Cited by 367Tendon Structure and TreatmentKnee injuries and reconstruction techniquesSports injuries and prevention

Medial collateral ligament healing: A multidisciplinary assessment in rabbits

Frank, C., Woo, S.L.-Y., Amiel, D., Harwood, F., Gomez, M., Akeson, W.·1983·The American Journal of Sports Medicine

Abstract

Medial collateral ligament healing without treatment has been studied in a rabbit model. Complete midsubstance gaps were found to heal by distinct scar formation over time. This healing process was fast since the gap was bridged quickly; however, more subtle changes in ap pearance of the healing tissue continued for many months. The ligament "scar" was found to be structur ally abnormal chemically and mechanically even at long- term followup. A plateau in its improvement suggests that the scar may never approach normal ligament characteristics (without treatment). A baseline of liga ment healing by scar formation has been established.

Integrity signals

Registry

Crossref · 10.1177/036354658301100602

Cites

62 of 62 references verified0 citation errors · 0 not checkable

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Authors
Frank, C., Woo, S. L.-Y., Amiel, D., Harwood, F., Gomez, M., & Akeson, W.
Affiliations
  • University of California San Diego (US)
  • United States Department of Veterans Affairs (US)
Venue
The American Journal of Sports Medicine
Published
1983-11
Volume
11
Issue
6
Pages
379-389
ISSN
  • 0363-5465 (ISSN-L)
  • 1552-3365
OpenAlex
W2052694074
Cited by
367
References
62
Citations by year
2026: 3 · 2025: 1 · 2024: 2 · 2023: 6 · 2022: 4 · 2021: 7 · 2020: 5 · 2019: 10 · 2018: 11 · 2017: 9 · 2016: 8 · 2015: 5 · 2014: 8 · 2013: 16 · 2012: 8
FWCI
5.04
Type
journal article
Language
en
Open access
closed
Locations
  • The American Journal of Sports Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Tendon Structure and Treatment
  • Health Sciences › Medicine › Surgery › Knee injuries and reconstruction techniques
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports injuries and prevention
Keywords
medial collateral ligament, ligament healing, scar formation, rabbit model, ligament biomechanics
MeSH terms
Animals, Biomechanical Phenomena, Body Water, Cicatrix, Collagen, DNA, Glycosaminoglycans, Knee Joint, Ligaments, Articular, Male, Rabbits, Wound Healing

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