes of a depression relapse prevention program
Von Korff, M., Katon, W., Rutter, C., Ludman, E., Simon, G., Lin, E., & Bush, T. (2003) · Psychosomatic Medicine · doi:10.1097/01.psy.0000097336.95046.0c · Cited by 81 · see citing works
Prediction of individual outcome in a group intervention for depression.
Steinmetz, J. L., Lewinsohn, P. M., & Antonuccio, D. O. (1983) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.51.3.331 · Cited by 74 · see citing works
Effectiveness in Psychiatric Care
Glick, I. D., Burti, L., Okonogi, K., et al. (1994) · The British Journal of Psychiatry · doi:10.1192/bjp.164.1.104 · Cited by 62 · see citing works
Relapse and Recurrence of Depression
Thase, M. E., & Sullivan, L. R. (1995) · CNS Drugs · doi:10.2165/00023210-199504040-00004 · Cited by 57 · see citing works
Prediction of individual outcome in a group intervention for depression.
Steinmetz, J. L., Lewinsohn, P. M., & Antonuccio, D. O. (1983) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.51.3.331 · Cited by 57 · see citing works
Pharmacotherapy to sustain the fully remitted state
Kennedy, S., McIntyre, R., Fallu, A., & Lam, R. (2002) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0245 · Cited by 56 · see citing works
Recovery from schizophrenia and the role of evidence-based psychosocial interventions
Corrigan, P. W. (2006) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.6.7.993 · Cited by 54 · see citing works
Swan, J., Sorrell, E., MacVicar, B., Durham, R., & Matthews, K. (2003) · Journal of Affective Disorders · doi:10.1016/j.jad.2003.09.002 · Cited by 49 · see citing works
Associação entre trauma por perda na infância e depressão na vida adulta
Zavaschi, M. L. S., Satler, F., Poester, D., Vargas, C. F., Piazenski, R., Rohde, L. A., & Eizirik, C. L. (2002) · Brazilian Journal of Psychiatry · doi:10.1590/s1516-44462002000400009 · Cited by 48 · see citing works
Efficacy of psychoeducation in bipolar patients: Systematic review of randomized trials.
Batista, T. A., Baes, C. V. W., & Juruena, M. F. (2011) · Psychology & Neuroscience · doi:10.3922/j.psns.2011.3.014 · Cited by 45 · see citing works
Self-citationAspectos neuropsicológicos da depressão
Rozenthal, M., Laks, J., & Engelhardt, E. (2004) · Revista de Psiquiatria do Rio Grande do Sul · doi:10.1590/s0101-81082004000200010 · Cited by 43 · see citing works
Shimodera, S., Inoue, S., Mino, Y., Tanaka, S., Kii, M., & Motoki, Y. (2000) · Psychiatry Research · doi:10.1016/s0165-1781(00)00193-1 · Cited by 43 · see citing works
Psychiatric Inpatients' Knowledge of Medication at Hospital Discharge
Clary, C. M., Dever, A., & Schweizer, E. E. (1992) · Psychiatric Services · doi:10.1176/ps.43.2.140 · Cited by 42 · see citing works
Katsuki, F., Takeuchi, H., Konishi, M., Sasaki, M., Murase, Y., Naito, A., Toyoda, H., Suzuki, M., Shiraishi, N., Kubota, Y., et al. (2011) · BMC Psychiatry · doi:10.1186/1471-244x-11-56 · Cited by 41 · see citing works
Dalgard, O. S. (2006) · Clinical Practice and Epidemiology in Mental Health · doi:10.1186/1745-0179-2-15 · Cited by 38 · see citing works
Lara, M. A., Navarro, C., Rubí, N. A., & Mondragón, L. (2003) · International Journal of Social Psychiatry · doi:10.1177/0020764003049001542 · Cited by 29 · see citing works
Medication compliance in a Chinese psychiatric out‐patient setting
Chan, D. W. (1984) · British Journal of Medical Psychology · doi:10.1111/j.2044-8341.1984.tb01585.x · Cited by 29 · see citing works
Luderer, H. J., & Böcker, F. M. (1993) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1993.tb03455.x · Cited by 28 · see citing works
Terapia cognitiva: abordagem para o transtorno afetivo bipolar
Juruena, M. F. (2001) · Cited by 19 · see citing works
Self-citationBenefits of Consumer Psychoeducation: A Pilot Program in South Africa
Seedat, S., Haskis, A., & Stein, D. J. (2008) · The International Journal of Psychiatry in Medicine · doi:10.2190/pm.38.1.c · Cited by 11 · see citing works
Cognitive-Behavioral Therapy for the Bipolar Disorder Patients
Juruena, M. F. (2012) · InTech eBooks · doi:10.5772/27379 · Cited by 3 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Lam, R. W., McIntosh, D., Wang, J., Enns, M. W., Kolivakis, T., Michalak, E. E., Sareen, J., Song, W.-Y., Kennedy, S. H., MacQueen, G. M., et al. (2016) · The Canadian Journal of Psychiatry · doi:10.1177/0706743716659416 · Cited by 288 · see citing works
Combining Psychedelic and Mindfulness Interventions: Synergies to Inform Clinical Practice
Payne, J. E., Chambers, R., & Liknaitzky, P. (2021) · ACS Pharmacology & Translational Science · doi:10.1021/acsptsci.1c00034 · Cited by 78 · see citing works
Strandskov, S. W., Ghaderi, A., Andersson, H., Parmskog, N., Hjort, E., Wärn, A. S., Jannert, M., & Andersson, G. (2017) · Behavior Therapy · doi:10.1016/j.beth.2017.02.002 · Cited by 68 · see citing works
Berg, M., Rozental, A., de Brun Mangs, J., Näsman, M., Strömberg, K., Viberg, L., Wallner, E., Åhman, H., Silfvernagel, K., Zetterqvist, M., et al. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00503 · Cited by 35 · see citing works
Siemann, I., Custers, J., van den Heuvel-Djulic, S., Pouwels, S., Kwakkenbos, L., & Spillekom-van Koulil, S. (2023) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2022.03.005 · Cited by 7 · see citing works
Mangelsdorf, S. N., Cagliarini, D., Lee, Y. Y., Mihalopoulos, C., Liu, V., Valentine, L., Bendall, S., Koval, P., D'Alfonso, S., Davey, C., et al. (2024) · BMJ Open · doi:10.1136/bmjopen-2024-088695 · Cited by 3 · see citing works
“35 The study team developed a web application called ‘Empower Your Mood’ (EYM) that includes psychoeducation modules on depression symptoms, causes and course, behaviour and mood, information on diet, exercise, sleep, social support and getting support.”
- Authors
- Tursi, M. F. D. S., Baes, C. V. W., Camacho, F. R. D. B., Tofoli, S. M. D. C., & Juruena, M. F.
- Affiliations
- Universidade de São Paulo (BR)
- Department of Neuroscience and Behavior, Faculty of Medicine of Ribeirão Preto, University of São Paulo, São Paulo, Brazil
- Venue
- Australian & New Zealand Journal of Psychiatry
- Publisher
- SAGE Publications
- Published
- 2013-06-05
- Volume
- 47
- Issue
- 11
- Pages
- 1019-1031
- ISSN
- 0004-8674 (ISSN-L)
- 1440-1614
- OpenAlex
- W2125452007
- Cited by
- 173
- References
- 64
- Citations by year
- 2026: 11 · 2025: 26 · 2024: 24 · 2023: 23 · 2022: 13 · 2021: 24 · 2020: 9 · 2019: 6 · 2018: 6 · 2017: 11 · 2016: 11 · 2015: 5 · 2014: 1 · 2013: 2
- FWCI
- 0.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Australian & New Zealand Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Research Portal (King's College London) (submittedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Disorders
- Keywords
- psychoeducation, major depressive disorder, medication adherence, family burden, psychosocial interventions, relapse and recurrence
- MeSH terms
- Depressive Disorder, Family, Humans, Patient Education as Topic, Psychotherapy, Treatment Outcome
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review