Benzodiazepines: Risks and Benefits. A Reconsideration
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Over the last decade there have been further developments in our knowledge of the risks and benefits of benzodiazepines, and of the risks and benefits of alternatives to benzodiazepines. Representatives drawn from the Psychopharmacology Special Interest Group of the Royal College of Psychiatrists and the British Association for Psychopharmacology together examined these developments, and have provided this joint statement with recommendations for clinical practice. The working group was mindful of widespread concerns about benzodiazepines and related anxiolytic and hypnotic drugs. The group believes that whenever benzodiazepines are prescribed, the potential for dependence or other harmful effects must be considered. However, the group also believes that the risks of dependence associated with long-term use should be balanced against the benefits that in many cases follow from the short or intermittent use of benzodiazepines and the risk of the underlying conditions for which treatment is being provided.
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Benzodiazepines are effective in the acute treatment of generalized anxiety disorder, social anxiety, panic disorder, and insomnia.
“They have been shown to be effective in the acute treatment of generalized anxiety disorder, social anxiety, panic disorder, and insomnia [8].”
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- Authors
- Baldwin, D. S., Aitchison, K., Bateson, A., Curran, H. V., Davies, S., Leonard, B., Nutt, D. J., Stephens, D. N., & Wilson, S.
- Affiliations
- University of Southampton (GB)
- University of Alberta (CA)
- Ross University School of Medicine (BB)
- University College London (GB)
- Centre for Addiction and Mental Health (CA)
- Ollscoil na Gaillimhe – University of Galway (IE)
- Imperial College London (GB)
- University of Sussex (GB)
- Corresponding author
- Baldwin, David S
- ORCID
- Venue
- Journal of Psychopharmacology
- Publisher
- SAGE Publications
- Published
- 2013-09-24
- Volume
- 27
- Issue
- 11
- Pages
- 967-971
- ISSN
- 0269-8811 (ISSN-L)
- 1461-7285
- OpenAlex
- W2116273170
- Cited by
- 249
- References
- 7
- Citations by year
- 2026: 17 · 2025: 19 · 2024: 14 · 2023: 21 · 2022: 21 · 2021: 22 · 2020: 23 · 2019: 21 · 2018: 21 · 2017: 19 · 2016: 19 · 2015: 16 · 2014: 15 · 2012: 1
- FWCI
- 22.52
- Type
- journal article
- Language
- en
- Open access
- green
- figshare.com
- Locations
- Journal of Psychopharmacology (publishedVersion)
- PubMed (publishedVersion)
- ePrints Soton (University of Southampton) (acceptedVersion)
- Research Bank (Australian Catholic University) (submittedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Figshare (submittedVersion, cc-by)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- benzodiazepines, anxiolytics, hypnotics, benzodiazepine dependence, long-term benzodiazepine use, benefits and risks, clinical guidelines, anxiety disorders, insomnia
- MeSH terms
- Benzodiazepines, Humans, Hypnotics and Sedatives, Practice Guidelines as Topic, Risk Assessment
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