The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Microbial Geography of the Oral Cavity
Abstract
We aimed to determine the bacterial diversity of different oral micro-niches and to assess whether saliva and plaque samples are representative of oral microbial composition. We took minute samples from each surface of the individual teeth and gingival crevices of two healthy volunteers (112 samples per donor), as well as samples from the tongue dorsum and non-stimulated and stimulated saliva. DNA was extracted from 67 selected samples of each donor, and the 16S rRNA gene was amplified by PCR and pyrosequenced to obtain, on average, over 2,700 reads per sample, which were taxonomically assigned to obtain a geographic map of bacterial diversity at each tooth and sulcus location. Analysis of the data shows considerable differences in bacterial composition between teeth at different intra-oral locations and between surfaces of the same tooth. The most pronounced differences were observed in incisors and canines, where genera like Streptococcus were found at 40% to 70% on the vestibular surfaces but were almost absent on the lingual sides. Saliva samples, especially non-stimulated saliva, were not representative of supra-and subgingival plaque in the two individuals tested. We suggest that more precise sampling is required for the proper determination of oral microbial composition and to relate that diversity to epidemiological, clinical, and etiological parameters.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Schloss, P. D., Westcott, S. L., Ryabin, T., Hall, J. R., Hartmann, M., Hollister, E. B., Lesniewski, R. A., Oakley, B. B., Parks, D. H., Robinson, C. J., et al. (2009) · Applied and Environmental Microbiology · doi:10.1128/aem.01541-09 · Cited by 19,549
Structure, function and diversity of the healthy human microbiome
The Human Microbiome Project Consortium (2012) · Nature · doi:10.1038/nature11234 · Cited by 11,726
The Ribosomal Database Project: improved alignments and new tools for rRNA analysis
Cole, J. R., Wang, Q., Cardenas, E., Fish, J., Chai, B., Farris, R. J., Kulam-Syed-Mohideen, A. S., McGarrell, D. M., Marsh, T., Garrity, G. M., et al. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkn879 · Cited by 4,762
Defining the normal bacterial flora of the oral cavity
Aas, J. A., Paster, B. J., Stokes, L. N., Olsen, I., & Dewhirst, F. E. (2005) · Journal of Clinical Microbiology · doi:10.1128/jcm.43.11.5721-5732.2005 · Cited by 3,092
UniFrac – An online tool for comparing microbial community diversity in a phylogenetic context
Lozupone, C., Hamady, M., & Knight, R. (2006) · BMC Bioinformatics · doi:10.1186/1471-2105-7-371 · Cited by 1,453
Defining the healthy “core microbiome” of oral microbial communities
Zaura, E., Keijser, B. J., Huse, S. M., & Crielaard, W. (2009) · BMC Microbiology · doi:10.1186/1471-2180-9-259 · Cited by 1,323
The Role of Bacteria in the Caries Process: Ecological Perspectives
Takahashi, N., & Nyvad, B. (2011) · Journal of Dental Research · doi:10.1177/0022034510379602 · Cited by 1,199
Self-citationSegata, N., Haake, S. K., Mannon, P., Lemon, K. P., Waldron, L., Gevers, D., Huttenhower, C., & Izard, J. (2012) · Genome Biology · doi:10.1186/gb-2012-13-6-r42 · Cited by 1,076
Bacteria of Dental Caries in Primary and Permanent Teeth in Children and Young Adults
Aas, J. A., Griffen, A. L., Dardis, S. R., Lee, A. M., Olsen, I., Dewhirst, F. E., Leys, E. J., & Paster, B. J. (2008) · Journal of Clinical Microbiology · doi:10.1128/jcm.01410-07 · Cited by 952 · cited 4×
“Carious cavities, for instance, have been found to harbor a different set of bacterial species than dental plaque at sound surfaces, and the bacterial composition varies among enamel, dentin, and deep dentin samples (Aas et al., 2008; Belda-Ferre et al., 2012).”
BackgroundInfluentialYarza, P., Richter, M., Peplies, J., Euzeby, J., Amann, R., Schleifer, K.-H., Ludwig, W., Glöckner, F. O., & Rosselló-Móra, R. (2008) · Systematic and Applied Microbiology · doi:10.1016/j.syapm.2008.07.001 · Cited by 931
Cited by
The Oral Microbiota: Dynamic Communities and Host Interactions
Lamont, R. J., Koo, H., & Hajishengallis, G. (2018) · Nature Reviews Microbiology · doi:10.1038/s41579-018-0089-x · Cited by 2,217
The oral microbiome and the immunobiology of periodontal disease and caries
Costalonga, M., & Herzberg, M. C. (2014) · Immunology Letters · doi:10.1016/j.imlet.2014.08.017 · Cited by 645
Metatranscriptomics of the Human Oral Microbiome during Health and Disease
Jorth, P., Turner, K. H., Gumus, P., Nizam, N., Buduneli, N., & Whiteley, M. (2014) · mBio · doi:10.1128/mbio.01012-14 · Cited by 386
The Oral Microbiota: Community Composition, Influencing Factors, Pathogenesis, and Interventions
Li, X., Liu, Y., Yang, X., Li, C., & Song, Z. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.895537 · Cited by 328
Biogeography of the Oral Microbiome: The Site-Specialist Hypothesis
Mark Welch, J. L., Dewhirst, F. E., & Borisy, G. G. (2019) · Annual Review of Microbiology · doi:10.1146/annurev-micro-090817-062503 · Cited by 284
Metadata
- Authors
- Simón-Soro, Á., Tomás, I., Cabrera-Rubio, R., Catalan, M. D., Nyvad, B., & Mira, A.
- Venue
- Journal of Dental Research
- Publisher
- SAGE Publications
- Published
- 2013-05-14
- Volume
- 92
- Issue
- 7
- Pages
- 616-621
- ISSN
- 0022-0345 (ISSN-L)
- 1544-0591
- OpenAlex
- W1975560947
- Cited by
- 280
- References
- 27
- FWCI
- 21.47
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Microbial Geography of the Oral Cavity. https://app.cochat.ai/papers/10.1177/0022034513488119
- The paper
- Simón-Soro, Á., Tomás, I., Cabrera-Rubio, R., Catalan, M. D., Nyvad, B., & Mira, A. (2013). Microbial Geography of the Oral Cavity. Journal of Dental Research. https://doi.org/10.1177/0022034513488119
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
