The DOI matches its Crossref record; 243 of the 243 references it cites were found in a registry or an index.
Molecular pathophysiology of cerebral edema
Open accessAbstract
Advancements in molecular biology have led to a greater understanding of the individual proteins responsible for generating cerebral edema. In large part, the study of cerebral edema is the study of maladaptive ion transport. Following acute CNS injury, cells of the neurovascular unit, particularly brain endothelial cells and astrocytes, undergo a program of pre- and post-transcriptional changes in the activity of ion channels and transporters. These changes can result in maladaptive ion transport and the generation of abnormal osmotic forces that, ultimately, manifest as cerebral edema. This review discusses past models and current knowledge regarding the molecular and cellular pathophysiology of cerebral edema.
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Cited by
Takata, F., Nakagawa, S., Matsumoto, J., & Dohgu, S. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.661838 · Cited by 651
Cerebrospinal fluid influx drives acute ischemic tissue swelling
Mestre, H., Du, T., Sweeney, A. M., Liu, G., Samson, A. J., Peng, W., Mortensen, K. N., Stæger, F. F., Bork, P. A. R., Bashford, L., et al. (2020) · Science · doi:10.1126/science.aax7171 · Cited by 494
Emerging roles for dynamic aquaporin-4 subcellular relocalization in CNS water homeostasis
Salman, M. M., Kitchen, P., Halsey, A., Wang, M. X., Törnroth-Horsefield, S., Conner, A. C., Badaut, J., Iliff, J. J., & Bill, R. M. (2022) · Brain · doi:10.1093/brain/awab311 · Cited by 303
Early postmortem brain MRI findings in COVID-19 non-survivors
Coolen, T., Lolli, V., Sadeghi, N., Rovaï, A., Trotta, N., Taccone, F. S., Creteur, J., Henrard, S., Goffard, J.-C., De Witte, O., et al. (2020) · doi:10.1101/2020.05.04.20090316 · Cited by 256
Heterogeneity of Astrocytes in Grey and White Matter
Köhler, S., Winkler, U., & Hirrlinger, J. (2021) · Neurochemical Research · doi:10.1007/s11064-019-02926-x · Cited by 123
Metadata
- Authors
- Stokum, J. A., Gerzanich, V., & Simard, J. M.
- Venue
- Journal of Cerebral Blood Flow & Metabolism
- Publisher
- SAGE Publications
- Published
- 2015-11-16
- Volume
- 36
- Issue
- 3
- Pages
- 513-538
- ISSN
- 0271-678X (ISSN-L)
- 1559-7016
- OpenAlex
- W2291424342
- Cited by
- 587
- References
- 243
- FWCI
- 13.40
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Stokum, J. A., Gerzanich, V., & Simard, J. M. (2016). Molecular pathophysiology of cerebral edema. Journal of Cerebral Blood Flow & Metabolism. https://doi.org/10.1177/0271678x15617172
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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