The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Aging and Bone
Open accessAbstract
Bones provide mechanical and protective function, while also serving as housing for marrow and a site for regulation of calcium ion homeostasis. The properties of bones do not remain constant with age; rather, they change throughout life, in some cases improving in function, but in others, function deteriorates. Here we review the modifications in the mechanical function and shape of bones, the bone cells, the matrix they produce, and the mineral that is deposited on this matrix, while presenting recent theories about the factors leading to these changes.
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Citations
Cites
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Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis
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“However, mice from the third generation and beyond exhibited systemic impaired organ function, tissue atrophy, and classic age-related disorders such as osteoporosis (Lee et al., 1998).”
BackgroundOsteocytes, mechanosensing and Wnt signaling
Bonewald, L. F., & Johnson, M. L. (2008) · Bone · doi:10.1016/j.bone.2007.12.224 · Cited by 1,076
Linking functional decline of telomeres, mitochondria and stem cells during ageing
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Cited by
Robling, A. G., & Bonewald, L. F. (2020) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021119-034332 · Cited by 539
Bone composition: relationship to bone fragility and antiosteoporotic drug effects
Boskey, A. L. (2013) · BoneKEy Reports · doi:10.1038/bonekey.2013.181 · Cited by 424
Self-citationCurrent Status of the Diagnosis and Management of Osteoporosis
Aibar-Almazán, A., Voltes-Martínez, A., Castellote-Caballero, Y., Afanador-Restrepo, D. F., Carcelén-Fraile, M. D. C., & López-Ruiz, E. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23169465 · Cited by 412
Aged skeletal stem cells generate an inflammatory degenerative niche
Ambrosi, T. H., Marecic, O., McArdle, A., Sinha, R., Gulati, G. S., Tong, X., Wang, Y., Steininger, H. M., Hoover, M. Y., Koepke, L. S., et al. (2021) · Nature · doi:10.1038/s41586-021-03795-7 · Cited by 392
Mesenchymal stem cells: Amazing remedies for bone and cartilage defects
Kangari, P., Talaei-Khozani, T., Razeghian-Jahromi, I., & Razmkhah, M. (2020) · Stem Cell Research & Therapy · doi:10.1186/s13287-020-02001-1 · Cited by 286
Metadata
- Authors
- Boskey, A. L., & Coleman, R.
- Venue
- Journal of Dental Research
- Publisher
- SAGE Publications
- Published
- 2010-10-05
- Volume
- 89
- Issue
- 12
- Pages
- 1333-1348
- ISSN
- 0022-0345 (ISSN-L)
- 1544-0591
- OpenAlex
- W2169887586
- Cited by
- 553
- References
- 16
- FWCI
- 8.34
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
