The DOI matches its Crossref record; 647 of the 648 references it cites were found in a registry or an index.
The 2020 Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders
Abstract
Objectives: To provide advice and guidance regarding the management of mood disorders, derived from scientific evidence and supplemented by expert clinical consensus to formulate s that maximise clinical utility. Methods: Articles and information sourced from search engines including PubMed, EMBASE, MEDLINE, PsycINFO and Google Scholar were supplemented by literature known to the mood disorders committee (e.g. books, book chapters and government reports) and from published depression and bipolar disorder guidelines. Relevant information was appraised and discussed in detail by members of the mood disorders committee, with a view to formulating and developing consensus-based recommendations and clinical guidance. The guidelines were subjected to rigorous consultation and external review involving: expert and clinical advisors, key stakeholders, professional bodies and specialist groups with interest in mood disorders. Results: The Royal Australian and New Zealand College of Psychiatrists mood disorders clinical practice guidelines 2020 (MDcpg 2020 ) provide up-to-date guidance regarding the management of mood disorders that is informed by evidence and clinical experience. The guideline is intended for clinical use by psychiatrists, psychologists, primary care physicians and others with an interest in mental health care. Conclusion: The MDcpg 2020 builds on the previous 2015 guidelines and maintains its joint focus on both depressive and bipolar disorders. It provides up-to-date recommendations and guidance within an evidence-based framework, supplemented by expert clinical consensus. Mood disorders committee: Gin S Malhi (Chair), Erica Bell, Darryl Bassett, Philip Boyce, Richard Bryant, Philip Hazell, Malcolm Hopwood, Bill Lyndon, Roger Mulder, Richard Porter, Ajeet B Singh and Greg Murray.
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“Two (10%) other CPGs stated that withdrawal symptoms and relapse should be differentiated from each other when discontinuing antidepressants, but without considering the potential overlap of symptoms between these situations.3,44”
From Clinical practice guideline recommendations on tapering and discontinuing antidepressants for depression: a systematic review (2022) · cites this paper as [3]
In the citing paper
“one (5%) of the CPGs suggested that patients in high risk of severe discontinuation symptoms reduce the dose first to the minimal effective dose, then halve that dose, and then ‘reduce more slowly in small decrements, allowing 2 weeks for each dose reduction, according to how the tablet can be divided. [...] once minimum effective dose is achieved, reduce the dose by no more than 50% weekly’. 3”
From Clinical practice guideline recommendations on tapering and discontinuing antidepressants for depression: a systematic review (2022) · cites this paper as [3]
In the citing paper
“and for tapering tricyclic antidepressants in one (5%) of the CPGs, recommending ‘a slow taper over a longer period of time’. 3”
From Clinical practice guideline recommendations on tapering and discontinuing antidepressants for depression: a systematic review (2022) · cites this paper as [3]
In the citing paper
“Only two (10%) of the CPGs, however, explicitly recommended that patients should discontinue their antidepressant after maintenance treatment 3 or continuation treatment; 28”
From Clinical practice guideline recommendations on tapering and discontinuing antidepressants for depression: a systematic review (2022) · cites this paper as [3]
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Malhi, G. S., Bell, E., Bassett, D. L., Boyce, P. M., Hopwood, M., Murray, G., Mulder, R., Singh, A., & Porter, R. (2021) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/00048674211010262 · Cited by 1
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Preface: How to Use This Handbook
Meyer, J. M., & Stahl, S. M. (2023) · doi:10.1017/9781009225069.002
Meyer, J. M., & Stahl, S. M. (2023) · Cambridge University Press eBooks · doi:10.1017/9781009225069.004
Haitana, T., Clark, M. T. R., Crowe, M., Cunningham, R., Porter, R., Pitama, S. G., Mulder, R., & Lacey, C. J. (2024) · Healthcare · doi:10.3390/healthcare12070793 · Cited by 1
“This study extends beyond recent psychiatrically oriented clinical practice guidelines for the treatment of BD, by describing an approach to mental health service provision recommended by key informants to address existing inequities and meet M¯aori health needs [2].”
BackgroundInfluentialSelf-citationTakeshima, M., Umakoshi, A., Omori, Y., Yoshizawa, K., Ogasawara, M., Kudo, M., Itoh, Y., Ayabe, N., & Mishima, K. (2024) · Psychopharmacology · doi:10.1007/s00213-024-06581-1
Tennant, M. A., Frampton, C. M., Mulder, R., Eggleston, K., & Beaglehole, B. (2024) · New Zealand Medical Journal · doi:10.26635/6965.6544
Self-citationGandhi, S., Craig, S. S., & Gordon, M. (2024) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/00048674241268229
Emotional Response to Various Exercise Types in Patients With Mental Disorders
Nemoto, M., Nemoto, K., Sasai, H., Ota, M., Haneda, M., Sekine, A., & Arai, T. (2024) · Cureus · doi:10.7759/cureus.75371
Electroconvulsive Therapy - History and Current Use in Psychiatry: A Literature Review
Czerniak, P., Buszek, J., Kosel, A., Kamińska, W., Bobrzyk, A., Smółka, M., Rumian, M., Antoszewska, A., Bargieł, W., & Bąk, D. (2024) · Archiv Euromedica · doi:10.35630/2024/14/6.610
Emerging Treatments for Bipolar Disorder
Yalın, N., Young, A. H., & Zarate, C. A. (2025) · doi:10.1093/med/9780197640654.003.0026
Hetrick, S. E., Berk, M., Dean, O. M., Chanen, A., McGorry, P., Cotton, S. M., Torok, M., Catania, L. S., Davey, C. G., & Witt, K. G. (2026) · European Child and Adolescent Psychiatry · doi:10.1007/s00787-026-03032-4
“Cognitive behaviour therapy (CBT), either alone or in combination with adjunctive pharmacotherapy, is an effec - tive first-line treatment for major depression [ 6], including for young people [7], and is recommended in clinical practice guidelines in Australia [8] and internationally [9–11].”
Russell, S. E., Wrobel, A. L., Skvarc, D., Lotfaliany, M., Dean, O. M., Ashton, M. M., Magalhães, P. V. D. S., Nierenberg, A. A., Berk, M., & Turner, A. (2025) · Bipolar Disorders · doi:10.1111/bdi.70002
“…Health and Care Excellence and the United States Veteran Affairs Department of Defence clinical practice guidelines recommend treating people with BD with a combination of pharmacotherapy, psychotherapy and life-style adjustments, including sleep, exercise and healthy eating habits [10, 14, 18].”
InfluentialCrowe, M., Jordan, J., Porter, R., Douglas, K. M., Lacey, C. J., Thwaites, B., & Sillifant, B. (2025) · Counselling and Psychotherapy Research · doi:10.1002/capr.12906 · Cited by 1
Self-citationDunn, A., & Pearson, C. (2025) · Advances in Mental Health · doi:10.1080/18387357.2025.2469505
Miljevic, A., Hoath, K., Leggett, K. S., Hennessy, L. A., Boax, C. A., Hryniewicki, J., & Rodger, J. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1513339
Lifestyle in Mental and Physical Disorders
Suetani, S., Marx, W., & Siskind, D. J. (2025) · Springer eBooks · doi:10.1007/978-3-031-81802-8_14
Tundo, A., Betrò, S., de Filippis, R., Felici, R., Lucangeli, C., & Iommi, M. (2025) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0000000000001986 · Cited by 1
Coët, A., Blampied, F. M., & Rucklidge, J. J. (2025) · Journal of Affective Disorders Reports · doi:10.1016/j.jadr.2025.100913
(2025) · Wiley eBooks · doi:10.1002/9781119870203.mpg002.pub2
Depressão e subtratamento em pessoas com HIV AIDS
Dal-Bó, M. J., Medeiros, L. K., Dal-Bó, B. P. M. D. A., Rezin, G. T., & da Silva, R. M. (2025) · Debates em Psiquiatria · doi:10.25118/2763-9037.2025.v15.1398
Abordaje clínico y terapéutico del trastorno bipolar en España: una encuesta nacional
Sierra, P. (2025) · Psiquiatría Biológica · doi:10.1016/j.psiq.2025.100728
Sawalha, R., Al-Samawy, S., Mahmoud, Z., Tadorian, C., Levi, C. R., Spratt, N. J., Hosseinzadeh, H., & Bajorek, B. V. (2025) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-025-03845-3
“Five guidelines recognised cultural identity and ethnicity as risk factors for certain diseases [34, 36, 37, 43, 46], while one guideline on prostate cancer highlighted that CALD populations face lower risks of prostate cancer and associated mortality compared to Australian-born men [35].”
InfluentialPsychotherapy is mostly harmless but not totally harmless: Implications for India
Kakunje, A., Dewani, K., Srinivasa, P., & Gowda, M. (2025) · Indian Journal of Psychiatry · doi:10.4103/indianjpsychiatry.indianjpsychiatry_291_25
What Not to Use in the Pharmacological Treatment of Bipolar Disorder
Palma, N., & Gomes, F. A. (2025) · Springer eBooks · doi:10.1007/978-3-031-85519-1_25
Electroconvulsive therapy and autobiographical memory
Scott, R. J., Prowacki, S., & Purushothaman, S. (2025) · Psychiatry Psychology and Law · doi:10.1080/13218719.2025.2486082
“In 2020, the Royal Australian and New Zealand College of Psychiatrists published Clinical Practice Guidelines for the Management of Mood Disorders (RANZCP Mood Disorder Guidelines ) which recommended ECT for the treatment of mania when pharmacological management was unsuccessful (285,286).”
Kuwabara, Y., Imamoto, A., Hori, N., Kim, H., Kinjo, A., & Osaki, Y. (2025) · Pediatrics International · doi:10.1111/ped.70063 · Cited by 1
“46 As a precautionary approach, managing the time spent on digital device use in a manner that does not disrupt basic lifestyle habits is important for mental health maintenance.”
Nuances in the Management of Bipolar Disorder
Grover, S. (2025) · Journal of Mental Health and Human Behaviour · doi:10.4103/jmhhb.jmhhb_135_25
Ellis, K. A., Lai, R., Curran, E. M., Southam, J., Moorhead, R. A., Cox, K. L., Mancuso, S. G., Westphal, A., Chong, T. W. H., Rego, T. W. H., et al. (2025) · doi:10.2196/preprints.80040
Mania and maintenance treatments of bipolar disorders
Vázquez, G. H. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-33580-8.00019-2
Metadata
- Authors
- Malhi, G. S., Bell, E., Bassett, D., Boyce, P., Bryant, R., Hazell, P., Hopwood, M., Lyndon, B., Mulder, R., Porter, R., Singh, A. B., & Murray, G.
- Affiliations
- The University of Sydney (AU)
- Consultant Psychiatrist, Perth, WA, Australia
- UNSW Sydney (AU)
- The University of Melbourne (AU)
- University of Otago (NZ)
- Deakin University (AU)
- Swinburne University of Technology (AU)
- Corresponding author
- Malhi, Gin S
- ORCID
- Venue
- Australian & New Zealand Journal of Psychiatry
- Publisher
- SAGE Publications
- Published
- 2020-12-22
- Volume
- 55
- Issue
- 1
- Pages
- 7-117
- ISSN
- 0004-8674 (ISSN-L)
- 1440-1614
- OpenAlex
- W3145708260
- Semantic Scholar
- aebe450498c0d007898716e02f680b40b9ae3f78
- Cited by
- 614
- References
- 648
- Citations by year
- 2026: 115 · 2025: 131 · 2024: 101 · 2023: 117 · 2022: 82 · 2021: 65 · 2020: 3
- FWCI
- 40.01
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Australian & New Zealand Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Swinburne figshare (Swinburne University of Technology) (submittedVersion)
- Funders
- RANZCP
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Clinical practice guidelines implementation
- Keywords
- mood disorders, depression, bipolar disorder, depression treatment, bipolar disorder management
- MeSH terms
- Australia, Humans, New Zealand, Psychiatry, Societies, Medical, Practice Guidelines as Topic, Mood Disorders
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